| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Willard J Costain, Joseph S Tauskela, Ingrid Rasquinha, Tanya Comas, Melissa Hewitt, Vincent Marleau, Evelyn C So. Pharmacological characterization of emerging synthetic cannabinoids in HEK293T cells and hippocampal neurons. European journal of pharmacology. vol 786. 2017-03-10. PMID:27260125. |
assessment of agonist-stimulated depression of ca(2+) transients was also used to confirm the efficacy of five escs (xlr-11, jwh-250, ab-pinaca, 5f-pb-22, and mam-2201) in cultured primary hippocampal neurons. |
2017-03-10 |
2023-08-13 |
human |
| Ming-Ming Tang, Wen-Juan Lin, Yu-Qin Pan, Xi-Ting Guan, Ying-Cong L. Hippocampal neurogenesis dysfunction linked to depressive-like behaviors in a neuroinflammation induced model of depression. Physiology & behavior. vol 161. 2017-03-06. PMID:27106565. |
hippocampal neurogenesis dysfunction linked to depressive-like behaviors in a neuroinflammation induced model of depression. |
2017-03-06 |
2023-08-13 |
rat |
| Ming-Ming Tang, Wen-Juan Lin, Yu-Qin Pan, Xi-Ting Guan, Ying-Cong L. Hippocampal neurogenesis dysfunction linked to depressive-like behaviors in a neuroinflammation induced model of depression. Physiology & behavior. vol 161. 2017-03-06. PMID:27106565. |
since several neuroinflammation-associated conditions have been reported to impair neurogenesis, in this study, we further investigated whether the neuroinflammation induced depression would be associated with hippocampal neurogenesis dysfunction. |
2017-03-06 |
2023-08-13 |
rat |
| Ming-Ming Tang, Wen-Juan Lin, Yu-Qin Pan, Xi-Ting Guan, Ying-Cong L. Hippocampal neurogenesis dysfunction linked to depressive-like behaviors in a neuroinflammation induced model of depression. Physiology & behavior. vol 161. 2017-03-06. PMID:27106565. |
these findings provide the first evidence that hippocampal neurogenesis dysfunction is correlated with neuroinflammation-induced depression, which suggests that hippocampal neurogenesis might be one of biological mechanisms underlying depression induced by neruoinflammation. |
2017-03-06 |
2023-08-13 |
rat |
| Bodo C Melni. Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity. Acta dermato-venereologica. vol 97. issue 2. 2017-02-28. PMID:27671426. |
furthermore, apoptosis may be the underlying and unifying mechanism of the adverse effects of isotretinoin on neural crest cells (teratogenicity), hippocampal neurones (depression), epidermal keratinocytes and mucosa cells (mucocutaneous side-effects), hair follicle cells (telogen effluvium), intestinal epithelial cells (inflammatory bowel disease), skeletal muscle cells (myalgia and release of creatine kinase), and hepatocytes (release of transaminases and very low-density lipoproteins). |
2017-02-28 |
2023-08-13 |
Not clear |
| Taisuke Joko, Shinsuke Washizuka, Daimei Sasayama, Shin Inuzuka, Tomomi Ogihara, Takehiko Yasaki, Tetsuya Hagiwara, Nobuhiro Sugiyama, Tohru Takahashi, Tomoki Kaneko, Tokiji Hanihara, Naoji Aman. Patterns of hippocampal atrophy differ among Alzheimer's disease, amnestic mild cognitive impairment, and late-life depression. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. vol 16. issue 6. 2017-02-14. PMID:26756596. |
patterns of hippocampal atrophy differ among alzheimer's disease, amnestic mild cognitive impairment, and late-life depression. |
2017-02-14 |
2023-08-13 |
Not clear |
| Ashok Jangra, Chandra Shaker Sriram, Shubham Dwivedi, Satendra Singh Gurjar, Md Iftikar Hussain, Probodh Borah, Mangala Lahka. Sodium Phenylbutyrate and Edaravone Abrogate Chronic Restraint Stress-Induced Behavioral Deficits: Implication of Oxido-Nitrosative, Endoplasmic Reticulum Stress Cascade, and Neuroinflammation. Cellular and molecular neurobiology. vol 37. issue 1. 2017-02-13. PMID:26886752. |
