| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bettina Ubl, Christine Kuehner, Peter Kirsch, Michaela Ruttorf, Carsten Diener, Herta Flo. Altered neural reward and loss processing and prediction error signalling in depression. Social cognitive and affective neuroscience. vol 10. issue 8. 2016-02-26. PMID:25567763. |
dysfunctional processing of reward and punishment may play an important role in depression. |
2016-02-26 |
2023-08-13 |
Not clear |
| Scott M Thompson, Angy J Kallarackal, Mark D Kvarta, Adam M Van Dyke, Tara A LeGates, Xiang Ca. An excitatory synapse hypothesis of depression. Trends in neurosciences. vol 38. issue 5. 2016-01-19. PMID:25887240. |
here, we propose an excitatory synapse hypothesis of depression in which chronic stress and genetic susceptibility cause changes in the strength of subsets of glutamatergic synapses at multiple locations, including the prefrontal cortex (pfc), hippocampus, and nucleus accumbens (nac), leading to a dysfunction of corticomesolimbic reward circuitry that underlies many of the symptoms of depression. |
2016-01-19 |
2023-08-13 |
Not clear |
| Emily A Ferenczi, Kelly A Zalocusky, Conor Liston, Logan Grosenick, Melissa R Warden, Debha Amatya, Kiefer Katovich, Hershel Mehta, Brian Patenaude, Charu Ramakrishnan, Paul Kalanithi, Amit Etkin, Brian Knutson, Gary H Glover, Karl Deisserot. Prefrontal cortical regulation of brainwide circuit dynamics and reward-related behavior. Science (New York, N.Y.). vol 351. issue 6268. 2016-01-19. PMID:26722001. |
motivation for reward drives adaptive behaviors, whereas impairment of reward perception and experience (anhedonia) can contribute to psychiatric diseases, including depression and schizophrenia. |
2016-01-19 |
2023-08-13 |
rat |
| Nils Opel, Ronny Redlich, Dominik Grotegerd, Katharina Dohm, Cordula Haupenthal, Walter Heindel, Harald Kugel, Volker Arolt, Udo Dannlowsk. Enhanced neural responsiveness to reward associated with obesity in the absence of food-related stimuli. Human brain mapping. vol 36. issue 6. 2016-01-15. PMID:25704752. |
given the crucial role of rewarding effects in the development of obesity and the ongoing discussion on overlapping neurobiological traits of obesity and psychiatric disorders such as depression and substance-related disorders, this study aimed to investigate the possibility of altered reward processing in obese subjects to occur in the absence of food-related stimuli during a monetary reward condition. |
2016-01-15 |
2023-08-13 |
human |
| J Straub, P L Plener, N Sproeber, L Sprenger, M G Koelch, G Groen, B Able. Neural correlates of successful psychotherapy of depression in adolescents. Journal of affective disorders. vol 183. 2016-01-12. PMID:26025370. |
given the concordance of the ventral striatum, amygdala, hippocampus and the subgenual anterior cingulate cortex (sgacc) as correlates of depression and their involvement in reward processing, we used functional magnetic resonance imaging (fmri) during performance of a monetary reward task in an intervention versus waitlist-control design to investigate the clinical and neural effects of cognitive behavioral group therapy (cbt-g). |
2016-01-12 |
2023-08-13 |
Not clear |
| Gisela Grecksch, Axel Becke. Alterations of reward mechanisms in bulbectomised rats. Behavioural brain research. vol 286. 2016-01-04. PMID:25771711. |
we investigated the relationship between depression and reward mechanisms using a validated animal model for depressive-like behaviour, the olfactory bulbectomy in rats. |
2016-01-04 |
2023-08-13 |
rat |
| Gisela Grecksch, Axel Becke. Alterations of reward mechanisms in bulbectomised rats. Behavioural brain research. vol 286. 2016-01-04. PMID:25771711. |
these results suggest that the reward mechanisms may be altered in this animal model as a common phenomenon associated with depression. |
2016-01-04 |
2023-08-13 |
rat |
| Jessica Franzen, Kerstin Brinkman. Blunted cardiovascular reactivity in dysphoria during reward and punishment anticipation. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. vol 95. issue 3. 2015-11-16. PMID:25462217. |
hyposensitivity to reward in depression and dysphoria has been found in behavioral and neuroimaging studies. |
2015-11-16 |
2023-08-13 |
human |
| Jessica Franzen, Kerstin Brinkman. Blunted cardiovascular reactivity in dysphoria during reward and punishment anticipation. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. vol 95. issue 3. 2015-11-16. PMID:25462217. |
the present study aimed at investigating reward and punishment responsiveness in subclinical depression from an effort mobilization perspective. |
2015-11-16 |
2023-08-13 |
human |
| N Lally, A C Nugent, D A Luckenbaugh, R Ameli, J P Roiser, C A Zarat. Anti-anhedonic effect of ketamine and its neural correlates in treatment-resistant bipolar depression. Translational psychiatry. vol 4. 2015-11-02. PMID:25313512. |
however, evidence suggests that standard treatments for depression do little to alleviate the symptoms of anhedonia and may cause reward blunting. |
