| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lucia Wittner, Gilles Huberfeld, Stéphane Clémenceau, Loránd Eross, Edouard Dezamis, László Entz, István Ulbert, Michel Baulac, Tamás F Freund, Zsófia Maglóczky, Richard Mile. The epileptic human hippocampal cornu ammonis 2 region generates spontaneous interictal-like activity in vitro. Brain : a journal of neurology. vol 132. issue Pt 11. 2010-01-15. PMID:19767413. |
the dentate gyrus, the cornu ammonis 2 region and the subiculum of the human hippocampal formation are resistant to the cell loss associated with temporal lobe epilepsy. |
2010-01-15 |
2023-08-12 |
human |
| Christina C Young, Michael Stegen, René Bernard, Martin Müller, Josef Bischofberger, Rüdiger W Veh, Carola A Haas, Jakob Wolfar. Upregulation of inward rectifier K+ (Kir2) channels in dentate gyrus granule cells in temporal lobe epilepsy. The Journal of physiology. vol 587. issue Pt 17. 2009-12-14. PMID:19564397. |
in humans, temporal lobe epilepsy (tle) is often associated with ammon's horn sclerosis (ahs) characterized by hippocampal cell death, gliosis and granule cell dispersion (gcd) in the dentate gyrus. |
2009-12-14 |
2023-08-12 |
mouse |
| Yaima del Carmen Garrido Sanabria, Gustavo Adolfo Argañaraz, Eliangela Lima, Margareth Rose Priel, Edvaldo da Silva Trindade, Luana Mazzacoratti Loeb, Fulvio Alexandre Scorza, Esper Abrão Cavalheiro, Débora Amado, Maria da Graça Naffah-Mazzacoratt. Neurogenesis induced by seizures in the dentate gyrus is not related to mossy fiber sprouting but is age dependent in developing rats. Arquivos de neuro-psiquiatria. vol 66. issue 4. 2009-11-12. PMID:19099125. |
neurogenesis in the dentate gyrus (dg) has attracted attention since abnormal supragranular mossy fiber sprouting occurs in the same region, in temporal lobe epilepsy. |
2009-11-12 |
2023-08-12 |
rat |
| Ren-Zhi Zhan, J Victor Nadle. Enhanced tonic GABA current in normotopic and hilar ectopic dentate granule cells after pilocarpine-induced status epilepticus. Journal of neurophysiology. vol 102. issue 2. 2009-09-24. PMID:19474175. |
in temporal lobe epilepsy, loss of inhibitory neurons and circuit changes in the dentate gyrus promote hyperexcitability. |
2009-09-24 |
2023-08-12 |
rat |
| Si Zhang, Sanjay Khanna, Feng Ru Tan. Patterns of hippocampal neuronal loss and axon reorganization of the dentate gyrus in the mouse pilocarpine model of temporal lobe epilepsy. Journal of neuroscience research. vol 87. issue 5. 2009-06-01. PMID:19025771. |
patterns of hippocampal neuronal loss and axon reorganization of the dentate gyrus in the mouse pilocarpine model of temporal lobe epilepsy. |
2009-06-01 |
2023-08-12 |
mouse |
| Si Zhang, Sanjay Khanna, Feng Ru Tan. Patterns of hippocampal neuronal loss and axon reorganization of the dentate gyrus in the mouse pilocarpine model of temporal lobe epilepsy. Journal of neuroscience research. vol 87. issue 5. 2009-06-01. PMID:19025771. |
the patterns of hippocampal neuronal loss and rewiring of the dentate gyrus (dg) were studied in the mouse model of temporal lobe epilepsy at 2 months after pilocarpine-induced status epilepticus (pise). |
2009-06-01 |
2023-08-12 |
mouse |
| Hajnalka Abrahám, Béla Veszprémi, András Kravják, Krisztina Kovács, Eva Gömöri, László Seres. Ontogeny of calbindin immunoreactivity in the human hippocampal formation with a special emphasis on granule cells of the dentate gyrus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 27. issue 2. 2009-05-18. PMID:19150647. |
