| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing Liu, Wenjuan Deng, Lei Fan, Limin Tian, Liying Jin, Zhisheng Jin, Qian Guo, Yanjia Xu, Ning L. The role of radix hedysari polysaccharide on the human umbilical vein endothelial cells (HUVECs) induced by high glucose. European journal of internal medicine. vol 23. issue 3. 2012-06-26. PMID:22385890. |
in this study, we investigated the effect of radix hedysari polysaccharide (hps) on the depression of apoptosis of human umbilical vein endothelial cells (huvecs) induced by high glucose. |
2012-06-26 |
2023-08-12 |
human |
| Shengfen Tu, Xiaoyi Wang, Fei Yang, Bailin Chen, Shengde Wu, Wenfei He, Xingang Yuan, Hua Zhang, Ping Chen, Guanghui We. Propofol induces neuronal apoptosis in infant rat brain under hypoxic conditions. Brain research bulletin. vol 86. issue 1-2. 2012-04-04. PMID:21756983. |
in addition, propofol indirectly induced apoptosis through hypoxia resulting from respiratory depression under air or hypoxic conditions, which was determined by elevated expression of caspase-3, increased tunel-positive cells, ultrastructural changes of neuronal cell death and loss of nissl staining neuronal in infant sd rat brains. |
2012-04-04 |
2023-08-12 |
rat |
| Jacques Noël, Guillaume Sandoz, Florian Lesag. Molecular regulations governing TREK and TRAAK channel functions. Channels (Austin, Tex.). vol 5. issue 5. 2012-02-14. PMID:21829087. |
they are involved in cellular mechanisms of apoptosis, vasodilatation, anesthesia, pain, neuroprotection and depression. |
2012-02-14 |
2023-08-12 |
Not clear |
| Deyu Yang, Xia Liu, Rufang Zhang, Ke Cheng, Jun Mu, Liang Fang, Peng Xi. Increased apoptosis and different regulation of pro-apoptosis protein bax and anti-apoptosis protein bcl-2 in the olfactory bulb of a rat model of depression. Neuroscience letters. vol 504. issue 1. 2012-02-14. PMID:21903151. |
in this study, we investigated the apoptosis in the ob of a chronic unpredictable mild stress (cums) rat model of depression using terminal deoxynucleotidyl transferase-mediated dutp nick end labeling (tunel) staining. |
2012-02-14 |
2023-08-12 |
rat |
| Deyu Yang, Xia Liu, Rufang Zhang, Ke Cheng, Jun Mu, Liang Fang, Peng Xi. Increased apoptosis and different regulation of pro-apoptosis protein bax and anti-apoptosis protein bcl-2 in the olfactory bulb of a rat model of depression. Neuroscience letters. vol 504. issue 1. 2012-02-14. PMID:21903151. |
increased apoptosis and different regulation of pro-apoptosis protein bax and anti-apoptosis protein bcl-2 in the olfactory bulb of a rat model of depression. |
2012-02-14 |
2023-08-12 |
rat |
| Marta Kubera, Ewa Obuchowicz, Lisa Goehler, Joanna Brzeszcz, Michael Mae. In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 3. 2012-01-06. PMID:20828592. |
in animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression. |
2012-01-06 |
2023-08-12 |
Not clear |
| Michaela C Pascoe, Sheila G Crewther, Leeanne M Carey, David P Crewthe. What you eat is what you are -- a role for polyunsaturated fatty acids in neuroinflammation induced depression? Clinical nutrition (Edinburgh, Scotland). vol 30. issue 4. 2011-12-15. PMID:21621887. |
depression related naturally occurring cell death (apoptosis) is thought to be mediated by excitotoxicity and free radicals that appear in the brain immediately following any inflammatory or ischemic damage, and increases the likelihood of clinically defined depression. |
2011-12-15 |
2023-08-12 |
Not clear |
| R C Shelton, J Claiborne, M Sidoryk-Wegrzynowicz, R Reddy, M Aschner, D A Lewis, K Mirnic. Altered expression of genes involved in inflammation and apoptosis in frontal cortex in major depression. Molecular psychiatry. vol 16. issue 7. 2011-11-03. PMID:20479761. |
altered expression of genes involved in inflammation and apoptosis in frontal cortex in major depression. |
2011-11-03 |
2023-08-12 |
human |
| Na Lu, Yiguo Sun, Xiaoxiang Zhen. Orientin-induced cardioprotection against reperfusion is associated with attenuation of mitochondrial permeability transition. Planta medica. vol 77. issue 10. 2011-10-20. PMID:21283956. |
here, our results indicate that the protective effect of orientin in h9c2 cells subjected to i/r injury is associated with depression of the mptp opening, resultant mitochondrial dysfunction, and apoptosis. |
2011-10-20 |
2023-08-12 |
Not clear |
| Michaela C Pascoe, Sheila G Crewther, Leeanne M Carey, David P Crewthe. Inflammation and depression: why poststroke depression may be the norm and not the exception. International journal of stroke : official journal of the International Stroke Society. vol 6. issue 2. 2011-06-27. PMID:21371275. |
particular attention has been paid to cytokine-driven intrinsic apoptosis factors, including intracellular calcium, glutamate excitotoxicity and free radicals that appear in the brain following ischaemic damage and whose presence significantly increases the likelihood of clinically defined depression. |
2011-06-27 |
2023-08-12 |
Not clear |
