| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daphne Voineskos, Daniel M Blumberger, Nigel C Rogasch, Reza Zomorrodi, Faranak Farzan, George Foussias, Tarek K Rajji, Zafiris J Daskalaki. Neurophysiological effects of repetitive transcranial magnetic stimulation (rTMS) in treatment resistant depression. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 132. issue 9. 2021-11-11. PMID:34167891. |
we previously identified neurophysiological markers in depression (n45 and n100) of gaba receptor mediated inhibition. |
2021-11-11 |
2023-08-13 |
Not clear |
| Maria Ironside, Amelia D Moser, Laura M Holsen, Chun S Zuo, Fei Du, Sarah Perlo, Christine E Richards, Jessica M Duda, Xi Chen, Lisa D Nickerson, Kaylee E Null, Nara Nascimento, David J Crowley, Madhusmita Misra, Jill M Goldstein, Diego A Pizzagall. Reductions in rostral anterior cingulate GABA are associated with stress circuitry in females with major depression: a multimodal imaging investigation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 12. 2021-11-10. PMID:34363015. |
reductions in rostral anterior cingulate gaba are associated with stress circuitry in females with major depression: a multimodal imaging investigation. |
2021-11-10 |
2023-08-13 |
Not clear |
| Maria Ironside, Amelia D Moser, Laura M Holsen, Chun S Zuo, Fei Du, Sarah Perlo, Christine E Richards, Jessica M Duda, Xi Chen, Lisa D Nickerson, Kaylee E Null, Nara Nascimento, David J Crowley, Madhusmita Misra, Jill M Goldstein, Diego A Pizzagall. Reductions in rostral anterior cingulate GABA are associated with stress circuitry in females with major depression: a multimodal imaging investigation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 12. 2021-11-10. PMID:34363015. |
collectively, these findings indicate that reduced gaba in females with mdd was associated with connectivity differences within and across key networks implicated in depression. |
2021-11-10 |
2023-08-13 |
Not clear |
| Honglei Yin, Jia Guo, Qianqian Xin, Shuqiong Zheng, Xiang Xue, Enze Li, Ting Liu, Na Yan, John Keilp, J John Man. Influence of the GABA Receptor Subunit Gene Polymorphism and Childhood Sexual Abuse on Processing Speed in Major Depression and Suicide Attempt. Frontiers in psychiatry. vol 12. 2021-11-05. PMID:34733184. |
influence of the gaba receptor subunit gene polymorphism and childhood sexual abuse on processing speed in major depression and suicide attempt. |
2021-11-05 |
2023-08-13 |
Not clear |
| Y Li, X Feng, H Ren, H Huang, Yu Wang, S Y. Low-Dose Ozone Therapy Improves Sleep Quality in Patients with Insomnia and Coronary Heart Disease by Elevating Serum BDNF and GABA. Bulletin of experimental biology and medicine. vol 170. issue 4. 2021-11-04. PMID:33713235. |
the 3-month course of low-dose ozone therapy significantly elevated serum bdnf and gaba in chd patients with insomnia and improved parameters of anxiety, depression, and sleep quality according to hospital anxiety and depression scale (hads), pittsburgh sleep quality index (psqi), and self-rating scale of sleep (srss). |
2021-11-04 |
2023-08-13 |
Not clear |
| Shijing Wang, Francesco Leri, Sakina J Rizv. Anhedonia as a central factor in depression: Neural mechanisms revealed from preclinical to clinical evidence. Progress in neuro-psychopharmacology & biological psychiatry. vol 110. 2021-11-01. PMID:33631251. |
as well, serotonin, norepinephrine, opioids, glutamate, gamma aminobutyric acid (gaba), and acetylcholine are also involved in anhedonia, and medications targeting these systems may also potentially normalize reward processing in depression. |
