| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kim H Tran, Jessica Luki, Sarah Hanstock, Christopher C Hanstock, Peter Seres, Katherine Aitchison, Tami Shandro, Jean-Michel Le Melled. The impact of matching for reproductive status on the comparison of magnetic spectroscopic measurements of glutamate and gamma-aminobutyric acid + in the medial prefrontal cortex of women with major depression. Journal of affective disorders. 2024-01-20. PMID:38244791. |
the role played by medial prefrontal cortex (mpfc) glutamate (glu) and gamma-aminobutyric acid (gaba) in the pathophysiology and the treatment of major depression (md) is increasingly recognized. |
2024-01-20 |
2024-01-23 |
Not clear |
| Kim H Tran, Jessica Luki, Sarah Hanstock, Christopher C Hanstock, Peter Seres, Katherine Aitchison, Tami Shandro, Jean-Michel Le Melled. The impact of matching for reproductive status on the comparison of magnetic spectroscopic measurements of glutamate and gamma-aminobutyric acid + in the medial prefrontal cortex of women with major depression. Journal of affective disorders. 2024-01-20. PMID:38244791. |
the impact of matching for reproductive status on the comparison of magnetic spectroscopic measurements of glutamate and gamma-aminobutyric acid + in the medial prefrontal cortex of women with major depression. |
2024-01-20 |
2024-01-23 |
Not clear |
| Timur Liwinski, Undine E Lang, Annette B Brühl, Else Schneide. Exploring the Therapeutic Potential of Gamma-Aminobutyric Acid in Stress and Depressive Disorders through the Gut-Brain Axis. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137351. |
research conducted on individuals with depression reveals that major depressive disorders (mdds) coincide with diminished levels of the inhibitory neurotransmitter γ-aminobutyric acid (gaba) in the brain, as well as modifications in the subunit composition of the primary receptors (gaba |
2023-12-23 |
2023-12-25 |
Not clear |
| Sumanpreet Kaur, Preeti Sharma, Melinda J Mayer, Saskia Neuert, Arjan Narbad, Sukhraj Kau. Beneficial effects of GABA-producing potential probiotic Limosilactobacillus fermentum L18 of human origin on intestinal permeability and human gut microbiota. Microbial cell factories. vol 22. issue 1. 2023-12-13. PMID:38087304. |
gamma-aminobutyric acid (gaba) is a non-protein amino acid with neuroinhibitory, antidiabetic, and antihypertensive properties and is used as a drug for treating anxiety and depression. |
2023-12-13 |
2023-12-17 |
human |
| Xunjia Qian, Xinyi Zhao, Lulu Yu, Yujian Yin, Xiao-Dan Zhang, Liyun Wang, Jun-Xu Li, Qing Zhu, Jia-Lie Lu. Current status of GABA receptor subtypes in analgesia. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 168. 2023-11-07. PMID:37935070. |
gaba plays crucial roles in the regulation of synaptic transmission, the promotion of neuronal development and relaxation, and the prevention of insomnia and depression. |
2023-11-07 |
2023-11-20 |
Not clear |
| Hao Zhang, Mingqi Qiao, Dongmei Gao, Jieqiong Wang, Chunyan Sun, Ya Sun, Yang Zhang, Huayuan Liu, Zhen Zhang, Mingzhou Ga. Shuyu capsule alleviates premenstrual depression via allopregnanolone metabolic pathway targeting GABA (A) receptors δ subunit in the hippocampus. Asian journal of psychiatry. vol 90. 2023-10-28. PMID:37898099. |
shuyu capsule alleviates premenstrual depression via allopregnanolone metabolic pathway targeting gaba (a) receptors δ subunit in the hippocampus. |
2023-10-28 |
2023-11-08 |
rat |
