| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Takagi, A Yoshida, K Kinoshita, D Iwashima, S Imamaura, H Iwasaki, H Tsutani, T Ued. Unrelated donor bone marrow transplantation for acute mixed lineage (myeloid and B-lymphoid lineage) leukemia in an adult with Down syndrome. Annals of hematology. vol 82. issue 4. 2003-07-07. PMID:12707727. |
this article describes a rare case of bone marrow transplantation (bmt) from an unrelated donor (urd) in an adult japanese male with down syndrome (ds) diagnosed as having acute mixed lineage leukemia. |
2003-07-07 |
2023-08-12 |
Not clear |
| Peter Bozner, G Lee Wilson, Nadya M Druzhyna, Tara K Bryant-Thomas, Susan P LeDoux, Glenn L Wilson, Miguel A Pappoll. Deficiency of chaperonin 60 in Down's syndrome. Journal of Alzheimer's disease : JAD. vol 4. issue 6. 2003-07-03. PMID:12515899. |
patients with down syndrome (ds) and alzheimer's disease (ad) share a number of characteristic neuropathologic lesions. |
2003-07-03 |
2023-08-12 |
Not clear |
| Pankaj D Mehta, Sangita P Mehta, Betty Fedor, Bruce A Patrick, Mark Emmerling, Arthur J Dalto. Plasma amyloid beta protein 1-42 levels are increased in old Down Syndrome but not in young Down Syndrome. Neuroscience letters. vol 342. issue 3. 2003-07-02. PMID:12757888. |
plasma amyloid beta protein 1-40 (abeta40) and abeta42 levels were quantitated from 28 young down syndrome (ds) (20-40 years old), 28 age-matched controls, 32 old ds (41-65 years old) and 32 age-matched controls in a sandwich enzyme-linked immunosorbent assay. |
2003-07-02 |
2023-08-12 |
Not clear |
| Virginia Volterra, M Cristina Caselli, Olga Capirci, Francesca Tonucci, Stefano Vicar. Early linguistic abilities of Italian children with Williams syndrome. Developmental neuropsychology. vol 23. issue 1-2. 2003-07-01. PMID:12730019. |
previous studies of linguistic and memory abilities in italian-speaking children with williams syndrome (ws) and down syndrome (ds)are briefly reviewed. |
2003-07-01 |
2023-08-12 |
Not clear |
| Ma Francisca Sánchez-Font, Anna Bosch-Comas, Roser Gonzàlez-Duarte, Gemma Marfan. Overexpression of FABP7 in Down syndrome fetal brains is associated with PKNOX1 gene-dosage imbalance. Nucleic acids research. vol 31. issue 11. 2003-06-30. PMID:12771203. |
suppression subtractive hybridization performed on down syndrome (ds) fetal brains revealed a differentially expressed gene, fabp7, mapped to 6q22-23. |
2003-06-30 |
2023-08-12 |
mouse |
| P Venugopalan, A K Agarwa. Spectrum of congenital heart defects associated with Down Syndrome in high consanguineous Omani population. Indian pediatrics. vol 40. issue 5. 2003-06-23. PMID:12768040. |
to identify the pattern of congenital heart defects (chd) in children with down syndrome (ds) in an omani population, and compare it with chd in children without ds and with historical cohorts from populations with low prevalence of consanguinity. |
2003-06-23 |
2023-08-12 |
Not clear |
| b' Rub\\xc3\\xa9n L\\xc3\\xb3pez-P\\xc3\\xa9rez, S A\\xc3\\xadda Borges-Y\\xc3\\xa1\\xc3\\xb1ez, Gustavo Jim\\xc3\\xa9nez-Garc\\xc3\\xada, Gerardo Maupom\\xc3\\xa. Oral hygiene, gingivitis, and periodontitis in persons with Down syndrome. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry. vol 22. issue 6. 2003-06-18. PMID:12790229.' |
using a case-control study design, the authors examined 32 individuals with down syndrome (ds) and matched each with a participant from the control group (cg) according to age and gender. |
2003-06-18 |
2023-08-12 |
human |
| Timothy N Welsh, Digby Elliott, Dominic A Simo. Cerebral specialization and verbal-motor integration in adults with and without Down syndrome. Brain and language. vol 84. issue 2. 2003-06-17. PMID:12590909. |
persons with down syndrome (ds) tend to exhibit an atypical left ear-right hemisphere advantage (lea) for the perception of speech sounds. |
2003-06-17 |
2023-08-12 |
Not clear |
| Guido D'Angelo, Patrizia Merl. Transient myeloproliferative syndrome/transient acute myeloid leukemia in a newborn with Down syndrome: a case report and literature review. Laboratory hematology : official publication of the International Society for Laboratory Hematology. vol 9. issue 1. 2003-06-17. PMID:12661826. |
we report the case of a newborn with down syndrome (ds) associated with transient acute myeloid leukemia (aml). |
2003-06-17 |
2023-08-12 |
Not clear |
| Kurt Krapfenbauer, Ephrem Engidawork, Nigel Cairns, Michael Fountoulakis, Gert Lube. Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders. Brain research. vol 967. issue 1-2. 2003-06-05. PMID:12650976. |
an increasing body of evidence indicates that oxidative stress and damage play a role in the pathogenesis of a number of diseases associated with neurodegeneration, including down syndrome (ds), alzheimer's disease (ad) and pick's disease (pd). |
2003-06-05 |
2023-08-12 |
Not clear |
