| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yun-Hui Li, Chun-Hu Zhang, Juan Qiu, Su-E Wang, Sui-Yu Hu, Xi Huang, Ying Xie, Yang Wang, Tian-Li Chen. Antidepressant-like effects of Chaihu-Shugan-San via SAPK/JNK signal transduction in rat models of depression. Pharmacognosy magazine. vol 10. issue 39. 2014-09-11. PMID:25210314. |
c-jun amino-terminal kinase (jnk/sapk) signal transduction plays a key role in the apoptosis of nerve cells, be reported closely correlated with depression. |
2014-09-11 |
2023-08-13 |
rat |
| Michael Berk, Olivia M Dean, Sue M Cotton, Susan Jeavons, Michelle Tanious, Kristy Kohlmann, Karen Hewitt, Kirsteen Moss, Christine Allwang, Ian Schapkaitz, Jenny Robbins, Heidi Cobb, Felicity Ng, Seetal Dodd, Ashley I Bush, Gin S Malh. The efficacy of adjunctive N-acetylcysteine in major depressive disorder: a double-blind, randomized, placebo-controlled trial. The Journal of clinical psychiatry. vol 75. issue 6. 2014-08-25. PMID:25004186. |
n-acetylcysteine (nac) is a redox-active glutathione precursor that decreases inflammatory cytokines, modulates glutamate, promotes neurogenesis, and decreases apoptosis, all of which contribute to the neurobiology of depression. |
2014-08-25 |
2023-08-13 |
Not clear |
| Jinhua Fu, Yong Liu, Qingyong Wang, Jingping Zha. [Effect of Shuganjieyu capsules on neuronal apoptosis in hippocampal CA3 area and the expression of caspase-3 in the brain of rat depression model]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 37. issue 12. 2014-08-01. PMID:23281372. |
to evaluate the effect of "shuganjieyu" (sgjy) capsules on neuronal apoptosis in hippocampal ca3 area and the expression of caspase-3 in the brain of rat depression model, and to investigate its pharmacological mechanisms in depression treatment. |
2014-08-01 |
2023-08-12 |
rat |
| Jinhua Fu, Yong Liu, Qingyong Wang, Jingping Zha. [Effect of Shuganjieyu capsules on neuronal apoptosis in hippocampal CA3 area and the expression of caspase-3 in the brain of rat depression model]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 37. issue 12. 2014-08-01. PMID:23281372. |
[effect of shuganjieyu capsules on neuronal apoptosis in hippocampal ca3 area and the expression of caspase-3 in the brain of rat depression model]. |
2014-08-01 |
2023-08-12 |
rat |
| Walter Swardfager, Nathan Herrmann, Graham Mazereeuw, Kyle Goldberger, Tetsuhiro Harimoto, Krista L Lanctô. Zinc in depression: a meta-analysis. Biological psychiatry. vol 74. issue 12. 2014-06-30. PMID:23806573. |
zinc is an essential micronutrient with diverse biological roles in cell growth, apoptosis and metabolism, and in the regulation of endocrine, immune, and neuronal functions implicated in the pathophysiology of depression. |
2014-06-30 |
2023-08-12 |
human |
| Toko Ohira, Ryo Ando, Tsubasa Saito, Megumi Yahata, Yosuke Oshima, Kazutoshi Tamur. Busulfan-induced pathological changes of the cerebellar development in infant rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 65. issue 6. 2014-02-13. PMID:23276622. |
in the egl of the busulfan group, apoptotic granular cells increased at 2 dat simultaneously with increased numbers of p53- and p21-positive cells while mitotic granular cells decreased, suggesting an occurrence of p53-related apoptosis and depression of proliferative activity in granular cells. |
2014-02-13 |
2023-08-12 |
rat |