| Sagar V Parikh, Scott T Aaronson, Sanjay J Mathew, Gustavo Alva, Charles DeBattista, Stephen Kanes, Robert Lasser, Amy Bullock, Mona Kotecha, JungAh Jung, Fiona Forrestal, Jeff Jonas, Theresa Vera, Bridgette Leclair, James Dohert. Efficacy and safety of zuranolone co-initiated with an antidepressant in adults with major depressive disorder: results from the phase 3 CORAL study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-10-24. PMID:37875578. |
zuranolone is a neuroactive steroid and positive allosteric modulator of synaptic and extrasynaptic γ-aminobutyric acid (gaba) type a receptors approved as an oral, once-daily, 14-day treatment course in adults with postpartum depression and under investigation in adults with mdd. |
2023-10-24 |
2023-11-08 |
Not clear |
| Yun Fei Feng, Yin Yong Zhou, Kai Ming Dua. The Role of Extrasynaptic GABA Receptors in Postpartum Depression. Molecular neurobiology. 2023-08-23. PMID:37612480. |
the role of extrasynaptic gaba receptors in postpartum depression. |
2023-08-23 |
2023-09-07 |
Not clear |
| Yun Fei Feng, Yin Yong Zhou, Kai Ming Dua. The Role of Extrasynaptic GABA Receptors in Postpartum Depression. Molecular neurobiology. 2023-08-23. PMID:37612480. |
recent studies have shown that gaba receptors, especially extrasynaptic receptors, are closely associated with postpartum depression. |
2023-08-23 |
2023-09-07 |
Not clear |
| Yun Fei Feng, Yin Yong Zhou, Kai Ming Dua. The Role of Extrasynaptic GABA Receptors in Postpartum Depression. Molecular neurobiology. 2023-08-23. PMID:37612480. |
in this review, we focus on the function of gaba receptors, especially extrasynaptic gaba receptors, and their association with postpartum depression. |
2023-08-23 |
2023-09-07 |
Not clear |
| Kim H Tran, Jessica Luki, Sarah Hanstock, Christopher C Hanstock, Peter Seres, Katherine Aitchison, Jean-Michel Le Melled. Decreased GABA+ ratios referenced to creatine and phosphocreatine in the left dorsolateral prefrontal cortex of females of reproductive age with major depression. Journal of psychiatry & neuroscience : JPN. vol 48. issue 4. 2023-08-22. PMID:37607825. |
given that most female patients with mdd are of reproductive age, we sought to assess in vivo baseline gaba levels in the left dlpfc among unmedicated females of reproductive age with depression. |
2023-08-22 |
2023-09-07 |
Not clear |
| Takahito Uchida, Yuki Sugiura, Eiji Sugiyama, Rae Maeda, Kenji F Tanaka, Makoto Suematsu, Masaru Mimura, Hiroyuki Uchid. Metabolites for monitoring symptoms and predicting remission in patients with depression who received electroconvulsive therapy: a pilot study. Scientific reports. vol 13. issue 1. 2023-08-14. PMID:37580528. |
furthermore, we investigated the relationship between metabolite levels and depression severity across seven measurement timepoints along with one correlation analysis and found that amino acids, including gaba and tryptophan catabolites, were significantly correlated with the severity of depression. |
2023-08-14 |
2023-09-07 |
Not clear |
| Nazanin Hatami Bavarsad, Shokufeh Bagheri, Masoumeh Kourosh-Arami, Alireza Komak. Aromatherapy for the brain: Lavender's healing effect on epilepsy, depression, anxiety, migraine, and Alzheimer's disease: A review article. Heliyon. vol 9. issue 8. 2023-08-09. PMID:37554839. |
this plant exerts its healing effect on many diseases, such as anxiety and depression through an inhibitory effect on gaba. |
2023-08-09 |
2023-08-16 |
Not clear |
| Bernhard Luscher, Jamie L Maguire, Uwe Rudolph, Etienne Sibill. GABA Trends in pharmacological sciences. 2023-08-05. PMID:37543478. |
