| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tal Benoliel, Tal Gilboa, Paz Har-Shai Yahav, Revital Zelker, Bilha Kreigsberg, Evgeny Tsizin, Oshrit Arviv, Dana Ekstein, Mordekhay Medvedovsk. Digital Semiology: A Prototype for Standardized, Computer-Based Semiologic Encoding of Seizures. Frontiers in neurology. vol 12. 2021-10-23. PMID:34675865. |
sixty episodes from a mixed adult and pediatric cohort from one level 4 epilepsy center vem archives were analyzed using ds and the reports were compared with the standard freeform ones, written by the same epileptologists. |
2021-10-23 |
2023-08-13 |
Not clear |
| Cara J Westmark, Crystal M Hervey, Elizabeth M Berry-Kravis, James S Malte. Effect of Anticoagulants on Amyloid β-Protein Precursor and Amyloid Beta Levels in Plasma. Journal of Alzheimer's disease & Parkinsonism. vol 1. 2021-10-21. PMID:23459194. |
altered levels of amyloid β-protein precursor (aβpp) and/or amyloid beta (aβ) are characteristic of several neurological disorders including alzheimer's disease (ad), down syndrome (ds), fragile x syndrome (fxs), parkinson's disease (pd), autism and epilepsy. |
2021-10-21 |
2023-08-12 |
Not clear |
| Chia-Hsuan Huang, Pi-Lien Hung, Pi-Chuan Fan, Kuang-Lin Lin, Ting-Rong Hsu, I-Jun Chou, Che-Sheng Ho, I-Ching Chou, Wei-Sheng Lin, Inn-Chi Lee, Hueng-Chuen Fan, Shyi-Jou Chen, Jao-Shwann Liang, Yi-Fang Tu, Tung-Ming Chang, Su-Ching Hu, Lee-Chin Wong, Kun-Long Hung, Wang-Tso Le. Clinical spectrum and the comorbidities of Dravet syndrome in Taiwan and the possible molecular mechanisms. Scientific reports. vol 11. issue 1. 2021-10-16. PMID:34642351. |
dravet syndrome (ds) is an uncommon epilepsy syndrome that may negatively affect the patients and their caregivers. |
2021-10-16 |
2023-08-13 |
Not clear |
| Chelsea D Pernici, Jeffrey A Mensah, E Jill Dahle, Kristina J Johnson, Laura Handy, Lauren Buxton, Misty D Smith, Peter J West, Cameron S Metcalf, Karen S Wilco. Development of an antiseizure drug screening platform for Dravet syndrome at the NINDS contract site for the Epilepsy Therapy Screening Program. Epilepsia. vol 62. issue 7. 2021-10-15. PMID:34002394. |
to facilitate the development of asds for ds, the contract site of the national institute of neurological disorders and stroke (ninds) epilepsy therapy screening program (etsp) has evaluated a mouse model of ds using the conditional knock-in scn1a |
2021-10-15 |
2023-08-13 |
mouse |
| Antara Das, Martin A Smith, Diane K O'Dow. A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy. Journal of visualized experiments : JoVE. issue 173. 2021-10-15. PMID:34309607. |
scn1a mutations can result in a large variety of seizure phenotype ranging from simple, self-limited fever-associated febrile seizures (fs), moderate-level genetic epilepsy with febrile seizures plus (gefs+) to more severe dravet syndrome (ds). |
2021-10-15 |
2023-08-13 |
mouse |
| Masahiro Kanatani, Tadashi Adachi, Ryoichi Sakata, Yoko Nishimura, Yoshiaki Saito, Yoshihiro Maegaki, Yasuhiro Watanabe, Ritsuko Hanajim. Dravet syndrome with parkinsonian symptoms and intact dopaminergic neurons: A case report. Brain & development. vol 43. issue 3. 2021-10-04. PMID:33199159. |
dravet syndrome (ds) is severe myoclonic epilepsy in infancy and associated with a heterozygous mutation of the gene for the sodium channel alpha 1 subunit (scn1a). |
2021-10-04 |
2023-08-13 |
Not clear |