| Ke-Li Tsai, Hsin-Jen Liang, Zheng-Dao Yang, Sheng-I Lue, Shaw-Lang Yang, Chin Hs. Early inactivation of PKCε associates with late mitochondrial translocation of Bad and apoptosis in ventricle of septic rat. The Journal of surgical research. vol 186. issue 1. 2014-02-07. PMID:24011917. |
sepsis is usually accompanied by cardiomyocyte apoptosis and myocardial depression. |
2014-02-07 |
2023-08-12 |
rat |
| Li Li, Bang-Chuan Hu, Chang-Qin Chen, Shi-Jin Gong, Yi-Hua Yu, Hai-Wen Dai, Jing Ya. Role of mitochondrial damage during cardiac apoptosis in septic rats. Chinese medical journal. vol 126. issue 10. 2013-12-13. PMID:23673100. |
myocardial apoptosis is involved in the pathogenesis of sepsis-related myocardial depression. |
2013-12-13 |
2023-08-12 |
rat |
| Yiming Wang, Xingde Liu, Dongfeng Zhang, Jianhui Chen, Shuzheng Liu, Michael Ber. The effects of apoptosis vulnerability markers on the myocardium in depression after myocardial infarction. BMC medicine. vol 11. 2013-07-17. PMID:23394076. |
the effects of apoptosis vulnerability markers on the myocardium in depression after myocardial infarction. |
2013-07-17 |
2023-08-12 |
Not clear |
| Yiming Wang, Xingde Liu, Dongfeng Zhang, Jianhui Chen, Shuzheng Liu, Michael Ber. The effects of apoptosis vulnerability markers on the myocardium in depression after myocardial infarction. BMC medicine. vol 11. 2013-07-17. PMID:23394076. |
this study aimed to attempt to confirm the effects of apoptosis vulnerability markers on the myocardium in a model of depression after myocardial infarction. |
2013-07-17 |
2023-08-12 |
Not clear |
| N N Dygalo, G T Shishkin. [Anti-apoptotic protein enhances resilience to psychoemotional effects of stress]. Uspekhi fiziologicheskikh nauk. vol 44. issue 2. 2013-07-12. PMID:23789349. |
stress predisposes to depression by enhancing apoptosis and reducing neurogenesis in the brain. |
2013-07-12 |
2023-08-12 |
Not clear |
| Song-qiang Xie, Lei-lei Zhang, Tao Yang, Ying Ma, Ya-hong Zhang, Qian Li, Jian-hong Wang, Jin Zhao, Chao-jie Wan. [Acetylsalicylic acid strengthens the effects of ANISpm against hepatocellular carcinoma and its molecular mechanism]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 46. issue 9. 2013-05-06. PMID:22121773. |
the combination treatment strongly inhibited cell proliferation, induced cell apoptosis in hepg2 cells and h22 hepatoma cells, which was mediated by enhanced anispm uptake via up-regulation of spermidine/spermine n1-acetyltransferase (ssat) and depression of intracellular polyamine. |
2013-05-06 |
2023-08-12 |
Not clear |
| Michael Maes, Ivana Mihaylova, Marta Kubera, Jean-Claude Leunis, Frank N M Twisk, Michel Geffar. IgM-mediated autoimmune responses directed against anchorage epitopes are greater in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) than in major depression. Metabolic brain disease. vol 27. issue 4. 2013-05-03. PMID:22614823. |
intracellular signal transduction, cellular differentiation and apoptosis, but their impact may be more important in me/cfs than in depression. |
2013-05-03 |
2023-08-12 |
Not clear |
| Kim Gilbert, Jessica Arseneault-Bréard, Fabio Flores Monaco, Alexanne Beaudoin, Thierno Madjou Bah, Thomas A Tompkins, Roger Godbout, Guy Roussea. Attenuation of post-myocardial infarction depression in rats by n-3 fatty acids or probiotics starting after the onset of reperfusion. The British journal of nutrition. vol 109. issue 1. 2013-02-26. PMID:23068715. |
these results indicate that a high-pufa n-3 diet or the administration of probiotics, starting after the onset of reperfusion, are beneficial to attenuate apoptosis in the limbic system and post-mi depression in the rat. |
