| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eun Kyoung Choi, Il Young Yo. Resilience in families of children with Down syndrome in Korea. International journal of nursing practice. vol 21. issue 5. 2017-01-24. PMID:24750308. |
this study aims to identify the factors related to resilience of the families of children with down syndrome (ds). |
2017-01-24 |
2023-08-13 |
Not clear |
| Antonella Tramutola, Gilda Pupo, Fabio Di Domenico, Eugenio Barone, Andrea Arena, Chiara Lanzillotta, Diede Brokeaart, Carla Blarzino, Elizabeth Head, D Allan Butterfield, Marzia Perluig. Activation of p53 in Down Syndrome and in the Ts65Dn Mouse Brain is Associated with a Pro-Apoptotic Phenotype. Journal of Alzheimer's disease : JAD. vol 52. issue 1. 2017-01-23. PMID:26967221. |
down syndrome (ds) is the most common genetic cause of intellectual disability, resulting from trisomy of chromosome 21. |
2017-01-23 |
2023-08-13 |
mouse |
| Nanda C de Knegt, Carlo Schuengel, Heleen M Evenhuis, Frank Lobbezoo, Erik J A Scherde. Apolipoprotein E ɛ4, Cognitive Function, and Pain Experience in Down Syndrome: A Pilot Study. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists. vol 31. issue 5. 2017-01-20. PMID:27193365. |
this hypothesis is clinically relevant to examine in adults with down syndrome (ds) because they are at risk for painful physical conditions, their presence of apoe ε4 is related to cognitive impairment, and their pain experience is unclear. |
2017-01-20 |
2023-08-13 |
Not clear |
| Lourdes Gutiérrez-Vilahú, Núria Massó-Ortigosa, Lluís Costa-Tutusaus, Miriam Guerra-Balic, Ferran Rey-Abell. Comparison of Static Balance on a Platform in Young Adults With Down Syndrome Before and After a Dance Program. Adapted physical activity quarterly : APAQ. vol 33. issue 3. 2017-01-20. PMID:27623608. |
the purpose of the study was to compare postural control in static standing in young adults with and without down syndrome (ds), with eyes closed and eyes open, before and after an 18-wk dance-based training program. |
2017-01-20 |
2023-08-13 |
human |
| Adam Love, Stamatis Agiovlasiti. How Do Adults With Down Syndrome Perceive Physical Activity? Adapted physical activity quarterly : APAQ. vol 33. issue 3. 2017-01-20. PMID:27623609. |
adults with down syndrome (ds) tend to have low physical activity levels, which may relate to how they perceive participation in physical activities. |
2017-01-20 |
2023-08-13 |
Not clear |
| Andrea Romano, Riccardo Cornia, Marta Moraschi, Alessandro Bozzao, Laura Chiacchiararelli, Valeria Coppola, Cristina Iani, Giacomo Stella, Giorgio Albertini, Alberto Pierallin. Age-Related Cortical Thickness Reduction in Non-Demented Down's Syndrome Subjects. Journal of neuroimaging : official journal of the American Society of Neuroimaging. vol 26. issue 1. 2017-01-18. PMID:25996840. |
the aim of this study was to investigate the characteristic pattern of age-related cortical thinning in patients with down syndrome (ds), as assessed by mri and automatic cortical thickness measurements. |
2017-01-18 |
2023-08-13 |
human |
| Meng-Ju Li, Ni-Chung Lee, Yung-Li Yang, Hsiu-Ju Yen, Hsiu-Hao Chang, Yin-Hsiu Chien, Meng-Yao Lu, Shiann-Tarng Jou, Kai-Hsin Lin, Wuh-Liang Hwu, Dong-Tsamn Li. Long-term outcome for Down syndrome patients with hematopoietic disorders. Journal of the Formosan Medical Association = Taiwan yi zhi. vol 115. issue 2. 2017-01-17. PMID:26234152. |
although down syndrome (ds) patients have a higher risk of developing transient myeloproliferative disorder (tmd) and acute leukemia, very little data is available on long-term outcome in taiwanese patients. |
2017-01-17 |
2023-08-13 |
Not clear |
| Maurício José Santos Moreira, Carolina Schwertner, Débora Grando, Lavinia Schuler Faccini, Lina Naomi Hashizum. Oral Health Status and Salivary Levels of Mutans Streptococci in Children with Down Syndrome. Pediatric dentistry. vol 37. issue 4. 2017-01-17. PMID:26314603. |
the literature on the oral health status of down syndrome (ds) patients is controversial. |
2017-01-17 |
2023-08-13 |
Not clear |
| Cláudia Regina Santos Silva, Joice Matos Biselli-Périco, Bruna Lancia Zampieri, Wilson Araujo Silva, Jorge Estefano Santana de Souza, Matheus Carvalho Bürger, Eny Maria Goloni-Bertollo, Érika Cristina Pavarin. Differential Expression of Inflammation-Related Genes in Children with Down Syndrome. Mediators of inflammation. vol 2016. 2017-01-17. PMID:27293319. |
the aim of the study was to investigate the expression patterns of a specific set of genes involved in the inflammation process in children with down syndrome (ds) and children without the syndrome (control group) to identify differences that may be related to the immune abnormalities observed in ds individuals. |
2017-01-17 |
2023-08-13 |
Not clear |
| Teresa N Sparks, Emily Griffin, Jessica Page, Rachel Pilliod, Brian L Shaffer, Aaron B Caughe. Down syndrome: perinatal mortality risks with each additional week of expectant management. Prenatal diagnosis. vol 36. issue 4. 2017-01-13. PMID:26891366. |
