| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lisha Chang, Wan Zhang, Songxin Shi, Yanbo Peng, Dali Wang, Li Zhang, Jiang Zhan. microRNA-195 attenuates neuronal apoptosis in rats with ischemic stroke through inhibiting KLF5-mediated activation of the JNK signaling pathway. Molecular medicine (Cambridge, Mass.). vol 26. issue 1. 2021-06-25. PMID:32272873. |
microrna-195 attenuates neuronal apoptosis in rats with ischemic stroke through inhibiting klf5-mediated activation of the jnk signaling pathway. |
2021-06-25 |
2023-08-13 |
rat |
| Lisha Chang, Wan Zhang, Songxin Shi, Yanbo Peng, Dali Wang, Li Zhang, Jiang Zhan. microRNA-195 attenuates neuronal apoptosis in rats with ischemic stroke through inhibiting KLF5-mediated activation of the JNK signaling pathway. Molecular medicine (Cambridge, Mass.). vol 26. issue 1. 2021-06-25. PMID:32272873. |
the current study aimed to elucidate the role of microrna-195 (mir-195) in neuronal apoptosis and brain plasticity in rats with ischemic stroke via the jnk signaling pathway/klf5 axis. |
2021-06-25 |
2023-08-13 |
rat |
| Blaise Cozene, Nadia Sadanandan, Bella Gonzales-Portillo, Madeline Saft, Justin Cho, You Jeong Park, Cesar V Borlonga. An Extra Breath of Fresh Air: Hyperbaric Oxygenation as a Stroke Therapeutic. Biomolecules. vol 10. issue 9. 2021-06-24. PMID:32899709. |
the use of hyperbaric oxygen therapy (hbot) demonstrates pre-clinical effectiveness for the treatment of acute ischemic stroke and reports reductions in oxidative stress, inflammation, and neural apoptosis. |
2021-06-24 |
2023-08-13 |
Not clear |
| Hui Yang, He Wang, Xiaodan Zhang, Yuehan Yang, Hongbin L. Upregulated LINC00319 aggravates neuronal injury induced by oxygen-glucose deprivation via modulating miR-200a-3p. Experimental and therapeutic medicine. vol 22. issue 2. 2021-06-22. PMID:34149890. |
collectively, the present results suggested that linc00319 promoted apoptosis and aggravated neuronal injury induced by ogd by regulating mir-200a-3p, which may be important for ischemic stroke treatment. |
2021-06-22 |
2023-08-13 |
Not clear |
| Yongxing Lai, Peiqiang Lin, Manli Chen, Yixian Zhang, Jianhao Chen, Mouwei Zheng, Ji Liu, Houwei Du, Ronghua Chen, Xiaodong Pan, Nan Liu, Hongbin Che. Restoration of L-OPA1 alleviates acute ischemic stroke injury in rats via inhibiting neuronal apoptosis and preserving mitochondrial function. Redox biology. vol 34. 2021-06-18. PMID:32199783. |
restoration of l-opa1 alleviates acute ischemic stroke injury in rats via inhibiting neuronal apoptosis and preserving mitochondrial function. |
2021-06-18 |
2023-08-13 |
rat |
| Yang Li, Xuepeng Zhang, Aijia Ma, Yan Kan. Rational Application of β-Hydroxybutyrate Attenuates Ischemic Stroke by Suppressing Oxidative Stress and Mitochondrial-Dependent Apoptosis via Activation of the Erk/CREB/eNOS Pathway. ACS chemical neuroscience. vol 12. issue 7. 2021-06-18. PMID:33739811. |
rational application of β-hydroxybutyrate attenuates ischemic stroke by suppressing oxidative stress and mitochondrial-dependent apoptosis via activation of the erk/creb/enos pathway. |
2021-06-18 |
2023-08-13 |
rat |
| Mitchell J Brun, Kefan Song, Byunguk Kang, Cooper Lueck, Weitong Chen, Kaitlyn Thatcher, Erhe Gao, Walter J Koch, Joy Lincoln, Sudarsan Rajan, Junghae Su. Constructing and evaluating caspase-activatable adeno-associated virus vector for gene delivery to the injured heart. Journal of controlled release : official journal of the Controlled Release Society. vol 328. 2021-06-17. PMID:33157191. |