2013-02-26 |
2023-08-12 |
rat |
| Song-qiang Xie, Ya-hong Zhang, Qian Li, Jian-hong Wang, Jing-hua Li, Jin Zhao, Chao-jie Wan. COX-2-independent induction of apoptosis by celecoxib and polyamine naphthalimide conjugate mediated by polyamine depression in colorectal cancer cell lines. International journal of colorectal disease. vol 27. issue 7. 2012-10-17. PMID:22159752. |
cox-2-independent induction of apoptosis by celecoxib and polyamine naphthalimide conjugate mediated by polyamine depression in colorectal cancer cell lines. |
2012-10-17 |
2023-08-12 |
human |
| Nikolay N Dygalo, Tatyana S Kalinina, Veta V Bulygina, Galina T Shishkin. Increased expression of the anti-apoptotic protein Bcl-xL in the brain is associated with resilience to stress-induced depression-like behavior. Cellular and molecular neurobiology. vol 32. issue 5. 2012-10-17. PMID:22278304. |
stress may predispose individuals toward depression through down-regulation of neurogenesis and an increase in apoptosis in the brain. |
2012-10-17 |
2023-08-12 |
rat |
| Fengfeng Ping, Jing Shang, Jia Zhou, Hongmei Zhang, Luyong Zhan. 5-HT(1A) receptor and apoptosis contribute to interferon-α-induced "depressive-like" behavior in mice. Neuroscience letters. vol 514. issue 2. 2012-09-14. PMID:22414862. |
recently, serotonin 1a (5-ht(1a)) receptor and cellular apoptosis are involved in mechanism(s) contributing to depression. |
2012-09-14 |
2023-08-12 |
mouse |
| Xiaofei Wang, Yan Zhang, Xiwen Zhang, Wenxia Tian, Wenli Feng, Tingmei Che. The curcumin analogue hydrazinocurcumin exhibits potent suppressive activity on carcinogenicity of breast cancer cells via STAT3 inhibition. International journal of oncology. vol 40. issue 4. 2012-08-31. PMID:22179587. |
the results demonstrated that compared to curcumin, hc was more effective in inhibiting stat3 phosphorylation and downregulation of an array of stat3 downstream targets which contributed to suppression of cell proliferation, loss of colony formation, depression of cell migration and invasion as well as induction of cell apoptosis. |
2012-08-31 |
2023-08-12 |
human |
| Jessica Arseneault-Bréard, Isabelle Rondeau, Kim Gilbert, Stéphanie-Anne Girard, Thomas A Tompkins, Roger Godbout, Guy Roussea. Combination of Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 reduces post-myocardial infarction depression symptoms and restores intestinal permeability in a rat model. The British journal of nutrition. vol 107. issue 12. 2012-08-20. PMID:21933458. |
myocardial infarction (mi) in rats is accompanied by apoptosis in the limbic system and a behavioural syndrome similar to models of depression. |
2012-08-20 |
2023-08-12 |
rat |
| Natalia Battista, Maria A Meloni, Monica Bari, Nicolina Mastrangelo, Grazia Galleri, Cinzia Rapino, Enrico Dainese, Alessandro Finazzi Agrò, Proto Pippia, Mauro Maccarron. 5-Lipoxygenase-dependent apoptosis of human lymphocytes in the International Space Station: data from the ROALD experiment. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 26. issue 5. 2012-06-29. PMID:22253478. |
the goal of the role of apoptosis in lymphocyte depression (roald) experiment, flown on the international space station as part of the bio-4 mission of the european space agency, was to ascertain the induction of apoptosis in human lymphocytes under authentic microgravity, and to elucidate the possible involvement of 5-lox. |
2012-06-29 |
2023-08-12 |
human |