| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pedro Belez. Refractory epilepsy: a clinically oriented review. European neurology. vol 62. issue 2. 2009-09-22. PMID:19521080. |
risk factors for refractoriness include (1) generalized epilepsy with lesions; (2) focal epilepsy with hippocampal sclerosis, cortical dysplasia or hemorrhages; (3) early epilepsy onset; (4) high seizure frequency; (5) absence of response to the first 2 aeds; (6) high frequency of interictal spikes, and (7) multifocal spikes. |
2009-09-22 |
2023-08-12 |
Not clear |
| S-E Kwak, J-E Kim, D-W Kim, O-S Kwon, S-Y Choi, T-C Kan. Enhanced pyridoxal 5'-phosphate synthetic enzyme immunoreactivities do not contribute to GABAergic inhibition in the rat hippocampus following pilocarpine-induced status epilepticus. Neuroscience. vol 159. issue 3. 2009-09-21. PMID:19356691. |
to comprehend the role of pyridoxal 5'-phosphate (plp) in epilepsy or seizure, we investigated whether the expressions of two plp synthetic enzymes (pyridoxal kinase, plk; pyridoxine-5'-phosphate oxidase, pnpo) are altered in the hippocampus and whether changes in paired-pulse responses in the hippocampus are associated with altered plp synthetic enzyme expressions following status epilepticus (se). |
2009-09-21 |
2023-08-12 |
rat |
| César Renato Sartori, Fernanda Campos Pelágio, Simone Aparecida Teixeira, Verónica Sandra Valentinuzzi, André Luiz Nascimento, Fábio Rogério, Marcelo Nicolás Muscará, Elenice Aparecida de Moraes Ferrari, Francesco Langon. Effects of voluntary running on spatial memory and mature brain-derived neurotrophic factor expression in mice hippocampus after status epilepticus. Behavioural brain research. vol 203. issue 2. 2009-09-10. PMID:19397936. |
physical activity and seizures have been associated with enhanced hippocampal expression of bdnf, indicating that this protein may have a dual role in epilepsy. |
2009-09-10 |
2023-08-12 |
mouse |
| Yasuhiro Yonekaw. [On the occasion of my retirement as head of the Neurochirurgische Universitätsklinik Zürich--part II--presentation of our achievement with mention of development of neuroscience in Zürich-Switzerland]. Brain and nerve = Shinkei kenkyu no shinpo. vol 61. issue 6. 2009-09-03. PMID:19526834. |
they are consisting of followings (see text literatures in english); gene alteration or mutation in the neoplasm of the central nervous system, particularly glioma (with dr. ohgaki, prof. kleihues of iarc), gabaa receptor subunit of hippocampus in temporal lobe epilepsy (with dr. loup prof. fritschy, pharmacology, uzh), role of apoptosis in the treatment of glioblastoma using taurolin (prof. frei, pharmacology, uzh), neurointensive medicine (pd dr. keller with prof. nadler, eth), epilepsy surgery, particularly by selective amygdalohippocampectomy (sahe), which was pioneered in zürich (with prof. wieser, neurology). |
2009-09-03 |
2023-08-12 |
Not clear |
| Asta Kastanauskaite, Lidia Alonso-Nanclares, Lidia Blazquez-Llorca, Jesus Pastor, Rafael G Sola, Javier DeFelip. Alterations of the microvascular network in sclerotic hippocampi from patients with epilepsy. Journal of neuropathology and experimental neurology. vol 68. issue 8. 2009-09-01. PMID:19606060. |
to determine whether the reduction in alkaline phosphatase activity is coupled with a loss of blood vessels,we examined the volume fraction occupied by blood vessels in toluidine blue-stained hippocampal sections from 24 epilepsy patient resections (19 with hippocampal sclerosis, 5 without hippocampal sclerosis) and 5 normal autopsy controls. |
2009-09-01 |
2023-08-12 |
human |
