| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Vignau, L Karila, O Costisella, V Canv. [Hepatitis C, interferon a and depression: main physiopathologic hypothesis]. L'Encephale. vol 31. issue 3. 2005-10-25. PMID:16142050. |
second, keeping in mind that serotonin is a monoaminergic neurotransmitter classically involved in depression pathophysiology, other works have demonstrated that ifnalpha modulates the peripheral activity of indolamine-dioxygenase -- a regulating enzyme of serotonin metabolism -- possibly through lymphocyte t cd4 activation. |
2005-10-25 |
2023-08-12 |
human |
| J Vignau, L Karila, O Costisella, V Canv. [Hepatitis C, interferon a and depression: main physiopathologic hypothesis]. L'Encephale. vol 31. issue 3. 2005-10-25. PMID:16142050. |
moreover, selective inhibitors of serotonin transporters are effective to treat or prevent depression caused by ifnalpha. |
2005-10-25 |
2023-08-12 |
human |
| Kazuya Iwamoto, Noriaki Nakatani, Miki Bundo, Takeo Yoshikawa, Tadafumi Kat. Altered RNA editing of serotonin 2C receptor in a rat model of depression. Neuroscience research. vol 53. issue 1. 2005-10-20. PMID:16005997. |
altered rna editing of serotonin 2c receptor in a rat model of depression. |
2005-10-20 |
2023-08-12 |
rat |
| Kazuya Iwamoto, Noriaki Nakatani, Miki Bundo, Takeo Yoshikawa, Tadafumi Kat. Altered RNA editing of serotonin 2C receptor in a rat model of depression. Neuroscience research. vol 53. issue 1. 2005-10-20. PMID:16005997. |
altered rna editing of serotonin 2c receptor (htr2c) has been suggested to be involved in the pathophysiology of major depression. |
2005-10-20 |
2023-08-12 |
rat |
| David Seck. Depression: more than just serotonin. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. vol 172. issue 12. 2005-10-19. PMID:15939910. |
depression: more than just serotonin. |
2005-10-19 |
2023-08-12 |
Not clear |
| Levent Ozçakar, Ahmet Mesut Onat, Semra Ulusoy Kaymak, Kemal Ureten, Ayşen Akinc. Selective serotonin reuptake inhibitors in familial Mediterranean fever: are we treating depression or inflammation? Rheumatology international. vol 25. issue 4. 2005-10-18. PMID:15449025. |
selective serotonin reuptake inhibitors in familial mediterranean fever: are we treating depression or inflammation? |
2005-10-18 |
2023-08-12 |
Not clear |
| Jeff Q Bostic, David H Rubin, Jefferson Prince, Steven Schlozma. Treatment of depression in children and adolescents. Journal of psychiatric practice. vol 11. issue 3. 2005-10-17. PMID:15920388. |
controlled antidepressant trials in juveniles with depression provide some support for the use of some selective serotonin reuptake inhibitors and little support for atypical antidepressants, tricyclic antidepressants, or monoamine oxidase inhibitors. |
2005-10-17 |
2023-08-12 |
Not clear |
| Raymond P Ward, Marcelo Kugelma. Using pegylated interferon and ribavirin to treat patients with chronic hepatitis C. American family physician. vol 72. issue 4. 2005-10-13. PMID:16127955. |
depression also can be caused or exacerbated by these medicines and may require treatment with a selective serotonin reuptake inhibitor, comanagement with psychiatry, or cessation of pegylated interferon and ribavirin treatment. |
2005-10-13 |
2023-08-12 |
Not clear |
| L Arboreliu. 5-HT1A receptor antagonists as putative adjuvants to antidepressants: preclinical and clinical evidence. IDrugs : the investigational drugs journal. vol 2. issue 2. 2005-10-13. PMID:16160947. |
recently, the hypothesis was advanced that addition of a serotonin 1a (5-ht1a) receptor antagonist may shorten the latency to antidepressant action of selective serotonin reuptake inhibitors (ssris) as well as increase their efficacy in the treatment of depression. |
2005-10-13 |
2023-08-12 |
Not clear |
| Annique Schins, Marinus Van Kroonenburgh, Koen Van Laere, Hugo D'haenen, Richel Lousberg, Harry Crijns, Jos Eersels, Adriaan Honi. Increased cerebral serotonin-2A receptor binding in depressed patients with myocardial infarction. Psychiatry research. vol 139. issue 2. 2005-10-11. PMID:15967646. |
serotonin (5-ht) has been implicated in the pathophysiology of depression. |
2005-10-11 |
2023-08-12 |
human |
| Annique Schins, Marinus Van Kroonenburgh, Koen Van Laere, Hugo D'haenen, Richel Lousberg, Harry Crijns, Jos Eersels, Adriaan Honi. Increased cerebral serotonin-2A receptor binding in depressed patients with myocardial infarction. Psychiatry research. vol 139. issue 2. 2005-10-11. PMID:15967646. |
both post-mi depression and mi seem to be associated with changes in 5-ht(2a) receptor binding. |
