| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Simon A Lowe, Maria M Usowicz, James J L Hodg. Neuronal overexpression of Alzheimer's disease and Down's syndrome associated DYRK1A/minibrain gene alters motor decline, neurodegeneration and synaptic plasticity in Drosophila. Neurobiology of disease. vol 125. 2019-12-16. PMID:30703437. |
down syndrome (ds) is characterised by abnormal cognitive and motor development, and later in life by progressive alzheimer's disease (ad)-like dementia, neuropathology, declining motor function and shorter life expectancy. |
2019-12-16 |
2023-08-13 |
drosophila_melanogaster |
| Linda Bühl, Thomas Abel, Florian Wolf, Max Oberste, Wilhelm Bloch, Michael Hallek, Thomas Elter, Philipp Zimme. Feasibility and Potential Benefits of an Exercise Intervention in a Male With Down Syndrome Undergoing High-Dose Chemotherapy for Acute Lymphoblastic Leukemia: A Case Report. Integrative cancer therapies. vol 18. 2019-12-12. PMID:30795696. |
however, clinical trials have not yet integrated people with down syndrome (ds), although this disability is associated with an increased risk for hematological malignancies. |
2019-12-12 |
2023-08-13 |
Not clear |
| Sarah B Cairo, Lida I Zeinali, Sara K Berkelhamer, Carroll M Harmon, Sri O Rao, David H Rothstei. Down Syndrome and Postoperative Complications in Children Undergoing Intestinal Operations. Journal of pediatric surgery. vol 54. issue 9. 2019-12-11. PMID:30611525. |
this paper intends to evaluate the association between down syndrome (ds) and postoperative medical and surgical complications and inpatient postoperative mortality in pediatric patients undergoing intestinal operations. |
2019-12-11 |
2023-08-13 |
Not clear |
| Alessio Pini Prato, Rossella Arnoldi, Alberto Sgrò, Enrico Felici, Fabrizio Racca, Paolo Nozza, Narcisio Mariani, Manuela Mosconi, Cinzia Mazzola, Girolamo Mattiol. Hirschsprung disease and Down syndrome: From the reappraisal of risk factors to the impact of surgery. Journal of pediatric surgery. vol 54. issue 9. 2019-12-11. PMID:30814038. |
the association of hirschsprung disease (hscr) and down syndrome (ds) is not uncommon (hscr+ds). |
2019-12-11 |
2023-08-13 |
Not clear |
| Estelle Parizot, Rodolphe Dard, Nathalie Janel, François Vialar. Down syndrome and infertility: what support should we provide? Journal of assisted reproduction and genetics. vol 36. issue 6. 2019-12-11. PMID:31073724. |
down syndrome (ds) is the most common genetic disease at birth; on average, it affects 1 in 700 newborns. |
2019-12-11 |
2023-08-13 |
Not clear |
| Cody T Mowery, Jaime M Reyes, Lucia Cabal-Hierro, Kelly J Higby, Kristen L Karlin, Jarey H Wang, Robert J Kimmerling, Paloma Cejas, Klothilda Lim, Hubo Li, Takashi Furusawa, Henry W Long, David Pellman, Bjoern Chapuy, Michael Bustin, Scott R Manalis, Thomas F Westbrook, Charles Y Lin, Andrew A Lan. Trisomy of a Down Syndrome Critical Region Globally Amplifies Transcription via HMGN1 Overexpression. Cell reports. vol 25. issue 7. 2019-12-10. PMID:30428356. |
down syndrome (ds, trisomy 21) is associated with developmental abnormalities and increased leukemia risk. |
2019-12-10 |
2023-08-13 |
Not clear |
| Cody T Mowery, Jaime M Reyes, Lucia Cabal-Hierro, Kelly J Higby, Kristen L Karlin, Jarey H Wang, Robert J Kimmerling, Paloma Cejas, Klothilda Lim, Hubo Li, Takashi Furusawa, Henry W Long, David Pellman, Bjoern Chapuy, Michael Bustin, Scott R Manalis, Thomas F Westbrook, Charles Y Lin, Andrew A Lan. Trisomy of a Down Syndrome Critical Region Globally Amplifies Transcription via HMGN1 Overexpression. Cell reports. vol 25. issue 7. 2019-12-10. PMID:30428356. |