our results indicate that (i) cb is expressed by hippocampal pyramidal cells a few weeks before midgestation; (ii) similarly to rodents, migration of postmitotic human hippocampal pyramidal cells follows the inside-out gradient; (iii) cb was expressed transiently in pyramidal cells of the ca3 area of the human hippocampus; (iv) granule cells of the dentate gyrus start to express cb as early as midgestation; (v) maturation and migration of human granule cells follow the outside-in migrational gradient described in rodents and non-human primates; (vi) cb-immunoreactivity in the axon terminals of granule cells could be observed a few weeks before birth with a long-lasting increase in staining intensity postnatally; (vii) the maturation pattern of the cb-positive mossy fiber system suggests that the development of connectivity and the mature topographical termination pattern between dentate gyrus and the ca3 area of ammon's horn in humans resembles that previously described for rodents; (viii) the dorsal-ventral delay in development may explain the topography of neuropathologic alterations of the granule cell layer found in temporal lobe epilepsy related to febrile seizures. |
2009-05-18 |
2023-08-12 |
mouse |
| Wei-ping Liu, Bo Xiao, Shu-yu Li, Xiao-qin L. [Eph in the mechanism of mossy fiber axon sprouting in dentate gyrus in rats with chronic temporal lobe epilepsy]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 33. issue 8. 2009-04-28. PMID:18772502. |
[eph in the mechanism of mossy fiber axon sprouting in dentate gyrus in rats with chronic temporal lobe epilepsy]. |
2009-04-28 |
2023-08-12 |
rat |
| Wei-ping Liu, Bo Xiao, Shu-yu Li, Xiao-qin L. [Eph in the mechanism of mossy fiber axon sprouting in dentate gyrus in rats with chronic temporal lobe epilepsy]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 33. issue 8. 2009-04-28. PMID:18772502. |
to investigate the relationship among mossy fiber axon sprouting(mfs), synaptic reorganization, and the alteration of expression of eph a5 and ephrin a3 in the dentate gyrus in rats with pilocarpine-induced chronic temporal lobe epilepsy. |
2009-04-28 |
2023-08-12 |
rat |
| Martin C Müller, Matthias Osswald, Stefanie Tinnes, Ute Häussler, Anne Jacobi, Eckart Förster, Michael Frotscher, Carola A Haa. Exogenous reelin prevents granule cell dispersion in experimental epilepsy. Experimental neurology. vol 216. issue 2. 2009-04-15. PMID:19185570. |
temporal lobe epilepsy (tle) is often accompanied by granule cell dispersion (gcd), a migration defect of granule cells in the dentate gyrus. |
2009-04-15 |
2023-08-12 |
mouse |
| Robert F Hunt, Stephen W Scheff, Bret N Smit. Posttraumatic epilepsy after controlled cortical impact injury in mice. Experimental neurology. vol 215. issue 2. 2009-04-08. PMID:19013458. |
these data suggest the development of spontaneous posttraumatic seizures as well as structural and functional network changes associated with temporal lobe epilepsy in the mouse dentate gyrus by 71 d after cci injury. |
2009-04-08 |
2023-08-12 |
mouse |
| Sung-Eun Kwak, Ji-Eun Kim, Hui-Chul Choi, Hong-Ki Song, Yeong-In Kim, Seung-Mook Jo, Tae-Cheon Kan. The expression of somatostatin receptors in the hippocampus of pilocarpine-induced rat epilepsy model. Neuropeptides. vol 42. issue 5-6. 2009-02-19. PMID:18951627. |
our findings suggest that increases in neuron-glial sstr expressions may be closely related to the enhanced inhibition of the dentate gyrus and regulation of reactive microgliosis in the hippocampus of a pilocarpine model of temporal lobe epilepsy. |
2009-02-19 |
2023-08-12 |
rat |
| Robert S Slovite. Hippocampal epileptogenesis in animal models of mesial temporal lobe epilepsy with hippocampal sclerosis: the importance of the "latent period" and other concepts. Epilepsia. vol 49 Suppl 9. 2009-01-22. PMID:19087122. |
