| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tao Jiang, Jie Ding, Xiao-Qing Zhang, Xiao-Juan Zhang, Bin Zhang, Ting Wang, Bin Y. Analysis of Down syndrome failed to be diagnosed after prenatal screening: A multicenter study. Medicine. vol 96. issue 24. 2017-07-06. PMID:28614251. |
to analyze the characters of down syndrome (ds) who failed to be diagnosed after prenatal screening and hope to be able to improve the programs of prenatal screening and reduce the missed diagnosis of ds. |
2017-07-06 |
2023-08-13 |
human |
| Hellen Medeiros Kazan, Alessandra Giannella Samelli, Ivone Ferreira Neves-Lobo, Fernanda Cristina Leite Magliaro, Suelly Cecília Olivan Limongi, Carla Gentile Mata. Electrophysiological characterization of hearing in individuals with Down syndrome. CoDAS. vol 28. issue 6. 2017-07-05. PMID:27982254. |
few studies have performed brainstem (baep) and p300 auditory evoked potentials simultaneously to assess central auditory pathways in normal hearing individuals with down syndrome (ds), mainly because of the difficulty in applying these procedures to this population. |
2017-07-05 |
2023-08-13 |
Not clear |
| M Arvio, L Luostarine. Down syndrome in adults: a 27-year follow-up of adaptive skills. Clinical genetics. vol 90. issue 5. 2017-06-30. PMID:27067497. |
in 1988, we assessed the adaptive skills of 45 adults with down syndrome (ds) (21 women and 24 men, age 20-58) with the portage scale. |
2017-06-30 |
2023-08-13 |
human |
| Ramón Pérez-Núñez, Natalia Barraza, Arlek Gonzalez-Jamett, Ana Maria Cárdenas, Jean-Vianney Barnier, Pablo Caviede. Overexpressed Down Syndrome Cell Adhesion Molecule (DSCAM) Deregulates P21-Activated Kinase (PAK) Activity in an In Vitro Neuronal Model of Down Syndrome: Consequences on Cell Process Formation and Extension. Neurotoxicity research. vol 30. issue 1. 2017-06-26. PMID:26966010. |
in humans, down syndrome (ds) is caused by the presence of an extra copy of autosome 21. |
2017-06-26 |
2023-08-13 |
mouse |
| Jason D Marsack, Ayeswarya Ravikumar, Julia S Benoit, Heather A Anderso. Variability in Objective Refraction for Persons with Down Syndrome. Optometry and vision science : official publication of the American Academy of Optometry. vol 94. issue 5. 2017-06-26. PMID:28288016. |
down syndrome (ds) is associated with ocular and cognitive sequelae, which both have the potential to influence clinical measures of refractive error. |
2017-06-26 |
2023-08-13 |
human |
| Jacquelyn A Hatch-Stein, Babette S Zemel, Divya Prasad, Heidi J Kalkwarf, Mary Pipan, Sheela N Magge, Andrea Kell. Body Composition and BMI Growth Charts in Children With Down Syndrome. Pediatrics. vol 138. issue 4. 2017-06-22. PMID:27630073. |
new us down syndrome (ds) bmi growth charts were recently published, but their utility in identifying children with excess adiposity or increased cardiometabolic risk (cmr) remains unknown. |
2017-06-22 |
2023-08-13 |
Not clear |
| Hitoshi Kawada, Atsushi Inanobe, Yoshihisa Kurach. Isolation of proflavine as a blocker of G protein-gated inward rectifier potassium channels by a cell growth-based screening system. Neuropharmacology. vol 109. 2017-06-19. PMID:27236080. |
the overexpression of kir3.2, a subunit of the g protein-gated inwardly rectifying k(+) channel, is implicated in some of the neurological phenotypes of down syndrome (ds). |
2017-06-19 |
2023-08-13 |
xenopus_laevis |
| Francesco Ceppi, Derek Stephens, Barbara S den Hollander, Joerg Krueger, James Whitlock, Lillian Sung, Johann Hitzle. Clinical presentation and risk factors of serious infections in children with Down syndrome treated for acute lymphoblastic leukemia. Pediatric blood & cancer. vol 63. issue 11. 2017-06-16. PMID:27399585. |
treatment of acute lymphoblastic leukemia (all) in children with down syndrome (ds) is associated with a higher incidence of life-threatening infections compared to the overall pediatric population. |
2017-06-16 |
2023-08-13 |
Not clear |
| Fabio Bertapelli, Stamatis Agiovlasitis, Maira Rossmann Machado, Raísa do Val Roso, Gil Guerra-Junio. Growth charts for Brazilian children with Down syndrome: Birth to 20 years of age. Journal of epidemiology. vol 27. issue 6. 2017-06-15. PMID:28320584. |
the growth of youth with down syndrome (ds) differs from that of youth without ds, and growth charts specific to ds have been developed. |
2017-06-15 |
2023-08-13 |
Not clear |
| Qian Chen, Bin Tan, Jun-Lin He, Xue-Qing Liu, Xue-Mei Chen, Ru-Fei Gao, Jing Zhu, Ying-Xiong Wang, Hong-Bo Q. Mutational spectrum of CENP-B box and α-satellite DNA on chromosome 21 in Down syndrome children. Molecular medicine reports. vol 15. issue 4. 2017-06-12. PMID:28259924. |