overexpression of the nucleosome binding protein hmgn1 (encoded on chr21q22) recapitulates transcriptional changes seen with triplication of a down syndrome critical region on distal chromosome 21, and hmgn1 is necessary for b cell phenotypes in ds models. |
2019-12-10 |
2023-08-13 |
Not clear |
| Mary Godfrey, Susan Hepburn, Deborah J Fidler, Tinashe Tapera, Fengqing Zhang, Cordelia Robinson Rosenberg, Nancy Raitano Le. Autism spectrum disorder (ASD) symptom profiles of children with comorbid Down syndrome (DS) and ASD: A comparison with children with DS-only and ASD-only. Research in developmental disabilities. vol 89. 2019-12-09. PMID:30959431. |
autism spectrum disorder (asd) symptom profiles of children with comorbid down syndrome (ds) and asd: a comparison with children with ds-only and asd-only. |
2019-12-09 |
2023-08-13 |
Not clear |
| Mary Godfrey, Susan Hepburn, Deborah J Fidler, Tinashe Tapera, Fengqing Zhang, Cordelia Robinson Rosenberg, Nancy Raitano Le. Autism spectrum disorder (ASD) symptom profiles of children with comorbid Down syndrome (DS) and ASD: A comparison with children with DS-only and ASD-only. Research in developmental disabilities. vol 89. 2019-12-09. PMID:30959431. |
down syndrome (ds) is associated with increased rates of autism spectrum disorder (asd), characterized by social-communicative impairments (soc-com) and repetitive behaviors and interests (rbi). |
2019-12-09 |
2023-08-13 |
Not clear |
| Annette M Lane, Marlette B Reed, Pamela Hawrani. Aging Individuals With Down Syndrome and Dementia as Teachers: Learnings from Staffin a Developmental Disability Program in Long-Term Care. Journal of gerontological nursing. vol 45. issue 5. 2019-12-09. PMID:31026328. |
older adults with down syndrome (ds) and dementia are an emerging sub-population. |
2019-12-09 |
2023-08-13 |
Not clear |
| Erik Orro, Kristi Alnek, Tiia Reimand, Koit Reimand, Oivi Uibo, Tiina Talvik, Kadri Haller-Kikkatalo, Kalle Kisand, Raivo Uib. Patients with down syndrome have increased prevalence of rheumatoid factor but not autoantibodies to anti-cyclic citrullinated peptide. Clinica chimica acta; international journal of clinical chemistry. vol 495. 2019-12-02. PMID:30890397. |
the association between down syndrome (ds), a genetic disorder resulting from trisomy of the 21st chromosome, and the autoantibodies of rheumatoid arthritis (ra) has been proposed but not unequivocally proven. |
2019-12-02 |
2023-08-13 |
Not clear |
| Mubashir Alavi Jusabani, Sakina Mehboob Rashid, Honest Herman Massawe, William Patrick Howlett, Marieke Cornelia Johanna Dekke. A case report of atlanto-axial instability in a Down Syndrome patient. Spinal cord series and cases. vol 4. 2019-11-28. PMID:30510773. |
down syndrome (ds)-also referred to as trisomy 21-is associated with multiple deformities affecting various systems of the body. |
2019-11-28 |
2023-08-13 |
Not clear |
| Samed Sati. Determination of mandibular morphology in a TURKISH population with Down syndrome using panoramic radiography. BMC oral health. vol 19. issue 1. 2019-11-27. PMID:30808330. |
down syndrome (ds) is by far the most common known chromosomal disorder. |
2019-11-27 |
2023-08-13 |
Not clear |
