| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David A Geier, Janet K Kern, Mark R Geie. Down syndrome as a genetic model to evaluate the role of oxidative stress and transsulfuration abnormalities in autism spectrum disorder: A 10-year longitudinal cohort study. Developmental neurobiology. vol 79. issue 9-10. 2020-06-11. PMID:31742925. |
down syndrome (ds) is a genetic disorder characterized by similar oxidative stress and transsulfuration pathway abnormalities. |
2020-06-11 |
2023-08-13 |
Not clear |
| Reham Saeed Alsakhawi, Mohamed Ali Elshafe. Effect of Core Stability Exercises and Treadmill Training on Balance in Children with Down Syndrome: Randomized Controlled Trial. Advances in therapy. vol 36. issue 9. 2020-06-10. PMID:31301057. |
core stability exercises and treadmill training play a crucial role in physical therapy interventions and have an effect on balance in children with down syndrome (ds); however, whether core stability exercises or treadmill training has more effect on improving balance has not been investigated yet. |
2020-06-10 |
2023-08-13 |
Not clear |
| Clotilde Mircher, Silvia Sacco, Charles Bouis, Jennifer Gallard, Aude Pichot, Eric Le Galloudec, Cécile Cieuta, Isabelle Marey, Oliver Greiner-Mahler, Nathalie Dorison, Alicia Gambarini, Samantha Stora, Sophie Durand, Michel Polak, André Baruchel, Emilie Schlumberger, Jean Dewailly, Ahlam Azar-Kolakez, Rosa-Maria Guéant-Rodriguez, Jean-Louis Guéant, Didier Borderie, Dominique Bonnefont-Rousselot, Elodie Blondiaux, Aimé Ravel, Franck G Sturt. Thyroid hormone and folinic acid in young children with Down syndrome: the phase 3 ACTHYF trial. Genetics in medicine : official journal of the American College of Medical Genetics. vol 22. issue 1. 2020-06-08. PMID:31281181. |
to determine whether folinic acid (fa) and thyroxine, in combination or alone, benefit psychomotor development in young patients with down syndrome (ds). |
2020-06-08 |
2023-08-13 |
Not clear |
| Hélio José Coelho-Junior, Emanuele Rocco Villani, Riccardo Calvani, Angelo Carfì, Anna Picca, Francesco Landi, Roberto Bernabei, Graziano Onder, Emanuele Marzett. Sarcopenia-related parameters in adults with Down syndrome: A cross-sectional exploratory study. Experimental gerontology. vol 119. 2020-06-01. PMID:30710683. |
people with down syndrome (ds) experience premature aging. |
2020-06-01 |
2023-08-13 |
Not clear |
| Carolyn F Ross, Charles B Bernhard, Sarah Smith-Simpso. Parent-reported ease of eating foods of different textures in young children with Down syndrome. Journal of texture studies. vol 50. issue 5. 2020-06-01. PMID:31081543. |
food texture has been identified as a significant contributor to feeding problems in children, particularly in children with down syndrome (ds). |
2020-06-01 |
2023-08-13 |
Not clear |
| Gary E Martin, Jamie Barstein, Shivani Patel, Michelle Lee, Laura Henry, Molly Los. Longitudinal analysis of communication repair skills across three neurodevelopmental disabilities. International journal of language & communication disorders. vol 55. issue 1. 2020-06-01. PMID:31538707. |
this study is a longitudinal follow-up to prior work examining the important pragmatic skill of communication repair (i.e., the ability to respond effectively to a request for clarification of an unclear message) across three neurodevelopmental disabilities in which language skills are impaired: fragile x syndrome with and without autism spectrum disorder (fxs-asd; fxs-o), idiopathic asd (asd-o), down syndrome (ds) and controls with typical development (td). |
