| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Naoko Takebayashi, Hitoshi Maeshima, Hajime Baba, Yoshiyuki Nakano, Emi Satomura, Yohei Kita, Yuki Namekawa, Hiroshi Nomoto, Toshihito Suzuki, Heii Ara. Duration of last depressive episode may influence serum BDNF levels in remitted patients with major depression. Depression and anxiety. vol 29. issue 9. 2013-01-29. PMID:22447660. |
previous studies indicate that serum bdnf levels were lower in patients with depression and increased after treatment with antidepressants. |
2013-01-29 |
2023-08-12 |
Not clear |
| Naoko Takebayashi, Hitoshi Maeshima, Hajime Baba, Yoshiyuki Nakano, Emi Satomura, Yohei Kita, Yuki Namekawa, Hiroshi Nomoto, Toshihito Suzuki, Heii Ara. Duration of last depressive episode may influence serum BDNF levels in remitted patients with major depression. Depression and anxiety. vol 29. issue 9. 2013-01-29. PMID:22447660. |
however, results of studies on serum bdnf levels in remitted patients with depression have been inconsistent. |
2013-01-29 |
2023-08-12 |
Not clear |
| Naoko Takebayashi, Hitoshi Maeshima, Hajime Baba, Yoshiyuki Nakano, Emi Satomura, Yohei Kita, Yuki Namekawa, Hiroshi Nomoto, Toshihito Suzuki, Heii Ara. Duration of last depressive episode may influence serum BDNF levels in remitted patients with major depression. Depression and anxiety. vol 29. issue 9. 2013-01-29. PMID:22447660. |
the purpose of the present study was to determine which factors influence the alteration of serum bdnf levels in depression in the remitted state. |
2013-01-29 |
2023-08-12 |
Not clear |
| T Laudes, S Meis, T Munsch, V Lessman. Impaired transmission at corticothalamic excitatory inputs and intrathalamic GABAergic synapses in the ventrobasal thalamus of heterozygous BDNF knockout mice. Neuroscience. vol 222. 2013-01-24. PMID:22796079. |
for miniature inhibitory postsynaptic currents (mipscs) recorded in tc neurons, both, frequency and amplitude showed a significant reduction in knock-out animals, concurrent with a prolonged decay time constant, whereas paired-pulse depression and synaptic fatigue of inhibitory synapses were not significantly different between wt and bdnf(+/-) mice. |
2013-01-24 |
2023-08-12 |
mouse |
| Lin Zhang, Tianyuan Xu, Shuang Wang, Lanqing Yu, Dexiang Liu, Renzhi Zhan, Shu Yan Y. Curcumin produces antidepressant effects via activating MAPK/ERK-dependent brain-derived neurotrophic factor expression in the amygdala of mice. Behavioural brain research. vol 235. issue 1. 2013-01-23. PMID:22820234. |
the present study attempts to explore the mechanisms underlying the antidepressant-like action of curcumin by measuring the contents of brain derived neurotrophic factor (bdnf) in the amygdala of animal model of depression. |
2013-01-23 |
2023-08-12 |
mouse |
| Amine Bahi, Jean-Luc Dreye. Hippocampus-specific deletion of tissue plasminogen activator "tPA" in adult mice impairs depression- and anxiety-like behaviors. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 22. issue 9. 2013-01-17. PMID:22377193. |
in this study we further investigate the role of tissue plasminogen activator (tpa), a serine protease involved in pro-bdnf cleavage to bdnf, in depression and anxiety-like behaviors in adult mice. |
2013-01-17 |
2023-08-12 |
mouse |
| Betina Elfving, Henriette N Buttenschøn, Leslie Foldager, Pia H P Poulsen, Johan H Andersen, Matias B Grynderup, Åse M Hansen, Henrik A Kolstad, Linda Kaerlev, Sigurd Mikkelsen, Jane F Thomsen, Anders D Børglum, Gregers Wegener, Ole Mor. Depression, the Val66Met polymorphism, age, and gender influence the serum BDNF level. Journal of psychiatric research. vol 46. issue 9. 2013-01-09. PMID:22682508. |
brain-derived neurotrophic factor (bdnf) has been suggested as a candidate gene for depression and numerous studies have investigated the possible association between genetic variants within bdnf and depression. |
2013-01-09 |
2023-08-12 |
human |
| Betina Elfving, Henriette N Buttenschøn, Leslie Foldager, Pia H P Poulsen, Johan H Andersen, Matias B Grynderup, Åse M Hansen, Henrik A Kolstad, Linda Kaerlev, Sigurd Mikkelsen, Jane F Thomsen, Anders D Børglum, Gregers Wegener, Ole Mor. Depression, the Val66Met polymorphism, age, and gender influence the serum BDNF level. Journal of psychiatric research. vol 46. issue 9. 2013-01-09. PMID:22682508. |
clinical studies have investigated the serum bdnf levels in individuals with depression. |
2013-01-09 |
2023-08-12 |
human |
| Betina Elfving, Henriette N Buttenschøn, Leslie Foldager, Pia H P Poulsen, Johan H Andersen, Matias B Grynderup, Åse M Hansen, Henrik A Kolstad, Linda Kaerlev, Sigurd Mikkelsen, Jane F Thomsen, Anders D Børglum, Gregers Wegener, Ole Mor. Depression, the Val66Met polymorphism, age, and gender influence the serum BDNF level. Journal of psychiatric research. vol 46. issue 9. 2013-01-09. PMID:22682508. |
the purpose of the present study was therefore to perform an investigation of bdnf using 162 individuals with depression and 289 healthy individuals. |
2013-01-09 |