2005-10-11 |
2023-08-12 |
human |
| Madhukar H Trived. The link between depression and physical symptoms. Primary care companion to the Journal of clinical psychiatry. vol 6. issue Suppl 1. 2005-10-11. PMID:16001092. |
physical pain and depression have a deeper biological connection than simple cause and effect; the neurotransmitters that influence both pain and mood are serotonin and norepinephrine. |
2005-10-11 |
2023-08-12 |
Not clear |
| G Caliendo, V Santagada, E Perissutti, F Fiorin. Derivatives as 5HT1A receptor ligands--past and present. Current medicinal chemistry. vol 12. issue 15. 2005-10-11. PMID:16029144. |
serotonin is a neuromediator, well-know for its implication in mood regulation, anxiety, depression and, insomnia as well as in normal human function such as sleep, sexual activity and appetite. |
2005-10-11 |
2023-08-12 |
human |
| David T Wong, Kenneth W Perry, Frank P Bymaste. Case history: the discovery of fluoxetine hydrochloride (Prozac). Nature reviews. Drug discovery. vol 4. issue 9. 2005-10-07. PMID:16121130. |
in the early 1970s, evidence of the role of serotonin (5-hydroxytryptamine or 5-ht) in depression began to emerge and the hypothesis that enhancing 5-ht neurotransmission would be a viable mechanism to mediate antidepressant response was put forward. |
2005-10-07 |
2023-08-12 |
Not clear |
| J F F Lekkerkerker, A F A M Schobben, J T van Dissel, Y A Hekster, A W Hoes, G J Mulder, C Neef, M F Peeters, J M van Ree, C F H Rosmalen, H Schellekens, J H M Schellens, J Silberbusc. [Selective serotonin reuptake inhibitors (SSRI's) are not indicated for children and adolescents with depression]. Nederlands tijdschrift voor geneeskunde. vol 149. issue 33. 2005-10-06. PMID:16128186. |
[selective serotonin reuptake inhibitors (ssri's) are not indicated for children and adolescents with depression]. |
2005-10-06 |
2023-08-12 |
Not clear |
| Jörn Lötsch, Carsten Skarke, Andreas Schneider, Thomas Hummel, Gerd Geisslinge. The 5-hydroxytryptamine 4 receptor agonist mosapride does not antagonize morphine-induced respiratory depression. Clinical pharmacology and therapeutics. vol 78. issue 3. 2005-09-27. PMID:16153398. |
the 5-hydroxytryptamine 4 receptor agonist mosapride does not antagonize morphine-induced respiratory depression. |
2005-09-27 |
2023-08-12 |
rat |
| Jörn Lötsch, Carsten Skarke, Andreas Schneider, Thomas Hummel, Gerd Geisslinge. The 5-hydroxytryptamine 4 receptor agonist mosapride does not antagonize morphine-induced respiratory depression. Clinical pharmacology and therapeutics. vol 78. issue 3. 2005-09-27. PMID:16153398. |
on the basis of experiments in rats, serotonin 4 receptor (5-hydroxytryptamine 4 [5-ht4]) agonists have been proposed as a novel therapeutic strategy for the selective treatment of respiratory depression caused by opioids while leaving analgesic effects unaffected. |
2005-09-27 |
2023-08-12 |
rat |
| Linda Booij, A J Willem Van der Does, P M Judith Haffmans, Wim J Riede. Acute tryptophan depletion in depressed patients treated with a selective serotonin-noradrenalin reuptake inhibitor: augmentation of antidepressant response? Journal of affective disorders. vol 86. issue 2-3. 2005-09-23. PMID:15935252. |
it has frequently been demonstrated that experimental lowering of serotonin (5-ht) neurotransmission by acute tryptophan depletion (atd) induces a transient depressed mood in 50-60% of patients treated with a selective serotonin reuptake inhibitor (ssri) who are in remission from depression. |
2005-09-23 |
2023-08-12 |
Not clear |
| D E Ra. CINP 2000 - Collegium Internationale Neuro-Psychopharmacologicum 22nd Congress. IDrugs : the investigational drugs journal. vol 3. issue 9. 2005-09-20. PMID:16049859. |
reboxetine (pharmacia & upjohn ab), having a far greater selectivity for norepinephrine reuptake inhibition than for serotonin or dopamine reuptake, is of particular value in treating depression. |
2005-09-20 |
2023-08-12 |
Not clear |
| Angela J Grippo, Nicole R Sullivan, Katerina J Damjanoska, James W Crane, Gonzalo A Carrasco, Ju Shi, Zhuo Chen, Francisca Garcia, Nancy A Muma, Louis D Van de Ka. Chronic mild stress induces behavioral and physiological changes, and may alter serotonin 1A receptor function, in male and cycling female rats. Psychopharmacology. vol 179. issue 4. 2005-09-15. PMID:15619113. |
interactions among stress, serotonin 1a (5-ht(1a)) receptors, and the hypothalamic-pituitary-adrenocortical (hpa) system have been proposed to influence the development of depression in humans. |
2005-09-15 |
2023-08-12 |
rat |