2021-11-01 |
2023-08-13 |
Not clear |
| Kate E M Godfrey, Suresh D Muthukumaraswamy, Cathy M Stinear, Nicholas Hoe. Effect of rTMS on GABA and glutamate levels in treatment-resistant depression: An MR spectroscopy study. Psychiatry research. Neuroimaging. vol 317. 2021-10-25. PMID:34479176. |
effect of rtms on gaba and glutamate levels in treatment-resistant depression: an mr spectroscopy study. |
2021-10-25 |
2023-08-13 |
Not clear |
| Martin Nørgaard, Vincent Beliveau, Melanie Ganz, Claus Svarer, Lars H Pinborg, Sune H Keller, Peter S Jensen, Douglas N Greve, Gitte M Knudse. A high-resolution in vivo atlas of the human brain's benzodiazepine binding site of GABA NeuroImage. vol 232. 2021-10-14. PMID:33610745. |
a high-resolution in vivo atlas of the human brain's benzodiazepine binding site of gaba gamma-aminobutyric acid (gaba) is the main inhibitory neurotransmitter in the human brain and plays a key role in several brain functions and neuropsychiatric disorders such as anxiety, epilepsy, and depression. |
2021-10-14 |
2023-08-13 |
human |
| Balwinder Singh, John D Port, Jennifer L Vande Voort, Brandon J Coombes, Jennifer R Geske, Ian R Lanza, Robert J Morgan, Mark A Fry. A preliminary study of the association of increased anterior cingulate gamma-aminobutyric acid with remission of depression after ketamine administration. Psychiatry research. vol 301. 2021-10-14. PMID:33933839. |
a preliminary study of the association of increased anterior cingulate gamma-aminobutyric acid with remission of depression after ketamine administration. |
2021-10-14 |
2023-08-13 |
Not clear |
| Balwinder Singh, John D Port, Jennifer L Vande Voort, Brandon J Coombes, Jennifer R Geske, Ian R Lanza, Robert J Morgan, Mark A Fry. A preliminary study of the association of increased anterior cingulate gamma-aminobutyric acid with remission of depression after ketamine administration. Psychiatry research. vol 301. 2021-10-14. PMID:33933839. |
gamma-aminobutyric acid (gaba) and glutamate neurotransmission have been implicated in the pathophysiology of depression and mechanistically linked to ketamine's antidepressant response. |
2021-10-14 |
2023-08-13 |
Not clear |
| Adam Włodarczyk, Wiesław J Cubała, Mateusz Stawick. Ketogenic diet for depression: A potential dietary regimen to maintain euthymia? Progress in neuro-psychopharmacology & biological psychiatry. vol 109. 2021-10-07. PMID:33497756. |
moreover, positive allosteric gaba modulators (i.e benzodiazepines) are widely prescribed to alleviate depression symptoms, but their use needs to be limited, as it can lead to addiction. |
2021-10-07 |
2023-08-13 |
Not clear |
| Amber N Edinoff, Amira S Odisho, Kendall Lewis, Amir Kaskas, Grace Hunt, Elyse M Cornett, Alan D Kaye, Adam Kaye, John Morgan, P Scott Barrilleaux, David Lewis, Omar Viswanath, Ivan Urit. Brexanolone, a GABA Frontiers in psychiatry. vol 12. 2021-10-02. PMID:34594247. |
brexanolone, a gaba postpartum depression (ppd) is one of the three major categories on the spectrum of postpartum psychiatric syndromes. |
2021-10-02 |
2023-08-13 |
Not clear |
| Jonas Persson, Anders Wall, Jan Weis, Malin Gingnell, Gunnar Antoni, Mark Lubberink, Robert Bodé. Inhibitory and excitatory neurotransmitter systems in depressed and healthy: A positron emission tomography and magnetic resonance spectroscopy study. Psychiatry research. Neuroimaging. vol 315. 2021-09-27. PMID:34246046. |
the gamma-aminobutyric acid (gaba) and glutamate (glu) neurotransmitter systems are implicated in depression. |
