| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ke Ma, Hongxiu Zhang, Guohui Wei, Zhenfei Dong, Haijun Zhao, Xiaochun Han, Xiaobin Song, Huiling Zhang, Xin Zong, Zulqarnain Baloch, Shijun Wan. Identification of key genes, pathways, and miRNA/mRNA regulatory networks of CUMS-induced depression in nucleus accumbens by integrated bioinformatics analysis. Neuropsychiatric disease and treatment. vol 15. 2020-10-01. PMID:30936699. |
stress-induced dysfunction in the subtype of neuronal cells and the change of synaptic plasticity and structural plasticity of nucleus accumbens (nac) are implicated in depression symptomology. |
2020-10-01 |
2023-08-13 |
Not clear |
| Anders C Meidahl, Dariusz Orlowski, Jens C H Sørensen, Carsten R Bjarka. The Retrograde Connections and Anatomical Segregation of the Göttingen Minipig Nucleus Accumbens. Frontiers in neuroanatomy. vol 10. 2020-09-30. PMID:27994542. |
nucleus accumbens (nacc) has been implicated in several psychiatric disorders such as treatment resistant depression (trd), and obsessive-compulsive disorder (ocd), and has been an ongoing experimental target for deep brain stimulation (dbs) in both rats and humans. |
2020-09-30 |
2023-08-13 |
human |
| Bettina Drisaldi, Luca Colnaghi, Amir Levine, YanYou Huang, Anna M Snyder, Daniel J Metzger, Martin Theis, Denise B Kandel, Eric R Kandel, Luana Fiorit. Cytoplasmic Polyadenylation Element Binding Proteins CPEB1 and CPEB3 Regulate the Translation of FosB and Are Required for Maintaining Addiction-Like Behaviors Induced by Cocaine. Frontiers in cellular neuroscience. vol 14. 2020-09-28. PMID:32742260. |
supporting these behavioral results, we also found a difference between wt and dn-cpeb1-3 mice in the cocaine-induced synaptic depression in the core of the nucleus accumbens (nac). |
2020-09-28 |
2023-08-13 |
mouse |
| Ke Ma, Hongxiu Zhang, Shiyuan Wang, Huaxin Wang, Yuan Wang, Juhai Liu, Xiaobin Song, Zhenfei Dong, Xiaochun Han, Yanan Zhang, Honglei Li, Abdul Rahaman, Shijun Wang, Zulqarnain Baloc. The molecular mechanism underlying GABAergic dysfunction in nucleus accumbens of depression-like behaviours in mice. Journal of cellular and molecular medicine. vol 23. issue 10. 2020-09-02. PMID:31430030. |
recent evidence has shown that stress-induced gabaergic dysfunction in the nucleus accumbens (nac) contributed to the pathophysiology of depression. |
2020-09-02 |
2023-08-13 |
mouse |
| Weichen Song, Yifeng Shen, Yanhua Zhang, Sufang Peng, Ran Zhang, Ailing Ning, Huafang Li, Xia Li, Guan Ning Lin, Shunying Y. Expression alteration of microRNAs in Nucleus Accumbens is associated with chronic stress and antidepressant treatment in rats. BMC medical informatics and decision making. vol 19. issue Suppl 6. 2020-08-04. PMID:31856805. |
nucleus accumbens (nac) is a vital brain region for the process of reward and stress, whereas microrna plays a crucial role in depression pathology. |
2020-08-04 |
2023-08-13 |
rat |
| S Amiri, M Arbabi, K Kazemi, M Parvaresh-Rizi, M M Mirbagher. Resting-State Functional Connectivity in Popular Targets for Deep Brain Stimulation in the Treatment of Major Depression: An Application of a Graph Theory. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2019. 2020-06-03. PMID:31946827. |
we examined the functional connectivity of subcallosal cingulate gyrus (scg), nucleus accumbens (nac), and ventral caudate (vca), the main target areas for the treatment of major depression disorder (mdd), using deep brain stimulation (dbs). |
2020-06-03 |
2023-08-13 |
human |
| Serhat Baydin, Kaan Yagmurlu, Necmettin Tanriover, Abuzer Gungor, Albert L Rhoto. Microsurgical and Fiber Tract Anatomy of the Nucleus Accumbens. Operative neurosurgery (Hagerstown, Md.). vol 12. issue 3. 2019-11-20. PMID:29506114. |
