| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hayley Crawford, Joanna Moss, Laura Groves, Robyn Dowlen, Lisa Nelson, Donna Reid, Chris Olive. A Behavioural Assessment of Social Anxiety and Social Motivation in Fragile X, Cornelia de Lange and Rubinstein-Taybi Syndromes. Journal of autism and developmental disorders. vol 50. issue 1. 2020-03-30. PMID:31541420. |
here, the effects of adult familiarity and nature of interaction on social anxiety and social motivation were investigated in individuals with fragile x (fxs; n = 20), cornelia de lange (cdls; n = 20) and rubinstein-taybi (rts; n = 20) syndromes, compared to individuals with down syndrome (ds; n = 20). |
2020-03-30 |
2023-08-13 |
human |
| Michael S Rafi. Tau PET Imaging for Staging of Alzheimer's Disease in Down Syndrome. Developmental neurobiology. vol 79. issue 7. 2020-03-27. PMID:30536948. |
alzheimer's disease (ad) pathology and early-onset dementia develop almost universally in down syndrome (ds). |
2020-03-27 |
2023-08-13 |
Not clear |
| E Zamponi, P R Helguer. The Shape of Mitochondrial Dysfunction in Down Syndrome. Developmental neurobiology. vol 79. issue 7. 2020-03-27. PMID:30830726. |
oxidative stress (os) and mitochondrial dysfunction (md) have been extensively studied and defined as therapeutic targets in down syndrome (ds). |
2020-03-27 |
2023-08-13 |
Not clear |
| Christy M Kelley, Stephen D Ginsberg, Melissa J Alldred, Barbara J Strupp, Elliott J Mufso. Maternal Choline Supplementation Alters Basal Forebrain Cholinergic Neuron Gene Expression in the Ts65Dn Mouse Model of Down Syndrome. Developmental neurobiology. vol 79. issue 7. 2020-03-27. PMID:31120189. |
down syndrome (ds), trisomy 21, is marked by intellectual disability and a premature aging profile including degeneration of the basal forebrain cholinergic neuron (bfcn) projection system, similar to alzheimer's disease (ad). |
2020-03-27 |
2023-08-13 |
mouse |
| María Carmona-Iragui, Laura Videla, Alberto Lleó, Juan Forte. Down syndrome, Alzheimer disease, and cerebral amyloid angiopathy: The complex triangle of brain amyloidosis. Developmental neurobiology. vol 79. issue 7. 2020-03-27. PMID:31278851. |
down syndrome (ds) is the main genetic cause of intellectual disability worldwide. |
2020-03-27 |
2023-08-13 |
Not clear |
| Pasquale D'Acunzo, Tal Hargash, Monika Pawlik, Chris N Goulbourne, Rocío Pérez-González, Efrat Lev. Enhanced generation of intraluminal vesicles in neuronal late endosomes in the brain of a Down syndrome mouse model with endosomal dysfunction. Developmental neurobiology. vol 79. issue 7. 2020-03-27. PMID:31278881. |
down syndrome (ds) is a human genetic disease caused by trisomy of chromosome 21 and characterized by early developmental brain abnormalities. |
2020-03-27 |
2023-08-13 |
mouse |
| Eric D Hamlett, Angela LaRosa, Elliott J Mufson, Juan Fortea, Aurélie Ledreux, Ann-Charlotte Granhol. Exosome release and cargo in Down syndrome. Developmental neurobiology. vol 79. issue 7. 2020-03-27. PMID:31347291. |
down syndrome (ds) is a multisystem disorder affecting 1 in 800 births worldwide. |
2020-03-27 |
2023-08-13 |
Not clear |
| Eric E Abrahamson, Elizabeth Head, Ira T Lott, Benjamin L Handen, Elliott J Mufson, Bradley T Christian, William E Klunk, Milos D Ikonomovi. Neuropathological correlates of amyloid PET imaging in Down syndrome. Developmental neurobiology. vol 79. issue 7. 2020-03-27. PMID:31379087. |
down syndrome (ds) results in an overproduction of amyloid-β (aβ) peptide associated with early onset of alzheimer's disease (ad). |
2020-03-27 |
2023-08-13 |
human |
| Falah Alhajraf, Deborah Ness, Abdul Hye, Andre Strydo. Plasma amyloid and tau as dementia biomarkers in Down syndrome: Systematic review and meta-analyses. Developmental neurobiology. vol 79. issue 7. 2020-03-27. PMID:31389176. |
individuals with down syndrome (ds) are at high risk of developing alzheimer's disease (ad). |
2020-03-27 |
2023-08-13 |
Not clear |
| Melissa E Petersen, Sid E O'Bryan. Blood-based biomarkers for Down syndrome and Alzheimer's disease: A systematic review. Developmental neurobiology. vol 79. issue 7. 2020-03-27. PMID:31389185. |
down syndrome (ds) occurs due to triplication of chromosome 21. |
2020-03-27 |
2023-08-13 |
Not clear |
| Thomas J Gross, Eric Doran, Amrita K Cheema, Elizabeth Head, Ira T Lott, Mark Mapston. Plasma metabolites related to cellular energy metabolism are altered in adults with Down syndrome and Alzheimer's disease. Developmental neurobiology. vol 79. issue 7. 2020-03-27. PMID:31419370. |