| Domenica Battaglia, Daniela Chieffo, Simona Lucibello, Carla Marini, Valentina Sibilia, Davide Mei, Francesca Darra, Francesca Offredi, Elena Fontana, Nicola Specchio, Simona Cappelletti, Tiziana Granata, Francesca Ragona, Mara Patrini, Maria G Baglietto, Giulia Prato, Annarita Ferrari, Federico Vigevano, Eugenio Mercuri, Bernardo Dalla Bernardina, Renzo Guerrini, Charlotte Dravet, Francesco Guzzett. Multicenter prospective longitudinal study in 34 patients with Dravet syndrome: Neuropsychological development in the first six years of life. Brain & development. vol 43. issue 3. 2021-10-04. PMID:33478845. |
the objective of this study was to identify developmental trajectories of developmental/behavioral phenotypes and possibly their relationship to epilepsy and genotype by analyzing developmental and behavioral features collected prospectively and longitudinally in a cohort of patients with dravet syndrome (ds). |
2021-10-04 |
2023-08-13 |
human |
| Adam Strzelczyk, Milka Pringsheim, Thomas Mayer, Tilman Polster, Kerstin A Klotz, Hiltrud Muhle, Michael Alber, Regina Trollmann, Hartwig Spors, Gerhard Kluger, Gerhard Kurlemann, Susanne Schubert-Bas. Efficacy, tolerability, and retention of fenfluramine for the treatment of seizures in patients with Dravet syndrome: Compassionate use program in Germany. Epilepsia. vol 62. issue 10. 2021-10-01. PMID:34378197. |
dravet syndrome (ds) is a rare but severe drug-resistant epilepsy. |
2021-10-01 |
2023-08-13 |
Not clear |
| Margherita Bertuccelli, Karen Verheyen, Ann Hallemans, Josemir W Sander, Francesca Ragona, Patrizia Bisiacchi, Stefano Masiero, Alessandra Del Felic. Deconstructing Dravet syndrome neurocognitive development: A scoping review. Epilepsia. vol 62. issue 4. 2021-09-21. PMID:33646591. |
dravet syndrome (ds) is a rare severe epilepsy syndrome associated with slowed psychomotor development and behavioral disorders from the second year onward in a previously seemingly normal child. |
2021-09-21 |
2023-08-13 |
Not clear |
| Shu-Hui Chuang, Ruth E Westenbroek, Nephi Stella, William A Catteral. Combined Antiseizure Efficacy of Cannabidiol and Clonazepam in a Conditional Mouse Model of Dravet Syndrome. Journal of experimental neurology. vol 2. issue 2. 2021-07-27. PMID:34308420. |
dravet syndrome (ds) is a severe childhood epilepsy caused by heterozygous loss-of-function mutations in the |
2021-07-27 |
2023-08-13 |
mouse |
| Andreas Brunklaus, Stephanie Schorge, Alexander D Smith, Ismael Ghanty, Kirsty Stewart, Sarah Gardiner, Juanjiangmeng Du, Eduardo Pérez-Palma, Joseph D Symonds, Abby C Collier, Dennis Lal, Sameer M Zuber. SCN1A variants from bench to bedside-improved clinical prediction from functional characterization. Human mutation. vol 41. issue 2. 2021-07-22. PMID:31782251. |
variants in the scn1a gene are associated with a wide range of disorders including genetic epilepsy with febrile seizures plus (gefs+), familial hemiplegic migraine (fhm), and the severe childhood epilepsy dravet syndrome (ds). |
2021-07-22 |
2023-08-13 |
Not clear |
| Lore Wyers, Karen Verheyen, Berten Ceulemans, An-Sofie Schoonjans, Kaat Desloovere, Patricia Van de Walle, Ann Halleman. The mechanics behind gait problems in patients with Dravet Syndrome. Gait & posture. vol 84. 2021-07-16. PMID:33445141. |
dravet syndrome (ds) is a developmental and epileptic encephalopathy starting in infancy and characterised by treatment resistant epilepsy with cognitive impairment and progressive motor dysfunction. |
2021-07-16 |
2023-08-13 |
Not clear |
| Wesley T Kerr, Xingruo Zhang, Chloe E Hill, Emily A Janio, Andrea M Chau, Chelsea T Braesch, Justine M Le, Jessica M Hori, Akash B Patel, Corinne H Allas, Amir H Karimi, Ishita Dubey, Siddhika S Sreenivasan, Norma L Gallardo, Janar Bauirjan, Eric S Hwang, Emily C Davis, Shannon R D'Ambrosio, Mona Al Banna, Andrew Y Cho, Sandra R Dewar, Jerome Engel, Jamie D Feusner, John M Ster. Epilepsy, dissociative seizures, and mixed: Associations with time to video-EEG. Seizure. vol 86. 2021-07-12. PMID:33601302. |