2020-06-01 |
2023-08-13 |
Not clear |
| V Simms, A Karmiloff-Smith, E Ranzato, J Van Herwege. Understanding Number Line Estimation in Williams Syndrome and Down Syndrome. Journal of autism and developmental disorders. vol 50. issue 2. 2020-06-01. PMID:31705420. |
previous studies suggest that tasks dependent on the mental number line may be difficult for williams syndrome (ws) and down syndrome (ds) groups. |
2020-06-01 |
2023-08-13 |
human |
| Sara K Trowbridge, Christopher J Yuskaitis, Nicole Baumer, Mark Libenson, Sanjay P Prabhu, Chellamani Harin. Brain MRI abnormalities in patients with infantile spasms and Down syndrome. Epilepsy & behavior : E&B. vol 92. 2020-05-25. PMID:30616066. |
infantile spasms (is) are the most frequent epilepsy syndrome in children with down syndrome (ds). |
2020-05-25 |
2023-08-13 |
Not clear |
| Benjamin I Laufer, Hyeyeon Hwang, Annie Vogel Ciernia, Charles E Mordaunt, Janine M LaSall. Whole genome bisulfite sequencing of Down syndrome brain reveals regional DNA hypermethylation and novel disorder insights. Epigenetics. vol 14. issue 7. 2020-05-20. PMID:31010359. |
down syndrome (ds) is the most common genetic cause of intellectual disability, in which an extra copy of human chromosome 21 (hsa21) affects regional dna methylation profiles across the genome. |
2020-05-20 |
2023-08-13 |
human |
| Colm R Breatnach, Neidin Bussmann, Aisling Smith, Phil Levy, Naomi McCallion, Orla Franklin, Afif El-Khuffas. Cardiac mechanics in infants with Down syndrome in the early neonatal period. Journal of perinatology : official journal of the California Perinatal Association. vol 39. issue 5. 2020-05-19. PMID:30911081. |
the objective of this study is to test whether myocardial performance is impaired over the first week of age in infants with down syndrome (ds) without congenital heart disease (chd). |
2020-05-19 |
2023-08-13 |
Not clear |
| Matteo Zago, Peter A Federolf, Shan R Levy, Claudia Condoluci, Manuela Gall. Down Syndrome: Gait Pattern Alterations in Posture Space Kinematics. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. vol 27. issue 8. 2020-05-18. PMID:31265404. |
gait characteristics in down syndrome (ds) are documented in terms of discrete kinematic variables. |
2020-05-18 |
2023-08-13 |
Not clear |
| Mônica da Consolação Canuto Salgueiro, Tamiris Silva, Lara Jansiski Motta, Anna Carolina Ratto Tempestini Horliana, Marcela Letícia Leal Gonçalves, Andréa Oliver Gomes, Marcelo Mendes Pinto, Carolina Carvalho Bortoletto, Olga Maria Altavista, Alessandro Melo Deana, Daniela de Fátima Teixeira da Silva, Elaine Marcilio Santos, Paula Midori Castelo, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Sandra Kalil Bussador. Effects of Photobiomodulation in Children with Down Syndrome and Possible Sleep Bruxism: Protocol For A Randomized, Controlled, Blind, Clinical Trial: Study protocol clinical trial (SPIRIT compliant). Medicine. vol 99. issue 17. 2020-05-11. PMID:32332670. |
hypotonia, particularly of the masticatory and oropharyngeal muscles, is 1 of the main characteristics of down syndrome (ds), resulting in impaired speech, chewing and swallowing. |
2020-05-11 |
2023-08-13 |
human |
| Carla M Startin, Nicholas J Ashton, Sarah Hamburg, Rosalyn Hithersay, Frances K Wiseman, Kin Y Mok, John Hardy, Alberto Lleó, Simon Lovestone, Lucilla Parnetti, Henrik Zetterberg, Abdul Hye, André Strydo. Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer's disease. Alzheimer's research & therapy. vol 11. issue 1. 2020-05-08. PMID:30902060. |
