| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ana Maria Brailean, Ernst H W Koster, Kristof Hoorelbeke, Rudi De Raed. Attentional modulation by reward and punishment cues in relation to depressive symptoms. Journal of behavior therapy and experimental psychiatry. vol 45. issue 3. 2015-01-29. PMID:24727341. |
the current study aimed to examine the interplay between these risk factors for depression by examining the development of attentional bias toward reward and loss signals in dysphoric participants (individuals with elevated levels of depressive symptoms). |
2015-01-29 |
2023-08-13 |
human |
| Johann du Hoffmann, Saleem M Nicol. Dopamine invigorates reward seeking by promoting cue-evoked excitation in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 43. 2015-01-23. PMID:25339748. |
approach to reward is a fundamental adaptive behavior, disruption of which is a core symptom of addiction and depression. |
2015-01-23 |
2023-08-13 |
rat |
| David H Root, Carlos A Mejias-Aponte, Shiliang Zhang, Hui-Ling Wang, Alexander F Hoffman, Carl R Lupica, Marisela Morale. Single rodent mesohabenular axons release glutamate and GABA. Nature neuroscience. vol 17. issue 11. 2015-01-12. PMID:25242304. |
the lateral habenula (lhb) is involved in reward, aversion, addiction and depression through descending interactions with several brain structures, including the ventral tegmental area (vta). |
2015-01-12 |
2023-08-13 |
mouse |
| Randy P Auerbach, Roee Admon, Diego A Pizzagall. Adolescent depression: stress and reward dysfunction. Harvard review of psychiatry. vol 22. issue 3. 2014-12-23. PMID:24704785. |
adolescent depression: stress and reward dysfunction. |
2014-12-23 |
2023-08-13 |
human |
| Randy P Auerbach, Roee Admon, Diego A Pizzagall. Adolescent depression: stress and reward dysfunction. Harvard review of psychiatry. vol 22. issue 3. 2014-12-23. PMID:24704785. |
evaluate the relationship between reward processes, stress, and depression. |
2014-12-23 |
2023-08-13 |
human |
| Randy P Auerbach, Roee Admon, Diego A Pizzagall. Adolescent depression: stress and reward dysfunction. Harvard review of psychiatry. vol 22. issue 3. 2014-12-23. PMID:24704785. |
in this review, we provide a selective overview of current animal and human research investigating the relationship among reward processes, stress, and depression. |
2014-12-23 |
2023-08-13 |
human |
| Randy P Auerbach, Roee Admon, Diego A Pizzagall. Adolescent depression: stress and reward dysfunction. Harvard review of psychiatry. vol 22. issue 3. 2014-12-23. PMID:24704785. |
three separate, but related, etiological models examine the differential roles that stress may play in relation to reward dysfunction and adolescent depression. |
2014-12-23 |
2023-08-13 |
human |
| Randy P Auerbach, Roee Admon, Diego A Pizzagall. Adolescent depression: stress and reward dysfunction. Harvard review of psychiatry. vol 22. issue 3. 2014-12-23. PMID:24704785. |
first, the reward mediation model suggests that both acute and chronic stress contribute to reward deficits, which, in turn, potentiate depressive symptoms or increase the risk for depression. |
2014-12-23 |
2023-08-13 |
human |
| Randy P Auerbach, Roee Admon, Diego A Pizzagall. Adolescent depression: stress and reward dysfunction. Harvard review of psychiatry. vol 22. issue 3. 2014-12-23. PMID:24704785. |
third, consistent with a diathesis-stress model, the interaction between stress and premorbid reward dysfunction may contribute to the onset of depression. |
2014-12-23 |
2023-08-13 |
human |
| Randy P Auerbach, Roee Admon, Diego A Pizzagall. Adolescent depression: stress and reward dysfunction. Harvard review of psychiatry. vol 22. issue 3. 2014-12-23. PMID:24704785. |
to highlight the translational potential of these insights, a hypothetical case study is provided as a means of demonstrating the importance of targeting reward dysfunction in both assessment and treatment of adolescent depression. |
2014-12-23 |
2023-08-13 |
human |
| Thomas E Schlaepfer, Bettina H Bewernick, Sarah Kayser, Rene Hurlemann, Volker A Coene. Deep brain stimulation of the human reward system for major depression--rationale, outcomes and outlook. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 6. 2014-12-15. PMID:24513970. |
deep brain stimulation of the human reward system for major depression--rationale, outcomes and outlook. |
2014-12-15 |
2023-08-12 |
human |
| Thomas E Schlaepfer, Bettina H Bewernick, Sarah Kayser, Rene Hurlemann, Volker A Coene. Deep brain stimulation of the human reward system for major depression--rationale, outcomes and outlook. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 6. 2014-12-15. PMID:24513970. |
