| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Krnjević, Y Z Xu, L Zhan. Anoxic block of GABAergic IPSPs. Neurochemical research. vol 16. issue 3. 1992-03-10. PMID:1780029. |
iontophoretic applications of gaba or baclofen indicated no major depression of responses during anoxia. |
1992-03-10 |
2023-08-11 |
rat |
| A Roy, J Dejong, T Ferrar. CSF GABA in depressed patients and normal controls. Psychological medicine. vol 21. issue 3. 1991-12-11. PMID:1719577. |
the inhibitory neurotransmitter gamma-aminobutyric acid (gaba) has been implicated in the pathophysiology of depression. |
1991-12-11 |
2023-08-11 |
Not clear |
| G B Baker, J T Wong, J M Yeung, R T Coutt. Effects of the antidepressant phenelzine on brain levels of gamma-aminobutyric acid (GABA). Journal of affective disorders. vol 21. issue 3. 1991-08-14. PMID:1648582. |
the possible importance of gaba in the etiology and pharmacotherapy of depression and panic disorder is discussed. |
1991-08-14 |
2023-08-11 |
rat |
| K Sakatani, M Chesler, A Z Hassa. GABAA receptors modulate axonal conduction in dorsal columns of neonatal rat spinal cord. Brain research. vol 542. issue 2. 1991-06-19. PMID:1851457. |
since gaba causes a pronounced depression of excitability in preparations of unmyelinated axons, and myelination is incomplete in the neonatal rat, we tested whether gaba can modulate conduction in the dorsal columns of 10-17-day-old rats. |
1991-06-19 |
2023-08-11 |
rat |
| H el-Beheiry, E Pui. Effects of hypomagnesia on transmitter actions in neocortical slices. British journal of pharmacology. vol 101. issue 4. 1991-05-23. PMID:1982229. |
the dose-dependent depression of gaba actions by low extracellular [mg2+] additionally provides a plausible mechanism that may contribute to the neuronal hyperexcitability that is observed during conditions of hypomagnesemia. |
1991-05-23 |
2023-08-11 |
Not clear |
| C G Benson, M C Chase, S J Potashne. Decreased release of D-aspartate in the guinea pig spinal cord after lesions of the red nucleus. Journal of neurochemistry. vol 56. issue 4. 1991-04-15. PMID:2002335. |
because other evidence suggests that rubrospinal neurons are probably not gabaergic, the depression of [14c]gaba release probably reflects changes in the activity of spinal interneurons following the loss of rubrospinal input. |
1991-04-15 |
2023-08-11 |
Not clear |
| A S Basile, N L Ostrowski, S H Gammal, E A Jones, P Skolnic. The involvement of the benzodiazepine receptor in hepatic encephalopathy: evidence for the presence of a benzodiazepine receptor ligand. Advances in biochemical psychopharmacology. vol 46. 1991-04-01. PMID:1963266. |
the involvement of gabaergic systems in the pathogenesis of he was supported by electrophysiologic studies of single purkinje neurons from rabbits with he which demonstrated the hypersensitivity of these neurons to depression by gaba and bz receptor agonists. |
1991-04-01 |
2023-08-11 |
human |
| P K Sher, S H. GABA accumulating neurons are relatively resistant to chronic hypoxia in vitro: an autoradiographic study. Brain research bulletin. vol 25. issue 5. 1991-04-01. PMID:2289158. |
these observations suggest that certain gabaergic cortical neurons are relatively more resistant to chronic hypoxia than the general neuronal population and that depression of overall neuronal gaba uptake may be associated with enhanced glial gaba uptake. |
1991-04-01 |
2023-08-11 |
mouse |
| E Puil, H el-Beheir. Anaesthetic suppression of transmitter actions in neocortex. British journal of pharmacology. vol 101. issue 1. 1991-03-15. PMID:1980837. |
the order of depression was acetylcholine greater than glutamate or nmda much greater than gaba. |
1991-03-15 |
2023-08-11 |
Not clear |
| J E Melton, J A Neubauer, N H Edelma. GABA antagonism reverses hypoxic respiratory depression in the cat. Journal of applied physiology (Bethesda, Md. : 1985). vol 69. issue 4. 1991-02-01. PMID:2124585. |
gaba antagonism reverses hypoxic respiratory depression in the cat. |
1991-02-01 |
2023-08-11 |
cat |
| J E Melton, J A Neubauer, N H Edelma. GABA antagonism reverses hypoxic respiratory depression in the cat. Journal of applied physiology (Bethesda, Md. : 1985). vol 69. issue 4. 1991-02-01. PMID:2124585. |