here, we have designed a provector that is activated by cysteine aspartic proteases (caspases), which have roles in inflammation and apoptosis and thus are elevated at sites of diseases such as heart failure, neurodegenerative diseases, and ischemic stroke. |
2021-06-17 |
2023-08-13 |
Not clear |
| Xi Chen, Hansen Chen, Yachong He, Shuping Fu, Haosheng Liu, Qi Wang, Jiangang She. Proteomics-Guided Study on Buyang Huanwu Decoction for Its Neuroprotective and Neurogenic Mechanisms for Transient Ischemic Stroke: Involvements of EGFR/PI3K/Akt/Bad/14-3-3 and Jak2/Stat3/Cyclin D1 Signaling Cascades. Molecular neurobiology. vol 57. issue 10. 2021-06-09. PMID:32700252. |
in the present study, we investigated the effects of bhd on inhibiting neuronal apoptosis, promoting proliferation and differentiation of neural stem cells (nscs) and neurite formation and enhancing learning and memory functional recovery in an experimental rat ischemic stroke model. |
2021-06-09 |
2023-08-13 |
rat |
| Ertan Comertpay, Sevilay Vural, Oğuz Eroğlu, Nermin Dindar Badem, Yasemin Karadeniz Bilgili, Figen Coşku. The Diagnostic Value of sTWEAK in Acute Ischemic Stroke Balkan medical journal. vol 37. issue 6. 2021-06-09. PMID:32856885. |
soluble tumor necrosis factor-like weak inducer of apoptosis, a protein involved in the regulation of several biological functions, could be a potential acute ischemic stroke biomarker. |
2021-06-09 |
2023-08-13 |
Not clear |
| Meiping Wang, Wenjuan Chen, Yu Geng, Chenghua Xu, Xiaoxiao Tao, Yi Zhan. Long Non-Coding RNA MEG3 Promotes Apoptosis of Vascular Cells and is Associated with Poor Prognosis in Ischemic Stroke. Journal of atherosclerosis and thrombosis. vol 27. issue 7. 2021-05-28. PMID:31656272. |
long non-coding rna meg3 promotes apoptosis of vascular cells and is associated with poor prognosis in ischemic stroke. |
2021-05-28 |
2023-08-13 |
Not clear |
| Meihua Wang, Zhilin Chen, Lei Yang, Lei Din. Sappanone A Protects Against Inflammation, Oxidative Stress and Apoptosis in Cerebral Ischemia-Reperfusion Injury by Alleviating Endoplasmic Reticulum Stress. Inflammation. vol 44. issue 3. 2021-05-24. PMID:33411101. |
these results demonstrated that sa alleviates endoplasmic reticulum stress, ameliorating inflammation, oxidative stress, and apoptosis, and thereby serves as therapeutic potential for protection against cerebral ischemia-reperfusion injury in ischemic stroke. |
2021-05-24 |
2023-08-13 |
rat |
| Yan Sun, Hai Chen, Yibing Li. Rehabilitation training inhibits neuronal apoptosis by down-regulation of TLR4/MyD88 signaling pathway in mice with cerebral ischemic stroke. American journal of translational research. vol 13. issue 4. 2021-05-23. PMID:34017384. |
rehabilitation training inhibits neuronal apoptosis by down-regulation of tlr4/myd88 signaling pathway in mice with cerebral ischemic stroke. |
2021-05-23 |
2023-08-13 |
mouse |
| Yan Sun, Hai Chen, Yibing Li. Rehabilitation training inhibits neuronal apoptosis by down-regulation of TLR4/MyD88 signaling pathway in mice with cerebral ischemic stroke. American journal of translational research. vol 13. issue 4. 2021-05-23. PMID:34017384. |
to investigate the role of rehabilitation training and tlr4/myd88 signaling pathway on neuronal apoptosis in mice with cerebral ischemic stroke. |