this overview summarizes research on the mechanisms of brain networks with respect to psychiatric diseases and--as a novelty--extrapolates to the role of the reward system in dbs for patients with treatment-resistant depression. |
2014-12-15 |
2023-08-12 |
human |
| Thomas E Schlaepfer, Bettina H Bewernick, Sarah Kayser, Rene Hurlemann, Volker A Coene. Deep brain stimulation of the human reward system for major depression--rationale, outcomes and outlook. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 6. 2014-12-15. PMID:24513970. |
on the scientific side, the reward system has an important yet clearly under-recognized role in both neurobiology and treatment of depression. |
2014-12-15 |
2023-08-12 |
human |
| Małgorzata Frankowska, Joanna Jastrzębska, Ewa Nowak, Magdalena Białko, Edmund Przegaliński, Małgorzata Fili. The effects of N-acetylcysteine on cocaine reward and seeking behaviors in a rat model of depression. Behavioural brain research. vol 266. 2014-12-12. PMID:24613240. |
the effects of n-acetylcysteine on cocaine reward and seeking behaviors in a rat model of depression. |
2014-12-12 |
2023-08-12 |
rat |
| Małgorzata Frankowska, Joanna Jastrzębska, Ewa Nowak, Magdalena Białko, Edmund Przegaliński, Małgorzata Fili. The effects of N-acetylcysteine on cocaine reward and seeking behaviors in a rat model of depression. Behavioural brain research. vol 266. 2014-12-12. PMID:24613240. |
nac (25-100mg/kg) given acutely or repeatedly did not alter the co-occurrence of cocaine reward and depression but effectively reduced the cocaine-seeking behavior observed in both phenotypes. |
2014-12-12 |
2023-08-12 |
rat |
| A J Robison, Vincent Vialou, Hao-Sheng Sun, Benoit Labonte, Sam A Golden, Caroline Dias, Gustavo Turecki, Carol Tamminga, Scott Russo, Michelle Mazei-Robison, Eric J Nestle. Fluoxetine epigenetically alters the CaMKIIα promoter in nucleus accumbens to regulate ΔFosB binding and antidepressant effects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 5. 2014-12-01. PMID:24240473. |
recent work in addiction models demonstrates that the transcription factor Δfosb and protein kinase calmodulin-dependent protein kinase ii (camkii) are co-regulated in nucleus accumbens (nac), a brain reward region implicated in both addiction and depression models including social defeat. |
2014-12-01 |
2023-08-12 |
mouse |
| Tal Gonen, Haggai Sharon, Godfrey Pearlson, Talma Hendle. Moods as ups and downs of the motivation pendulum: revisiting reinforcement sensitivity theory (RST) in bipolar disorder. Frontiers in behavioral neuroscience. vol 8. 2014-11-18. PMID:25404902. |
corresponding to current neurobehavioral theories in psychiatry, this theory links abnormal motivational drives to abnormal behavior; viewing depression and mania as two abnormal extremes of reward driven processes leading to either under or over approach tendencies, respectively. |
2014-11-18 |
2023-08-13 |
Not clear |
| Geoffrey B C Hall, Andrea M B Milne, Glenda M Macquee. An fMRI study of reward circuitry in patients with minimal or extensive history of major depression. European archives of psychiatry and clinical neuroscience. vol 264. issue 3. 2014-11-04. PMID:23990079. |
an fmri study of reward circuitry in patients with minimal or extensive history of major depression. |
2014-11-04 |
2023-08-12 |
human |
| Geoffrey B C Hall, Andrea M B Milne, Glenda M Macquee. An fMRI study of reward circuitry in patients with minimal or extensive history of major depression. European archives of psychiatry and clinical neuroscience. vol 264. issue 3. 2014-11-04. PMID:23990079. |
in addition, areas such as the nucleus accumbens, anterior cingulate and ventral prefrontal cortices were activated greatest by controls during reward processing, less by patients early in the course of illness and least by patients with highly recurrent illness-suggesting that these areas are sensitive to the impact of disease burden and repeated episodes of depression. |
2014-11-04 |
2023-08-12 |
human |
| Geoffrey B C Hall, Andrea M B Milne, Glenda M Macquee. An fMRI study of reward circuitry in patients with minimal or extensive history of major depression. European archives of psychiatry and clinical neuroscience. vol 264. issue 3. 2014-11-04. PMID:23990079. |
reward processing in people with depression may be associated with diminished signaling of incentive salience, a reduction in the formation of reward-related associations and heightened sensitivities for negatively valenced stimuli, all of which could contribute to symptoms of depression. |
2014-11-04 |
2023-08-12 |
human |