video-electroencephalographic monitoring (vem) is a core component to the diagnosis and evaluation of epilepsy and dissociative seizures (ds)-also known as functional or psychogenic seizures-but vem evaluation often occurs later than recommended. |
2021-07-12 |
2023-08-13 |
Not clear |
| Miren Altuna, Sandra Giménez, Juan Forte. Epilepsy in Down Syndrome: A Highly Prevalent Comorbidity. Journal of clinical medicine. vol 10. issue 13. 2021-07-11. PMID:34202784. |
individuals with down syndrome (ds) have an increased risk for epilepsy during the whole lifespan, but especially after age 40 years. |
2021-07-11 |
2023-08-13 |
Not clear |
| Miren Altuna, Sandra Giménez, Juan Forte. Epilepsy in Down Syndrome: A Highly Prevalent Comorbidity. Journal of clinical medicine. vol 10. issue 13. 2021-07-11. PMID:34202784. |
the increase in the number of individuals with ds living into late middle age due to improved health care is resulting in an increase in epilepsy prevalence in this population. |
2021-07-11 |
2023-08-13 |
Not clear |
| Miren Altuna, Sandra Giménez, Juan Forte. Epilepsy in Down Syndrome: A Highly Prevalent Comorbidity. Journal of clinical medicine. vol 10. issue 13. 2021-07-11. PMID:34202784. |
this late onset epilepsy is linked to the development of symptomatic alzheimer's disease (ad), which is the main comorbidity in adults with ds with a cumulative incidence of more than 90% of adults by the seventh decade. |
2021-07-11 |
2023-08-13 |
Not clear |
| Miren Altuna, Sandra Giménez, Juan Forte. Epilepsy in Down Syndrome: A Highly Prevalent Comorbidity. Journal of clinical medicine. vol 10. issue 13. 2021-07-11. PMID:34202784. |
more than 50% of patients with ds and ad dementia will most likely develop epilepsy, which in this context has a specific clinical presentation in the form of generalized myoclonic epilepsy. |
2021-07-11 |
2023-08-13 |
Not clear |
| Miren Altuna, Sandra Giménez, Juan Forte. Epilepsy in Down Syndrome: A Highly Prevalent Comorbidity. Journal of clinical medicine. vol 10. issue 13. 2021-07-11. PMID:34202784. |
raised awareness and a better understanding of epilepsy in ds from families, caregivers and clinicians could enable earlier diagnoses and better treatments for individuals with ds. |
2021-07-11 |
2023-08-13 |
Not clear |
| Simona Lattanzi, Francesco Brigo, Eugen Trinka, Gaetano Zaccara, Pasquale Striano, Cinzia Del Giovane, Mauro Silvestrin. Adjunctive Cannabidiol in Patients with Dravet Syndrome: A Systematic Review and Meta-Analysis of Efficacy and Safety. CNS drugs. vol 34. issue 3. 2021-06-11. PMID:32040850. |
dravet syndrome (ds) is one of the most severe forms of drug-resistant epilepsy and available interventions fail to control seizures in most patients. |
2021-06-11 |
2023-08-13 |
Not clear |
| Piero Pavone, Xena Giada Pappalardo, Simona D Marino, Laura Sciuto, Giovanni Corsello, Martino Ruggieri, Enrico Parano, Maria Piccione, Raffaele Falsaperl. A novel GABRB3 variant in Dravet syndrome: Case report and literature review. Molecular genetics & genomic medicine. vol 8. issue 11. 2021-06-07. PMID:32945607. |
mutations in gabrb3 have been identified in subjects with different types of epilepsy and epileptic syndromes, including west syndrome (ws), dravet syndrome (ds), lennox-gastaut syndrome (lgs), myoclonic-atonic epilepsy (mae), and others. |
2021-06-07 |
2023-08-13 |
human |