| Janice H Brown, Mark H Johnson, Sarah J Paterson, Rick Gilmore, Elena Longhi, Annette Karmiloff-Smit. Spatial representation and attention in toddlers with Williams syndrome and Down syndrome. Neuropsychologia. vol 41. issue 8. 2003-06-04. PMID:12667539. |
the nature of the spatial representations that underlie simple visually guided actions early in life was investigated in toddlers with williams syndrome (ws), down syndrome (ds), and healthy chronological age- and mental age-matched controls, through the use of a "double-step" saccade paradigm. |
2003-06-04 |
2023-08-12 |
Not clear |
| Kenneth I Lim, Denise Pugash, Jerome Dansereau, R Douglas Wilso. Nuchal index: a gestational age independent ultrasound marker for the detection of Down syndrome. Prenatal diagnosis. vol 22. issue 13. 2003-06-03. PMID:12478640. |
to determine if the ultrasound marker nuchal index (nix) is gestational age independent, and to determine its specificity and sensitivity for down syndrome (ds) identification. |
2003-06-03 |
2023-08-12 |
Not clear |
| Bruce F Pennington, Jennifer Moon, Jamie Edgin, Jennifer Stedron, Lynn Nade. The neuropsychology of Down syndrome: evidence for hippocampal dysfunction. Child development. vol 74. issue 1. 2003-05-28. PMID:12625437. |
this study tested prefrontal and hippocampal functions in a sample of 28 school-aged (m = 14.7 years, sd = 2.7) individuals with down syndrome (ds) compared with 28 (m = 4.9 years, sd = .75) typically developing children individually matched on mental age (ma). |
2003-05-28 |
2023-08-12 |
mouse |
| P P Thirunavukarasu, G Lambert-Messerlian, D M Robertson, G Dawson, J Canick, E M Wallac. Molecular weight forms of inhibin A, inhibin B and pro-alphaC in maternal serum, amniotic fluid and placental extracts of normal and Down syndrome pregnancies. Prenatal diagnosis. vol 22. issue 12. 2003-05-20. PMID:12454963. |
inhibin a, an established prenatal marker of down syndrome (ds), exists in the maternal circulation in a number of isoforms. |
2003-05-20 |
2023-08-12 |
Not clear |
| Cristina Targa Ferreira, Júlio César Leite, Adriano Nori R Tanaguchi, Sandra Maria G Vieira, Jorge Pereira-Lima, Themis Reverbel da Silveir. Seroprevalence of hepatitis a antibodies in a group of normal and Down syndrome children in Porto Alegre, southern Brazil. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. vol 6. issue 5. 2003-05-15. PMID:12495604. |
the high incidence of hepatitis a and b in institutionalized patients with down syndrome (ds) is not fully understood. |
2003-05-15 |
2023-08-12 |
Not clear |
| James H Heller, Gail A Spiridigliozzi, Jennifer A Sullivan, P Murali Doraiswamy, Ranga R Krishnan, Priya S Kishnan. Donepezil for the treatment of language deficits in adults with Down syndrome: a preliminary 24-week open trial. American journal of medical genetics. Part A. vol 116A. issue 2. 2003-05-09. PMID:12494428. |
at present, there is no proven pharmacologic treatment for cognitive or language impairments in down syndrome (ds). |
2003-05-09 |
2023-08-12 |
Not clear |
| A S P van Trotsenburg, T Vulsma, H M van Santen, W Cheung, J J M de Vijlde. Lower neonatal screening thyroxine concentrations in down syndrome newborns. The Journal of clinical endocrinology and metabolism. vol 88. issue 4. 2003-05-09. PMID:12679431. |
there is an unexplained higher incidence of congenital hypothyroidism (ch) detected by t(4)-based neonatal screening programs and a very high prevalence of (mild) plasma tsh elevation in young children with down syndrome (ds). |
2003-05-09 |
2023-08-12 |
Not clear |
| G Hedov, K Wikblad, G Anneré. First information and support provided to parents of children with Down syndrome in Sweden: clinical goals and parental experiences. Acta paediatrica (Oslo, Norway : 1992). vol 91. issue 12. 2003-05-06. PMID:12578293. |
when parents are informed that their newborn child has down syndrome (ds), they often respond with a traumatic crisis reaction. |
2003-05-06 |
2023-08-12 |
Not clear |
| Heather A Bimonte-Nelson, Christopher L Hunter, Matthew E Nelson, Ann-Charlotte E Granhol. Frontal cortex BDNF levels correlate with working memory in an animal model of Down syndrome. Behavioural brain research. vol 139. issue 1-2. 2003-05-02. PMID:12642175. |
individuals with down syndrome (ds) develop most neuropathological hallmarks of alzheimer's disease early in life, including loss of cholinergic markers in the basal forebrain. |
2003-05-02 |
2023-08-12 |
mouse |
| Laura Brunelli das Neves Grillo, Gregório Lorenzo Acácio, Ricardo Barini, Walter Pinto, Carmen Silvia Bertuzz. [Mutations in the methylene-tetrahydrofolate reductase gene and Down syndrome]. Cadernos de saude publica. vol 18. issue 6. 2003-05-01. PMID:12488908. |
down syndrome (ds) is a complex genetic and metabolic disorder attributed to the presence of three copies of chromosome 21. |
2003-05-01 |
2023-08-12 |
Not clear |