| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Soraya Martín-Suárez, Oihane Abiega, Ana Ricobaraza, Rubén Hernandez-Alcoceba, Juan Manuel Encina. Alterations of the Hippocampal Neurogenic Niche in a Mouse Model of Dravet Syndrome. Frontiers in cell and developmental biology. vol 8. 2020-09-28. PMID:32793597. |
we here analyze for the first time the alterations of the neurogenic niche in a novel mouse model of dravet syndrome (ds), a genetic encephalopathy with severe epilepsy in infancy and multiple neurological comorbidities. |
2020-09-28 |
2023-08-13 |
mouse |
| Daniel J Kats, Katherine J Roche, Brian G Skotk. Epileptic spasms in individuals with Down syndrome: A review of the current literature. Epilepsia open. vol 5. issue 3. 2020-09-28. PMID:32913943. |
epilepsy can occur in individuals with down syndrome (ds), with epileptic spasms representing the most frequent seizure type in this population. |
2020-09-28 |
2023-08-13 |
Not clear |
| Daniel J Kats, Katherine J Roche, Brian G Skotk. Epileptic spasms in individuals with Down syndrome: A review of the current literature. Epilepsia open. vol 5. issue 3. 2020-09-28. PMID:32913943. |
according to available literature, the global clinic-based lifetime prevalence of epilepsy in individuals with ds ranged from 1.6% to 23.1%, with epileptic spasms representing 6.7%-66.7% of these cases. |
2020-09-28 |
2023-08-13 |
Not clear |
| Daniel J Kats, Katherine J Roche, Brian G Skotk. Epileptic spasms in individuals with Down syndrome: A review of the current literature. Epilepsia open. vol 5. issue 3. 2020-09-28. PMID:32913943. |
generally, children with ds and epileptic spasms tend to be more responsive to treatment and have better outcomes than children with epileptic spasms of unknown etiology (ie, without ds), in terms of response and relapse rates as well as the development of intractable epilepsy (eg, lennox-gastaut syndrome). |
2020-09-28 |
2023-08-13 |
Not clear |
| Jens Schuster, Loora Laan, Joakim Klar, Zhe Jin, Mikael Huss, Sergiy Korol, Feria Hikmet Noraddin, Maria Sobol, Bryndis Birnir, Niklas Dah. Transcriptomes of Dravet syndrome iPSC derived GABAergic cells reveal dysregulated pathways for chromatin remodeling and neurodevelopment. Neurobiology of disease. vol 132. 2020-08-06. PMID:31445158. |
dravet syndrome (ds) is an early onset refractory epilepsy typically caused by de novo heterozygous variants in scn1a encoding the α-subunit of the neuronal sodium channel na |
2020-08-06 |
2023-08-13 |
Not clear |
| Christine S Cheah, Brian N Lundstrom, William A Catterall, John C Oakle. Impairment of Sharp-Wave Ripples in a Murine Model of Dravet Syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 46. 2020-06-30. PMID:31537705. |
dravet syndrome (ds) is a severe early-onset epilepsy associated with heterozygous loss-of-function mutations in |
2020-06-30 |
2023-08-13 |
Not clear |
| Masaya Katagiri, Koji Iida, Kumatoshi Ishihara, Dileep Nair, Kana Harada, Kota Kagawa, Go Seyama, Akira Hashizume, Takashi Kuramoto, Ryosuke Hanaya, Kazunori Arita, Kaoru Kuris. Anti-seizure effect and neuronal activity change in the genetic-epileptic model rat with acute and chronic vagus nerve stimulation. Epilepsy research. vol 155. 2020-05-26. PMID:31277035. |
noda epileptic rat (ner) is genetic epilepsy model rat which exhibits spontaneous generalized tonic-clonic seizure (gtc) approximately once per 30 h and frequent dialeptic seizure (ds). |
2020-05-26 |
2023-08-13 |
rat |
| Sara K Trowbridge, Christopher J Yuskaitis, Nicole Baumer, Mark Libenson, Sanjay P Prabhu, Chellamani Harin. Brain MRI abnormalities in patients with infantile spasms and Down syndrome. Epilepsy & behavior : E&B. vol 92. 2020-05-25. PMID:30616066. |
infantile spasms (is) are the most frequent epilepsy syndrome in children with down syndrome (ds). |
2020-05-25 |
2023-08-13 |
Not clear |
| Raymond E A Sanchez, Ivana L Bussi, Miriam Ben-Hamo, Carlos S Caldart, William A Catterall, Horacio O De La Iglesi. Circadian regulation of sleep in a pre-clinical model of Dravet syndrome: dynamics of sleep stage and siesta re-entrainment. Sleep. vol 42. issue 12. 2020-05-11. PMID:31346614. |
dravet syndrome (ds) is an intractable epilepsy accompanied by disturbed sleep. |
2020-05-11 |
2023-08-13 |
mouse |
| Jens Schuster, Ambrin Fatima, Maria Sobol, Feria Hikmet Norradin, Loora Laan, Niklas Dah. Generation of three human induced pluripotent stem cell (iPSC) lines from three patients with Dravet syndrome carrying distinct SCN1A gene mutations. Stem cell research. vol 39. 2020-04-27. PMID:31400703. |
