| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jikun Wang, Xudong Zhao, Ming H. Is BDNF biological link between depression and type 2 diabetes mellitus? Medical hypotheses. vol 79. issue 2. 2012-11-30. PMID:22626954. |
studies examining the components of the bdnf system in patients with t2dm and depression may provide new understanding into the link between depression and t2dm. |
2012-11-30 |
2023-08-12 |
Not clear |
| B J Hasselbalch, U Knorr, B Bennike, S G Hasselbalch, M H Greisen Søndergaard, L Vedel Kessin. Decreased levels of brain-derived neurotrophic factor in the remitted state of unipolar depressive disorder. Acta psychiatrica Scandinavica. vol 126. issue 3. 2012-11-16. PMID:22292883. |
decreased levels of peripheral brain-derived neurotrophic factor (bdnf) have been associated with depression. |
2012-11-16 |
2023-08-12 |
Not clear |
| Kayoko Fukuhara, Kozo Ishikawa, Seiko Yasuda, Yusuke Kishishita, Hae-Kyu Kim, Takahiro Kakeda, Misa Yamamoto, Takafumi Norii, Toshizo Ishikaw. Intracerebroventricular 4-methylcatechol (4-MC) ameliorates chronic pain associated with depression-like behavior via induction of brain-derived neurotrophic factor (BDNF). Cellular and molecular neurobiology. vol 32. issue 6. 2012-11-13. PMID:22198556. |
therefore, enhancement of bdnf may be a new treatment strategy for chronic pain associated with depression. |
2012-11-13 |
2023-08-12 |
rat |
| Anilkumar Pillai, Davide Bruno, Antero S Sarreal, Raymundo T Hernando, Leslie A Saint-Louis, Jay Nierenberg, Stephen D Ginsberg, Nunzio Pomara, Pankaj D Mehta, Henrik Zetterberg, Kaj Blennow, Peter F Buckle. Plasma BDNF levels vary in relation to body weight in females. PloS one. vol 7. issue 7. 2012-11-13. PMID:22768299. |
brain derived neurotrophic factor (bdnf) has been implicated in the pathophysiology of depression as well as neuropsychiatric and neurodegenerative disorders. |
2012-11-13 |
2023-08-12 |
human |
| J De Vry, J Prickaerts, M Jetten, M Hulst, H W M Steinbusch, D L A van den Hove, T Schuurman, F J van der Staa. Recurrent long-lasting tethering reduces BDNF protein levels in the dorsal hippocampus and frontal cortex in pigs. Hormones and behavior. vol 62. issue 1. 2012-11-06. PMID:22584108. |
brain-derived neurotrophic factor (bdnf) signaling has been implicated in the onset of depression and in antidepressant efficacy, although the exact role of this neurotrophin in the pathophysiology of depression remains to be elucidated. |
2012-11-06 |
2023-08-12 |
Not clear |
| Yu Pei, Alicia K Smith, Yongjun Wang, Yanli Pan, Jian Yang, Qi Chen, Weigang Pan, Feng Bao, Lisha Zhao, Changle Tie, Yizheng Wang, Jian Wang, Wenfeng Zhen, Jinxia Zhou, Xin M. The brain-derived neurotrophic-factor (BDNF) val66met polymorphism is associated with geriatric depression: a meta-analysis. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 159B. issue 5. 2012-10-11. PMID:22610920. |
the brain-derived neurotrophic-factor (bdnf) val66met polymorphism is associated with geriatric depression: a meta-analysis. |
2012-10-11 |
2023-08-12 |
Not clear |
| Yu Pei, Alicia K Smith, Yongjun Wang, Yanli Pan, Jian Yang, Qi Chen, Weigang Pan, Feng Bao, Lisha Zhao, Changle Tie, Yizheng Wang, Jian Wang, Wenfeng Zhen, Jinxia Zhou, Xin M. The brain-derived neurotrophic-factor (BDNF) val66met polymorphism is associated with geriatric depression: a meta-analysis. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 159B. issue 5. 2012-10-11. PMID:22610920. |
