| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ellis Rea, Julia Rummel, Timo T Schmidt, Ravit Hadar, Andreas Heinz, Aleksander A Mathé, Christine Winte. Anti-anhedonic effect of deep brain stimulation of the prefrontal cortex and the dopaminergic reward system in a genetic rat model of depression: an intracranial self-stimulation paradigm study. Brain stimulation. vol 7. issue 1. 2014-08-25. PMID:24139146. |
anti-anhedonic effect of deep brain stimulation of the prefrontal cortex and the dopaminergic reward system in a genetic rat model of depression: an intracranial self-stimulation paradigm study. |
2014-08-25 |
2023-08-12 |
rat |
| Ellis Rea, Julia Rummel, Timo T Schmidt, Ravit Hadar, Andreas Heinz, Aleksander A Mathé, Christine Winte. Anti-anhedonic effect of deep brain stimulation of the prefrontal cortex and the dopaminergic reward system in a genetic rat model of depression: an intracranial self-stimulation paradigm study. Brain stimulation. vol 7. issue 1. 2014-08-25. PMID:24139146. |
one of the two core symptoms of major depression (md), whether uni- or bipolar, is the inability to experience pleasure, suggested to be triggered by dysregulation within the brain reward system. |
2014-08-25 |
2023-08-12 |
rat |
| Thomas E Schlaepfer, Bettina H Bewernic. Neuromodulation for treatment resistant depression: state of the art and recommendations for clinical and scientific conduct. Brain topography. vol 27. issue 1. 2014-08-18. PMID:24072617. |
in other words, whereas existing depression treatments approach this disease as a general brain dysfunction, a more complete and appropriate treatment will arise from thinking of depression as a dysfunction of specific brain networks that mediate mood and reward signals (berton and nestler, nat rev neurosci 7 (2):137-151, 2006; krishnan and nestler, nature 455(7215):894-902, 2008). |
2014-08-18 |
2023-08-12 |
human |
| Chris Vriend, Tommy Pattij, Ysbrand D van der Werf, Pieter Voorn, Jan Booij, Sonja Rutten, Henk W Berendse, Odile A van den Heuve. Depression and impulse control disorders in Parkinson's disease: two sides of the same coin? Neuroscience and biobehavioral reviews. vol 38. 2014-08-08. PMID:24239733. |
finally, we propose a neurobiological model that identifies ventral striatal dopaminergic denervation as a common underlying neurobiological substrate of depression and icd and subsequent dysfunction of reward and motivation-related brain areas. |
2014-08-08 |
2023-08-12 |
Not clear |
| Joseph P Huston, Maria A de Souza Silva, Mara Komorowski, Daniela Schulz, Bianca Topi. Animal models of extinction-induced depression: loss of reward and its consequences. Neuroscience and biobehavioral reviews. vol 37. issue 9 Pt A. 2014-08-07. PMID:23466533. |
animal models of extinction-induced depression: loss of reward and its consequences. |
2014-08-07 |
2023-08-12 |
human |
| Joseph P Huston, Maria A de Souza Silva, Mara Komorowski, Daniela Schulz, Bianca Topi. Animal models of extinction-induced depression: loss of reward and its consequences. Neuroscience and biobehavioral reviews. vol 37. issue 9 Pt A. 2014-08-07. PMID:23466533. |
during extinction after positive reinforcement the important indices for extinction-induced depression are the withdrawal from the former site of reward, biting behavior and rearing up on the hind legs. |
2014-08-07 |
2023-08-12 |
human |
| Henry W Chase, Robin Nusslock, Jorge Rc Almeida, Erika E Forbes, Edmund J LaBarbara, Mary L Phillip. Dissociable patterns of abnormal frontal cortical activation during anticipation of an uncertain reward or loss in bipolar versus major depression. Bipolar disorders. vol 15. issue 8. 2014-07-23. PMID:24148027. |
dissociable patterns of abnormal frontal cortical activation during anticipation of an uncertain reward or loss in bipolar versus major depression. |
2014-07-23 |
2023-08-12 |
Not clear |
| Gian Marco Leggio, Salvatore Salomone, Claudio Bucolo, Chiara Platania, Vincenzo Micale, Filippo Caraci, Filippo Drag. Dopamine D(3) receptor as a new pharmacological target for the treatment of depression. European journal of pharmacology. vol 719. issue 1-3. 2014-07-02. PMID:23872400. |
activity of mesolimbic dopamine neurons in the reward circuit is a key determinant of behavioral susceptibility/resilience to chronic stress, which plays a central role in the pathogenesis of depression. |
2014-07-02 |
2023-08-12 |
Not clear |
| Anita Must, Szatmar Horvath, Viola L Nemeth, Zoltan Jank. The Iowa Gambling Task in depression - what have we learned about sub-optimal decision-making strategies? Frontiers in psychology. vol 4. 2014-06-24. PMID:24133474. |
our earlier study found patients with depression to show a preference for larger reward as measured by the iowa gambling task (igt). |
2014-06-24 |
2023-08-12 |
Not clear |
