| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jo Sourbron, Henning Schneider, Angéla Kecskés, Yusu Liu, Ellen M Buening, Lieven Lagae, Ilse Smolders, Peter de Witt. Serotonergic Modulation as Effective Treatment for Dravet Syndrome in a Zebrafish Mutant Model. ACS chemical neuroscience. vol 7. issue 5. 2017-01-27. PMID:26822114. |
dravet syndrome (ds) is a severe epilepsy syndrome that starts within the first year of life. |
2017-01-27 |
2023-08-13 |
human |
| Adam Wallace, Elaine Wirrell, Daniel L Kenney-Jun. Pharmacotherapy for Dravet Syndrome. Paediatric drugs. vol 18. issue 3. 2016-12-13. PMID:26966048. |
dravet syndrome (ds) is an intractable pediatric epilepsy syndrome, starting in early childhood. |
2016-12-13 |
2023-08-13 |
Not clear |
| Maneesh G Kumar, Shane Rowley, Ruth Fulton, Matthew T Dinday, Scott C Baraban, Manisha Pate. Altered Glycolysis and Mitochondrial Respiration in a Zebrafish Model of Dravet Syndrome. eNeuro. vol 3. issue 2. 2016-12-13. PMID:27066534. |
altered metabolism is an important feature of many epileptic syndromes but has not been reported in dravet syndrome (ds), a catastrophic childhood epilepsy associated with mutations in a voltage-activated sodium channel, nav1.1 (scn1a). |
2016-12-13 |
2023-08-13 |
zebrafish |
| Milan Surovy, Andrea Soltysova, Miriam Kolnikova, Pavol Sykora, Denisa Ilencikova, Andrej Ficek, Jan Radvanszky, Ludevit Kadas. Novel SCN1A variants in Dravet syndrome and evaluating a wide approach of patient selection. General physiology and biophysics. vol 35. issue 3. 2016-09-13. PMID:27045673. |
causative variants in scn1a gene which codes the main, pore-forming subunit of the channel expressed in central nervous system are associated predominantly with dravet syndrome (ds), as well as with generalized epilepsy with febrile seizures plus (gefs+) making it one of the most significant epilepsy gene. |
2016-09-13 |
2023-08-13 |
Not clear |
| Marisse Meeus, Sandra Kenis, Marek Wojciechowski, Berten Ceuleman. Epilepsy in children with Down syndrome: not so benign as generally accepted. Acta neurologica Belgica. vol 115. issue 4. 2016-08-17. PMID:25894349. |
this article summarizes our experience with epilepsy in children with ds, describing the different treatment options that were used. |
2016-08-17 |
2023-08-13 |
Not clear |
| Bruno Henrique Silva Araujo, Laila Brito Torres, Laura Maria F F Guilhot. Cerebal overinhibition could be the basis for the high prevalence of epilepsy in persons with Down syndrome. Epilepsy & behavior : E&B. vol 53. 2016-07-11. PMID:26558714. |
down syndrome (ds) is the most common cause of genetic intellectual disability, and the trisomy 21 is associated with more than 80 clinical traits, including higher risk for epilepsy. |
2016-07-11 |
2023-08-13 |
mouse |
| Bruno Henrique Silva Araujo, Laila Brito Torres, Laura Maria F F Guilhot. Cerebal overinhibition could be the basis for the high prevalence of epilepsy in persons with Down syndrome. Epilepsy & behavior : E&B. vol 53. 2016-07-11. PMID:26558714. |
this review discusses the gabaergic system in the human ds brain and the possible implication of the gabaergic network circuit in the epileptogenic process in individuals where the pathogenetic basis for epilepsy is unknown. |
2016-07-11 |
2023-08-13 |
mouse |
| Chandra Mohan Sharma, Rajendra Kumar Pandey, Banshi Lal Kumawat, Dinesh Khandelwa. Late-onset myoclonic epilepsy in Down syndrome (LOMEDS): A spectrum of progressive myoclonic epilepsy - Case report. Annals of Indian Academy of Neurology. vol 19. issue 2. 2016-06-13. PMID:27293345. |
cognitive decline and epilepsy are well recognized complication of down syndrome (ds). |
2016-06-13 |
2023-08-13 |
Not clear |
| Chandra Mohan Sharma, Rajendra Kumar Pandey, Banshi Lal Kumawat, Dinesh Khandelwa. Late-onset myoclonic epilepsy in Down syndrome (LOMEDS): A spectrum of progressive myoclonic epilepsy - Case report. Annals of Indian Academy of Neurology. vol 19. issue 2. 2016-06-13. PMID:27293345. |
very few cases had been described in literature of late-onset myoclonic epilepsy in ds. |
2016-06-13 |
2023-08-13 |
Not clear |
| Marta Rubio, Sara Valdeolivas, Fabiana Piscitelli, Roberta Verde, Valentina Satta, Eva Barroso, Marisol Montolio, Luis Miguel Aras, Vincenzo Di Marzo, Onintza Sagredo, Javier Fernández-Rui. Analysis of endocannabinoid signaling elements and related proteins in lymphocytes of patients with Dravet syndrome. Pharmacology research & perspectives. vol 4. issue 2. 2016-04-12. PMID:27069631. |
cannabidiol (cbd) reduces seizures in childhood epilepsy syndromes including dravet syndrome (ds). |
2016-04-12 |
2023-08-13 |
Not clear |