| Xuqin Chen, Guanshui Bao, Ying Hua, Yan Li, Zhedong Wang, Xueguang Zhan. The effects of topiramate on caspase-3 expression in hippocampus of basolateral amygdala (BLA) electrical kindled epilepsy rat. Journal of molecular neuroscience : MN. vol 38. issue 2. 2009-08-31. PMID:19148780. |
the effects of topiramate on caspase-3 expression in hippocampus of basolateral amygdala (bla) electrical kindled epilepsy rat. |
2009-08-31 |
2023-08-12 |
rat |
| Jan Tønnesen, Andreas T Sørensen, Karl Deisseroth, Cecilia Lundberg, Merab Kokai. Optogenetic control of epileptiform activity. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 29. 2009-08-25. PMID:19581573. |
this study proves a principle, that selective hyperpolarization of principal cortical neurons by nphr is sufficient to curtail paroxysmal activity in transduced neurons and can inhibit stimulation train-induced bursting in hippocampal organotypic slice cultures, which represents a model tissue of pharmacoresistant epilepsy. |
2009-08-25 |
2023-08-12 |
Not clear |
| Yong-Hong Liu, Lian Wang, Li-Chun Wei, Yuan-Gui Huang, Liang-Wei Che. Up-regulation of D-serine might induce GABAergic neuronal degeneration in the cerebral cortex and hippocampus in the mouse pilocarpine model of epilepsy. Neurochemical research. vol 34. issue 7. 2009-08-10. PMID:19123037. |
up-regulation of d-serine might induce gabaergic neuronal degeneration in the cerebral cortex and hippocampus in the mouse pilocarpine model of epilepsy. |
2009-08-10 |
2023-08-12 |
mouse |
| Luciana D'Alessio, Brenda Giagante, Cristina Papayannis, Silvia Oddo, Walter Silva, Patricia Solís, Vicente Donnoli, Marcelo Kauffman, Damián Consalvo, Luis María Zieher, Silvia Koche. Psychotic disorders in Argentine patients with refractory temporal lobe epilepsy: a case-control study. Epilepsy & behavior : E&B. vol 14. issue 4. 2009-08-07. PMID:19236954. |
risk factors for psychotic disorders were bilateral hippocampal sclerosis, history of status epilepticus, and duration of epilepsy greater than 20 years. |
2009-08-07 |
2023-08-12 |
Not clear |
| Friedrich G Woermann, Christian Vollma. Clinical MRI in children and adults with focal epilepsy: a critical review. Epilepsy & behavior : E&B. vol 15. issue 1. 2009-07-27. PMID:19236945. |
hippocampal sclerosis in adults and focal cortical dysplasia in children with epilepsy are frequent lesions, but they are overlooked on standard mri. |
2009-07-27 |
2023-08-12 |
Not clear |
| Marta García-Fiñana, Simon S Keller, Neil Robert. Confidence intervals for the volume of brain structures in Cavalieri sampling with local errors. Journal of neuroscience methods. vol 179. issue 1. 2009-07-16. PMID:19428514. |
finally, the new approach is applied to investigate the significance of hippocampus volume change in a patient with epilepsy after 2 years of disease. |
2009-07-16 |
2023-08-12 |
Not clear |
| Friederike Kienzler, Braxton A Norwood, Robert S Slovite. Hippocampal injury, atrophy, synaptic reorganization, and epileptogenesis after perforant pathway stimulation-induced status epilepticus in the mouse. The Journal of comparative neurology. vol 515. issue 2. 2009-07-15. PMID:19412934. |
prolonged dentate granule cell discharges produce hippocampal injury and chronic epilepsy in rats. |
2009-07-15 |
2023-08-12 |
mouse |
| K L I van Gassen, W S van der Hel, T B M Hakvoort, W H Lamers, P N E de Graa. Haploinsufficiency of glutamine synthetase increases susceptibility to experimental febrile seizures. Genes, brain, and behavior. vol 8. issue 3. 2009-07-14. PMID:19170755. |
gs is important in maintaining low extracellular glutamate concentrations and is downregulated in the hippocampus of temporal lobe epilepsy patients with mesial-temporal sclerosis, an epilepsy syndrome that is frequently associated with early life febrile seizures (fs). |