2023-08-12 |
human |
| Betina Elfving, Henriette N Buttenschøn, Leslie Foldager, Pia H P Poulsen, Johan H Andersen, Matias B Grynderup, Åse M Hansen, Henrik A Kolstad, Linda Kaerlev, Sigurd Mikkelsen, Jane F Thomsen, Anders D Børglum, Gregers Wegener, Ole Mor. Depression, the Val66Met polymorphism, age, and gender influence the serum BDNF level. Journal of psychiatric research. vol 46. issue 9. 2013-01-09. PMID:22682508. |
in conclusion, our data demonstrate that other factors than a diagnosis of depression influence the serum bdnf level and the importance of these factors should be emphasized comparing different studies. |
2013-01-09 |
2023-08-12 |
human |
| Norio Yasui-Furukori, Shoko Tsuchimine, Taku Nakagami, Akira Fujii, Yasushi Sato, Tetsu Tomita, Kaori Yoshizawa, Yoshimasa Inoue, Sunao Kanek. Association between plasma paroxetine concentration and changes in plasma brain‐derived neurotrophic factor levels in patients with major depressive disorder. Human psychopharmacology. vol 26. issue 3. 2012-12-13. PMID:21638327. |
recent studies have implicated brain‐derived neurotrophic factor (bdnf) in the pathophysiology of depression and in the activities of antidepressant drugs. |
2012-12-13 |
2023-08-12 |
Not clear |
| Norio Yasui-Furukori, Shoko Tsuchimine, Taku Nakagami, Akira Fujii, Yasushi Sato, Tetsu Tomita, Kaori Yoshizawa, Yoshimasa Inoue, Sunao Kanek. Association between plasma paroxetine concentration and changes in plasma brain‐derived neurotrophic factor levels in patients with major depressive disorder. Human psychopharmacology. vol 26. issue 3. 2012-12-13. PMID:21638327. |
we assessed plasma bdnf levels and paroxetine concentrations in 45 patients with major depression who were being treated with paroxetine. |
2012-12-13 |
2023-08-12 |
Not clear |
| Juan Gibert Rahol. Somatic drugs for psychiatric diseases: aspirin or simvastatin for depression? Current neuropharmacology. vol 10. issue 2. 2012-12-12. PMID:23204984. |
although scientists are still a long way from understanding its true aetiology, the neurobiological concept of depression has evolved from receptor regulation disorder, to a neurodegenerative disorder with a hippocampal volume decrease with the controversial reduction in neurotrophins such as bdnf, to current hypotheses that consider depression to be an inflammatory and neuroprogressive process. |
2012-12-12 |
2023-08-12 |
Not clear |
| H Stuke, R Hellweg, F Bermpoh. [The development of depression: the role of brain-derived neurotrophic factor]. Der Nervenarzt. vol 83. issue 7. 2012-12-10. PMID:21947218. |
the studies show a reduction of bdnf secretion in stressful situations, a decreased blood concentration in depression and a normalization of bdnf by successful antidepressant therapy. |
2012-12-10 |
2023-08-12 |
Not clear |
| H Stuke, R Hellweg, F Bermpoh. [The development of depression: the role of brain-derived neurotrophic factor]. Der Nervenarzt. vol 83. issue 7. 2012-12-10. PMID:21947218. |
the question of whether the ascertained changes of bdnf levels are causally involved in the pathophysiology of depression or whether they are just an epiphenomenal result of depression-induced stress is still under debate. |
2012-12-10 |
2023-08-12 |
Not clear |
| Hiroshi Kunugi, Hiroaki Hori, Tadahiro Numakawa, Miho Ot. [The hypothalamic-pituitary-adrenal axis and depressive disorder: recent progress]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 32. issue 4. 2012-12-10. PMID:23012888. |
brain-derived neurotrophic factor (bdnf) has also been implicated in depression. |
2012-12-10 |
2023-08-12 |
Not clear |
| G Paslakis, W F Blum, M Deuschl. Intranasal insulin-like growth factor I (IGF-I) as a plausible future treatment of depression. Medical hypotheses. vol 79. issue 2. 2012-11-30. PMID:22626951. |
an enormous body of evidence links the regulation of specific neurotrophic proteins, like the brain-derived neurotrophic factor (bdnf), to depression and it may be assumed that the behavioral effects of antidepressants require functional bdnf signaling in the brain. |
2012-11-30 |
2023-08-12 |
human |
| Jikun Wang, Xudong Zhao, Ming H. Is BDNF biological link between depression and type 2 diabetes mellitus? Medical hypotheses. vol 79. issue 2. 2012-11-30. PMID:22626954. |
is bdnf biological link between depression and type 2 diabetes mellitus? |
2012-11-30 |
2023-08-12 |
Not clear |
| Jikun Wang, Xudong Zhao, Ming H. Is BDNF biological link between depression and type 2 diabetes mellitus? Medical hypotheses. vol 79. issue 2. 2012-11-30. PMID:22626954. |
biological and clinical studies have repeatedly shown that bdnf is important in the pathogenesis of depression and t2dm. |
2012-11-30 |
2023-08-12 |
Not clear |
| Jikun Wang, Xudong Zhao, Ming H. Is BDNF biological link between depression and type 2 diabetes mellitus? Medical hypotheses. vol 79. issue 2. 2012-11-30. PMID:22626954. |
therefore, we propose that bdnf may play an important role linking depression and t2dm. |
2012-11-30 |
2023-08-12 |
Not clear |