| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoyong Pan, Xiaohua Hu, Yu Hang Zhang, Kaiyan Feng, Shao Peng Wang, Lei Chen, Tao Huang, Yu Dong Ca. Identifying Patients with Atrioventricular Septal Defect in Down Syndrome Populations by Using Self-Normalizing Neural Networks and Feature Selection. Genes. vol 9. issue 4. 2019-11-20. PMID:29649131. |
atrioventricular septal defect (avsd) is a clinically significant subtype of congenital heart disease (chd) that severely influences the health of babies during birth and is associated with down syndrome (ds). |
2019-11-20 |
2023-08-13 |
Not clear |
| R M Vaughan, C McGee, S Guerin, J Tyrrell, P Dod. The challenges of diagnosis and treatment of dementia in Down's syndrome. Irish journal of psychological medicine. vol 33. issue 3. 2019-11-20. PMID:30115189. |
people with down syndrome (ds) are at high risk for developing dementia and early diagnosis is vital in enhancing quality of life. |
2019-11-20 |
2023-08-13 |
Not clear |
| Antonella Tramutola, Chiara Lanzillotta, Eugenio Barone, Andrea Arena, Ilaria Zuliani, Luciana Mosca, Carla Blarzino, D Allan Butterfield, Marzia Perluigi, Fabio Di Domenic. Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome. Translational neurodegeneration. vol 7. 2019-11-20. PMID:30410750. |
down syndrome (ds) individuals, by the age of 40s, are at increased risk to develop alzheimer-like dementia, with deposition in brain of senile plaques and neurofibrillary tangles. |
2019-11-20 |
2023-08-13 |
mouse |
| Lorenza Vitale, Valentina Serpieri, Mattia Lauriola, Allison Piovesan, Francesca Antonaros, Elena Cicchini, Chiara Locatelli, Guido Cocchi, Pierluigi Strippoli, Maria Caracaus. Human trisomy 21 fibroblasts rescue methotrexate toxic effect after treatment with 5-methyl-tetrahydrofolate and 5-formyl-tetrahydrofolate. Journal of cellular physiology. 2019-11-20. PMID:30667057. |
trisomy 21 causes down syndrome (ds), the most common human genetic disorder and the leading genetic cause of intellectual disability. |
2019-11-20 |
2023-08-13 |
human |
| Sandra Giménez, Laura Videla, Sergio Romero, Bessy Benejam, Susana Clos, Susana Fernández, Maribel Martínez, Maria Carmona-Iragui, Rosa M Antonijoan, Mercedes Mayos, Ana Fortuna, Patricia Peñacoba, Vicente Plaza, Ricardo S Osorio, Ram A Sharma, Ignasi Bardés, Anne-Sophie Rebillat, Alberto Lleó, Rafael Blesa, Sebastian Videla, Juan Forte. Prevalence of Sleep Disorders in Adults With Down Syndrome: A Comparative Study of Self-Reported, Actigraphic, and Polysomnographic Findings. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. vol 14. issue 10. 2019-11-19. PMID:30353801. |
sleep problems are often undetected in adults with down syndrome (ds). |
2019-11-19 |
2023-08-13 |
Not clear |
| Monique A L J Slaats, Dieter Loterman, Cedric van Holsbeke, Wim Vos, Kim Van Hoorenbeeck, Jan de Backer, Wilfried de Backer, Marek Wojciechowski, An Boudewyns, Stijn Verhuls. The Role of Functional Respiratory Imaging in Treatment Selection of Children With Obstructive Sleep Apnea and Down Syndrome. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. vol 14. issue 4. 2019-11-18. PMID:29609707. |
the complexity of the pathogenesis of obstructive sleep apnea (osa) in children with down syndrome (ds) is illustrated by a prevalence of residual osa after adenotonsillectomy. |
2019-11-18 |
2023-08-13 |
Not clear |
| S Manti, M C Cutrupi, C Cuppari, E Ferro, V Dipasquale, G Di Rosa, R Chimenz, M A La Rosa, A Valenti, V Salpietr. Inflammatory biomarkers and intellectual disability in patients with Down syndrome. Journal of intellectual disability research : JIDR. vol 62. issue 5. 2019-11-14. PMID:29349839. |
intellectual disability (id) is part of the down syndrome (ds) phenotypic spectrum, but the exact molecular pathophysiology of id in individuals with ds is not yet fully understood, with many research hypotheses still unproven. |
2019-11-14 |
2023-08-13 |
Not clear |
| A J Esbensen, E K Hoffma. Impact of sleep on executive functioning in school-age children with Down syndrome. Journal of intellectual disability research : JIDR. vol 62. issue 6. 2019-11-14. PMID:29696706. |
while children with down syndrome (ds) are at high risk for sleep problems, the impact of these sleep problems on executive functioning in school-age children with ds is less well documented. |
2019-11-14 |
2023-08-13 |
Not clear |
| L Roberts, J L Richmon. Using learning flexibly and remembering after a delay: understanding cognitive dysfunction in adults with Down syndrome. Journal of intellectual disability research : JIDR. vol 62. issue 6. 2019-11-14. PMID:29700883. |
episodic memory deficits are a characteristic of cognitive dysfunction in people with down syndrome (ds). |
2019-11-14 |
2023-08-13 |
Not clear |