chronic stress exposure can produce deleterious effects on the hippocampus (hc) which eventually leads to cognitive impairment and depression. |
2017-02-13 |
2023-08-13 |
mouse |
| Chunye Wang, Jianyou Guo, Rongjuan Gu. Effect of XingPiJieYu decoction on spatial learning and memory and cAMP-PKA-CREB-BDNF pathway in rat model of depression through chronic unpredictable stress. BMC complementary and alternative medicine. vol 17. issue 1. 2017-02-13. PMID:28118829. |
recently, some animal tests have indicated that the cyclic adenosine monophosphate (camp)-protein kinase a (pka)-camp response element-binding protein (creb)-brain derived neurotrophic factor (bdnf) signaling pathway in hippocampus is closely related to depression and the pathogenesis of cognitive function impairments. |
2017-02-13 |
2023-08-13 |
rat |
| A D Kruchinina, S S Gamzin, M T Tengi. Effects of Single Administration of Bupropion on Carboxypeptidase E Activity in Structures of Rat Brain. Bulletin of experimental biology and medicine. vol 161. issue 6. 2017-02-09. PMID:27783296. |
activation of the enzyme in the medulla oblongata, hypothalamus, and hippocampus observed in 72 h after bupropion administration probably leads to enhanced synthesis and secretion of regulatory peptides (reduced during stress and depression) and stimulation of neurogenesis. |
2017-02-09 |
2023-08-13 |
rat |
| Carlos Borges Filho, Cristiano Ricardo Jesse, Franciele Donato, Lucian Del Fabbro, Marcelo Gomes de Gomes, André Tiago Rossito Goes, Leandro Cattelan Souza, Silvana Peterini Boeir. Chrysin promotes attenuation of depressive-like behavior and hippocampal dysfunction resulting from olfactory bulbectomy in mice. Chemico-biological interactions. vol 260. 2017-01-31. PMID:27818124. |
in this work, we investigated the action of chrysin treatment (5 or 20 mg/kg) for 14 days in the depressant-like behavior and in the hippocampal dysfunction induced by olfactory bulbectomy (ob), an animal model of agitated depression. |
2017-01-31 |
2023-08-13 |
mouse |
| Chang-Hong Wang, Jing-Yang Gu, Xiao-Li Zhang, Jiao Dong, Jun Yang, Ying-Li Zhang, Qiu-Fen Ning, Xiao-Wen Shan, Yan L. Venlafaxine ameliorates the depression-like behaviors and hippocampal S100B expression in a rat depression model. Behavioral and brain functions : BBF. vol 12. issue 1. 2017-01-27. PMID:27931233. |
venlafaxine ameliorates the depression-like behaviors and hippocampal s100b expression in a rat depression model. |
2017-01-27 |
2023-08-13 |
rat |
| Eti Patrich, Yael Piontkewitz, Asher Peretz, Ina Weiner, Bernard Attal. Maturation- and sex-sensitive depression of hippocampal excitatory transmission in a rat schizophrenia model. Brain, behavior, and immunity. vol 51. 2017-01-10. PMID:26327125. |
maturation- and sex-sensitive depression of hippocampal excitatory transmission in a rat schizophrenia model. |
2017-01-10 |
2023-08-13 |
rat |
| Eti Patrich, Yael Piontkewitz, Asher Peretz, Ina Weiner, Bernard Attal. Maturation- and sex-sensitive depression of hippocampal excitatory transmission in a rat schizophrenia model. Brain, behavior, and immunity. vol 51. 2017-01-10. PMID:26327125. |
depression of hippocampal excitatory transmission appeared at juvenile age in male offspring of the poly i:c group, while it expressed with a delay in female, manifesting at adulthood. |
2017-01-10 |
2023-08-13 |
rat |
| Jiook Cha, Tsafrir Greenberg, Inkyung Song, Helen Blair Simpson, Jonathan Posner, Lilianne R Mujica-Parod. Abnormal hippocampal structure and function in clinical anxiety and comorbid depression. Hippocampus. vol 26. issue 5. 2017-01-06. PMID:26743454. |