however, the association between the deoxynucleotide alterations of the cenp‑b box and the extra chromosome 21 (chr21) present in patients with down syndrome (ds) remains to be elucidated. |
2017-06-12 |
2023-08-13 |
Not clear |
| L J Kay, T K Smulders-Srinivasan, M Soundararaja. Understanding the Multifaceted Role of Human Down Syndrome Kinase DYRK1A. Advances in protein chemistry and structural biology. vol 105. 2017-06-06. PMID:27567487. |
the dual-specificity tyrosine (y) phosphorylation-regulated kinase dyrk1a, also known as down syndrome (ds) kinase, is a dosage-dependent signaling kinase that was originally shown to be highly expressed in ds patients as a consequence of trisomy 21. |
2017-06-06 |
2023-08-13 |
human |
| Krutika Joshi, Lily Shen, Avner Michaeli, Michael Salter, Gabrielle Thibault-Messier, Sumaiya Hashmi, James H Eubanks, Miguel A Cortez, O Carter Snea. Infantile spasms in down syndrome: Rescue by knockdown of the GIRK2 channel. Annals of neurology. vol 80. issue 4. 2017-06-05. PMID:27462820. |
the ts65dn (ts) mouse model of down syndrome (ds) is exquisitely sensitive to an infantile spasms phenotype induced by γ-aminobutyric acidb receptor (gabab r) agonists. |
2017-06-05 |
2023-08-13 |
mouse |
| Mieke Maris, Stijn Verhulst, Marek Wojciechowski, Paul Van de Heyning, An Boudewyn. Outcome of adenotonsillectomy in children with Down syndrome and obstructive sleep apnoea. Archives of disease in childhood. vol 102. issue 4. 2017-06-05. PMID:27484971. |
to evaluate the outcome of adenotonsillectomy (at) in a cohort of children with down syndrome (ds) and obstructive sleep apnoea (osa). |
2017-06-05 |
2023-08-13 |
Not clear |
| Elizabeth G Salazar, Yimei Li, Brian T Fisher, Susan R Rheingold, Julie Fitzgerald, Alix E Seif, Yuan-Shung Huang, Rochelle Bagatell, Richard Aplen. Supportive care utilization and treatment toxicity in children with Down syndrome and acute lymphoid leukaemia at free-standing paediatric hospitals in the United States. British journal of haematology. vol 174. issue 4. 2017-06-02. PMID:27161549. |
although inferior outcomes of children with down syndrome (ds) and acute lymphoid leukaemia (all) are established, national supportive care patterns for these patients are unknown. |
2017-06-02 |
2023-08-13 |
Not clear |
| Rachel G Sinkey, Anthony O Odib. Cost-Effectiveness of Old and New Technologies for Aneuploidy Screening. Clinics in laboratory medicine. vol 36. issue 2. 2017-05-31. PMID:27235909. |
several studies have examined cost-effectiveness of down syndrome (ds) screening and found it to be cost-effective. |
2017-05-31 |
2023-08-13 |
Not clear |
| Nady El Hajj, Marcus Dittrich, Julia Böck, Theo F J Kraus, Indrajit Nanda, Tobias Müller, Larissa Seidmann, Tim Tralau, Danuta Galetzka, Eberhard Schneider, Thomas Haa. Epigenetic dysregulation in the developing Down syndrome cortex. Epigenetics. vol 11. issue 8. 2017-05-31. PMID:27245352. |
using illumina 450k arrays, 1.85% of all analyzed cpg sites were significantly hypermethylated and 0.31% hypomethylated in fetal down syndrome (ds) cortex throughout the genome. |
2017-05-31 |
2023-08-13 |
Not clear |
| Francine A van den Driessen Mareeuw, Mirjam I Hollegien, Antonia M W Coppus, Diana M J Delnoij, Esther de Vrie. In search of quality indicators for Down syndrome healthcare: a scoping review. BMC health services research. vol 17. issue 1. 2017-05-31. PMID:28420357. |
the medical care chain around down syndrome (ds) is complex, with many multidisciplinary challenges. |
2017-05-31 |
2023-08-13 |
Not clear |
| Qiang Liu, Yu Tang, Long Chen, Na Liu, Fangfang Lang, Heng Liu, Pin Wang, Xiulian Su. E3 Ligase SCFβTrCP-induced DYRK1A Protein Degradation Is Essential for Cell Cycle Progression in HEK293 Cells. The Journal of biological chemistry. vol 291. issue 51. 2017-05-29. PMID:27807027. |
dyrk1a, located on the down syndrome (ds) critical region of chromosome 21, was found to be overexpressed in brains of ds and alzheimer's disease individuals. |
2017-05-29 |
2023-08-13 |
Not clear |
| Antonia Cárdenas, María A Paul, Catalina Correa, Sebastián Valderrama, Jaime Cerda, Macarena Lizam. [Morbidity profile among adolescents with Down syndrome]. Revista medica de Chile. vol 144. issue 8. 2017-05-26. PMID:27905645. |
there is a paucity of information about morbidity and mortality of adolescents with down syndrome (ds). |
2017-05-26 |
2023-08-13 |
Not clear |
| Melinda J Pierce, Stephen H LaFranchi, Joseph D Pinte. Characterization of Thyroid Abnormalities in a Large Cohort of Children with Down Syndrome
. Hormone research in paediatrics. vol 87. issue 3. 2017-05-22. PMID:28259872. |
thyroid disease is a common comorbidity in individuals with down syndrome (ds), but historical studies have multiple limitations. |
2017-05-22 |
2023-08-13 |
Not clear |