| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pankaj Bhatia, Nirmal Sing. Homocysteine excess: delineating the possible mechanism of neurotoxicity and depression. Fundamental & clinical pharmacology. vol 29. issue 6. 2016-10-11. PMID:26376956. |
serotonin (5-ht), due to genetic alteration in key enzyme mthfr in the homocysteine metabolism pathway that leads to depression. |
2016-10-11 |
2023-08-13 |
Not clear |
| Dasiel O Borroto-Escuela, Alexander O Tarakanov, Kjell Fux. FGFR1-5-HT1A Heteroreceptor Complexes: Implications for Understanding and Treating Major Depression. Trends in neurosciences. vol 39. issue 1. 2016-10-07. PMID:26687454. |
the serotonin and neurotrophic factor hypotheses of depression are well known. |
2016-10-07 |
2023-08-13 |
Not clear |
| Ravi Bansal, Bradley S Peterson, Jay Gingrich, Xuejun Hao, Zagaa Odgerel, Virginia Warner, Priya J Wickramaratne, Ardesheer Talati, Mark Ansorge, Alan S Brown, Andre Sourander, Myrna M Weissma. Serotonin signaling modulates the effects of familial risk for depression on cortical thickness. Psychiatry research. Neuroimaging. vol 248. 2016-10-07. PMID:26774425. |
serotonin signaling modulates the effects of familial risk for depression on cortical thickness. |
2016-10-07 |
2023-08-13 |
Not clear |
| Wanhong Zuo, Yong Zhang, Guiqin Xie, Danielle Gregor, Alex Bekker, Jiang-Hong Y. Serotonin stimulates lateral habenula via activation of the post-synaptic serotonin 2/3 receptors and transient receptor potential channels. Neuropharmacology. vol 101. 2016-10-05. PMID:26471419. |
these results demonstrate that the reciprocal connection between the lhb and the 5-ht system highlights a key role for 5-ht stimulation of lhb neurons that may be important in the pathogenesis of depression. |
2016-10-05 |
2023-08-13 |
rat |
| Pellegrino Lippiello, Eriola Hoxha, Luisa Speranza, Floriana Volpicelli, Angela Ferraro, Marcello Leopoldo, Enza Lacivita, Carla Perrone-Capano, Filippo Tempia, Maria Concetta Miniac. The 5-HT7 receptor triggers cerebellar long-term synaptic depression via PKC-MAPK. Neuropharmacology. vol 101. 2016-10-05. PMID:26482421. |
the 5-ht7 receptor (5-ht7r) mediates important physiological effects of serotonin, such as memory and emotion, and is emerging as a therapeutic target for the treatment of cognitive disorders and depression. |
2016-10-05 |
2023-08-13 |
mouse |
| Yogendra Raj Pandey, Shobhit Kumar, Bijay Kumar Gupta, Javed Ali, Sanjula Baboot. Intranasal delivery of paroxetine nanoemulsion via the olfactory region for the management of depression: formulation, behavioural and biochemical estimation. Nanotechnology. vol 27. issue 2. 2016-10-05. PMID:26629830. |
paroxetine is a selective serotonin reuptake inhibitor (ssri) and is used for the treatment of depression and anxiety problems, but suffers from the drawback of poor oral bioavailability (less than 50%) due to its extensive first pass metabolism. |
2016-10-05 |
2023-08-13 |
rat |
| Jian-Chun Zong, Xing Wang, Xiang Zhou, Chen Wang, Liang Chen, Liang-Jun Yin, Bai-Cheng He, Zhong-Liang Den. Gut-derived serotonin induced by depression promotes breast cancer bone metastasis through the RUNX2/PTHrP/RANKL pathway in mice. Oncology reports. vol 35. issue 2. 2016-09-30. PMID:26573960. |
gut-derived serotonin induced by depression promotes breast cancer bone metastasis through the runx2/pthrp/rankl pathway in mice. |
2016-09-30 |
2023-08-13 |
mouse |
| Jian-Chun Zong, Xing Wang, Xiang Zhou, Chen Wang, Liang Chen, Liang-Jun Yin, Bai-Cheng He, Zhong-Liang Den. Gut-derived serotonin induced by depression promotes breast cancer bone metastasis through the RUNX2/PTHrP/RANKL pathway in mice. Oncology reports. vol 35. issue 2. 2016-09-30. PMID:26573960. |
in conclusion, depression promotes breast cancer bone metastasis partly through increasing levels of gut‑derived serotonin. |
2016-09-30 |
2023-08-13 |
mouse |
| Jian-Chun Zong, Xing Wang, Xiang Zhou, Chen Wang, Liang Chen, Liang-Jun Yin, Bai-Cheng He, Zhong-Liang Den. Gut-derived serotonin induced by depression promotes breast cancer bone metastasis through the RUNX2/PTHrP/RANKL pathway in mice. Oncology reports. vol 35. issue 2. 2016-09-30. PMID:26573960. |
activation of runx2 in breast cancer cells by circulating serotonin appears to dissociate coupling between osteoblasts and osteoclasts, suggesting that the suppression of gut‑derived serotonin decreases the rate of breast cancer bone metastasis induced by depression. |
2016-09-30 |
2023-08-13 |
mouse |
| Deepthi Konda, Laxmisha Chandrashekar, Medha Rajappa, Shivanand Kattimani, Devinder Mohan Thappa, P H Ananthanarayana. Serotonin and interleukin-6: Association with pruritus severity, sleep quality and depression severity in Prurigo Nodularis. Asian journal of psychiatry. vol 17. 2016-09-28. PMID:26277226. |
serotonin and interleukin-6: association with pruritus severity, sleep quality and depression severity in prurigo nodularis. |
2016-09-28 |
2023-08-13 |