down syndrome (ds), caused by chromosome 21 trisomy, is associated with an ultra-high risk of dementia due to alzheimer's disease (ad), driven by amyloid precursor protein (app) gene triplication. |
2020-05-08 |
2023-08-13 |
Not clear |
| Lauren A Sarno, Henry L Walters, Igor Bondarenko, Ronald Thomas, Daisuke Kobayash. Significant Improvements in Mortality After the Fontan Operation in Children With Down Syndrome. The Annals of thoracic surgery. vol 109. issue 3. 2020-05-07. PMID:31525348. |
down syndrome (ds) is considered a risk factor for mortality associated with the fontan operation. |
2020-05-07 |
2023-08-13 |
Not clear |
| D Allan Butterfield, Debra Boyd-Kimbal. Redox proteomics and amyloid β-peptide: insights into Alzheimer disease. Journal of neurochemistry. vol 151. issue 4. 2020-05-04. PMID:30216447. |
in this review, we discuss these proteins in the context of those identified to be oxidatively modified in animal models of ad, and human studies including familial ad, pre-clinical ad (pcad), mild cognitive impairment (mci), early ad, late ad, down syndrome (ds), and ds with ad (ds/ad). |
2020-05-04 |
2023-08-13 |
human |
| Elijah Mak, Concepcion Padilla, Tiina Annus, Liam R Wilson, Young T Hong, Tim D Fryer, Jonathan P Coles, Franklin I Aigbirhio, David K Menon, Peter J Nestor, Shahid H Zaman, Anthony J Hollan. Delineating the topography of amyloid-associated cortical atrophy in Down syndrome. Neurobiology of aging. vol 80. 2020-04-30. PMID:31207551. |
older adults with down syndrome (ds) often have alzheimer's disease (ad) neuropathologies. |
2020-04-30 |
2023-08-13 |
Not clear |
| Paula Araya, Katherine A Waugh, Kelly D Sullivan, Nicolás G Núñez, Emiliano Roselli, Keith P Smith, Ross E Granrath, Angela L Rachubinski, Belinda Enriquez Estrada, Eric T Butcher, Ross Minter, Kathryn D Tuttle, Tullia C Bruno, Mariana Maccioni, Joaquín M Espinos. Trisomy 21 dysregulates T cell lineages toward an autoimmunity-prone state associated with interferon hyperactivity. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 48. 2020-04-27. PMID:31699819. |
trisomy 21 (t21) causes down syndrome (ds), a condition characterized by high prevalence of autoimmune disorders. |
2020-04-27 |
2023-08-13 |
Not clear |
| Keiichi Ishihara, Eri Kawashita, Ryohei Shimizu, Kazuki Nagasawa, Hiroyuki Yasui, Haruhiko Sago, Kazuhiro Yamakawa, Satoshi Akib. Copper accumulation in the brain causes the elevation of oxidative stress and less anxious behavior in Ts1Cje mice, a model of Down syndrome. Free radical biology & medicine. vol 134. 2020-04-21. PMID:30660502. |
elevated oxidative stress (os) is widely accepted to be involved in the pathogenesis of down syndrome (ds). |
2020-04-21 |
2023-08-13 |
mouse |
| Remi Bertran. Parents' perspective on having a child with Down Syndrome in France. American journal of medical genetics. Part A. vol 179. issue 5. 2020-04-21. PMID:30828960. |
in 2011, skotko, levine, and goldstein asked parents who had children with down syndrome (ds) in the united states how they felt about having a child with ds. |
2020-04-21 |
2023-08-13 |
Not clear |
| Arwen Jackson, Jennifer Maybee, Kristine Wolter-Warmerdam, Emily DeBoer, Francis Hicke. Associations between age, respiratory comorbidities, and dysphagia in infants with down syndrome. Pediatric pulmonology. vol 54. issue 11. 2020-04-21. PMID:31402588. |
children with down syndrome (ds) have a high risk of dysphagia and the pediatric pulmonologist may be involved in diagnosis and management. |
2020-04-21 |
2023-08-13 |
Not clear |