| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Flavia Antonucci, Angelo Di Garbo, Elena Novelli, Ilaria Manno, Ferdinando Sartucci, Yuri Bozzi, Matteo Cale. Botulinum neurotoxin E (BoNT/E) reduces CA1 neuron loss and granule cell dispersion, with no effects on chronic seizures, in a mouse model of temporal lobe epilepsy. Experimental neurology. vol 210. issue 2. 2008-06-20. PMID:18177862. |
mesial temporal lobe epilepsy (mtle) is often the result of an early insult that induces a reorganization in hippocampal circuitry leading, after a latent period, to chronic epilepsy. |
2008-06-20 |
2023-08-12 |
mouse |
| Flavia Antonucci, Angelo Di Garbo, Elena Novelli, Ilaria Manno, Ferdinando Sartucci, Yuri Bozzi, Matteo Cale. Botulinum neurotoxin E (BoNT/E) reduces CA1 neuron loss and granule cell dispersion, with no effects on chronic seizures, in a mouse model of temporal lobe epilepsy. Experimental neurology. vol 210. issue 2. 2008-06-20. PMID:18177862. |
hippocampal rearrangements during the latent phase include neuronal loss, axonal and dendritic plasticity, neurogenesis, and cell repositioning, but the role of these changes in epilepsy development is unclear. |
2008-06-20 |
2023-08-12 |
mouse |
| Anna Paciorek, Andrzej Urbanik, Jacek Paciorek, Robert Chrzan, Stanisław Sztuk, Anna Zajac, Sławomir Kroczk. [The role of the magnetic resonance spectroscopy in the diagnosis of temporal lobe epilepsy]. Przeglad lekarski. vol 64. issue 11. 2008-06-05. PMID:18409412. |
in persons with epilepsy hmrs of the hippocampus may show the changes in specific metabolites. |
2008-06-05 |
2023-08-12 |
Not clear |
| Gustavo Rassier Isolan, Ney Azambuja, Eliseu Paglioli Neto, Eduardo Pagliol. [Hippocampal microsurgical anatomy regarding the selective amygdalohippocampectomy in the Niemeyer's technique perspective and preoperative method to maximize the corticotomy]. Arquivos de neuro-psiquiatria. vol 65. issue 4A. 2008-06-02. PMID:18094878. |
the deep knowledge of hippocampal microsurgical anatomy is paramount in epilepsy surgery. |
2008-06-02 |
2023-08-12 |
Not clear |
| Dragan Bajic, Chen Wang, Eva Kumlien, Peter Mattsson, Staffan Lundberg, Orvar Eeg-Olofsson, Raili Rainink. Incomplete inversion of the hippocampus--a common developmental anomaly. European radiology. vol 18. issue 1. 2008-05-13. PMID:17828540. |
incomplete inversion of the hippocampus, an imperfect fetal development, has been described in patients with epilepsy or severe midline malformations. |
2008-05-13 |
2023-08-12 |
human |
| Karel Deblaere, Eric Achte. Structural magnetic resonance imaging in epilepsy. European radiology. vol 18. issue 1. 2008-05-13. PMID:17899110. |
imaging focus will be on the diagnosis of hippocampal sclerosis and malformations of cortical development, two major causes of medically intractable focal epilepsy. |
2008-05-13 |
2023-08-12 |
Not clear |
| David C Henshall, Brona M Murph. Modulators of neuronal cell death in epilepsy. Current opinion in pharmacology. vol 8. issue 1. 2008-05-06. PMID:17827063. |
differing hippocampal expression of certain bcl-2 family genes, elevated endoplasmic reticulum stress chaperones, and death receptor pathway modulation in epilepsy patients support clinical relevance of this focus. |
2008-05-06 |
2023-08-12 |
mouse |
| Qin Wang, Dong Zhou, Bo Yan, Xu Lin, Shang-fu Zhan. [Expression of Merlin in cortex of temporal lobe and in hippocampal CA1 region of the Kindling Model of Epilepsy induced by corciaria lactone in rats]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. vol 37. issue 1. 2008-04-21. PMID:16468657. |
to explore the relationship between merlin and hippocampal sclerosis of temporal epilepsy. |
2008-04-21 |
2023-08-12 |
rat |
| Feng Guo, Na Yu, Ji-Qun Cai, Tim Quinn, Zhi-Hong Zong, Yan-Jun Zeng, Li-Ying Ha. Voltage-gated sodium channel Nav1.1, Nav1.3 and beta1 subunit were up-regulated in the hippocampus of spontaneously epileptic rat. Brain research bulletin. vol 75. issue 1. 2008-04-11. PMID:18158113. |
the results of this study may be of value in revealing components of the molecular mechanisms of hippocampal excitation that are related to genetic epilepsy. |
2008-04-11 |
2023-08-12 |
human |
| A D Wickenden, J L Krajewski, B London, P K Wagoner, W A Wilson, S Clark, R Roeloffs, G McNaughton-Smith, G C Rigdo. N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide (ICA-27243): a novel, selective KCNQ2/Q3 potassium channel activator. Molecular pharmacology. vol 73. issue 3. 2008-04-07. PMID:18089837. |
ica-27243 (1-10 microm) was found to reversibly suppress seizure-like activity in an ex vivo hippocampal slice model of epilepsy and demonstrated in vivo anticonvulsant activity (ed(50) = 8.4 mg/kg) in the mouse maximal electroshock epilepsy model. |
2008-04-07 |
2023-08-12 |
mouse |
| Maurizio Cavallaro, Jessica Mariani, Cesare Lancini, Elisa Latorre, Roberta Caccia, Francesca Gullo, Menella Valotta, Silvia DeBiasi, Laura Spinardi, Antonella Ronchi, Enzo Wanke, Silvia Brunelli, Rebecca Favaro, Sergio Ottolenghi, Silvia K Nicoli. Impaired generation of mature neurons by neural stem cells from hypomorphic Sox2 mutants. Development (Cambridge, England). vol 135. issue 3. 2008-04-07. PMID:18171687. |