2021-09-27 |
2023-08-13 |
Not clear |
| Shuxuan Lyu, Yuan Guo, Li Zhang, Yong Wang, Guoyi Tang, Ruotong Li, Jie Yang, Shasha Gao, Borui Ma, Jian Li. Blockade of GABA transporter-1 and GABA transporter-3 in the lateral habenula improves depressive-like behaviors in a rat model of Parkinson's disease. Neuropharmacology. vol 181. 2021-09-23. PMID:33096108. |
at present, it is unknown how gaba transporter (gat) in the lhb affects depressive-like behaviors, particularly in parkinson's disease (pd)-related depression. |
2021-09-23 |
2023-08-13 |
rat |
| Toshifumi Tomoda, Akiko Sumitomo, Rammohan Shukla, Yuki Hirota-Tsuyada, Hitoshi Miyachi, Hyunjung Oh, Leon French, Etienne Sibill. BDNF controls GABA Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2021-09-16. PMID:34341497. |
here we first show that reduced bdnf and gaba also co-occur with attenuated autophagy in human depression. |
2021-09-16 |
2023-08-13 |
mouse |
| Demet Aydogan Kirmizi, Emre Baser, Taylan Onat, Melike Demir Caltekin, Ethem Serdar Yalvac, Mustafa Kara, Ayse Yesim Gocme. Sexual function and depression in polycystic ovary syndrome: Is it associated with inflammation and neuromodulators? Neuropeptides. vol 84. 2021-09-06. PMID:33120204. |
metabolic and endocrine parameters, interleukin (il)-1β, il-6, tnfα, γ-aminobutyric acid (gaba), glutamate, brain-derived neurotrophic factor (bdnf) serum levels, beck depression index (bdi) and female sexual function index (fsfi) scores of the patients were compared between the groups. |
2021-09-06 |
2023-08-13 |
human |
| Demet Aydogan Kirmizi, Emre Baser, Taylan Onat, Melike Demir Caltekin, Ethem Serdar Yalvac, Mustafa Kara, Ayse Yesim Gocme. Sexual function and depression in polycystic ovary syndrome: Is it associated with inflammation and neuromodulators? Neuropeptides. vol 84. 2021-09-06. PMID:33120204. |
glutamate, tnfα, il-1β, and il-6 values were higher whereas gaba and bdnf values were lower in pateints with moderate and severe depression (p < 0.05). |
2021-09-06 |
2023-08-13 |
human |
| Hua-Wei Zou, Zi-Lin Li, Xiao-Yuan Jing, Yan Wang, Ying-Juan Liu, Lai-Fu L. The GABA(B1) receptor within the infralimbic cortex is implicated in stress resilience and vulnerability in mice. Behavioural brain research. vol 406. 2021-09-02. PMID:33727046. |
preclinical studies suggest that gaba(b) receptors (gaba(b1) and gaba(b2)) are potential targets for the treatment of major depression. |
2021-09-02 |
2023-08-13 |
mouse |
| Hui-Qin Wang, Zhen-Zhen Wang, Nai-Hong Che. The receptor hypothesis and the pathogenesis of depression: Genetic bases and biological correlates. Pharmacological research. vol 167. 2021-08-19. PMID:33711432. |
this review summarizes the pathogenesis of depression from six of the most related receptors and their associated genes, including n-methyl-d-aspartate receptor, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor, glucocorticoid receptor, 5-hydroxytryptamine receptor, gaba |
2021-08-19 |
2023-08-13 |
human |
| Benjamin K Lau, Ciaran Murphy-Royal, Manpreet Kaur, Min Qiao, Jaideep S Bains, Grant R Gordon, Stephanie L Borglan. Obesity-induced astrocyte dysfunction impairs heterosynaptic plasticity in the orbitofrontal cortex. Cell reports. vol 36. issue 7. 2021-08-18. PMID:34407401. |
here, we show that extended access to a cafeteria diet impairs astrocyte glutamate clearance, which leads to a heterosynaptic depression of gaba transmission onto pyramidal neurons of the ofc. |
2021-08-18 |
2023-08-13 |
Not clear |