gaba in the past 20 years, our understanding of the pathophysiology of depression has evolved from a focus on an imbalance of monoaminergic neurotransmitters to a multifactorial picture including an improved understanding of the role of glutamatergic excitatory and gabaergic inhibitory neurotransmission. |
2023-08-05 |
2023-08-14 |
Not clear |
| Konlarat Phirom-On, Anuchida Po-Ngern, Somchai Jaikhan, Sasiwan Sirichon, Sukanda Vichitphan, Kanit Vichitphan, Jirawan Apiraksakor. Understanding the hindrance factor of bacterial proliferation and γ-aminobutyric acid-producing capability of nondairy strains of Lactiplantibacillus plantarum in milk fermentation. Scientific reports. vol 13. issue 1. 2023-07-15. PMID:37454227. |
γ-aminobutyric-acid (gaba) is a mental health-supporting substance that helps release anxiety and depression and improves memory. |
2023-07-15 |
2023-08-14 |
Not clear |
| Sella Takei, Hiroshi Kinoshita, Mostofa Jamal, Mitsuru Kumihashi, Tadayoshi Yamashita, Etsuko Tanaka, Sachiko Kawahara, Hiroko Abe, Kunihiko Tsutsui, Shoji Kimur. Case report: Fatal poisoning caused by additive effects of two barbiturates. Frontiers in pharmacology. vol 14. 2023-06-09. PMID:37292155. |
as both pentobarbital and phenobarbital act on gamma-aminobutyric acid (gaba) receptors, central nervous system activity was suppressed, causing respiratory depression. |
2023-06-09 |
2023-08-14 |
Not clear |
| Milica Radosavljevic, Dubravka Svob Strac, Jasna Jancic, Janko Samardzi. The Role of Pharmacogenetics in Personalizing the Antidepressant and Anxiolytic Therapy. Genes. vol 14. issue 5. 2023-05-27. PMID:37239455. |
pharmacogenetic research on depression and anxiety has focused on genetic polymorphisms affecting metabolizing cytochrome p450 (cyp) and uridine 5'-diphospho-glucuronosyltransferase (ugt) enzymes, p-glycoprotein atp-binding cassette (abc) transporters, and monoamine and γ-aminobutyric acid (gaba) metabolic enzymes, transporters, and receptors. |
2023-05-27 |
2023-08-14 |
Not clear |
| Weiming Sun, Xizhen Kang, Xiangli Dong, Zijian Zeng, Qing Zou, Meixiang Su, Ke Zhang, Guanxiu Liu, Guohua Y. Effect of transcranial direct current stimulation on postpartum depression: A study protocol for a randomized controlled trial. Frontiers in psychology. vol 14. 2023-03-06. PMID:36874857. |
it may also ease depression indirectly by promoting the production and release of the neurotransmitter gaba. |
2023-03-06 |
2023-08-14 |
Not clear |
| Kim Ros. Psychobiotics: Are they the future intervention for managing depression and anxiety? A literature review. Explore (New York, N.Y.). 2023-03-03. PMID:36868988. |
overall, the current evidence suggests that 1) specific strains of probiotics can reduce depressive symptoms and anxiety; 2) symptoms may be reduced through one or more possible mechanisms of action, including impact on the synthesis of neurotransmitters such as serotonin and gaba, modulation of inflammatory cytokines, or enhancing stress responses through effects on stress hormones and the hpa axis; and 3) while psychobiotics may offer therapeutic benefits to manage depression and anxiety, further research, particularly human studies, is needed to better characterize their mode of action and understand optimal dosing in the context of nutritional interventions. |
2023-03-03 |
2023-08-14 |
human |
| Muhammad Asim, Huajie Wang, Abdul Wari. Altered neurotransmission in stress-induced depressive disorders: The underlying role of the amygdala in depression. Neuropeptides. vol 98. 2023-01-26. PMID:36702033. |
in this literature review, we overviewed depression and the key role of gamma-aminobutyric acid (gaba) and glutamate neurotransmission in depression. |
2023-01-26 |
2023-08-14 |
Not clear |