| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nianhui Zhang, Weizheng Wei, Istvan Mody, Carolyn R House. Altered localization of GABA(A) receptor subunits on dentate granule cell dendrites influences tonic and phasic inhibition in a mouse model of epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 28. 2007-08-07. PMID:17626213. |
complex changes in gaba(a) receptors (gaba(a)rs) in animal models of temporal lobe epilepsy during the chronic period include a decrease in the delta subunit and increases in the alpha4 and gamma2 subunits in the dentate gyrus. |
2007-08-07 |
2023-08-12 |
mouse |
| Alexander Fahrner, Gunda Kann, Armin Flubacher, Christophe Heinrich, Thomas M Freiman, Josef Zentner, Michael Frotscher, Carola A Haa. Granule cell dispersion is not accompanied by enhanced neurogenesis in temporal lobe epilepsy patients. Experimental neurology. vol 203. issue 2. 2007-03-20. PMID:17049346. |
granule cell dispersion (gcd) in the dentate gyrus is a frequent feature of ammon's horn sclerosis (ahs) which is often associated with temporal lobe epilepsy (tle). |
2007-03-20 |
2023-08-12 |
human |
| B Tu, Y Jiao, H Herzog, J V Nadle. Neuropeptide Y regulates recurrent mossy fiber synaptic transmission less effectively in mice than in rats: Correlation with Y2 receptor plasticity. Neuroscience. vol 143. issue 4. 2007-02-23. PMID:17027162. |
a unique feature of temporal lobe epilepsy is the formation of recurrent excitatory connections among granule cells of the dentate gyrus as a result of mossy fiber sprouting. |
2007-02-23 |
2023-08-12 |
mouse |
| YogendraSinh H Raol, Ingrid V Lund, Sabita Bandyopadhyay, Guojun Zhang, Daniel S Roberts, John H Wolfe, Shelley J Russek, Amy R Brooks-Kaya. Enhancing GABA(A) receptor alpha 1 subunit levels in hippocampal dentate gyrus inhibits epilepsy development in an animal model of temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 44. 2006-11-14. PMID:17079662. |
enhancing gaba(a) receptor alpha 1 subunit levels in hippocampal dentate gyrus inhibits epilepsy development in an animal model of temporal lobe epilepsy. |
2006-11-14 |
2023-08-12 |
rat |
| Tae-Cheon Kang, Duk-Soo Kim, Sung-Eun Kwak, Ji-Eun Kim, Moo Ho Won, Dae-Won Kim, Soo-Young Choi, Oh-Shin Kwo. Epileptogenic roles of astroglial death and regeneration in the dentate gyrus of experimental temporal lobe epilepsy. Glia. vol 54. issue 4. 2006-10-02. PMID:16845674. |
epileptogenic roles of astroglial death and regeneration in the dentate gyrus of experimental temporal lobe epilepsy. |
2006-10-02 |
2023-08-12 |
Not clear |
| Guo-Liang Li, Ning Zhang, Jing Li, Dan-Tong Zhu, Zhi-Guo Wu, Bo Xia. [Mossy fiber sprouting and synapse formation in the dentate gyrus of temporal lobe epilepsy rats induced by pilocarpine]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 29. issue 4. 2006-09-19. PMID:16134595. |
[mossy fiber sprouting and synapse formation in the dentate gyrus of temporal lobe epilepsy rats induced by pilocarpine]. |
2006-09-19 |
2023-08-12 |
rat |
| Guo-Liang Li, Ning Zhang, Jing Li, Dan-Tong Zhu, Zhi-Guo Wu, Bo Xia. [Mossy fiber sprouting and synapse formation in the dentate gyrus of temporal lobe epilepsy rats induced by pilocarpine]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 29. issue 4. 2006-09-19. PMID:16134595. |
to investigate the relationship between mossy fiber axon sprouting (mfs), synaptic reorganization in the dentate gyrus, and the mechanism of chronic temporal lobe epilepsy induced by pilocarpine. |
2006-09-19 |
2023-08-12 |
rat |
| Debora Ledergerber, Jean-Marc Fritschy, Jason E Krali. Impairment of dentate gyrus neuronal progenitor cell differentiation in a mouse model of temporal lobe epilepsy. Experimental neurology. vol 199. issue 1. 2006-08-10. PMID:16624297. |
impairment of dentate gyrus neuronal progenitor cell differentiation in a mouse model of temporal lobe epilepsy. |
2006-08-10 |
2023-08-12 |
mouse |
| Sanjay S Kumar, Paul S Buckmaste. Hyperexcitability, interneurons, and loss of GABAergic synapses in entorhinal cortex in a model of temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 17. 2006-05-23. PMID:16641241. |
layer ii stellate cells of the entorhinal cortex, which are hyperexcitable in animal models of temporal lobe epilepsy, provide the predominant synaptic input to the hippocampal dentate gyrus. |
2006-05-23 |
2023-08-12 |
rat |
| Ashok K Shetty, Vandana Zaman, Bharathi Hattiangad. Repair of the injured adult hippocampus through graft-mediated modulation of the plasticity of the dentate gyrus in a rat model of temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 37. 2006-03-06. PMID:16162921. |
repair of the injured adult hippocampus through graft-mediated modulation of the plasticity of the dentate gyrus in a rat model of temporal lobe epilepsy. |
2006-03-06 |
2023-08-12 |
rat |
