| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Allison Buterbaugh, Henry J Mroczkowski, Suma P Shankar, Jeannie Visootsa. Contribution of Family History in Co-occurring Down Syndrome and Ehlers-Danlos Syndrome. Annals of paediatric rheumatology. vol 2. issue 4. 2021-10-21. PMID:24839582. |
nearly all children with down syndrome (ds) are born with hypotonia which later improves with age. |
2021-10-21 |
2023-08-13 |
Not clear |
| Elizabeth Head, David Powell, Brian T Gold, Frederick A Schmit. Alzheimer's Disease in Down Syndrome. European journal of neurodegenerative disease. vol 1. issue 3. 2021-10-21. PMID:25285303. |
a key challenge to adults with down syndrome (ds) as they age is an increased risk for cognitive decline, dementia, and alzheimer disease (ad). |
2021-10-21 |
2023-08-13 |
Not clear |
| Allison Buterbaugh, Jeannie Visootsa. Implications of delayed diagnosis of infantile spasm in a child with Down syndrome. Journal of pediatric neurology : JPN. vol 12. issue 2. 2021-10-21. PMID:25309120. |
trisomy 21, leading to down syndrome (ds) is the most common genetic cause of intellectual disability. |
2021-10-21 |
2023-08-13 |
Not clear |
| Maria A Gartstein, Julia Marmion, Heather L Swanso. Infant Temperament: An Evaluation of Children with Down Syndrome. Journal of reproductive and infant psychology. vol 24. 2021-10-20. PMID:18354741. |
the current study investigated differences in the development of temperament for normally developing infants and infants with down syndrome (ds). |
2021-10-20 |
2023-08-12 |
Not clear |
| Anna J Esbense. Health conditions associated with aging and end of life of adults with Down syndrome. International review of research in mental retardation. vol 39. issue C. 2021-10-20. PMID:21197120. |
expectations for the life course of individuals with down syndrome (ds) have changed, with life expectancy estimates increasing from 12 in 1949 to nearly 60 years of age today (bittles & glasson, 2004; penrose, 1949). |
2021-10-20 |
2023-08-12 |
Not clear |
| Jamie O Edgin, Gina M Mason, Melissa J Allman, George T Capone, Iser Deleon, Cheryl Maslen, Roger H Reeves, Stephanie L Sherman, Lynn Nade. Development and validation of the Arizona Cognitive Test Battery for Down syndrome. Journal of neurodevelopmental disorders. vol 2. issue 3. 2021-10-20. PMID:21274406. |
to meet this need, the arizona cognitive test battery (actb) has been developed specifically to assess the cognitive phenotype in down syndrome (ds). |
2021-10-20 |
2023-08-12 |
human |
| Bruno Estigarribia, Gary E Martin, Joanne E Roberts, Amy Spencer, Agnieszka Gucwa, John Sideri. Narrative Skill in Boys with Fragile X Syndrome with and without Autism Spectrum Disorder. Applied psycholinguistics. vol 32. issue 2. 2021-10-20. PMID:21516264. |
we examined recalled narratives of boys with fragile x syndrome with autism spectrum disorder (fxs-asd; n=28) and without asd (fxs-o; n=29), and compared them to those of boys with down syndrome (ds; n=33) and typically developing boys (td; n=39). |
2021-10-20 |
2023-08-12 |
Not clear |
| Francis M Hacker, Alyssa R Hersh, Brian L Shaffer, Aaron B Caughe. Isolated echogenic intracardiac foci and the role of cell-free fetal DNA: A cost-effectiveness analysis. Prenatal diagnosis. vol 40. issue 12. 2021-10-20. PMID:32716062. |
cell-free fetal dna (cfdna) has been increasingly incorporated into prenatal aneuploidy screening paradigms given its relatively high sensitivity for down syndrome (ds). |
2021-10-20 |
2023-08-13 |
Not clear |
| Akane B Fujimoto, Turgay Ayer, Aaron B Caughey, Pinar Keskinoca. A comparison of first trimester prenatal screening strategies for Down Syndrome with maternal age and preferences considerations. Prenatal diagnosis. vol 40. issue 12. 2021-10-20. PMID:32794316. |
screening for down syndrome (ds) includes traditional ultrasound and serum-based and cell-free dna (cfdna) testing. |
2021-10-20 |
2023-08-13 |
Not clear |
| Eleonore Bayen, Kristine Yaffe, Laurent Cleret de Langavant, Yingjia Chen, Katherine L Possi. The direct health care cost to Medicare of Down syndrome dementia as compared with Alzheimer's disease among 2015 Californian beneficiaries. Annals of physical and rehabilitation medicine. vol 64. issue 1. 2021-10-20. PMID:32853759. |
aging individuals with down syndrome (ds) are at increased risk of dementia due to trisomy of chromosome 21 on which the amyloid precursor protein gene is located and with increased life expectancy. |
2021-10-20 |
2023-08-13 |
Not clear |
| Genni Enza Marcovecchio, Francesca Ferrua, Elena Fontana, Stefano Beretta, Marco Genua, Ileana Bortolomai, Anastasia Conti, Davide Montin, Maria Teresa Cascarano, Sonia Bergante, Veronica D'Oria, Alessandro Giamberti, Donato Amodio, Caterina Cancrini, Adriano Carotti, Raffaella Di Micco, Ivan Merelli, Marita Bosticardo, Anna Vill. Premature Senescence and Increased Oxidative Stress in the Thymus of Down Syndrome Patients. Frontiers in immunology. vol 12. 2021-10-20. PMID:34140950. |