abnormal hippocampal structure and function in clinical anxiety and comorbid depression. |
2017-01-06 |
2023-08-13 |
Not clear |
| Jiook Cha, Tsafrir Greenberg, Inkyung Song, Helen Blair Simpson, Jonathan Posner, Lilianne R Mujica-Parod. Abnormal hippocampal structure and function in clinical anxiety and comorbid depression. Hippocampus. vol 26. issue 5. 2017-01-06. PMID:26743454. |
collectively, our findings show a strong association between changes in hippocampal microstructure and threat processing, which together may present a common neural pathway to comorbidity of anxiety and depression. |
2017-01-06 |
2023-08-13 |
Not clear |
| Lauren Osborne, Makena Clive, Mary Kimmel, Fiona Gispen, Jerry Guintivano, Tori Brown, Olivia Cox, Jennifer Judy, Samantha Meilman, Aviva Braier, Matthias W Beckmann, Johannes Kornhuber, Peter A Fasching, Fernando Goes, Jennifer L Payne, Elisabeth B Binder, Zachary Kaminsk. Replication of Epigenetic Postpartum Depression Biomarkers and Variation with Hormone Levels. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 6. 2017-01-05. PMID:26503311. |
dna methylation variation at hp1bp3 and ttc9b is modified by estrogen exposure in the rodent hippocampus and was previously shown to be prospectively predictive of postpartum depression (ppd) when modeled in antenatal blood. |
2017-01-05 |
2023-08-13 |
Not clear |
| María Llorens-Martín, Jerónimo Jurado-Arjona, Marta Bolós, Noemí Pallas-Bazarra, Jesús Ávil. Forced swimming sabotages the morphological and synaptic maturation of newborn granule neurons and triggers a unique pro-inflammatory milieu in the hippocampus. Brain, behavior, and immunity. vol 53. 2017-01-03. PMID:26724574. |
given that the hippocampus is one of the most affected areas in these disorders, we used a model of acute stress (the porsolt test) to evaluate the consequences of forced swimming on two crucial events related to the pathophysiology of major depression: the functional maturation of newborn granule neurons; and the hippocampal inflammatory milieu. |
2017-01-03 |
2023-08-13 |
Not clear |
| Jiro Kasahara, Hiroto Uchida, Kenta Tezuka, Nanae Ok. Postischemic Anhedonia Associated with Neurodegenerative Changes in the Hippocampal Dentate Gyrus of Rats. Neural plasticity. vol 2016. 2016-12-30. PMID:27057366. |
overall, our study suggests new insights for the mechanistic correlation between poststroke depression and the delayed neurodegenerative changes in the hippocampal dentate gyrus with effective use of antidepressants on them. |
2016-12-30 |
2023-08-13 |
rat |
| Pernille Bøttger, Simon Glerup, Bodil Gesslein, Nina B Illarionova, Toke J Isaksen, Anders Heuck, Bettina H Clausen, Ernst-Martin Füchtbauer, Jan B Gramsbergen, Eli Gunnarson, Anita Aperia, Martin Lauritzen, Kate L Lambertsen, Poul Nissen, Karin Lykke-Hartman. Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model. Scientific reports. vol 6. 2016-12-19. PMID:26911348. |
in vitro studies showed impaired glutamate uptake in hippocampal mixed astrocyte-neuron cultures from α2(g301r/g301r) e17 embryonic mice, and moreover, induction of cortical spreading depression (csd) resulted in reduced recovery in α2(+/g301r) male mice. |
2016-12-19 |
2023-08-13 |
mouse |
| Peter T Nelson, Gregory A Jicha, Wang-Xia Wang, Eseosa Ighodaro, Sergey Artiushin, Colin G Nichols, David W Fard. ABCC9/SUR2 in the brain: Implications for hippocampal sclerosis of aging and a potential therapeutic target. Ageing research reviews. vol 24. issue Pt B. 2016-12-13. PMID:26226329. |
more common brain disorders linked to abcc9 gene variants include hippocampal sclerosis of aging (hs-aging), sleep disorders, and depression. |
2016-12-13 |
2023-08-13 |
human |