| R Liu, L Zhang, X Lan, L Li, T-T Zhang, J-H Sun, G-H D. Protection by borneol on cortical neurons against oxygen-glucose deprivation/reperfusion: involvement of anti-oxidation and anti-inflammation through nuclear transcription factor κappaB signaling pathway. Neuroscience. vol 176. 2011-06-01. PMID:21168474. |
the mechanisms of this reversal from ogd/r may be involved in the alleviation of intracellular ros and inos/no pathway, inhibition of inflammatory factor release and depression of caspase-related apoptosis. |
2011-06-01 |
2023-08-12 |
Not clear |
| Xinliang Mao, Tingjun Hou, Biyin Cao, Wenjie Wang, Zhihua Li, Suning Chen, Min Fei, Rose Hurren, Marcela Gronda, Depei Wu, Suzanne Trudel, Aaron D Schimme. The tricyclic antidepressant amitriptyline inhibits D-cyclin transactivation and induces myeloma cell apoptosis by inhibiting histone deacetylases: in vitro and in silico evidence. Molecular pharmacology. vol 79. issue 4. 2011-05-31. PMID:21220410. |
amitriptyline is a classic tricyclic antidepressant (tca) and has been used to treat the depression and anxiety of patients with cancer, but its relevance to cancer cell apoptosis is not known. |
2011-05-31 |
2023-08-12 |
Not clear |
| Yadong Liu, Shiping Ma, Rong Q. SCLM, total saponins extracted from Chaihu-jia-longgu-muli-tang, reduces chronic mild stress-induced apoptosis in the hippocampus in mice. Pharmaceutical biology. vol 48. issue 8. 2011-05-17. PMID:20673169. |
in contrast, antidepressant treatment significantly reduces apoptosis in the dentate granule cell layer and subgranular zone in animal models of depression. |
2011-05-17 |
2023-08-12 |
mouse |
| Wei Dai, Wei-Dong Li, Jun L. [Effect of electroacupuncture on hippocampal apoptosis and JNK signal pathway in chronic stress depression rats]. Zhen ci yan jiu = Acupuncture research. vol 35. issue 5. 2011-02-24. PMID:21235059. |
to observe the effect of electroacupuncture (ea) on hippocampal apoptosis and c-jun n-terminal kinase (jnk) signal pathway in chronic stress depression rats so as to study its mechanism underlying acupuncture-induced improvement of depression. |
2011-02-24 |
2023-08-12 |
rat |
| Wei Dai, Wei-Dong Li, Jun L. [Effect of electroacupuncture on hippocampal apoptosis and JNK signal pathway in chronic stress depression rats]. Zhen ci yan jiu = Acupuncture research. vol 35. issue 5. 2011-02-24. PMID:21235059. |
[effect of electroacupuncture on hippocampal apoptosis and jnk signal pathway in chronic stress depression rats]. |
2011-02-24 |
2023-08-12 |
rat |
| Jennifer N Griffin, Daniel Pinali, Kaylan Olds, Na Lu, Lindsay Appleby, Louis Doan, Michelle A Lan. 13-Cis-retinoic acid decreases hypothalamic cell number in vitro. Neuroscience research. vol 68. issue 3. 2011-01-21. PMID:20708044. |
in fact, apoptosis of hypothalamic neurons may lead to depression after myocardial infarction. |
2011-01-21 |
2023-08-12 |
mouse |
| Galina T Shishkina, Tatyana S Kalinina, Inna V Berezova, Veta V Bulygina, Nikolay N Dygal. Resistance to the development of stress-induced behavioral despair in the forced swim test associated with elevated hippocampal Bcl-xl expression. Behavioural brain research. vol 213. issue 2. 2010-10-19. PMID:20457187. |
stress may predispose individuals toward depression through down-regulation of neurogenesis and increase in apoptosis in the brain. |
2010-10-19 |
2023-08-12 |
human |
| Kay L H Wu, Chin Hsu, Julie Y H Cha. Nitric oxide and superoxide anion differentially activate poly(ADP-ribose) polymerase-1 and Bax to induce nuclear translocation of apoptosis-inducing factor and mitochondrial release of cytochrome c after spinal cord injury. Journal of neurotrauma. vol 26. issue 7. 2010-09-22. PMID:19473058. |
we reported previously that complete spinal cord transection (sct) results in depression of mitochondrial respiratory chain enzyme activity that triggers apoptosis via sequential activations of apoptosis-inducing factor (aif)- and caspase-dependent cascades in the injured spinal cord. |
2010-09-22 |
2023-08-12 |
rat |
| Subhendu Mukherjee, Diptarka Ray, Mario Falchi, Aldo Bertelli, Elena Pini, Dipak K Da. Cardioprotection with the parrodiene 2,4,6-octatrienal and its potassium salt through activation of the Akt-Bcl-2 survival pathway. Journal of natural products. vol 72. issue 5. 2010-07-20. PMID:19326879. |
ischemia/reperfusion resulted in a significant amount of tissue injury, cardiomyocyte apoptosis, and depression in hemodynamic functions. |
2010-07-20 |
2023-08-12 |
rat |
| Li Wang, Fang Yin, Yulei Du, Bei Chen, Shuhui Liang, Yongguo Zhang, Wenqi Du, Kaichun Wu, Jie Ding, Daiming Fa. Depression of MAD2 inhibits apoptosis and increases proliferation and multidrug resistance in gastric cancer cells by regulating the activation of phosphorylated survivin. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 31. issue 3. 2010-06-11. PMID:20440596. |
depression of mad2 inhibits apoptosis and increases proliferation and multidrug resistance in gastric cancer cells by regulating the activation of phosphorylated survivin. |
2010-06-11 |
2023-08-12 |
mouse |