| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kyogo Suzuki, Hideki Muramatsu, Yusuke Okuno, Atsushi Narita, Asahito Hama, Yoshiyuki Takahashi, Makoto Yoshida, Yasuo Horikoshi, Ken-Ichiro Watanabe, Kazuko Kudo, Seiji Kojim. Immunosuppressive therapy for patients with Down syndrome and idiopathic aplastic anemia. International journal of hematology. vol 104. issue 1. 2017-03-13. PMID:27107757. |
idiopathic aplastic anemia (aa) is a rare hematological complication of down syndrome (ds). |
2017-03-13 |
2023-08-13 |
human |
| Jordana Costa Soares, Juliana Granja Urosas, Karenina Santos Calarga, Tathiany Silva Pichelli, Suelly Cecília Olivan Limongi, Navid Shahnaz, Renata Mota Mamede Carvall. Wideband reflectance in Down syndrome. International journal of pediatric otorhinolaryngology. vol 87. 2017-03-13. PMID:27368466. |
children with down syndrome (ds) have a high incidence of middle ear disorders and congenital abnormalities of the external, middle and inner ear. |
2017-03-13 |
2023-08-13 |
Not clear |
| E R Villani, G Onder, A Carfì, C Di Segni, S Raimondo, A Silvestrini, E Meucci, A Mancin. Thyroid Function and its Implications in Oxidative Stress Influencing the Pathogenesis of Osteoporosis in Adults with Down Syndrome: A Cohort Study. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 48. issue 9. 2017-03-13. PMID:27557341. |
people with down syndrome (ds) show lower bone mass density (bmd) and a higher prevalence of hypothyroidism compared to general population. |
2017-03-13 |
2023-08-13 |
Not clear |
| Lei Wang, Zhifei Li, Xiaobo Song, Li Liu, Guohai Su, Ying Cu. Bioinformatic Analysis of Genes and MicroRNAs Associated With Atrioventricular Septal Defect in Down Syndrome Patients. International heart journal. vol 57. issue 4. 2017-03-07. PMID:27396555. |
down syndrome (ds) is a common chromosome 21 abnormality disease, leading to various health problems, especially atrioventricular septal defect (avsd). |
2017-03-07 |
2023-08-13 |
Not clear |
| b' Fabio Copped\\xc3\\xa. Risk factors for Down syndrome. Archives of toxicology. vol 90. issue 12. 2017-03-03. PMID:27600794.' |
down syndrome (ds) originates, in most of the cases (95 %), from a full trisomy of chromosome 21. |
2017-03-03 |
2023-08-13 |
Not clear |
| Sanaa Benhaourech, Abdenasser Drighil, Ayoub El Hammir. Congenital heart disease and Down syndrome: various aspects of a confirmed association. Cardiovascular journal of Africa. vol 27. issue 5. 2017-02-27. PMID:27805241. |
congenital heart disease (chd) is frequently described in patients with down syndrome (ds) and is the main cause of death in this population during the first two years of life. |
2017-02-27 |
2023-08-13 |
Not clear |
| Liqun Yin, Mark A Lovell, Michael L Wilson, Qi Wei, Xiayuan Lian. Distinct GATA1 Point Mutations in Monozygotic Twins With Down Syndrome and Transient Abnormal Myelopoiesis From a Triplet Pregnancy: A Case Report and Review of Literature. American journal of clinical pathology. vol 146. issue 6. 2017-02-27. PMID:28028114. |
down syndrome (ds)-associated transient abnormal myelopoiesis (tam) or acute megakaryoblastic leukemia (amkl) in monozygotic twins is exceedingly rare and has not been well characterized. |
2017-02-27 |
2023-08-13 |
Not clear |
| Emmanuel Spaggiari, Isabelle Czerkiewicz, Corinne Sault, Sophie Dreux, Armelle Galland, Laurent J Salomon, Yves Ville, Françoise Mulle. Impact of Including or Removing Nuchal Translucency Measurement on the Detection and False-Positive Rates of First-Trimester Down Syndrome Screening. Fetal diagnosis and therapy. vol 40. issue 3. 2017-02-24. PMID:26656919. |
first-trimester down syndrome (ds) screening combining maternal age, serum markers (pregnancy-associated plasma protein-a and beta-human chorionic gonadotropin) and nuchal translucency (nt) gives an 85% detection rate for a 5% false-positive rate. |
2017-02-24 |
2023-08-13 |
Not clear |
| Caterina Manna, Arbace Officioso, Francesca Trojsi, Gioacchino Tedeschi, Silvia Leoncini, Cinzia Signorini, Lucia Ciccoli, Claudio De Felic. Increased non-protein bound iron in Down syndrome: contribution to lipid peroxidation and cognitive decline. Free radical research. vol 50. issue 12. 2017-02-24. PMID:27785947. |
down syndrome (ds, trisomy 21) is the leading cause of chromosomal-related intellectual disability. |
2017-02-24 |
2023-08-13 |
Not clear |
| Olga Sánchez, Carmen Domínguez, Aina Ruiz, Irene Ribera, Jaume Alijotas, Lluís Cabero, Elena Carreras, Elisa Llurb. Angiogenic Gene Expression in Down Syndrome Fetal Hearts. Fetal diagnosis and therapy. vol 40. issue 1. 2017-02-23. PMID:26513650. |
forty percent of down syndrome (ds) fetuses have congenital heart defects (chd). |
2017-02-23 |
2023-08-13 |
Not clear |