2021-05-23 |
2023-08-13 |
mouse |
| Xiao-Yu Zhu, Bo Xia, Ting Ye, Ming-Zhu Dai, Hua Yang, Chun-Qi Li, Ping L. Ponatinib-induced ischemic stroke in larval zebrafish for drug screening. European journal of pharmacology. vol 889. 2021-05-14. PMID:32668288. |
this zebrafish ischemic stroke had the cerebral vascular endothelial injury, thrombosis, reduced blood flow, inflammation and apoptosis as well as the reduced motility. |
2021-05-14 |
2023-08-13 |
human |
| Bin Chen, Wanqing Lin, Wan Qi, Shibin Li, Zhenfeng Hong, Hongjia Zha. Cofilin Inhibition by Limk1 Reduces Rod Formation and Cell Apoptosis after Ischemic Stroke. Neuroscience. vol 444. 2021-05-14. PMID:32697981. |
cofilin inhibition by limk1 reduces rod formation and cell apoptosis after ischemic stroke. |
2021-05-14 |
2023-08-13 |
rat |
| Bin Chen, Wanqing Lin, Wan Qi, Shibin Li, Zhenfeng Hong, Hongjia Zha. Cofilin Inhibition by Limk1 Reduces Rod Formation and Cell Apoptosis after Ischemic Stroke. Neuroscience. vol 444. 2021-05-14. PMID:32697981. |
from this evidence we conclude that cofilin plays a role in the onset of ischemic-induced apoptosis and may be efficacious in future studies as a drug target for ischemic stroke. |
2021-05-14 |
2023-08-13 |
rat |
| Xiao-Hong Lin, Xiu-Juan Ye, Qing-Feng Li, Zhuo Gong, Xin Cao, Jian-Hua Li, Shen-Ting Zhao, Xiang-Dong Sun, Xiao-Song He, Ai-Guo Xua. Urolithin A Prevents Focal Cerebral Ischemic Injury via Attenuating Apoptosis and Neuroinflammation in Mice. Neuroscience. vol 448. 2021-05-14. PMID:32946950. |
our findings reveal a key role of ua against ischemic stroke through modulating apoptosis and neuroinflammation in mice. |
2021-05-14 |
2023-08-13 |
mouse |
| Jing Xu, Chunyang Wang, Fanjie Meng, Pengjuan X. Long non‑coding RNA H19 inhibition ameliorates oxygen‑glucose deprivation‑induced cell apoptosis and inflammatory cytokine expression by regulating the microRNA‑29b/SIRT1/PGC‑1α axis. Molecular medicine reports. vol 23. issue 2. 2021-05-14. PMID:33313940. |
collectively, the results of the present study demonstrated that lncrna h19 knockdown ameliorated ogd‑induced cell apoptosis and increases in inflammatory cytokine concentrations by regulating mir‑29b, sirt1 and pgc‑1α expression levels, which suggested the potential role of lncrna h19 in ischemic stroke. |
2021-05-14 |
2023-08-13 |
mouse |
| Weijie Xie, Ting Zhu, Ping Zhou, Huibo Xu, Xiangbao Meng, Tao Ding, Fengwei Nan, Guibo Sun, Xiaobo Su. Notoginseng Leaf Triterpenes Ameliorates OGD/R-Induced Neuronal Injury via SIRT1/2/3-Foxo3a-MnSOD/PGC-1 Oxidative medicine and cellular longevity. vol 2020. 2021-05-13. PMID:33149812. |
notoginseng leaf triterpenes ameliorates ogd/r-induced neuronal injury via sirt1/2/3-foxo3a-mnsod/pgc-1 cerebral ischemic stroke (cis) is a common cerebrovascular disease whose main risks include necrosis, apoptosis, and cerebral infarction. |
2021-05-13 |
2023-08-13 |
Not clear |
| Yangtian Yan, Li Chen, Jiajun Zhou, Liquan Xi. SNHG12 inhibits oxygen‑glucose deprivation‑induced neuronal apoptosis via the miR‑181a‑5p/NEGR1 axis. Molecular medicine reports. vol 22. issue 5. 2021-05-03. PMID:33000228. |
neuronal apoptosis aggravates brain damage during ischemic stroke, indicating that the activation of snhg12 and negr1 expression and inhibition of mir‑181a‑5p may be a novel strategy for the clinical treatment of ischemic stroke. |
2021-05-03 |
2023-08-13 |
Not clear |