| Agnieszka Skiba, Jakub Marchewka, Amadeusz Skiba, Szymon Podsiadło, Iwona Sulowska, Wiesław Chwała, Anna Marchewk. Evaluation of the Effectiveness of Nordic Walking Training in Improving the Gait of Persons with Down Syndrome. BioMed research international. vol 2019. 2019-11-14. PMID:31119179. |
people with down syndrome (ds) show dysfunction of gait, expressed by disturbed character of angular changes and values of the spatiotemporal parameters as compared to the physiological norm. |
2019-11-14 |
2023-08-13 |
human |
| P S Arango, A Aparicio, M Tenori. Developmental trajectories of children with Down syndrome by socio-economic status: the case of Latin America. Journal of intellectual disability research : JIDR. vol 62. issue 9. 2019-11-13. PMID:29984471. |
however, few studies have analysed this relationship regarding children with neurodevelopmental disorders such as down syndrome (ds). |
2019-11-13 |
2023-08-13 |
Not clear |
| A J Esbensen, E K Hoffman, R Shaffer, E Chen, L Patel, L Jacol. Reliability of parent report measures of behaviour in children with Down syndrome. Journal of intellectual disability research : JIDR. vol 62. issue 9. 2019-11-13. PMID:30022564. |
behavioural problems are common among children with down syndrome (ds). |
2019-11-13 |
2023-08-13 |
Not clear |
| C-C J J Chen, S D R Ringenbac. Walking performance in adolescents and young adults with Down syndrome: the role of obesity and sleep problems. Journal of intellectual disability research : JIDR. vol 62. issue 4. 2019-11-12. PMID:29484778. |
high prevalence of obesity and features of obstructive sleep apnea (osa) are major health issues in individuals with down syndrome (ds), and both may also affect adversely on their daily activities. |
2019-11-12 |
2023-08-13 |
Not clear |
| Marsha Michie, Megan Allys. Gene modification therapies: views of parents of people with Down syndrome. Genetics in medicine : official journal of the American College of Medical Genetics. vol 21. issue 2. 2019-11-12. PMID:29930393. |
the purpose of this study is to assess views of families with down syndrome (ds) regarding potential genome-based interventions. |
2019-11-12 |
2023-08-13 |
Not clear |
| Ramón Costa, Alejandra Gullón, Rosa De Miguel, Diego Real de Asúa, Azucena Bautista, Clara García, Carmen Suarez, Santos Castañeda, Fernando Moldenhaue. Bone Mineral Density Distribution Curves in Spanish Adults With Down Syndrome. Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry. vol 21. issue 4. 2019-11-11. PMID:29681439. |
according to reports from small-sized case series, adults with down syndrome (ds) appear to have lower bone mineral density (bmd) than the general population. |
2019-11-11 |
2023-08-13 |
Not clear |
| Ramón Costa, Alejandra Gullón, Rosa De Miguel, Diego Real de Asúa, Azucena Bautista, Clara García, Carmen Suarez, Santos Castañeda, Fernando Moldenhaue. Bone Mineral Density Distribution Curves in Spanish Adults With Down Syndrome. Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry. vol 21. issue 4. 2019-11-11. PMID:29681439. |
this is a retrospective study of 297 adults with ds from the adult down syndrome outpatient clinic of a tertiary care hospital in madrid, spain, who underwent a bone densitometry (hologic qdr-4500w), for clinical purposes between january 2010 and june 2015. |
2019-11-11 |
2023-08-13 |
Not clear |
| Grace O Mizuno, Yinxue Wang, Guilai Shi, Yizhi Wang, Junqing Sun, Stelios Papadopoulos, Gerard J Broussard, Elizabeth K Unger, Wenbin Deng, Jason Weick, Anita Bhattacharyya, Chao-Yin Chen, Guoqiang Yu, Loren L Looger, Lin Tia. Aberrant Calcium Signaling in Astrocytes Inhibits Neuronal Excitability in a Human Down Syndrome Stem Cell Model. Cell reports. vol 24. issue 2. 2019-11-07. PMID:29996097. |
down syndrome (ds) is a genetic disorder that causes cognitive impairment. |
2019-11-07 |
2023-08-13 |
human |
| C M Capio, T C T Mak, M A Tse, R S W Master. Fundamental movement skills and balance of children with Down syndrome. Journal of intellectual disability research : JIDR. vol 62. issue 3. 2019-10-31. PMID:29205624. |
in children with down syndrome (ds), fms development is delayed, which has been suggested to be associated with balance deficits. |
2019-10-31 |
2023-08-13 |
Not clear |
| Nermine H Am. Thyroid Disorders in Subjects with Down Syndrome: An Update. Acta bio-medica : Atenei Parmensis. vol 89. issue 1. 2019-10-29. PMID:29633736. |
down syndrome (ds) is the commonest chromosomal disorder among live born infants. |
2019-10-29 |
2023-08-13 |
human |
| Flávia Almeida Ribeiro Scalioni, Camila Faria Carrada, Carolina Castro Martins, Rosangela Almeida Ribeiro, Saul Martins Paiv. Periodontal disease in patients with Down syndrome: A systematic review. Journal of the American Dental Association (1939). vol 149. issue 7. 2019-10-29. PMID:29779565. |
the authors systematically reviewed the scientific evidence of an association between periodontal disease and down syndrome (ds). |
2019-10-29 |
2023-08-13 |
Not clear |