| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anis Feki, Youssef Hibaou. DYRK1A Protein, A Promising Therapeutic Target to Improve Cognitive Deficits in Down Syndrome. Brain sciences. vol 8. issue 10. 2020-09-29. PMID:30332747. |
down syndrome (ds) caused by a trisomy of chromosome 21 (hsa21), is the most common genetic developmental disorder, with an incidence of 1 in 800 live births. |
2020-09-29 |
2023-08-13 |
Not clear |
| Emily Lorang, Audra Sterlin. The impact of autism spectrum disorder symptoms on gesture use in fragile X syndrome and Down syndrome. Autism & developmental language impairments. vol 2. 2020-09-29. PMID:30345371. |
this study compared gesture rate and purpose in participants with down syndrome (ds) and fragile x syndrome (fxs), and the impact of autism spectrum disorder (asd) symptoms on each syndrome. |
2020-09-29 |
2023-08-13 |
human |
| Roger H Reeves, Jean Delabar, Marie-Claude Potier, Anita Bhattacharyya, Elizabeth Head, Cynthia Lemere, Alain D Dekker, Peter De Deyn, Pablo Caviedes, Mara Dierssen, Jorge Buscigli. Paving the Way for Therapy: The Second International Conference of the Trisomy 21 Research Society. Molecular syndromology. vol 9. issue 6. 2020-09-29. PMID:30800043. |
in the last decade, a number of important research advances in different fields have allowed down syndrome (ds) research to flourish, creating a time of both unparalleled opportunity and considerable challenge. |
2020-09-29 |
2023-08-13 |
Not clear |
| Claudio Gallo, Irene Pastore, Marta Beghetto, Carla Mucignat-Carett. Symmetry of dental agenesis in Down Syndrome children. Journal of dental sciences. vol 14. issue 1. 2020-09-29. PMID:30988881. |
down syndrome (ds) may affect the mouth, influencing its function, feeding and hence overall health status. |
2020-09-29 |
2023-08-13 |
Not clear |
| Batool Ghaith, Manal Al Halabi, Amar Hassan Khamis, Mawlood Kowas. Oral Health Status among Children with Down Syndrome in Dubai, United Arab Emirates. Journal of International Society of Preventive & Community Dentistry. vol 9. issue 3. 2020-09-29. PMID:31198694. |
the purpose of this study was to assess the oral health status in down syndrome (ds) children in dubai, united arab emirates. |
2020-09-29 |
2023-08-13 |
Not clear |
| Keiichi Ishihara, Ryohei Shimizu, Kazuyuki Takata, Eri Kawashita, Kenji Amano, Atsushi Shimohata, Donovan Low, Takeshi Nabe, Haruhiko Sago, Warren S Alexander, Florent Ginhoux, Kazuhiro Yamakawa, Satoshi Akib. Perturbation of the immune cells and prenatal neurogenesis by the triplication of the Erg gene in mouse models of Down syndrome. Brain pathology (Zurich, Switzerland). vol 30. issue 1. 2020-09-29. PMID:31206867. |
some mouse models of down syndrome (ds), including ts1cje mice, exhibit impaired prenatal neurogenesis with yet unknown molecular mechanism. |
2020-09-29 |
2023-08-13 |
mouse |
| Christopher A Hargunani, Ericka King, Henry A Milczuk, Carol J MacArthu. Endoscopic ear surgery in children with down syndrome. International journal of pediatric otorhinolaryngology. vol 131. 2020-09-29. PMID:31972386. |
children with down syndrome (ds) have a high incidence of chronic middle ear disease. |
2020-09-29 |
2023-08-13 |
Not clear |
| Patrick J Lao, Ben L Handen, Tobey J Betthauser, Iulia Mihaila, Sigan L Hartley, Annie D Cohen, Dana L Tudorascu, Peter D Bulova, Brian J Lopresti, Rameshwari V Tumuluru, Dhanabalan Murali, Chester A Mathis, Todd E Barnhart, Charles K Stone, Julie C Price, Darlynne A Devenny, Marsha R Mailick, William E Klunk, Sterling C Johnson, Bradley T Christia. Longitudinal changes in amyloid positron emission tomography and volumetric magnetic resonance imaging in the nondemented Down syndrome population. Alzheimer's & dementia (Amsterdam, Netherlands). vol 9. 2020-09-28. PMID:28603769. |
down syndrome (ds) arises from a triplication of chromosome 21, causing overproduction of the amyloid precursor protein and predisposes individuals to early alzheimer's disease (ad). |
2020-09-28 |
2023-08-13 |
Not clear |
| Cláudia Melo de Moura, Pedro Ribeiro Bastos, Julyana S V Ribeiro, Márcia Gonçalves Ribeiro, Márcia Rodrigues Amorim, Marcelo Aguiar Costa-Lim. DNA (cytosine-5)-methyltransferase 3B ( Saudi journal of biological sciences. vol 25. issue 1. 2020-09-28. PMID:29379364. |
dna (cytosine-5)-methyltransferase 3b ( down syndrome (ds) is the most common form of human genetic mental retardation. |
2020-09-28 |
2023-08-13 |
human |
| May Salem Al-Nbahee. Analysis of Downs syndrome with molecular techniques for future diagnoses. Saudi journal of biological sciences. vol 25. issue 3. 2020-09-28. PMID:29686519. |
down syndrome (ds) is a genetic disorder appeared due to the presence of trisomy in chromosome 21 in the g-group of the acrocentric region. |