| Peng Zhong, Xiaojie Liu, Zhen Zhang, Ying Hu, Sarah J Liu, Martha Lezama-Ruiz, Milan Joksimovic, Qing-song Li. Cyclin-dependent kinase 5 in the ventral tegmental area regulates depression-related behaviors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 18. 2014-06-23. PMID:24790206. |
dopamine neurons in the ventral tegmental area (vta) govern reward and motivation and dysregulated dopaminergic transmission may account for anhedonia and other symptoms of depression. |
2014-06-23 |
2023-08-13 |
mouse |
| Pia Pechtel, Sunny J Dutra, Elena L Goetz, Diego A Pizzagall. Blunted reward responsiveness in remitted depression. Journal of psychiatric research. vol 47. issue 12. 2014-06-05. PMID:24064208. |
blunted reward responsiveness in remitted depression. |
2014-06-05 |
2023-08-12 |
Not clear |
| Michio Takahashi, Yukihiko Shirayama, Katsumasa Muneoka, Masatoshi Suzuki, Koichi Sato, Kenji Hashimot. Low openness on the revised NEO personality inventory as a risk factor for treatment-resistant depression. PloS one. vol 8. issue 9. 2014-05-16. PMID:24019864. |
recently, we reported that low reward dependence, and to a lesser extent, low cooperativeness in the temperature and character inventory (tci) may be risk factors for treatment-resistant depression. |
2014-05-16 |
2023-08-12 |
Not clear |
| Crystal Edler Schiller, Jared Minkel, Moria J Smoski, Gabriel S Dichte. Remitted major depression is characterized by reduced prefrontal cortex reactivity to reward loss. Journal of affective disorders. vol 151. issue 2. 2014-05-13. PMID:23835103. |
remitted major depression is characterized by reduced prefrontal cortex reactivity to reward loss. |
2014-05-13 |
2023-08-12 |
Not clear |
| Kerstin Brinkmann, Jessica Franze. Not everyone's heart contracts to reward: Insensitivity to varying levels of reward in dysphoria. Biological psychology. vol 94. issue 2. 2014-05-13. PMID:23872164. |
reward insensitivity in depression and dysphoria has been demonstrated by self-report, behavioral, and neuroscience data. |
2014-05-13 |
2023-08-12 |
human |
| Nir Lipsman, Blake Woodside, Andres M Lozan. Evaluating the potential of deep brain stimulation for treatment-resistant anorexia nervosa. Handbook of clinical neurology. vol 116. 2014-04-16. PMID:24112901. |
abnormal reward processing, compulsive hyperactivity, chronic anxiety, and depression, all suggest that anorexia nervosa shares much in common with other conditions, such as major depression and obsessive-compulsive disorder, for which surgical therapy with deep brain stimulation (dbs) has been tried, with promising results. |
2014-04-16 |
2023-08-12 |
Not clear |
| Steven J Shabel, Ryan T Murphy, Roberto Malino. Negative learning bias is associated with risk aversion in a genetic animal model of depression. Frontiers in human neuroscience. vol 8. 2014-01-29. PMID:24474914. |
the lateral habenula (lhb) is activated by aversive stimuli and the omission of reward, inhibited by rewarding stimuli and is hyperactive in helpless rats-an animal model of depression. |
2014-01-29 |
2023-08-12 |
rat |
| Bo Jiang, Wei Wang, Fang Wang, Zhuang-Li Hu, Jun-Li Xiao, Si Yang, Jing Zhang, Xiao-Zhong Peng, Jin-Hui Wang, Jian-Guo Che. The stability of NR2B in the nucleus accumbens controls behavioral and synaptic adaptations to chronic stress. Biological psychiatry. vol 74. issue 2. 2014-01-17. PMID:23260228. |
it has been demonstrated that the glutamatergic system in nac plays an important role in the reward pathway, dysfunction of which would cause anhedonia, a core symptom of depression. |
2014-01-17 |
2023-08-12 |
Not clear |
| S R Kuhlmann, H Walter, T E Schläpfe. [The neurobiology of anhedonia. The pathophysiology of an important symptom in depressive disorders]. Der Nervenarzt. vol 84. issue 5. 2014-01-08. PMID:23086440. |
the hypothesis that functional changes within the mesolimbic reward system could represent the neural correlate of anhedonia has contributed to a new concept of depressive disorders and allows testing of new therapeutic options for patients suffering from very resistant forms of depression. |
2014-01-08 |
2023-08-12 |
Not clear |
| V S Chib, K Yun, H Takahashi, S Shimoj. Noninvasive remote activation of the ventral midbrain by transcranial direct current stimulation of prefrontal cortex. Translational psychiatry. vol 3. 2013-12-23. PMID:23756377. |
the midbrain lies deep within the brain and has an important role in reward, motivation, movement and the pathophysiology of various neuropsychiatric disorders such as parkinson's disease, schizophrenia, depression and addiction. |
2013-12-23 |
2023-08-12 |
human |
| Scott J Russo, Eric J Nestle. The brain reward circuitry in mood disorders. Nature reviews. Neuroscience. vol 14. issue 9. 2013-12-11. PMID:23942470. |
this review synthesizes recent data from human and rodent studies from which emerges a circuit-level framework for understanding reward deficits in depression. |
2013-12-11 |
2023-08-12 |
human |