in humans, heterozygous sox2 deficiency is associated with eye abnormalities, hippocampal malformation and epilepsy. |
2008-04-07 |
2023-08-12 |
mouse |
| Cristina Richichi, Amy L Brewster, Roland A Bender, Timothy A Simeone, Qinqin Zha, Hong Z Yin, John H Weiss, Tallie Z Bara. Mechanisms of seizure-induced 'transcriptional channelopathy' of hyperpolarization-activated cyclic nucleotide gated (HCN) channels. Neurobiology of disease. vol 29. issue 2. 2008-04-04. PMID:17964174. |
altered expression levels of the hcn channels - that conduct the hyperpolarization-activated current, i(h) - have been demonstrated in hippocampus of patients with severe temporal lobe epilepsy as well as in animal models of temporal lobe and absence epilepsies. |
2008-04-04 |
2023-08-12 |
Not clear |
| J A Silva, E M Goto, S R Perosa, G A Argañaraz, E A Cavalheiro, M G Naffah-Mazzacoratti, J B Pesquer. Kinin B1 receptors facilitate the development of temporal lobe epilepsy in mice. International immunopharmacology. vol 8. issue 2. 2008-04-03. PMID:18182226. |
in the present study, we evaluated the hippocampal expression of the remaining kinin receptor in b1 (b1ko) and b2 (b2ko) knockout mice strains during the development of pilocarpine epilepsy model. |
2008-04-03 |
2023-08-12 |
mouse |
| P A Williams, F E Dude. A chronic histopathological and electrophysiological analysis of a rodent hypoxic-ischemic brain injury model and its use as a model of epilepsy. Neuroscience. vol 149. issue 4. 2008-03-28. PMID:17935893. |
recent studies have shown that an h-i injury in perinatal rats causes hippocampal mossy fiber sprouting and epilepsy. |
2008-03-28 |
2023-08-12 |
rat |
| Jennifer D Simonotto, Stephen M Myers, Michael D Furman, Wendy M Norman, Zhao Liu, Thomas B DeMarse, Paul R Carney, William L Ditt. Coherence analysis over the latent period of epileptogenesis reveal that high-frequency communication is increased across hemispheres in an animal model of limbic epilepsy. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. vol 2006. 2008-03-19. PMID:17946026. |
a total of 32 microwire electrodes were implanted bilaterally into the hippocampus of sprague-dawley rats, which were then stimulated in the manner prescribed for the chronic limbic epilepsy model. |
2008-03-19 |
2023-08-12 |
rat |
| Mitushi Mishra, Britta Jones, Jennifer D Simonotto, Michael D Furman, Wendy M Norman, Zhao Liu, Thomas B DeMarse, Paul R Carney, William L Ditt. Pre-ictal entropy analysis of microwire data from an animal model of limbic epilepsy. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. vol 2006. 2008-03-17. PMID:17946055. |
epilepsy is a common neurological disorder that can have damaging effects in the brain including over 50% loss of neuronal activity in the hippocampal regions of the ca1 and ca3. |
2008-03-17 |
2023-08-12 |
Not clear |
| Dominique M Durand, Alicia Jensen, Marom Bikso. Suppression of neural activity with high frequency stimulation. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. vol 2006. 2008-03-17. PMID:17946913. |
sinusoidal stimulation at 50 hz applied to the ca1 region of the hippocampus was observed to block epileptiform activity in three separate models of epilepsy induced by low-calcium, high potassium and picrotoxin (gaba a blocker). |
2008-03-17 |
2023-08-12 |
Not clear |
| Thomas P Sutula, F Edward Dude. Unmasking recurrent excitation generated by mossy fiber sprouting in the epileptic dentate gyrus: an emergent property of a complex system. Progress in brain research. vol 163. 2008-03-14. PMID:17765737. |
seizure-induced sprouting of the mossy fiber pathway in the dentate gyrus has been observed nearly universally in experimental models of limbic epilepsy and in the epileptic human hippocampus. |
2008-03-14 |
2023-08-12 |
human |
| Thomas P Sutula, F Edward Dude. Unmasking recurrent excitation generated by mossy fiber sprouting in the epileptic dentate gyrus: an emergent property of a complex system. Progress in brain research. vol 163. 2008-03-14. PMID:17765737. |
the recognition that mossy fiber sprouting is induced after hippocampal injury and seizures and contributes conditionally to emergence of recurrent excitation has provided a conceptual framework for understanding how injury and seizure-induced circuit reorganization may contribute to paroxysmal network synchronization, epileptogenesis, and the consequences of repeated seizures, and thus has had a major influence on understanding of fundamental aspects of the epilepsies. |
2008-03-14 |
2023-08-12 |
human |
| Joseph N Y Aziz, Rafal Karakiewicz, Roman Genov, Berj L Bardakjian, Miron Derchansky, Peter L Carle. Towards real-time in-implant epileptic seizure prediction. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. vol 2006. 2008-03-10. PMID:17947144. |
the wavelet-based artificial neural network predicts the onsets of seizure up to two minutes before their occurrence in an in-vitro epilepsy model using a mouse hippocampal brain slice with recurrent spontaneous seizures. |
2008-03-10 |
2023-08-12 |
mouse |