down syndrome (ds) patients prematurely show clinical manifestations usually associated with aging. |
2021-10-20 |
2023-08-13 |
human |
| Maria Contaldo, Alberta Lucchese, Antonio Romano, Fedora Della Vella, Dario Di Stasio, Rosario Serpico, Massimo Petruzz. Oral Microbiota Features in Subjects with Down Syndrome and Periodontal Diseases: A Systematic Review. International journal of molecular sciences. vol 22. issue 17. 2021-10-20. PMID:34502159. |
down syndrome (ds) is a genetic disorder associated with early-onset periodontitis and other periodontal diseases (pds). |
2021-10-20 |
2023-08-13 |
human |
| Maria Contaldo, Alberta Lucchese, Antonio Romano, Fedora Della Vella, Dario Di Stasio, Rosario Serpico, Massimo Petruzz. Oral Microbiota Features in Subjects with Down Syndrome and Periodontal Diseases: A Systematic Review. International journal of molecular sciences. vol 22. issue 17. 2021-10-20. PMID:34502159. |
the participants were subjects affected by down syndrome (ds) with and without periodontal diseases; the study compared subjects with periodontal diseases but not affected by ds, and ds without periodontal diseases; the outcomes were the differences in oral microbiota/periodontopathogen bacterial composition among subjects considered; the study design was a systematic review. |
2021-10-20 |
2023-08-13 |
human |
| Reiko Iwano, Machiko Toki, Junko Hanakawa, Yumi Asakura, Masanori Adachi, Yukichi Tanaka, Koji Muroy. Quantification of serum thyroid hormones using tandem mass spectrometry in patients with Down syndrome. Biomedical chromatography : BMC. 2021-10-20. PMID:34569083. |
thyroid dysfunction is common in patients with down syndrome (ds), the most common chromosomal disorder. |
2021-10-20 |
2023-08-13 |
Not clear |
| M S Rafii, S Zaman, B L Hande. Integrating Biomarker Outcomes into Clinical Trials for Alzheimer's Disease in Down Syndrome. The journal of prevention of Alzheimer's disease. vol 8. issue 1. 2021-10-19. PMID:33336224. |
the nih-funded alzheimer's biomarker consortium down syndrome (abc-ds) and the european horizon 21 consortium are collecting critical new information on the natural history of alzheimer's disease (ad) biomarkers in adults with down syndrome (ds), a population genetically predisposed to developing ad. |
2021-10-19 |
2023-08-13 |
Not clear |
| M S Rafii, S Zaman, B L Hande. Integrating Biomarker Outcomes into Clinical Trials for Alzheimer's Disease in Down Syndrome. The journal of prevention of Alzheimer's disease. vol 8. issue 1. 2021-10-19. PMID:33336224. |
the alzheimer's clinical trial consortium - down syndrome (actc-ds) is a platform that brings expert researchers from both networks together to conduct clinical trials for ad in ds across international sites while building on their expertise and experience. |
2021-10-19 |
2023-08-13 |
Not clear |
| M Matthijs Fockens, Michiel Hölscher, Jacqueline Limpens, Frederik G Dikker. Tracheal anomalies associated with Down syndrome: A systematic review. Pediatric pulmonology. vol 56. issue 5. 2021-10-19. PMID:33434377. |
airway anomalies are accountable for a substantial part of morbidity and mortality in children with down syndrome (ds). |
2021-10-19 |
2023-08-13 |
Not clear |
| Madalina-Petronela Schmidt, Anca Colita, Anca-Viorica Ivanov, Daniel Coriu, Ingrith-Crenguta Miro. Outcomes of patients with Down syndrome and acute leukemia: A retrospective observational study. Medicine. vol 100. issue 40. 2021-10-19. PMID:34622870. |
children with down syndrome (ds) have a higher risk of developing acute leukemia than do those without ds. |
2021-10-19 |
2023-08-13 |
Not clear |
| Marcelo Pino, Fernando Muñoz, Matías Henríquez, Cristian Luarte-Rocha, Rossana Gomez-Campos, Marco Cossio-Bolaños, Luís-Felipe Castelli-de-Campo. [Body adiposity and abdominal muscle resistance in young people with Down syndrome]. Andes pediatrica : revista Chilena de pediatria. vol 92. issue 4. 2021-10-18. PMID:34652372. |
to verify the relationship between abdominal muscle endurance and the level of body fat, measured through the waist-to-height ratio, in young people with down syndrome (ds). |
2021-10-18 |
2023-08-13 |
Not clear |
| Andrew J Aschenbrenner, R Asaad Baksh, Bessy Benejam, Jessica A Beresford-Webb, Antonia Coppus, Juan Fortea, Benjamin L Handen, Sigan Hartley, Elizabeth Head, Judith Jaeger, Johannes Levin, Sandra V Loosli, Anne-Sophie Rebillat, Silvia Sacco, Frederick A Schmitt, Kate E Thurlow, Shahid Zaman, Jason Hassenstab, Andre Strydo. Markers of early changes in cognition across cohorts of adults with Down syndrome at risk of Alzheimer's disease. Alzheimer's & dementia (Amsterdam, Netherlands). vol 13. issue 1. 2021-10-16. PMID:33969175. |
down syndrome (ds), a genetic variant of early onset alzheimer's disease (ad), lacks a suitable outcome measure for prevention trials targeting pre-dementia stages. |
2021-10-16 |
2023-08-13 |
Not clear |