| M Hernández, M Pedraza, T Mesa, M Troncos. [Complex febrile Seizures or Dravet syndrome?: Description of 3 case reports]. Revista chilena de pediatria. vol 85. issue 5. 2016-03-28. PMID:25697436. |
dravet syndrome (ds) is one of the most intractable forms of epilepsy that begins in infancy. |
2016-03-28 |
2023-08-13 |
Not clear |
| Christian M Korf. Vaccinations and Dravet Syndrome. Pediatric neurology briefs. vol 29. issue 11. 2016-03-02. PMID:26933542. |
investigators from various university hospitals, reference medical institutions and epilepsy centers, and the national institute for public health and environment in the netherlands, studied the effect of vaccinations on seizure risk and disease course in patients with dravet syndrome (ds). |
2016-03-02 |
2023-08-13 |
Not clear |
| Joana Acha, Alejandro Pérez, Doug J Davidson, Manuel Carreira. Cognitive characterization of children with Dravet syndrome: A neurodevelopmental perspective. Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence. vol 21. issue 5. 2016-02-23. PMID:25270117. |
dravet syndrome (ds) is an epilepsy of infantile onset, usually related to a mutation in gene sodium channel alpha 1 subunit, that leads to different typological seizures before the first year of life. |
2016-02-23 |
2023-08-13 |
Not clear |
| Yifan Zhang, Angéla Kecskés, Daniëlle Copmans, Mélanie Langlois, Alexander D Crawford, Berten Ceulemans, Lieven Lagae, Peter A M de Witte, Camila V Esguerr. Pharmacological characterization of an antisense knockdown zebrafish model of Dravet syndrome: inhibition of epileptic seizures by the serotonin agonist fenfluramine. PloS one. vol 10. issue 5. 2016-02-04. PMID:25965391. |
dravet syndrome (ds) is one of the most pharmacoresistant and devastating forms of childhood epilepsy syndromes. |
2016-02-04 |
2023-08-13 |
mouse |
| b' Nienke E Verbeek, Merel Wassenaar, Jolien S van Campen, Anja Sonsma, Boudewijn Gunning, Nine Knoers, Dick Lindhout, Floor E Jansen, Frans Leijten, Eva H Brilstra, Doroth\\xc3\\xa9e Kasteleijn-Nolst Trenit\\xc3\\xa. Seizure precipitants in Dravet syndrome: What events and activities are specifically provocative compared with other epilepsies? Epilepsy & behavior : E&B. vol 47. 2016-01-25. PMID:26021464.' |
this study aimed to describe seizure precipitants in dravet syndrome (ds) compared with other epilepsies. |
2016-01-25 |
2023-08-13 |
Not clear |
| Ming-Shian Tsai, Meng-Larn Lee, Chun-Yun Chang, Hsiang-Hsuan Fan, I-Shing Yu, You-Tzung Chen, Jhih-Yi You, Chun-Yu Chen, Fang-Chia Chang, Jane H Hsiao, Olga Khorkova, Horng-Huei Liou, Yuchio Yanagawa, Li-Jen Lee, Shu-Wha Li. Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant Dravet Syndrome model during development. Neurobiology of disease. vol 77. 2016-01-06. PMID:25725421. |
dravet syndrome (ds) is characterized by severe infant-onset myoclonic epilepsy along with delayed psychomotor development and heightened premature mortality. |
2016-01-06 |
2023-08-13 |
mouse |
| Franck Kalume, John C Oakley, Ruth E Westenbroek, Jennifer Gile, Horacio O de la Iglesia, Todd Scheuer, William A Catteral. Sleep impairment and reduced interneuron excitability in a mouse model of Dravet Syndrome. Neurobiology of disease. vol 77. 2016-01-06. PMID:25766678. |
although sleep disorders in epilepsies have been attributed to anti-epileptic drugs, our results show that sleep disorder in ds mice arises from loss of nav1.1 channels in forebrain gabaergic interneurons without drug treatment. |
2016-01-06 |
2023-08-13 |
mouse |
| Stacey B Dutton, Christopher D Makinson, Ligia A Papale, Anupama Shankar, Bindu Balakrishnan, Kazu Nakazawa, Andrew Escay. Preferential inactivation of Scn1a in parvalbumin interneurons increases seizure susceptibility. Neurobiology of disease. vol 49. 2015-11-10. PMID:22926190. |
dominant mutations in scn1a, which encodes the nav1.1 vgsc α-subunit, underlie several forms of epilepsy, including dravet syndrome (ds) and genetic epilepsy with febrile seizures plus (gefs+). |
2015-11-10 |
2023-08-12 |
mouse |
| Matthew T Dinday, Scott C Baraba. Large-Scale Phenotype-Based Antiepileptic Drug Screening in a Zebrafish Model of Dravet Syndrome eNeuro. vol 2. issue 4. 2015-10-14. PMID:26465006. |
large-scale phenotype-based antiepileptic drug screening in a zebrafish model of dravet syndrome mutations in a voltage-gated sodium channel (scn1a) result in dravet syndrome (ds), a catastrophic childhood epilepsy. |
2015-10-14 |
2023-08-13 |
zebrafish |
| Ricardo Zavala-Yoé, Ricardo Ramírez-Mendoza, Luz M Corder. Novel way to investigate evolution of children refractory epilepsy by complexity metrics in massive information. SpringerPlus. vol 4. 2015-08-28. PMID:26312202. |
among them, some children epilepsies are peculiarly difficult to deal with as doose syndrome (ds). |
2015-08-28 |
2023-08-13 |
Not clear |