the nucleus accumbens (nac) has been a target for deep brain stimulation (dbs) in the treatment of depression and obsessive-compulsive disorder (ocd). |
2019-11-20 |
2023-08-13 |
Not clear |
| Yawei Si, Zhenhua Song, Xiaoyan Sun, Jin-Hui Wan. microRNA and mRNA profiles in nucleus accumbens underlying depression versus resilience in response to chronic stress. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 177. issue 6. 2019-09-16. PMID:30105773. |
microrna and mrna profiles in nucleus accumbens underlying depression versus resilience in response to chronic stress. |
2019-09-16 |
2023-08-13 |
mouse |
| Yawei Si, Zhenhua Song, Xiaoyan Sun, Jin-Hui Wan. microRNA and mRNA profiles in nucleus accumbens underlying depression versus resilience in response to chronic stress. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 177. issue 6. 2019-09-16. PMID:30105773. |
high-throughput sequencing was used to analyze mrna and mirna quantity in the nucleus accumbens (nac) harvested from the mice in the groups of control, cums-induced depression (cums-mdd), and cums-resistance to identify molecular profiles of cums-mdd versus cums-resilience. |
2019-09-16 |
2023-08-13 |
mouse |
| Volker M Tronnier, Dirk Rasche, Veronika Thorns, Daniel Alvarez-Fischer, Thomas F Münte, Bartosz Zurowsk. Massive weight loss following deep brain stimulation of the nucleus accumbens in a depressed woman. Neurocase. vol 24. issue 1. 2019-09-09. PMID:29388475. |
a woman with treatment-resistant depression as well as severe obesity was selected for dbs of the nucleus accumbens (nacc) bilaterally with depression being the primary and obesity being the secondary target of treatment. |
2019-09-09 |
2023-08-13 |
Not clear |
| Kengo Furuse, Wataru Ukai, Eri Hashimoto, Hanako Hashiguchi, Yoshiyasu Kigawa, Takao Ishii, Masaya Tayama, Kenta Deriha, Masaki Shiraishi, Chiaki Kawanish. Antidepressant activities of escitalopram and blonanserin on prenatal and adolescent combined stress-induced depression model: Possible role of neurotrophic mechanism change in serum and nucleus accumbens. Journal of affective disorders. vol 247. 2019-05-08. PMID:30658246. |
antidepressant activities of escitalopram and blonanserin on prenatal and adolescent combined stress-induced depression model: possible role of neurotrophic mechanism change in serum and nucleus accumbens. |
2019-05-08 |
2023-08-13 |
Not clear |
| Lisanne M Jenkins, Kristy A Skerrett, Sophie R DelDonno, Víctor G Patrón, Kortni K Meyers, Scott Peltier, Jon-Kar Zubieta, Scott A Langenecker, Monica N Starkma. Individuals with more severe depression fail to sustain nucleus accumbens activity to preferred music over time. Psychiatry research. Neuroimaging. vol 275. 2019-04-01. PMID:29555382. |
individuals with more severe depression fail to sustain nucleus accumbens activity to preferred music over time. |
2019-04-01 |
2023-08-13 |
Not clear |
| Léa Décarie-Spain, Sandeep Sharma, Cécile Hryhorczuk, Victor Issa-Garcia, Philip A Barker, Nathalie Arbour, Thierry Alquier, Stephanie Fulto. Nucleus accumbens inflammation mediates anxiodepressive behavior and compulsive sucrose seeking elicited by saturated dietary fat. Molecular metabolism. vol 10. 2019-03-15. PMID:29454579. |
obesity arising from excessive intake of high-fat food provokes anxiodepressive behavior and elicits molecular adaptations in the nucleus accumbens (nac), a region well-implicated in the hedonic deficits associated with depression and in the control of food-motivated behavior. |
2019-03-15 |
2023-08-13 |
Not clear |