| Elizabeth Martínez, Diana Castañeda, Sonia Jaramillo, Alejandro Iregui, Tatiana Quiñonez, Jairo A Rodríguez, Eddy Herrera, Ana Milena Gómez, Martin A Rondón, Juan Carlos Prieto, Juana Angel, Manuel A Franco, Martha C Mes. Altered immune parameters correlate with infection-related hospitalizations in children with Down syndrome. Human immunology. vol 77. issue 7. 2017-02-17. PMID:27166175. |
in addition to previously studied immunological variables, the relative expression of ifngr2, ifnar1, cd18, and cd275 (all encoded in chromosome 21) on circulating leucocytes and multifunctional t cells (evaluated by an intracellular cytokine/proliferation assay) were compared between children with down syndrome (ds) and healthy controls (hc). |
2017-02-17 |
2023-08-13 |
Not clear |
| Alberto Lerario, Irene Colombo, Donatella Milani, Lorenzo Peverelli, Luisa Villa, Roberto Del Bo, Monica Sciacco, Giacomo Pietro Comi, Susanna Esposito, Maurizio Moggi. A case report with the peculiar concomitance of 2 different genetic syndromes. Medicine. vol 95. issue 49. 2017-02-15. PMID:27930565. |
down syndrome (ds) is the most common chromosome disorder in live born infants, affecting several body systems, but usually sparing skeletal muscles. |
2017-02-15 |
2023-08-13 |
Not clear |
| Lucy Wilde, Anna Mitchell, Chris Olive. Differences in Social Motivation in Children with Smith-Magenis Syndrome and Down Syndrome. Journal of autism and developmental disorders. vol 46. issue 6. 2017-02-14. PMID:26983920. |
in down syndrome (ds) strong social motivation is described, but less commonly associated with behavioural problems. |
2017-02-14 |
2023-08-13 |
Not clear |
| Ashokan Arumugam, Kavitha Raja, Mahalakshmi Venugopalan, Baskaran Chandrasekaran, Kesava Kovanur Sampath, Hariraja Muthusamy, Nagarani Shanmuga. Down syndrome-A narrative review with a focus on anatomical features. Clinical anatomy (New York, N.Y.). vol 29. issue 5. 2017-02-06. PMID:26599319. |
down syndrome (ds) is the most common aneuploidy of chromosome 21, characterized by the presence of an extra copy of that chromosome (trisomy 21). |
2017-02-06 |
2023-08-13 |
Not clear |
| Ni-Chung Lee, Yin-Hsiu Chien, Wuh-Liang Hw. Integrated care for Down syndrome. Congenital anomalies. vol 56. issue 3. 2017-02-06. PMID:26866291. |
down syndrome (ds), caused by an extra copy of chromosome 21 (trisomy 21), is the most intensively studied human aneuploidy condition. |
2017-02-06 |
2023-08-13 |
human |
| Y Q Chen, T Li, W Y Guo, F J Su, Y X Zhan. Identification of altered pathways in Down syndrome-associated congenital heart defects using an individualized pathway aberrance score. Genetics and molecular research : GMR. vol 15. issue 2. 2017-02-06. PMID:27173257. |
the aim of this study was to identify disrupted pathways related to down syndrome (ds), and ds-associated congenital heart defects (ds-chd). |
2017-02-06 |
2023-08-13 |
human |
| Paola Sabrina Buonuomo, Andrea Bartuli, Gerarda Mastrogiorgio, Annachiara Vittucci, Chiara Di Camillo, Simona Bianchi, Denise Pires Marafon, Alberto Villani, Diletta Valentin. Lipid profiles in a large cohort of Italian children with Down syndrome. European journal of medical genetics. vol 59. issue 8. 2017-02-06. PMID:27343989. |
results of epidemiological studies of lipid profiles in individuals with down syndrome (ds) in different settings showed discordant results but laboratory norms for this population has been lacking. |
2017-02-06 |
2023-08-13 |
Not clear |
| Wei-Li Shi, Zhong-Zhen Liu, Hong-Dan Wang, Dong Wu, Hui Zhang, Hai Xiao, Yan Chu, Qiao-Fang Hou, Shi-Xiu Lia. Integrated miRNA and mRNA expression profiling in fetal hippocampus with Down syndrome. Journal of biomedical science. vol 23. issue 1. 2017-02-01. PMID:27266699. |
down syndrome (ds), caused by triplication of human chromosome 21, is the most common aneuploidies. |
2017-02-01 |
2023-08-13 |
human |
| E Sacide Çağlaya. Generation of improved human cerebral organoids from single copy DYRK1A knockout induced pluripotent stem cells in trisomy 21: hypothetical solutions for neurodevelopmental models and therapeutic alternatives in down syndrome. Cell biology international. vol 40. issue 12. 2017-01-31. PMID:27743462. |
dual-specificity thyrosine phosphorylation-regulated kinase 1a (dyrk1a) is a strong therapeutic target to ameliorate cognitive functions of down syndrome (ds). |
2017-01-31 |
2023-08-13 |
mouse |
| Masashi Asai, Aimi Kinjo, Shoko Kimura, Ryotaro Mori, Takashi Kawakubo, Keiro Shirotani, Sosuke Yagishita, Kei Maruyama, Nobuhisa Iwat. Perturbed Calcineurin-NFAT Signaling Is Associated with the Development of Alzheimer's Disease. Biological & pharmaceutical bulletin. vol 39. issue 10. 2017-01-27. PMID:27725441. |
down syndrome (ds), the most common genetic disorder, is caused by trisomy 21. |
2017-01-27 |
2023-08-13 |
Not clear |