we assessed the role of gamma-aminobutyric acid (gaba) as a potential causative agent of hypoxic respiratory depression by monitoring the response of the phrenic neurogram to systemic infusion of the gaba antagonist bicuculline (0.01 mg.kg-1.min-1) under control conditions and during isocapnic brain hypoxia produced by co inhalation in separate groups of anesthetized, glomectomized, vagotomized, paralyzed, and ventilated cats with blood pressure held constant. |
1991-02-01 |
2023-08-11 |
cat |
| J E Melton, J A Neubauer, N H Edelma. GABA antagonism reverses hypoxic respiratory depression in the cat. Journal of applied physiology (Bethesda, Md. : 1985). vol 69. issue 4. 1991-02-01. PMID:2124585. |
these results suggest that although gaba has only a modest role in determining the output of the control phrenic neurogram, a significant portion of the phrenic depression that occurs during hypoxia can be attributed to inhibition of respiratory neurons by gaba. |
1991-02-01 |
2023-08-11 |
cat |
| P Monteleone, M Maj, M Iovino, L Steard. GABA, depression and the mechanism of action of antidepressant drugs: a neuroendocrine approach. Journal of affective disorders. vol 20. issue 1. 1991-01-09. PMID:2174069. |
gaba, depression and the mechanism of action of antidepressant drugs: a neuroendocrine approach. |
1991-01-09 |
2023-08-11 |
human |
| F Petty, G L Kramer, D Dunnam, A J Rus. Plasma GABA in mood disorders. Psychopharmacology bulletin. vol 26. issue 2. 1990-12-14. PMID:2236451. |
levels of plasma gaba were similar among diagnostic groups (primary unipolar depression, bipolar depression, mania, and secondary depression). |
1990-12-14 |
2023-08-11 |
Not clear |
| F Petty, G L Kramer, D Dunnam, A J Rus. Plasma GABA in mood disorders. Psychopharmacology bulletin. vol 26. issue 2. 1990-12-14. PMID:2236451. |
no differences in plasma gaba were found in patients classified according to family history, nor were any correlations found between plasma gaba levels and severity of depression as determined by the 17-item hamilton rating scale for depression. |
1990-12-14 |
2023-08-11 |
Not clear |
| I V Batueva, E I Suderevskai. [The effect of glycine and gamma-aminobutyric acid on the excitatory postsynaptic potentials of the spinal motor neurons in the lamprey in the presence of antagonists]. Neirofiziologiia = Neurophysiology. vol 22. issue 3. 1990-10-18. PMID:2169034. |
all these antagonists diminished the depression of monosynaptic epsps which were elicited by both amino acids (glycine and gaba). |
1990-10-18 |
2023-08-11 |
Not clear |
| A P Ferk. The interaction between ethanol and cysteine on the central depressant effects of ethanol in mice. Pharmacology, biochemistry, and behavior. vol 36. issue 3. 1990-09-05. PMID:2377662. |
the interaction of ethanol with gamma-aminobutyric acid (gaba) and isethionic acid, a metabolite of taurine, was also investigated on ethanol-induced central nervous system depression as measured by loss of the righting reflex experiments. |
1990-09-05 |
2023-08-11 |
mouse |
| G Y Mazda, A Nistri, L Sivilott. The effect of GABA on the frog optic tectum is sensitive to ammonium and to penicillin. European journal of pharmacology. vol 179. issue 1-2. 1990-08-13. PMID:2163848. |
in 50% cl- media the depression of gaba and glycine responses by nh+4 was more intense. |
1990-08-13 |
2023-08-11 |
Not clear |
| K G Lloyd, P Pichat, B Scatton, B Zivkovic, P L Morselli, G Bartholin. The psychopharmacology of GABA synapses: update 1989. Journal of neural transmission. Supplementum. vol 29. 1990-08-01. PMID:2162909. |
the antidepressant profile of gaba agonists in animal models for depression has been extended. |
1990-08-01 |
2023-08-11 |
Not clear |
| K G Lloyd, P Pichat, B Scatton, B Zivkovic, P L Morselli, G Bartholin. The psychopharmacology of GABA synapses: update 1989. Journal of neural transmission. Supplementum. vol 29. 1990-08-01. PMID:2162909. |
the role of gaba receptors in the mechanism of action of antidepressants has been further delineated, with a parallelism occurring between the behavioral and biochemical response to antidepressant drug treatment in different animal models of depression. |
1990-08-01 |
2023-08-11 |
Not clear |