| Shariq Najeeb, Zohaib Khurshid, Fahad Siddiqui, Sana Zohaib, Muhammad Sohail Zafa. Outcomes of Dental Implant Therapy in Patients With Down Syndrome: A Systematic Review. The journal of evidence-based dental practice. vol 17. issue 4. 2019-11-26. PMID:29197433. |
patients with down syndrome (ds) require an earlier and more frequent tooth replacement than rest of the population. |
2019-11-26 |
2023-08-13 |
Not clear |
| I Descamps, C Fernandez, D Van Cleynenbreugel, Y Van Hoecke, L Mark. Dental care in children with Down syndrome: A questionnaire for Belgian dentists. Medicina oral, patologia oral y cirugia bucal. vol 24. issue 3. 2019-11-26. PMID:31011136. |
to date, research on the opinions of dentists on the oral health care of children with ds (down syndrome) is scarce. |
2019-11-26 |
2023-08-13 |
Not clear |
| Teresita Ferrary, Noelia Sanchez Ratto, Daniel Martinez, Mayra Alvarez, Maria Lis Bianchi, Maria Belen Benitez, Mariana Armada, Maite Echaide, Gabriela Scagnet, Betina Orma. Psychoprophylaxis for oral conscious sedation for dental care in Down syndrome adults with behavioral disorder. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry. vol 39. issue 4. 2019-11-26. PMID:31050376. |
down syndrome (ds) presents with prevalent diseases in the oral cavity and the need of constant dental care and follow-up. |
2019-11-26 |
2023-08-13 |
Not clear |
| Maria Caracausi, Veronica Ghini, Chiara Locatelli, Martina Mericio, Allison Piovesan, Francesca Antonaros, Maria Chiara Pelleri, Lorenza Vitale, Rosa Anna Vacca, Federica Bedetti, Maria Chiara Mimmi, Claudio Luchinat, Paola Turano, Pierluigi Strippoli, Guido Cocch. Plasma and urinary metabolomic profiles of Down syndrome correlate with alteration of mitochondrial metabolism. Scientific reports. vol 8. issue 1. 2019-11-25. PMID:29445163. |
down syndrome (ds) is caused by the presence of a supernumerary copy of the human chromosome 21 (hsa21) and is the most frequent genetic cause of intellectual disability (id). |
2019-11-25 |
2023-08-13 |
human |
| Rosalyn Hithersay, Carla M Startin, Sarah Hamburg, Kin Y Mok, John Hardy, Elizabeth M C Fisher, Victor L J Tybulewicz, Dean Nizetic, André Strydo. Association of Dementia With Mortality Among Adults With Down Syndrome Older Than 35 Years. JAMA neurology. vol 76. issue 2. 2019-11-25. PMID:30452522. |
this work quantifies the fatal burden of dementia associated with alzheimer disease in individuals with down syndrome (ds). |
2019-11-25 |
2023-08-13 |
Not clear |
| Valerie Seror, Olivier L'Haridon, Laurence Bussières, Valérie Malan, Nicolas Fries, Michel Vekemans, Laurent J Salomon, Yves Vill. Women's Attitudes Toward Invasive and Noninvasive Testing When Facing a High Risk of Fetal Down Syndrome. JAMA network open. vol 2. issue 3. 2019-11-25. PMID:30924894. |
noninvasive prenatal testing (nipt) using cell-free dna in maternal blood is increasingly common compared with invasive testing (it) in routine antenatal detection of down syndrome (ds). |
2019-11-25 |
2023-08-13 |
Not clear |
| Tomoka Okamura, Yousuke Washio, Junko Yoshimoto, Kazumasa Tani, Hirokazu Tsukahara, Akira Shimad. Exchange Transfusion and Cytarabine for Transient Abnormal Myelopoiesis in Hydrops Fetalis. Acta medica Okayama. vol 73. issue 2. 2019-11-25. PMID:31015754. |
most cases of transient abnormal myelopoiesis (tam) in neonates with down syndrome (ds) resolve spontaneously; however, ds-tam neonates with hydrops fetalis (hf) show poor clinical outcomes. |
2019-11-25 |
2023-08-13 |
Not clear |