| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mathilde Bostelmann, Floriana Costanzo, Lorelay Martorana, Deny Menghini, Stefano Vicari, Pamela Banta Lavenex, Pierre Lavene. Low-Resolution Place and Response Learning Capacities in Down Syndrome. Frontiers in psychology. vol 9. 2020-09-30. PMID:30416470. |
down syndrome (ds), the most common genetic cause of intellectual disability, results from the partial or complete triplication of chromosome 21. |
2020-09-30 |
2023-08-13 |
Not clear |
| Diamond Ling, Jonathan G Daya. In Utero Diagnoses of Strikingly Similar Presentations of Complete Atrioventricular Septal Defects in a Pair of Dizygotic Twins Concordant for Trisomy 21. Case reports in pediatrics. vol 2018. 2020-09-30. PMID:30416835. |
trisomy 21, or down syndrome (ds), is a genetic disorder affecting approximately 1 in 500-750 live births. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ines A Basten, Richard Boada, Hudson G Taylor, Katherine Koenig, Veridiana L Barrionuevo, Ana C Brandão, Alberto C S Cost. On the Design of Broad-Based Neuropsychological Test Batteries to Assess the Cognitive Abilities of Individuals with Down Syndrome in the Context of Clinical Trials. Brain sciences. vol 8. issue 12. 2020-09-30. PMID:30486228. |
down syndrome (ds) is the most common genetically-defined cause of intellectual disability. |
2020-09-30 |
2023-08-13 |
mouse |
| Maryam Rabiee, Zahra Jouhari, Ashraf Piraste. Knowledge of Prenatal Screening, Down Syndrome, Amniocentesis, and Related Factors among Iranian Pregnant Women: A Cross-Sectional Study. International journal of community based nursing and midwifery. vol 7. issue 2. 2020-09-30. PMID:31041325. |
the primary goal of prenatal aneuploidy screening is the early detection of pregnancies at high risk of down syndrome (ds). |
2020-09-30 |
2023-08-13 |
Not clear |
| Andrea Giacomini, Fiorenza Stagni, Marco Emili, Beatrice Uguagliati, Roberto Rimondini, Renata Bartesaghi, Sandra Guid. Timing of Treatment with the Flavonoid 7,8-DHF Critically Impacts on Its Effects on Learning and Memory in the Ts65Dn Mouse. Antioxidants (Basel, Switzerland). vol 8. issue 6. 2020-09-30. PMID:31174258. |
no therapies currently exist for intellectual disability in down syndrome (ds). |
2020-09-30 |
2023-08-13 |
mouse |
| Malakooti N, Fowler C, Volitakis I, McLean Ca, Kim Rc, Bush Ai, Rembach A, Pritchard Ma, Finkelstein DI, Adlard P. The Down Syndrome-Associated Protein, Regulator of Calcineurin-1, is Altered in Alzheimer's Disease and Dementia with Lewy Bodies. Journal of Alzheimer's disease & Parkinsonism. vol 9. issue 2. 2020-09-30. PMID:31263630. |
there is a known relationship between alzheimer's disease (ad) and down syndrome (ds), with the latter typically developing ad-like neuropathology in mid-life. |
2020-09-30 |
2023-08-13 |
Not clear |
| Anna Joyce, Heather Elphick, Michael Farquhar, Paul Gringras, Hazel Evans, Romola S Bucks, Jana Kreppner, Ruth Kingshott, Jane Martin, Janine Reynolds, Carla Rush, Johanna Gavlak, Catherine M Hil. Obstructive Sleep Apnoea Contributes to Executive Function Impairment in Young Children with Down Syndrome. Behavioral sleep medicine. vol 18. issue 5. 2020-09-30. PMID:31311334. |
children with down syndrome (ds) commonly experience difficulties with executive function (ef). |
2020-09-30 |
2023-08-13 |
Not clear |
| Nada AlAaraj, Ashraf T Soliman, Maya Itani, Ahmed Khalil, Vincenzo De Sancti. Prevalence of thyroid dysfunctions in infants and children with Down Syndrome (DS) and the effect of thyroxine treatment on linear growth and weight gain in treated subjects versus DS subjects with normal thyroid function: a controlled study. Acta bio-medica : Atenei Parmensis. vol 90. issue 8-S. 2020-09-30. PMID:31544805. |
prevalence of thyroid dysfunctions in infants and children with down syndrome (ds) and the effect of thyroxine treatment on linear growth and weight gain in treated subjects versus ds subjects with normal thyroid function: a controlled study. |
2020-09-30 |
2023-08-13 |
human |
| Nada AlAaraj, Ashraf T Soliman, Maya Itani, Ahmed Khalil, Vincenzo De Sancti. Prevalence of thyroid dysfunctions in infants and children with Down Syndrome (DS) and the effect of thyroxine treatment on linear growth and weight gain in treated subjects versus DS subjects with normal thyroid function: a controlled study. Acta bio-medica : Atenei Parmensis. vol 90. issue 8-S. 2020-09-30. PMID:31544805. |
individuals with down syndrome (ds) are at an increased risk of developing thyroid disease, primarily autoimmune, with a lifetime prevalence ranging from 13% to 63%. |
2020-09-30 |
2023-08-13 |
human |
| Tiffany J Glass, Luke Carmichael V Valmadrid, Nadine P Conno. The Adult Ts65Dn Mouse Model of Down Syndrome Shows Altered Swallow Function. Frontiers in neuroscience. vol 13. 2020-09-30. PMID:31555077. |
