| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Geoffrey Pires, Sacha McElligott, Shiron Drusinsky, Glenda Halliday, Marie-Claude Potier, Thomas Wisniewski, Eleanor Drummon. Secernin-1 is a novel phosphorylated tau binding protein that accumulates in Alzheimer's disease and not in other tauopathies. Acta neuropathologica communications. vol 7. issue 1. 2020-09-25. PMID:31796108. |
scrn1 accumulation was also examined in two cases with both frontotemporal lobar degeneration (ftld)-tau and ad-related neuropathology, cases of down syndrome (ds) with ad (n = 5), one case of hereditary cerebral hemorrhage with amyloidosis - dutch type (hchwa-d) and other non-ad tauopathies including: primary age-related tauopathy (part, [n = 5]), corticobasal degeneration (cbd, [n = 5]), progressive supranuclear palsy (psp, [n = 5]) and pick's disease (pid, [n = 4]). |
2020-09-25 |
2023-08-13 |
human |
| Martina Penk. Regular and irregular inflection in down syndrome - New evidence from German. Cortex; a journal devoted to the study of the nervous system and behavior. vol 116. 2020-09-24. PMID:30249442. |
the study aims to explore whether regular inflectional morphology is affected in children/adolescents with down syndrome (ds). |
2020-09-24 |
2023-08-13 |
Not clear |
| Ellen M Schill, Christina M Wright, Alisha Jamil, Jonathan M LaCombe, Randall J Roper, Robert O Heuckerot. Down syndrome mouse models have an abnormal enteric nervous system. JCI insight. vol 5. 2020-09-24. PMID:30998504. |
children with trisomy 21 (down syndrome [ds]) have a 130-fold increased incidence of hirschsprung disease (hscr), a developmental defect where the enteric nervous system (ens) is missing from distal bowel (i.e., distal bowel is aganglionic). |
2020-09-24 |
2023-08-13 |
mouse |
| Eryse Amira Seth, Han-Chung Lee, Hadri Hadi Bin Md Yusof, Norshariza Nordin, Yoke Kqueen Cheah, Eric Tatt Wei Ho, King-Hwa Ling, Pike-See Chea. Phenotype microarrays reveal metabolic dysregulations of neurospheres derived from embryonic Ts1Cje mouse model of Down syndrome. PloS one. vol 15. issue 7. 2020-09-24. PMID:32730314. |
down syndrome (ds), is the most common cause of intellectual disability, and is characterized by defective neurogenesis during perinatal development. |
2020-09-24 |
2023-08-13 |
mouse |
| E A Pitchford, R E Hasson, J E Hornyak, J C Lumeng, K E Peterson, D A Ulric. Diurnal cortisol and obesity in adolescents with and without Down syndrome. Journal of intellectual disability research : JIDR. vol 63. issue 12. 2020-09-23. PMID:31441183. |
the prevalence of obesity in adolescents with down syndrome (ds) far exceeds that in the general population. |
2020-09-23 |
2023-08-13 |
Not clear |
| Pieter-Henk Boer, Zelda de Bee. The effect of aquatic exercises on the physical and functional fitness of adults with Down syndrome: A non-randomised controlled trial. Journal of intellectual disability research : JIDR. vol 63. issue 12. 2020-09-23. PMID:31468607. |
the importance of exercise for individuals with down syndrome (ds) has been well documented. |
2020-09-23 |
2023-08-13 |
Not clear |
| Mariana Perepitchka, Yekaterina Galat, Igor P Beletsky, Philip M Iannaccone, Vasiliy Gala. Down syndrome iPSC model: endothelial perspective on tumor development. Oncotarget. vol 11. issue 36. 2020-09-22. PMID:32934781. |
trisomy 21 (t21), known as down syndrome (ds), is a widely studied chromosomal abnormality. |
2020-09-22 |
2023-08-13 |
Not clear |
| Diego M Ferreira, Huaqing Liang, Jianhua W. Knee joint kinematics of the pendulum test in children with and without Down syndrome. Gait & posture. vol 76. 2020-09-21. PMID:31887704. |
the wartenberg pendulum test is a common clinical test that is used to measure stiffness about the knee in persons with and without disabilities such as cerebral palsy and down syndrome (ds). |
2020-09-21 |
2023-08-13 |
Not clear |
| E K Choi, E Jung, M Van Riper, Y J Le. Sleep problems in Korean children with Down syndrome and parental quality of life. Journal of intellectual disability research : JIDR. vol 63. issue 11. 2020-09-17. PMID:31353681. |
sleep problems are common among children with down syndrome (ds), and they can have a serious impact on children with ds as well as their parents and other family members. |
2020-09-17 |
2023-08-13 |
Not clear |
| Hassan Hashemi, Ali Makateb, Shiva Mehravaran, Akbar Fotouhi, Fereshteh Shariati, Soheila Asgar. Mapping the corneal thickness and volume in patients with Down syndrome: a comparative population-based study. Arquivos brasileiros de oftalmologia. vol 83. issue 3. 2020-09-17. PMID:32490977. |
to measure the central-to-peripheral corneal thickness and its volume according to age and gender in 10-30-year-old patients with down syndrome (ds) and in matched individuals without ds. |
2020-09-17 |
2023-08-13 |
Not clear |
| David Sánchez-Teruel, María Auxiliadora Robles-Bello, José Antonio Camacho-Cond. Assessment of emotional intelligence in adults with down syndrome: Psychometric properties of the Emotional Quotient Inventory. PloS one. vol 15. issue 7. 2020-09-17. PMID:32697810. |