prolonged chemoconvulsant-induced status epilepticus in rats has long been promoted as an animal model of mesial temporal lobe epilepsy with hippocampal sclerosis, under the assumption that these animals involve: (1) pathology similar to that of the human neurologic condition; (2) a seizure-free, "preepileptic" latent period of several weeks duration after injury, during which a secondary epileptogenic process gradually develops; and (3) a chronic epileptic state in which the hippocampus, in general, and the dentate gyrus, in particular, becomes a source of the spontaneous behavioral seizures that define these animals as "epileptic." |
2009-01-22 |
2023-08-12 |
human |
| C M Queiroz, L E Mell. Protein tyrosine kinase inhibitors modify kainic acid-induced epileptiform activity and mossy fiber sprouting but do not protect against limbic cell death. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 41. issue 5. 2008-10-06. PMID:18545813. |
in this model of temporal lobe epilepsy, both protein kinase inhibitors diminished the acute epileptic activity triggered by ka and the ensuing morphological alterations in the dentate gyrus without diminishing cell loss. |
2008-10-06 |
2023-08-12 |
rat |
| J Pallud, B Devaux, A Depauli. [Changes in spontaneous epileptic activity after selective intrahippocampal transection in a model of chronic mesial temporal lobe epilepsy]. Neuro-Chirurgie. vol 54. issue 3. 2008-08-08. PMID:18417168. |
in this model of mesial temporal lobe epilepsy, longitudinally projecting axonal circuits of the dentate gyrus and hilus appear to be implicated in generation, propagation and interruption of ictal activities within hippocampal formation. |
2008-08-08 |
2023-08-12 |
mouse |
| Brenda E Porte. Neurogenesis and epilepsy in the developing brain. Epilepsia. vol 49 Suppl 5. 2008-08-04. PMID:18522600. |
children have more ongoing cell birth in the dentate gyrus than adults, and markers of cell division are further increased in children with refractory temporal lobe epilepsy. |
2008-08-04 |
2023-08-12 |
Not clear |
| Brenda E Porte. Neurogenesis and epilepsy in the developing brain. Epilepsia. vol 49 Suppl 5. 2008-08-04. PMID:18522600. |
future studies need to focus on how these changes in neurogenesis influence dentate gyrus function and what they imply for epileptogenesis and learning and memory impairments, so commonly found in children with temporal lobe epilepsy. |
2008-08-04 |
2023-08-12 |
Not clear |
| F Edward Dudek, Thomas P Sutul. Epileptogenesis in the dentate gyrus: a critical perspective. Progress in brain research. vol 163. 2008-03-14. PMID:17765749. |
the dentate gyrus has long been a focal point for studies on the molecular, cellular, and network mechanisms responsible for epileptogenesis in temporal lobe epilepsy (tle). |
2008-03-14 |
2023-08-12 |
Not clear |
| Philip A Williams, Phillip Larimer, Yuan Gao, Ben W Strowbridg. Semilunar granule cells: glutamatergic neurons in the rat dentate gyrus with axon collaterals in the inner molecular layer. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 50. 2008-01-22. PMID:18077687. |
semilunar granule cells appear to represent a distinct excitatory neuron population in the dentate gyrus that may be an important target for mossy fiber sprouting in patients and rodent models of temporal lobe epilepsy. |
2008-01-22 |
2023-08-12 |
rat |
| Gabriel Maisonnave Arisi, Norberto Garcia-Cairasc. Doublecortin-positive newly born granule cells of hippocampus have abnormal apical dendritic morphology in the pilocarpine model of temporal lobe epilepsy. Brain research. vol 1165. 2007-10-26. PMID:17662262. |
here, we describe dentate gyrus newly born granule cells morphology in rats' temporal lobe epilepsy pilocarpine model. |
2007-10-26 |
2023-08-12 |
rat |