depression has been associated with reduced expression of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2012-10-11 |
2023-08-12 |
Not clear |
| Yu Pei, Alicia K Smith, Yongjun Wang, Yanli Pan, Jian Yang, Qi Chen, Weigang Pan, Feng Bao, Lisha Zhao, Changle Tie, Yizheng Wang, Jian Wang, Wenfeng Zhen, Jinxia Zhou, Xin M. The brain-derived neurotrophic-factor (BDNF) val66met polymorphism is associated with geriatric depression: a meta-analysis. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 159B. issue 5. 2012-10-11. PMID:22610920. |
genetic association studies of the bdnf val66met polymorphism (rs6265) in geriatric depression have produced inconsistent results. |
2012-10-11 |
2023-08-12 |
Not clear |
| Yu Pei, Alicia K Smith, Yongjun Wang, Yanli Pan, Jian Yang, Qi Chen, Weigang Pan, Feng Bao, Lisha Zhao, Changle Tie, Yizheng Wang, Jian Wang, Wenfeng Zhen, Jinxia Zhou, Xin M. The brain-derived neurotrophic-factor (BDNF) val66met polymorphism is associated with geriatric depression: a meta-analysis. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 159B. issue 5. 2012-10-11. PMID:22610920. |
a meta-analysis of studies was conducted to compare the frequency of the bdnf val66met variant between cases with geriatric depression and age-matched controls. |
2012-10-11 |
2023-08-12 |
Not clear |
| Yu Pei, Alicia K Smith, Yongjun Wang, Yanli Pan, Jian Yang, Qi Chen, Weigang Pan, Feng Bao, Lisha Zhao, Changle Tie, Yizheng Wang, Jian Wang, Wenfeng Zhen, Jinxia Zhou, Xin M. The brain-derived neurotrophic-factor (BDNF) val66met polymorphism is associated with geriatric depression: a meta-analysis. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 159B. issue 5. 2012-10-11. PMID:22610920. |
our findings suggest the bdnf met allele may confer increased risk for depression as individual age. |
2012-10-11 |
2023-08-12 |
Not clear |
| Jae-Min Kim, Robert Stewart, Kyung-Yeol Bae, Sung-Wan Kim, Hee-Ju Kang, Il-Seon Shin, Joon-Tae Kim, Man-Seok Park, Myung-Kyu Kim, Sung-Woo Park, Young-Hoon Kim, Jong-Keun Kim, Ki-Hyun Cho, Jin-Sang Yoo. Serotonergic and BDNF genes and risk of depression after stroke. Journal of affective disorders. vol 136. issue 3. 2012-10-09. PMID:22014446. |
serotonergic and bdnf genes and risk of depression after stroke. |
2012-10-09 |
2023-08-12 |
Not clear |
| Jae-Min Kim, Robert Stewart, Kyung-Yeol Bae, Sung-Wan Kim, Hee-Ju Kang, Il-Seon Shin, Joon-Tae Kim, Man-Seok Park, Myung-Kyu Kim, Sung-Woo Park, Young-Hoon Kim, Jong-Keun Kim, Ki-Hyun Cho, Jin-Sang Yoo. Serotonergic and BDNF genes and risk of depression after stroke. Journal of affective disorders. vol 136. issue 3. 2012-10-09. PMID:22014446. |
polymorphisms of serotonin transporter (5-htt) and brain-derived neurotrophic factor (bdnf) have been investigated as candidate genes for post-stroke depression (psd). |
2012-10-09 |
2023-08-12 |
Not clear |
| Laura Gedge, Ashley Beaudoin, Lauren Lazowski, Regina du Toit, Ruzica Jokic, Roumen Mile. Effects of electroconvulsive therapy and repetitive transcranial magnetic stimulation on serum brain-derived neurotrophic factor levels in patients with depression. Frontiers in psychiatry. vol 3. 2012-10-02. PMID:22375129. |
brain-derived neurotrophic factor (bdnf) levels are decreased in individuals with depression and increase following antidepressant treatment. |
2012-10-02 |
2023-08-12 |
Not clear |
| YeeWen Candace Wu, Rachel A Hill, Maren Klug, Maarten van den Buus. Sex-specific and region-specific changes in BDNF-TrkB signalling in the hippocampus of 5-HT1A receptor and BDNF single and double mutant mice. Brain research. vol 1452. 2012-09-14. PMID:22464183. |