| Xiao-Bo Wu, Peng-Bo Jing, Zhi-Jun Zhang, De-Li Cao, Ming-Hui Gao, Bao-Chun Jiang, Yong-Jing Ga. Chemokine receptor CCR2 contributes to neuropathic pain and the associated depression via increasing NR2B-mediated currents in both D1 and D2 dopamine receptor-containing medium spiny neurons in the nucleus accumbens shell. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 11. 2019-03-11. PMID:29993042. |
the nucleus accumbens (nac) is an important area in mediating pain sensation and depression. |
2019-03-11 |
2023-08-13 |
mouse |
| Seonil Kim, Jiayi Shou, Sinedu Abera, Edward B Zif. Sucrose withdrawal induces depression and anxiety-like behavior by Kir2.1 upregulation in the nucleus accumbens. Neuropharmacology. vol 130. 2019-02-11. PMID:29191750. |
sucrose withdrawal induces depression and anxiety-like behavior by kir2.1 upregulation in the nucleus accumbens. |
2019-02-11 |
2023-08-13 |
Not clear |
| Zachary S Lorsch, Yong-Hwee Eddie Loh, Immanuel Purushothaman, Deena M Walker, Eric M Parise, Marine Salery, Michael E Cahill, Georgia E Hodes, Madeline L Pfau, Hope Kronman, Peter J Hamilton, Orna Issler, Benoit Labonté, Ann E Symonds, Matthew Zucker, Tie Yuan Zhang, Michael J Meaney, Scott J Russo, Li Shen, Rosemary C Bagot, Eric J Nestle. Estrogen receptor α drives pro-resilient transcription in mouse models of depression. Nature communications. vol 9. issue 1. 2018-12-11. PMID:29549264. |
we identify estrogen receptor α (erα) as the top regulator of pro-resilient transcriptional changes in the nucleus accumbens (nac), a key brain reward region implicated in depression. |
2018-12-11 |
2023-08-13 |
mouse |
| Jihye Choi, Hyun Cho, Jin-Young Kim, Dong Jin Jung, Kook Jin Ahn, Hang-Bong Kang, Jung-Seok Choi, Ji-Won Chun, Dai-Jin Ki. Structural alterations in the prefrontal cortex mediate the relationship between Internet gaming disorder and depressed mood. Scientific reports. vol 7. issue 1. 2018-09-04. PMID:28455501. |
striatal volumetric analysis detected a significant reduction in the right nucleus accumbens (nacc) in the igd group and its association with lifetime usage of gaming and depression. |
2018-09-04 |
2023-08-13 |
Not clear |
| Jessie Muir, Zachary S Lorsch, Charu Ramakrishnan, Karl Deisseroth, Eric J Nestler, Erin S Calipari, Rosemary C Bago. In Vivo Fiber Photometry Reveals Signature of Future Stress Susceptibility in Nucleus Accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 2. 2018-07-30. PMID:28589967. |
stress-induced alterations in the activity of reward-related brain regions, such as the nucleus accumbens (nac), are linked to the pathophysiology of depression. |
2018-07-30 |
2023-08-13 |
mouse |
| Mitra Heshmati, Hossein Aleyasin, Caroline Menard, Daniel J Christoffel, Meghan E Flanigan, Madeline L Pfau, Georgia E Hodes, Ashley E Lepack, Lucy K Bicks, Aki Takahashi, Ramesh Chandra, Gustavo Turecki, Mary Kay Lobo, Ian Maze, Sam A Golden, Scott J Russ. Cell-type-specific role for nucleus accumbens neuroligin-2 in depression and stress susceptibility. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 5. 2018-07-25. PMID:29339486. |
cell-type-specific role for nucleus accumbens neuroligin-2 in depression and stress susceptibility. |
2018-07-25 |
2023-08-13 |
mouse |
| Mitra Heshmati, Hossein Aleyasin, Caroline Menard, Daniel J Christoffel, Meghan E Flanigan, Madeline L Pfau, Georgia E Hodes, Ashley E Lepack, Lucy K Bicks, Aki Takahashi, Ramesh Chandra, Gustavo Turecki, Mary Kay Lobo, Ian Maze, Sam A Golden, Scott J Russ. Cell-type-specific role for nucleus accumbens neuroligin-2 in depression and stress susceptibility. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 5. 2018-07-25. PMID:29339486. |
behavioral coping strategies are critical for active resilience to stress and depression; here we describe a role for neuroligin-2 (nlgn-2) in the nucleus accumbens (nac). |
2018-07-25 |
2023-08-13 |
mouse |