2015-11-02 |
2023-08-13 |
Not clear |
| Jennifer D Zwicker, Yong Zhang, Jun Ren, Mark R Hutchinson, Kenner C Rice, Linda R Watkins, John J Greer, Gregory D Fun. Glial TLR4 signaling does not contribute to opioid-induced depression of respiration. Journal of applied physiology (Bethesda, Md. : 1985). vol 117. issue 8. 2015-10-30. PMID:25103966. |
glial activation is also hypothesized as pivotal in opioid-mediated reward and tolerance and as a contributor to opioid-mediated respiratory depression. |
2015-10-30 |
2023-08-13 |
mouse |
| Roberto Goya-Maldonado, Kristina Weber, Sarah Trost, Esther Diekhof, Maria Keil, Peter Dechent, Oliver Grube. Dissociating pathomechanisms of depression with fMRI: bottom-up or top-down dysfunctions of the reward system. European archives of psychiatry and clinical neuroscience. vol 265. issue 1. 2015-10-26. PMID:25327829. |
dissociating pathomechanisms of depression with fmri: bottom-up or top-down dysfunctions of the reward system. |
2015-10-26 |
2023-08-13 |
Not clear |
| Roberto Goya-Maldonado, Kristina Weber, Sarah Trost, Esther Diekhof, Maria Keil, Peter Dechent, Oliver Grube. Dissociating pathomechanisms of depression with fMRI: bottom-up or top-down dysfunctions of the reward system. European archives of psychiatry and clinical neuroscience. vol 265. issue 1. 2015-10-26. PMID:25327829. |
depression is a debilitating psychiatric disorder characterized among other aspects by the inability to properly experience or respond to reward. |
2015-10-26 |
2023-08-13 |
Not clear |
| Roberto Goya-Maldonado, Kristina Weber, Sarah Trost, Esther Diekhof, Maria Keil, Peter Dechent, Oliver Grube. Dissociating pathomechanisms of depression with fMRI: bottom-up or top-down dysfunctions of the reward system. European archives of psychiatry and clinical neuroscience. vol 265. issue 1. 2015-10-26. PMID:25327829. |
however, it remains unclear whether patients with depression present impaired reward system due to abnormal modulatory mechanisms. |
2015-10-26 |
2023-08-13 |
Not clear |
| Daniel G Dillon, Isabelle M Rosso, Pia Pechtel, William D S Killgore, Scott L Rauch, Diego A Pizzagall. Peril and pleasure: an rdoc-inspired examination of threat responses and reward processing in anxiety and depression. Depression and anxiety. vol 31. issue 3. 2015-10-23. PMID:24151118. |
peril and pleasure: an rdoc-inspired examination of threat responses and reward processing in anxiety and depression. |
2015-10-23 |
2023-08-12 |
Not clear |
| Daniel G Dillon, Isabelle M Rosso, Pia Pechtel, William D S Killgore, Scott L Rauch, Diego A Pizzagall. Peril and pleasure: an rdoc-inspired examination of threat responses and reward processing in anxiety and depression. Depression and anxiety. vol 31. issue 3. 2015-10-23. PMID:24151118. |
in addition to its basic scientific value, a better understanding of interactions between the neural systems that mediate threat and reward responses may offer relief from the burdensome condition of anxious depression. |
2015-10-23 |
2023-08-12 |
Not clear |
| Robin Nusslock, Christina B Young, Katherine S F Damm. Elevated reward-related neural activation as a unique biological marker of bipolar disorder: assessment and treatment implications. Behaviour research and therapy. vol 62. 2015-10-15. PMID:25241675. |
by contrast, unipolar depression (without a history of hypomania/mania) is characterized by decreased reward responsivity and decreased reward-related neural activation. |
2015-10-15 |
2023-08-13 |
Not clear |
| Robin Nusslock, Christina B Young, Katherine S F Damm. Elevated reward-related neural activation as a unique biological marker of bipolar disorder: assessment and treatment implications. Behaviour research and therapy. vol 62. 2015-10-15. PMID:25241675. |
collectively, this suggests that risk for bipolar disorder and unipolar depression are characterized by distinct and opposite profiles of reward processing and reward-related neural activation. |
2015-10-15 |
2023-08-13 |
Not clear |
| Daniel G Dillo. The neuroscience of positive memory deficits in depression. Frontiers in psychology. vol 6. 2015-10-07. PMID:26441703. |
unipolar depression is characterized by anhedonia-loss of pleasure-and reward circuit dysfunction, which is believed to reflect negative effects of stress on the mesolimbic dopamine pathway. |
2015-10-07 |
2023-08-13 |
Not clear |
| Gonzalo Arrondo, Nuria Segarra, Antonio Metastasio, Hisham Ziauddeen, Jennifer Spencer, Niels R Reinders, Robert B Dudas, Trevor W Robbins, Paul C Fletcher, Graham K Murra. Reduction in ventral striatal activity when anticipating a reward in depression and schizophrenia: a replicated cross-diagnostic finding. Frontiers in psychology. vol 6. 2015-09-18. PMID:26379600. |
reduction in ventral striatal activity when anticipating a reward in depression and schizophrenia: a replicated cross-diagnostic finding. |
2015-09-18 |
2023-08-13 |
human |