| Zechun Peng, Carolyn R House. Temporal patterns of fos expression in the dentate gyrus after spontaneous seizures in a mouse model of temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 31. 2006-02-07. PMID:16079403. |
temporal patterns of fos expression in the dentate gyrus after spontaneous seizures in a mouse model of temporal lobe epilepsy. |
2006-02-07 |
2023-08-12 |
mouse |
| Zechun Peng, Carolyn R House. Temporal patterns of fos expression in the dentate gyrus after spontaneous seizures in a mouse model of temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 31. 2006-02-07. PMID:16079403. |
the findings in this mouse model are consistent with previous suggestions that spontaneous seizures in temporal lobe epilepsy may result from a periodic breakdown of the normal filter functions of the dentate gyrus and a resulting increase in hypersynchronous activity of dentate granule cells. |
2006-02-07 |
2023-08-12 |
mouse |
| Jason E Kralic, Debora A Ledergerber, Jean-Marc Fritsch. Disruption of the neurogenic potential of the dentate gyrus in a mouse model of temporal lobe epilepsy with focal seizures. The European journal of neuroscience. vol 22. issue 8. 2005-12-15. PMID:16262631. |
disruption of the neurogenic potential of the dentate gyrus in a mouse model of temporal lobe epilepsy with focal seizures. |
2005-12-15 |
2023-08-12 |
mouse |
| Terhi J Pirttilä, Anni Manninen, Leena Jutila, Jari Nissinen, Reetta Kälviäinen, Matti Vapalahti, Arto Immonen, Leo Paljärvi, Kari Karkola, Irina Alafuzoff, Esa Mervaala, Asla Pitkäne. Cystatin C expression is associated with granule cell dispersion in epilepsy. Annals of neurology. vol 58. issue 2. 2005-10-31. PMID:16049933. |
human temporal lobe epilepsy (tle) is associated with cellular alterations (eg, hilar cell death, neurogenesis, and granule cell dispersion) in the dentate gyrus but their underlying molecular mechanism are not known. |
2005-10-31 |
2023-08-12 |
human |
| Claire Leroy, Pierrick Poisbeau, A Florence Keller, Astrid Nehli. Pharmacological plasticity of GABA(A) receptors at dentate gyrus synapses in a rat model of temporal lobe epilepsy. The Journal of physiology. vol 557. issue Pt 2. 2005-01-05. PMID:15034126. |
pharmacological plasticity of gaba(a) receptors at dentate gyrus synapses in a rat model of temporal lobe epilepsy. |
2005-01-05 |
2023-08-12 |
rat |
| Ryuta Koyama, Maki K Yamada, Shigeyoshi Fujisawa, Ritsuko Katoh-Semba, Norio Matsuki, Yuji Ikegay. Brain-derived neurotrophic factor induces hyperexcitable reentrant circuits in the dentate gyrus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 33. 2004-11-08. PMID:15317847. |
aberrant sprouting and synaptic reorganization of the mossy fiber (mf) axons are commonly found in the hippocampus of temporal lobe epilepsy patients and result in the formation of excitatory feedback loops in the dentate gyrus, a putative cellular basis for recurrent epileptic seizures. |
2004-11-08 |
2023-08-12 |
Not clear |
| Robert S Sloviter, Hemant S Kudrimoti, Kenneth D Laxer, Nicholas M Barbaro, Stephen Chan, Lawrence J Hirsch, Robert R Goodman, Timothy A Pedle. "Tectonic" hippocampal malformations in patients with temporal lobe epilepsy. Epilepsy research. vol 59. issue 2-3. 2004-10-12. PMID:15246116. |
histological analysis of hippocampi removed en bloc during surgical treatment of temporal lobe epilepsy revealed a subgroup of patients with bulbous expansions of the ca1 pyramidal cell/subicular layers that were consistently accompanied by "tectonic" invaginations of the adjacent dentate gyrus. |
2004-10-12 |
2023-08-12 |
Not clear |
| Jenifer E Austin, Paul S Buckmaste. Recurrent excitation of granule cells with basal dendrites and low interneuron density and inhibitory postsynaptic current frequency in the dentate gyrus of macaque monkeys. The Journal of comparative neurology. vol 476. issue 3. 2004-10-07. PMID:15269966. |
temporal lobe epilepsy is often associated with pathological changes in the dentate gyrus, and such changes may be more common in humans than in some nonprimate species. |
2004-10-07 |
2023-08-12 |
human |
| Ronald S Winokur, Timothy Kubal, Dan Liu, Scott F Davis, Bret N Smit. Recurrent excitation in the dentate gyrus of a murine model of temporal lobe epilepsy. Epilepsy research. vol 58. issue 2-3. 2004-07-06. PMID:15120741. |
recurrent excitation in the dentate gyrus of a murine model of temporal lobe epilepsy. |
2004-07-06 |
2023-08-12 |
mouse |
| Anna d H Ratzliff, Allyson L Howard, Vijayalakshmi Santhakumar, Imola Osapay, Ivan Soltes. Rapid deletion of mossy cells does not result in a hyperexcitable dentate gyrus: implications for epileptogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 9. 2004-05-14. PMID:14999076. |
loss of cells from the hilus of the dentate gyrus is a major histological hallmark of human temporal lobe epilepsy. |
2004-05-14 |
2023-08-12 |
human |