dravet syndrome (ds) is a childhood epilepsy syndrome caused by heterozygous mutations in the scn1a gene encoding voltage-gated sodium channel na |
2020-04-27 |
2023-08-13 |
human |
| Francesca Darra, Domenica Battaglia, Charlotte Dravet, Mara Patrini, Francesca Offredi, Daniela Chieffo, Elena Piazza, Elena Fontana, Giorgia Olivieri, Ida Turrini, Bernardo Dalla Bernardina, Tiziana Granata, Francesca Ragon. Dravet syndrome: Early electroclinical findings and long-term outcome in adolescents and adults. Epilepsia. vol 60 Suppl 3. 2020-04-23. PMID:31904122. |
the study confirms that the global outcome of ds is poor in most cases, albeit epilepsy severity decreases throughout adulthood. |
2020-04-23 |
2023-08-13 |
Not clear |
| Adam Strzelczyk, Susanne Schubert-Bast, Thomas Bast, Ulrich Bettendorf, Barbara Fiedler, Hajo M Hamer, Arne Herting, Malin Kalski, Lara Kay, Matthias Kieslich, Karl Martin Klein, Gerhard Kluger, Gerhard Kurlemann, Thomas Mayer, Bernd A Neubauer, Tilman Polster, Sarah von Spiczak, Ulrich Stephani, Regina Trollmann, Adelheid Wiemer-Kruel, Markus Wolff, John Irwin, Joe Carroll, Clive Pritchard, Felix Roseno. A multicenter, matched case-control analysis comparing burden-of-illness in Dravet syndrome to refractory epilepsy and seizure remission in patients and caregivers in Germany. Epilepsia. vol 60. issue 8. 2020-04-15. PMID:31247127. |
to compare direct and indirect costs and quality of life (qol) of pediatric and adult patients with dravet syndrome (ds), with drug-resistant epilepsy (dre) and in seizure remission (sr), and their caregivers, in germany. |
2020-04-15 |
2023-08-13 |
Not clear |
| Fu-Shan Kuo, Colin M Cleary, Joseph J LoTurco, Xinnian Chen, Daniel K Mulke. Disordered breathing in a mouse model of Dravet syndrome. eLife. vol 8. 2020-02-24. PMID:31025941. |
dravet syndrome (ds) is a form of epilepsy with a high incidence of sudden unexpected death in epilepsy (sudep). |
2020-02-24 |
2023-08-13 |
mouse |
| Naohiro Ohshita, Kaname Tsuji, Hiroaki Yoshida, Hiroki Shibata, Yoshiko Matsuda, Yasuo M Tsutsumi, Yoshihiro Momot. Anesthetic Management of Patient With Dravet Syndrome: A Case Report. Anesthesia progress. vol 66. issue 3. 2020-02-17. PMID:31545672. |
dravet syndrome (ds) is a rare and severe form of epilepsy that begins in infancy. |
2020-02-17 |
2023-08-13 |
Not clear |
| Zhigang Liu, Xingguang Ye, Peixiu Qiao, Weiyao Luo, Yanling Wu, Yun He, Pingming Ga. G327E mutation in SCN9A gene causes idiopathic focal epilepsy with Rolandic spikes: a case report of twin sisters. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 40. issue 7. 2020-01-13. PMID:30834459. |
phenotypes of scn9a mutations include febrile seizures (fs), genetic epilepsy with febrile seizures plus (gefs+), and dravet syndrome (ds), which pose challenges in clinical treatment. |
2020-01-13 |
2023-08-13 |
Not clear |
| M M Rahman, K Fatem. Seizures in Down Syndrome: An Update. Mymensingh medical journal : MMJ. vol 28. issue 3. 2019-10-21. PMID:31391451. |
rates of epilepsy in ds range from 1-13%. |
2019-10-21 |
2023-08-13 |
Not clear |
| M M Rahman, K Fatem. Seizures in Down Syndrome: An Update. Mymensingh medical journal : MMJ. vol 28. issue 3. 2019-10-21. PMID:31391451. |
sex distribution for epilepsy in children with ds varies. |
2019-10-21 |
2023-08-13 |
Not clear |
| M M Rahman, K Fatem. Seizures in Down Syndrome: An Update. Mymensingh medical journal : MMJ. vol 28. issue 3. 2019-10-21. PMID:31391451. |
the pharmacological treatment of epilepsy in ds is same as that of other patients diagnosed with epilepsy. |
2019-10-21 |
2023-08-13 |
Not clear |
| M M Rahman, K Fatem. Seizures in Down Syndrome: An Update. Mymensingh medical journal : MMJ. vol 28. issue 3. 2019-10-21. PMID:31391451. |
the diagnosis, classification and treatment of epilepsy in ds follow the guidelines applied to the general population. |
2019-10-21 |
2023-08-13 |
Not clear |
| M M Rahman, K Fatem. Seizures in Down Syndrome: An Update. Mymensingh medical journal : MMJ. vol 28. issue 3. 2019-10-21. PMID:31391451. |
review of literatures from 1960 to 2017 and electronically identified articles on epilepsy in down syndrome in children in english are searched from internet and pub med to describe features of seizures in children with ds. |
2019-10-21 |
2023-08-13 |
Not clear |