2009-07-14 |
2023-08-12 |
mouse |
| E V Isaev. Mechanism of antiseizure effect of isoflurane in the immature rat hippocampus. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 55. issue 1. 2009-07-14. PMID:19441716. |
in this study we explore the role of excitatory and inhibitory conductances in antiseizure effect of isoflurane using combination of whole-cell patch-clamp and extracellular field potential recording techniques on two models of epilepsy in a hippocampal slice preparation from immature rat. |
2009-07-14 |
2023-08-12 |
rat |
| M Chupin, A Hammers, R S N Liu, O Colliot, J Burdett, E Bardinet, J S Duncan, L Garnero, L Lemieu. Automatic segmentation of the hippocampus and the amygdala driven by hybrid constraints: method and validation. NeuroImage. vol 46. issue 3. 2009-06-24. PMID:19236922. |
quantitative evaluation with respect to manual segmentations was performed on the 16 young subjects, with a leave-one-out strategy, a mixed cohort of 8 controls and 15 patients with epilepsy with variable degrees of hippocampal sclerosis, and 8 healthy subjects acquired on a 3 t scanner. |
2009-06-24 |
2023-08-12 |
human |
| Jan-Christoph Schoene-Bake, Jennifer Faber, Peter Trautner, Sabine Kaaden, Marc Tittgemeyer, Christian E Elger, Bernd Webe. Widespread affections of large fiber tracts in postoperative temporal lobe epilepsy. NeuroImage. vol 46. issue 3. 2009-06-24. PMID:19289170. |
temporal lobe epilepsy with hippocampus sclerosis (hs) is the most frequent focal epilepsy and often refractory to anticonvulsant therapy. |
2009-06-24 |
2023-08-12 |
Not clear |
| Sadat Shamim, Gregor Hasler, Clarissa Liew, Susumu Sato, William H Theodor. Temporal lobe epilepsy, depression, and hippocampal volume. Epilepsia. vol 50. issue 5. 2009-06-22. PMID:19054394. |
to evaluate the relationship between hippocampal volume loss, depression, and epilepsy. |
2009-06-22 |
2023-08-12 |
Not clear |
| Flavia Doná, Henning Ulrich, Daniele Suzete Persike, Isaltino Marcelo Conceição, João Paulo Blini, Esper Abrão Cavalheiro, Maria José Silva Fernande. Alteration of purinergic P2X4 and P2X7 receptor expression in rats with temporal-lobe epilepsy induced by pilocarpine. Epilepsy research. vol 83. issue 2-3. 2009-06-22. PMID:19084381. |
temporal-lobe epilepsy (tle) in rat was induced by pilocarpine in order to study changes of hippocampal p2x(2), p2x(4) and p2x(7) receptor expression during acute, latent or chronic phases of epilepsy. |
2009-06-22 |
2023-08-12 |
rat |
| Flavia Doná, Henning Ulrich, Daniele Suzete Persike, Isaltino Marcelo Conceição, João Paulo Blini, Esper Abrão Cavalheiro, Maria José Silva Fernande. Alteration of purinergic P2X4 and P2X7 receptor expression in rats with temporal-lobe epilepsy induced by pilocarpine. Epilepsy research. vol 83. issue 2-3. 2009-06-22. PMID:19084381. |
no significant alterations of hippocampal p2x(2) and p2x(4) receptor expression was noted during the acute or latent phase when compared to the control group, indicating that these receptors are not directly involved with the initiation of epilepsy. |
2009-06-22 |
2023-08-12 |
rat |
| T V Pavlova, M Iu Stepanichev, A B Gekht, N V Guliaev. [Active avoidance learning in rats and morphological changes in the hippocampus after pentylenetetrazole kindling]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 59. issue 2. 2009-06-19. PMID:19445390. |
the relationship between parameters of active avoidance conditioning and morphological changes in the hippocampus was investigated using pentylenetetrazole kindling animal model of epilepsy. |
2009-06-19 |
2023-08-12 |
rat |