down syndrome (ds) is a well-known neurodevelopmental disorder most commonly caused by trisomy of chromosome 21. |
2020-03-27 |
2023-08-13 |
Not clear |
| Anne E Roll, Barbara J Bower. Building and Connecting: Family Strategies for Developing Social Support Networks for Adults With Down Syndrome. Journal of family nursing. vol 25. issue 1. 2020-03-26. PMID:30675807. |
while this is particularly the case for people with down syndrome (ds), our knowledge of how their support networks are developed is limited. |
2020-03-26 |
2023-08-13 |
Not clear |
| Fiorenza Stagni, Maria Elisa Salvalai, Andrea Giacomini, Marco Emili, Beatrice Uguagliati, Er Xia, Mariagrazia Grilli, Renata Bartesaghi, Sandra Guid. Neonatal treatment with cyclosporine A restores neurogenesis and spinogenesis in the Ts65Dn model of Down syndrome. Neurobiology of disease. vol 129. 2020-03-24. PMID:31085229. |
down syndrome (ds), a genetic condition due to triplication of chromosome 21, is characterized by reduced proliferation of neural progenitor cells (npcs) starting from early life stages. |
2020-03-24 |
2023-08-13 |
mouse |
| Angela F Lukowski, Helen M Milojevich, Lauren Eale. Cognitive Functioning in Children with Down Syndrome: Current Knowledge and Future Directions. Advances in child development and behavior. vol 56. 2020-03-23. PMID:30846049. |
infants and children with down syndrome (ds) can look forward toward bright futures, as individuals with ds are living healthier, more productive lives than ever due to medical advances, opportunities for early and continued intervention, and inclusive education. |
2020-03-23 |
2023-08-13 |
Not clear |
| Tiffany J Glass, Sara L Twadell, Luke C Valmadrid, Nadine P Conno. Early impacts of modified food consistency on oromotor outcomes in mouse models of Down syndrome. Physiology & behavior. vol 199. 2020-03-19. PMID:30496741. |
down syndrome (ds) in humans is associated with differences of the central nervous system and oromotor development. |
2020-03-19 |
2023-08-13 |
mouse |
| Tiffany J Glass, Sara L Twadell, Luke C Valmadrid, Nadine P Conno. Early impacts of modified food consistency on oromotor outcomes in mouse models of Down syndrome. Physiology & behavior. vol 199. 2020-03-19. PMID:30496741. |
therefore, experimental food consistency paradigms are of interest to oromotor investigations in mouse models of down syndrome (ds). |
2020-03-19 |
2023-08-13 |
mouse |
| Matthew B Johnson, Elisa De Franco, Siri Atma W Greeley, Lisa R Letourneau, Kathleen M Gillespie, Matthew N Wakeling, Sian Ellard, Sarah E Flanagan, Kashyap A Patel, Andrew T Hattersle. Trisomy 21 Is a Cause of Permanent Neonatal Diabetes That Is Autoimmune but Not HLA Associated. Diabetes. vol 68. issue 7. 2020-03-16. PMID:30962220. |
patients with down syndrome (ds) resulting from trisomy 21 are four times more likely to have childhood diabetes with an intermediate hla association. |
2020-03-16 |
2023-08-13 |
Not clear |
| Sergio Valbuena, Álvaro García, Wilfrid Mazier, Ana V Paternain, Juan Lerm. Unbalanced dendritic inhibition of CA1 neurons drives spatial-memory deficits in the Ts2Cje Down syndrome model. Nature communications. vol 10. issue 1. 2020-03-16. PMID:31676751. |
memory impairment) in mouse models of down syndrome (ds). |
2020-03-16 |
2023-08-13 |
mouse |
| Stefanos Aivazidis, Abhilasha Jain, Abhishek K Rauniyar, Colin C Anderson, John O Marentette, David J Orlicky, Kristofer S Fritz, Peter S Harris, David Siegel, Kenneth N Maclean, James R Roed. SNARE proteins rescue impaired autophagic flux in Down syndrome. PloS one. vol 14. issue 11. 2020-03-16. PMID:31714914. |
down syndrome (ds) is a chromosomal disorder caused by trisomy of chromosome 21 (ts21). |
2020-03-16 |
2023-08-13 |
human |
| Camila Faria Carrada, Flávia Almeida Ribeiro Scalioni, Lucas Guimarães Abreu, Rosangela Almeida Ribeiro, Saul Martins Paiv. Impact of oral conditions of children/adolescents with Down syndrome on their families' quality of life. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry. vol 40. issue 2. 2020-03-13. PMID:31885104. |
to assess the impact of oral conditions among children/adolescents with down syndrome (ds) on the oral health-related quality of life (ohrqol) of their families in comparison with a group without ds. |
2020-03-13 |
2023-08-13 |
Not clear |