2020-09-28 |
2023-08-13 |
human |
| Ming-Yu Liu, Cheng-Ting Lee, Ni-Chung Lee, Yi-Ching Tung, Yin-Hsiu Chien, Wuh-Liang Hwu, Wen-Yu Tsa. Thyroid disorders in Taiwanese children with Down syndrome: The experience of a single medical center. Journal of the Formosan Medical Association = Taiwan yi zhi. vol 119. issue 1 Pt 2. 2020-09-28. PMID:31255418. |
thyroid disorders are common in children with down syndrome (ds), however, such data have rarely been reported in taiwanese children. |
2020-09-28 |
2023-08-13 |
Not clear |
| Nunzia Mollo, Maria Nitti, Lucrezia Zerillo, Deriggio Faicchia, Teresa Micillo, Rossella Accarino, Agnese Secondo, Tiziana Petrozziello, Gaetano Calì, Rita Cicatiello, Ferdinando Bonfiglio, Viviana Sarnataro, Rita Genesio, Antonella Izzo, Paolo Pinton, Giuseppe Matarese, Simona Paladino, Anna Conti, Lucio Nitsc. Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells. Frontiers in genetics. vol 10. 2020-09-28. PMID:31316549. |
mitochondrial dysfunction plays a primary role in neurodevelopmental anomalies and neurodegeneration of down syndrome (ds) subjects. |
2020-09-28 |
2023-08-13 |
human |
| Andrea Sechi, Alba Guglielmo, Annalisa Patrizi, Francesco Savoia, Guido Cocchi, Miriam Leuzzi, Marco A Chess. Disseminate Recurrent Folliculitis and Hidradenitis Suppurativa Are Associated Conditions: Results From a Retrospective Study of 131 Patients With Down Syndrome and a Cohort of 12,351 Pediatric Controls. Dermatology practical & conceptual. vol 9. issue 3. 2020-09-28. PMID:31384491. |
patients with down syndrome (ds) have a higher risk of developing a wide range of cutaneous manifestations, including hs and chronic folliculitis. |
2020-09-28 |
2023-08-13 |
Not clear |
| Jue Seong Lee, Seul Gi Cha, Gi Beom Kim, Sang Yun Lee, Mi Kyoung Song, Hye Won Kwon, Eun Jung Bae, Jae Gun Kwak, Woong Han Kim, Jeong Ryul Le. Reversibility of Pulmonary Hypertension Following Surgical Atrial Septal Defect Closure in Children with Down Syndrome. Journal of cardiovascular imaging. vol 27. issue 4. 2020-09-28. PMID:31614394. |
many down syndrome (ds) patients have an atrial septal defect (asd) and associated pulmonary hypertension (ph) from early childhood. |
2020-09-28 |
2023-08-13 |
Not clear |
| Edward Charbek, Ghassan Kamel, Ravi P Naya. Ivacaftor for the Treatment of Cystic Fibrosis Coexisting with Trisomy 21: A Case Report. Cureus. vol 11. issue 11. 2020-09-28. PMID:31890385. |
the association between cystic fibrosis (cf) and trisomy 21, or down syndrome (ds) is rare, and it pertains a poor prognosis with the majority of patients dying in infancy. |
2020-09-28 |
2023-08-13 |
Not clear |
| Carmen Martínez-Cué, Noemí Rued. Cellular Senescence in Neurodegenerative Diseases. Frontiers in cellular neuroscience. vol 14. 2020-09-28. PMID:32116562. |
there is an extensive body of literature that associates cellular senescence with several neurodegenerative disorders including alzheimer's disease (ad), down syndrome (ds), and parkinson's disease (pd). |
2020-09-28 |
2023-08-13 |
Not clear |
| E C Jenkins, L Ye, E Marchi, S J Krinsky-McHale, W B Zigman, N Schupf, W P Silverma. An improved method for detecting telomere size differences in T-lymphocyte interphases from older people with Down syndrome with and without mild cognitive impairment. Biology methods & protocols. vol 2. issue 1. 2020-09-28. PMID:32161788. |
telomere size (quantified by fluorescence intensity and physical lengths) in short-term t-lymphocyte cultures from adults with down syndrome (ds) with and without mild cognitive impairment (mci-ds) or dementia was compared. |
2020-09-28 |
2023-08-13 |
Not clear |
| Dean Huggard, Derek G Doherty, Eleanor J Mollo. Immune Dysregulation in Children With Down Syndrome. Frontiers in pediatrics. vol 8. 2020-09-28. PMID:32175298. |
down syndrome (ds) is the most common genetic syndrome associated with immune defects. |
2020-09-28 |
2023-08-13 |
Not clear |
| Giovanni Mento, Gaia Scerif, Umberto Granziol, Malida Franzoi, Silvia Lanfranch. The Effect of Probabilistic Context on Implicit Temporal Expectations in Down Syndrome. Frontiers in psychology. vol 11. 2020-09-28. PMID:32210885. |
in order to better understand the nature of local-global proactive motor control in down syndrome, in the present study a group of participants with down syndrome (ds group; |
2020-09-28 |
2023-08-13 |
human |
| Chiara Meneghetti, Enrico Toffalini, Silvia Lanfranchi, Barbara Carrett. Path Learning in Individuals With Down Syndrome: The Floor Matrix Task and the Role of Individual Visuo-Spatial Measures. Frontiers in human neuroscience. vol 14. 2020-09-28. PMID:32296317. |
in individuals with down syndrome (ds), this skill has begun to be examined using virtual exploration. |
2020-09-28 |
2023-08-13 |
human |