traditionally, research in down syndrome (ds) has focused on identifying cognitive deficits, relatively little is known about emotional intelligence (ei) and there are no scales that measure ei in people with ds adults. |
2020-09-17 |
2023-08-13 |
Not clear |
| Michael S Rafii, Michael C Donohue, Dawn C Matthews, Gabriela Muranevici, Seth Ness, Sid E O'Bryant, Robert A Rissma. Plasma Neurofilament Light and Alzheimer's Disease Biomarkers in Down Syndrome: Results from the Down Syndrome Biomarker Initiative (DSBI). Journal of Alzheimer's disease : JAD. vol 70. issue 1. 2020-09-16. PMID:31156181. |
adults with down syndrome (ds) are at very high risk for alzheimer's disease (ad). |
2020-09-16 |
2023-08-13 |
Not clear |
| Katherine A Waugh, Paula Araya, Ahwan Pandey, Kimberly R Jordan, Keith P Smith, Ross E Granrath, Santosh Khanal, Eric T Butcher, Belinda Enriquez Estrada, Angela L Rachubinski, Jennifer A McWilliams, Ross Minter, Tiana Dimasi, Kelley L Colvin, Dmitry Baturin, Andrew T Pham, Matthew D Galbraith, Kyle W Bartsch, Michael E Yeager, Christopher C Porter, Kelly D Sullivan, Elena W Hsieh, Joaquin M Espinos. Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome. Cell reports. vol 29. issue 7. 2020-09-16. PMID:31722205. |
people with down syndrome (ds; trisomy 21) display a different disease spectrum relative to the general population, including lower rates of solid malignancies and higher incidence of neurological and autoimmune conditions. |
2020-09-16 |
2023-08-13 |
Not clear |
| Michael V Fedewa, Angela R Russell, Brett S Nickerson, Megan P Fedewa, John W Myrick, Michael R Esc. Relative accuracy of body adiposity index and relative fat mass in participants with and without down syndrome. European journal of clinical nutrition. vol 73. issue 8. 2020-09-14. PMID:30337713. |
there is limited research validating these methods of body composition assessment in adults with down syndrome (ds). |
2020-09-14 |
2023-08-13 |
human |
| Claudio Franceschi, Paolo Garagnani, Noémie Gensous, Maria Giulia Bacalini, Maria Conte, Stefano Salviol. Accelerated bio-cognitive aging in Down syndrome: State of the art and possible deceleration strategies. Aging cell. vol 18. issue 3. 2020-09-14. PMID:30768754. |
down syndrome (ds) has been proposed by george martin as a segmental progeroid syndrome since 1978. |
2020-09-14 |
2023-08-13 |
Not clear |
| Monika Zbucka-Kretowska, Magdalena Niemira, Magdalena Paczkowska-Abdulsalam, Agnieszka Bielska, Anna Szalkowska, Ewa Parfieniuk, Michal Ciborowski, Slawomir Wolczynski, Adam Kretowsk. Prenatal circulating microRNA signatures of foetal Down syndrome. Scientific reports. vol 9. issue 1. 2020-09-14. PMID:30787377. |
the aim of the study was to determine the expression level of mirnas in plasma of pregnant women with foetal down syndrome (ds). |
2020-09-14 |
2023-08-13 |
Not clear |
| Ruma Raha-Chowdhury, James W Henderson, Animesh Alexander Raha, Romina Vuono, Anastasia Bickerton, Elizabeth Jones, Robert Fincham, Kieren Allinson, Anthony Holland, Shahid H Zama. Choroid Plexus Acts as Gatekeeper for TREM2, Abnormal Accumulation of ApoE, and Fibrillary Tau in Alzheimer's Disease and in Down Syndrome Dementia. Journal of Alzheimer's disease : JAD. vol 69. issue 1. 2020-09-09. PMID:30909239. |
genetic factors that influence alzheimer's disease (ad) risk include mutations in trem2 and allelic variants of apolipoprotein e, influencing ad pathology in the general population and in down syndrome (ds). |
2020-09-09 |
2023-08-13 |
Not clear |
| J Y M Tang, H Luo, G H Y Wong, M M Y Lau, G M Joe, M A Tse, P Ip, I C K Wong, T Y S Lu. Bone mineral density from early to middle adulthood in persons with Down syndrome. Journal of intellectual disability research : JIDR. vol 63. issue 8. 2020-09-08. PMID:30775821. |
while accelerated ageing is recognised among individuals with down syndrome (ds), the trajectory of their bone health across adulthood remains poorly understood. |
2020-09-08 |
2023-08-13 |
Not clear |
| C S Musaeus, L C Salem, A Sabers, T W Kjaer, G Waldema. Associations between electroencephalography power and Alzheimer's disease in persons with Down syndrome. Journal of intellectual disability research : JIDR. vol 63. issue 9. 2020-09-08. PMID:31025465. |
it is complicated to diagnose dementia in persons with down syndrome (ds). |
2020-09-08 |
2023-08-13 |
Not clear |
| E McGlinchey, M McCarron, A Holland, P McCallio. Examining the effects of computerised cognitive training on levels of executive function in adults with Down syndrome. Journal of intellectual disability research : JIDR. vol 63. issue 9. 2020-09-08. PMID:31062455. |
individuals with down syndrome (ds) are at much greater risk of developing alzheimer's disease, and one of the early clinical symptoms of alzheimer's disease is executive dysfunction. |
2020-09-08 |
2023-08-13 |
Not clear |