Not clear |
| Deepthi Konda, Laxmisha Chandrashekar, Medha Rajappa, Shivanand Kattimani, Devinder Mohan Thappa, P H Ananthanarayana. Serotonin and interleukin-6: Association with pruritus severity, sleep quality and depression severity in Prurigo Nodularis. Asian journal of psychiatry. vol 17. 2016-09-28. PMID:26277226. |
hence, we undertook to assess the association between quality of sleep, depression, pruritus severity in cases of pn and to assess association of serum serotonin, interleukin (il)-6 with sleep, depression and pruritus severity. |
2016-09-28 |
2023-08-13 |
Not clear |
| Deepthi Konda, Laxmisha Chandrashekar, Medha Rajappa, Shivanand Kattimani, Devinder Mohan Thappa, P H Ananthanarayana. Serotonin and interleukin-6: Association with pruritus severity, sleep quality and depression severity in Prurigo Nodularis. Asian journal of psychiatry. vol 17. 2016-09-28. PMID:26277226. |
cases had significantly higher percentage of depression, a higher score of depression severity, higher serum il-6 level and lower serum serotonin levels. |
2016-09-28 |
2023-08-13 |
Not clear |
| Deepthi Konda, Laxmisha Chandrashekar, Medha Rajappa, Shivanand Kattimani, Devinder Mohan Thappa, P H Ananthanarayana. Serotonin and interleukin-6: Association with pruritus severity, sleep quality and depression severity in Prurigo Nodularis. Asian journal of psychiatry. vol 17. 2016-09-28. PMID:26277226. |
pn is characterized by higher il-6 and lower serotonin and greater depression severity than healthy controls. |
2016-09-28 |
2023-08-13 |
Not clear |
| Rui Xue, Xin-Hua He, Li Yuan, Hong-Xia Chen, Li-Ming Zhang, Zheng Yong, Gang Yu, Shi-Yong Fan, Yun-Feng Li, Bo-Hua Zhong, You-Zhi Zhan. Effects of 071031B, a novel serotonin and norepinephrine reuptake inhibitor, on monoamine system in mice and rats. Journal of pharmacological sciences. vol 130. issue 1. 2016-09-26. PMID:26318675. |
our previous study indicated that 071031b, a novel potential serotonin and norepinephrine reuptake inhibitor, showed robust antidepressant activity in multiple depression models, and could simultaneously inhibit 5-ht and ne reuptake in vitro. |
2016-09-26 |
2023-08-13 |
mouse |
| Ti-Fei Yuan, Flávia Paes, Oscar Arias-Carrión, Nuno Barbosa Ferreira Rocha, Alberto Souza de Sá Filho, Sergio Machad. Neural Mechanisms of Exercise: Anti-Depression, Neurogenesis, and Serotonin Signaling. CNS & neurological disorders drug targets. vol 14. issue 10. 2016-09-26. PMID:26556077. |
depression is associated with decreased serotonin metabolism and functioning in the central nervous system, evidenced by both animal models of depression and clinical patient studies. |
2016-09-26 |
2023-08-13 |
Not clear |
| Shunji Suzuk. Relapse of depression during pregnancy and postpartum periods in Japanese women associated with self-interruption of their medications: Selective serotonin reuptake inhibitors. Asian journal of psychiatry. vol 18. 2016-09-26. PMID:26603370. |
relapse of depression during pregnancy and postpartum periods in japanese women associated with self-interruption of their medications: selective serotonin reuptake inhibitors. |
2016-09-26 |
2023-08-13 |
Not clear |
| Kelly Ann Scanlon, Robert Stoppacher, Lee M Blum, Samantha J Starke. Comprehensive Duloxetine Analysis in a Fatal Overdose. Journal of analytical toxicology. vol 40. issue 2. 2016-09-26. PMID:26662354. |
duloxetine is a second-generation selective serotonin and norepinephrine reuptake inhibitor used primarily for the treatment of depression. |
2016-09-26 |
2023-08-13 |
Not clear |
| Shinpei Nonen, Masaki Kato, Yoshiteru Takekita, Masataka Wakeno, Shiho Sakai, Alessandro Serretti, Toshihiko Kinoshit. Polymorphism of rs3813034 in Serotonin Transporter Gene SLC6A4 Is Associated With the Selective Serotonin and Serotonin-Norepinephrine Reuptake Inhibitor Response in Depressive Disorder: Sequencing Analysis of SLC6A4. Journal of clinical psychopharmacology. vol 36. issue 1. 2016-09-26. PMID:26674707. |
selective serotonin and serotonin-norepinephrine reuptake inhibitors (ssri/snri) are commonly used for treating major depression. |
2016-09-26 |
2023-08-13 |
Not clear |
| Heather Tran, Adelaide S Rob. SSRI use during pregnancy. Seminars in perinatology. vol 39. issue 7. 2016-09-22. PMID:26428019. |
one of the most important topics covered during that 2-day conference was major depression (mdd) and the use of serotonin selective reuptake inhibitors (ssris). |
2016-09-22 |
2023-08-13 |
Not clear |
| Joo Hwan Roh, Il-Gyu Ko, Sung-Eun Kim, Jae-Min Lee, Eun-Sang Ji, Ju Ho Kim, Hyun-Kyung Chang, Seung Kyu Lee, Khae Hawn Ki. Treadmill exercise ameliorates intracerebral hemorrhage-induced depression in rats. Journal of exercise rehabilitation. vol 12. issue 4. 2016-09-22. PMID:27656626. |
western blot analysis for 5-hydroxy-tryptamine (5-ht, serotonin) and tryptophan hydroxylase (tph) in the dorsal raphe was also conducted for biomarkers of depression. |
2016-09-22 |
2023-08-13 |
rat |