to evaluate the gestational age (ga) at which perinatal mortality risk is minimized for fetuses with down syndrome (ds). |
2017-01-13 |
2023-08-13 |
Not clear |
| Satoshi Said. Evolution of myeloid leukemia in children with Down syndrome. International journal of hematology. vol 103. issue 4. 2017-01-11. PMID:26910243. |
children with down syndrome (ds) have a markedly increased risk of leukemia. |
2017-01-11 |
2023-08-13 |
Not clear |
| S Kim, Y Sato, P S Mohan, C Peterhoff, A Pensalfini, A Rigoglioso, Y Jiang, R A Nixo. Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer's disease. Molecular psychiatry. vol 21. issue 5. 2017-01-10. PMID:26194181. |
here, we show that the rab5 effector appl1 (adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif) mediates rab5 overactivation in down syndrome (ds) and ad, which is caused by elevated levels of the β-cleaved carboxy-terminal fragment of app (βctf). |
2017-01-10 |
2023-08-13 |
Not clear |
| Shani Stern, Menahem Segal, Elisha Mose. Involvement of Potassium and Cation Channels in Hippocampal Abnormalities of Embryonic Ts65Dn and Tc1 Trisomic Mice. EBioMedicine. vol 2. issue 9. 2017-01-10. PMID:26501103. |
down syndrome (ds) mouse models exhibit cognitive deficits, and are used for studying the neuronal basis of ds pathology. |
2017-01-10 |
2023-08-13 |
mouse |
| Eva Lana-Elola, Sheona Watson-Scales, Amy Slender, Dorota Gibbins, Alexandrine Martineau, Charlotte Douglas, Timothy Mohun, Elizabeth Mc Fisher, Victor Lj Tybulewic. Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel. eLife. vol 5. 2017-01-10. PMID:26765563. |
down syndrome (ds), caused by trisomy of human chromosome 21 (hsa21), is the most common cause of congenital heart defects (chd), yet the genetic and mechanistic causes of these defects remain unknown. |
2017-01-10 |
2023-08-13 |
mouse |
| Lesley Doyle, Kathryn J Saunders, Julie-Anne Littl. Trying to see, failing to focus: near visual impairment in Down syndrome. Scientific reports. vol 6. 2017-01-10. PMID:26847360. |
the majority of individuals with down syndrome (ds) do not exhibit accurate accommodation, with the aetiology of this deficit unknown. |
2017-01-10 |
2023-08-13 |
human |
| Dean D'Souza, Rhonda Booth, Monica Connolly, Francesca Happé, Annette Karmiloff-Smit. Rethinking the concepts of 'local or global processors': evidence from Williams syndrome, Down syndrome, and Autism Spectrum Disorders. Developmental science. vol 19. issue 3. 2017-01-03. PMID:26010432. |
both williams syndrome (ws) and autism spectrum disorder (asd) have been characterized as preferentially processing local information, whereas in down syndrome (ds) the reported tendency is to process stimuli globally. |
2017-01-03 |
2023-08-13 |
human |
| Patrick J Lao, Tobey J Betthauser, Ansel T Hillmer, Julie C Price, William E Klunk, Iulia Mihaila, Andrew T Higgins, Peter D Bulova, Sigan L Hartley, Regina Hardison, Rameshwari V Tumuluru, Dhanabalan Murali, Chester A Mathis, Annie D Cohen, Todd E Barnhart, Darlynne A Devenny, Marsha R Mailick, Sterling C Johnson, Benjamin L Handen, Bradley T Christia. The effects of normal aging on amyloid-β deposition in nondemented adults with Down syndrome as imaged by carbon 11-labeled Pittsburgh compound B. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 12. issue 4. 2017-01-03. PMID:26079411. |
in down syndrome (ds), the overproduction of amyloid precursor protein is hypothesized to predispose young adults to early expression of alzheimer-like neuropathology. |
2017-01-03 |
2023-08-13 |
Not clear |
| Yili Wu, Si Zhang, Qin Xu, Haiyan Zou, Weihui Zhou, Fang Cai, Tingyu Li, Weihong Son. Regulation of global gene expression and cell proliferation by APP. Scientific reports. vol 6. 2017-01-03. PMID:26936520. |
down syndrome (ds), caused by trisomy of chromosome 21, is one of the most common genetic disorders. |
2017-01-03 |
2023-08-13 |
human |
| Irushi Abeysekera, Jared Thomas, Taxiarchis M Georgiadis, Alycia G Berman, Max A Hammond, Karl J Dria, Joseph M Wallace, Randall J Rope. Differential effects of Epigallocatechin-3-gallate containing supplements on correcting skeletal defects in a Down syndrome mouse model. Molecular nutrition & food research. vol 60. issue 4. 2016-12-30. PMID:26748562. |
down syndrome (ds), caused by trisomy of human chromosome 21 (hsa21), is characterized by a spectrum of phenotypes including skeletal abnormalities. |
2016-12-30 |
2023-08-13 |
mouse |
| Jessica H Hall, Frances K Wiseman, Elizabeth M C Fisher, Victor L J Tybulewicz, John L Harwood, Mark A Goo. Tc1 mouse model of trisomy-21 dissociates properties of short- and long-term recognition memory. Neurobiology of learning and memory. vol 130. 2016-12-30. PMID:26868479. |
the present study examined memory function in tc1 mice, a transchromosomic model of down syndrome (ds). |
2016-12-30 |
2023-08-13 |
mouse |