there are increased risks for deglutition disorders in people with down syndrome (ds). |
2020-09-30 |
2023-08-13 |
mouse |
| Alessandra Maria Adelaide Chiotto, Martina Migliorero, Gianmarco Pallavicini, Federico Tommaso Bianchi, Marta Gai, Ferdinando Di Cunto, Gaia Elena Bert. Neuronal Cell-Intrinsic Defects in Mouse Models of Down Syndrome. Frontiers in neuroscience. vol 13. 2020-09-30. PMID:31649502. |
down syndrome (ds) is the most common genetic disorder associated with intellectual disability (id). |
2020-09-30 |
2023-08-13 |
mouse |
| Paul M Mathews, Efrat Lev. Exosome Production Is Key to Neuronal Endosomal Pathway Integrity in Neurodegenerative Diseases. Frontiers in neuroscience. vol 13. 2020-09-30. PMID:31911768. |
we and others have extensively characterized the neuronal endosomal pathway pathology that results from either triplication of the amyloid-β precursor protein (app) gene in down syndrome (ds) or from expression of the apolipoprotein e ε4 allele (apoe4), the greatest genetic risk factor for late-onset ad. |
2020-09-30 |
2023-08-13 |
Not clear |
| Joo-Ho Shin, Jae-Won Yang, Marie Le Pecheur, Jacqueline London, Harald Hoeger, Gert Lube. Altered expression of hypothetical proteins in hippocampus of transgenic mice overexpressing human Cu/Zn-superoxide dismutase 1. Proteome science. vol 2. issue 1. 2020-09-29. PMID:15193154. |
background: cu/zn-superoxide dismutase 1 (sod1), encoded on chromosome 21, is a key enzyme in the metabolism of reactive oxygen species (ros) and pathogenetically relevant for several disease states including down syndrome (ds; trisomy 21). |
2020-09-29 |
2023-08-12 |
mouse |
| Kelly Burgoyne, Fiona J Duff, Dea Nielsen, Anastasia Ulicheva, Margaret J Snowlin. Bilingualism and Biliteracy in Down Syndrome: Insights From a Case Study. Language learning. vol 66. issue 4. 2020-09-29. PMID:27917003. |
we present the case study of mb-a bilingual child with down syndrome (ds) who speaks russian (first language [l1]) and english (second language [l2]) and has learned to read in two different alphabets with different symbol systems. |
2020-09-29 |
2023-08-13 |
Not clear |
| Arianna Bentenuto, Simona De Falco, Paola Venut. Mother-Child Play: A Comparison of Autism Spectrum Disorder, Down Syndrome, and Typical Development. Frontiers in psychology. vol 7. 2020-09-29. PMID:27920745. |
the purpose of the present study was to analyze mother-child collaborative play in children with autism spectrum disorders (asd) compared to children with down syndrome (ds) and typical developing children (td). |
2020-09-29 |
2023-08-13 |
human |
| Mohammad Kazemi, Mansoor Salehi, Majid Kheirollah. Down Syndrome: Current Status, Challenges and Future Perspectives. International journal of molecular and cellular medicine. vol 5. issue 3. 2020-09-29. PMID:27942498. |
down syndrome (ds) is a birth defect with huge medical and social costs, caused by trisomy of whole or part of chromosome 21. |
2020-09-29 |
2023-08-13 |
Not clear |
| Hyo In Kim, Seong Woo Kim, Jiyong Kim, Ha Ra Jeon, Da Wa Jun. Motor and Cognitive Developmental Profiles in Children With Down Syndrome. Annals of rehabilitation medicine. vol 41. issue 1. 2020-09-29. PMID:28289641. |
to investigate motor and cognitive developmental profiles and to evaluate the correlation between two developmental areas and assess the influencing factors of the developmental process in children with down syndrome (ds). |
2020-09-29 |
2023-08-13 |
Not clear |
| Andrea Contestabile, Salvatore Magara, Laura Cancedd. The GABAergic Hypothesis for Cognitive Disabilities in Down Syndrome. Frontiers in cellular neuroscience. vol 11. 2020-09-29. PMID:28326014. |
down syndrome (ds) is a genetic disorder caused by the presence of a third copy of chromosome 21. |
2020-09-29 |
2023-08-13 |
mouse |
| Aldina Brás, António S Rodrigues, Bruno Gomes, José Ruef. Down syndrome and microRNAs. Biomedical reports. vol 8. issue 1. 2020-09-29. PMID:29403643. |
down syndrome (ds) is the most prevalent survivable chromosomal disorder and is attributed to trisomy 21 and the subsequent alteration of the dosage of genes located on this chromosome. |
2020-09-29 |
2023-08-13 |
human |
| Ahmad S Aly, Mohamed A Al-Kers. Femoral and Dega osteotomies in the treatment of habitual hip dislocation in Down syndrome patients - is it efficient or not? Journal of children's orthopaedics. vol 12. issue 3. 2020-09-29. PMID:29951121. |
the purpose of this case series study is to report on the intermediate-term outcomes following a femoral varus derotational osteotomy (fvdo) performed in conjunction with a dega osteotomy (do) in management of hip -instability in down syndrome (ds) patients. |
2020-09-29 |
2023-08-13 |
Not clear |