brain-derived neurotrophic factor (bdnf) and serotonin 5-ht1a receptors are implicated in the pathophysiology of depression and the mechanism of action of antidepressant drugs. |
2012-09-14 |
2023-08-12 |
mouse |
| YeeWen Candace Wu, Rachel A Hill, Maren Klug, Maarten van den Buus. Sex-specific and region-specific changes in BDNF-TrkB signalling in the hippocampus of 5-HT1A receptor and BDNF single and double mutant mice. Brain research. vol 1452. 2012-09-14. PMID:22464183. |
given the greater vulnerability of women to develop depression and the role of the vhp in stress responses and anxiety-related behaviours, our results may shed more light on sex differences in depression and other psychiatric disorders with bdnf and 5-ht1a receptor dysfunction. |
2012-09-14 |
2023-08-12 |
mouse |
| Rongju Sun, Nanxin Li, Tanshi L. VEGF regulates antidepressant effects of lamotrigine. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 22. issue 6. 2012-09-10. PMID:22033393. |
our previous studies have demonstrated that brain derived neurotrophic factor (bdnf) signaling plays an important role in regulating its behavioral actions in several rodent models of depression. |
2012-09-10 |
2023-08-12 |
Not clear |
| Gabriele Masi, Paola Brovedan. The hippocampus, neurotrophic factors and depression: possible implications for the pharmacotherapy of depression. CNS drugs. vol 25. issue 11. 2012-09-05. PMID:22054117. |
as bdnf is repressed by stress, epigenetic regulation of the bdnf gene may play an important role in depression. |
2012-09-05 |
2023-08-12 |
Not clear |
| Mauricio Schüler Nin, Luis A Martinez, Fabio Pibiri, Marianela Nelson, Graziano Pinn. Neurosteroids reduce social isolation-induced behavioral deficits: a proposed link with neurosteroid-mediated upregulation of BDNF expression. Frontiers in endocrinology. vol 2. 2012-08-23. PMID:22649384. |
the pharmacological action of selective serotonin reuptake inhibitor antidepressants may include a normalization of the decreased brain levels of the brain-derived neurotrophic factor (bdnf) and of neurosteroids such as the progesterone metabolite allopregnanolone, which are decreased in patients with depression and posttraumatic stress disorders (ptsd). |
2012-08-23 |
2023-08-12 |
mouse |
| Fani L Neto, Gisela Borges, Sonia Torres-Sanchez, Juan A Mico, Esther Berrocos. Neurotrophins role in depression neurobiology: a review of basic and clinical evidence. Current neuropharmacology. vol 9. issue 4. 2012-08-23. PMID:22654714. |
both basic and clinical evidence indicates that depression is associated with several structural and neurochemical changes where the levels of neurotrophins, particularly of brain-derived neurotrophic factor (bdnf), are altered. |
2012-08-23 |
2023-08-12 |
Not clear |
| Alessandra Berry, Veronica Bellisario, Sara Capoccia, Paola Tirassa, Arianna Calza, Enrico Alleva, Francesca Cirull. Social deprivation stress is a triggering factor for the emergence of anxiety- and depression-like behaviours and leads to reduced brain BDNF levels in C57BL/6J mice. Psychoneuroendocrinology. vol 37. issue 6. 2012-08-16. PMID:21974975. |
neurotrophins, such as brain-derived neurotrophic factor (bdnf), have been identified as neuroendocrine effectors involved in the response to stress and in the neurobehavioural changes associated with depression. |
2012-08-16 |
2023-08-12 |
mouse |