| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexandros G Kokkosis, Miguel M Madeira, Matthew R Mullahy, Stella E Tsirk. Chronic stress disrupts the homeostasis and progeny progression of oligodendroglial lineage cells, associating immune oligodendrocytes with prefrontal cortex hypomyelination. Molecular psychiatry. 2022-03-18. PMID:35301426. |
exposure to chronic stress results in opc morphological impairments, excessive oxidative stress, and oligodendroglial apoptosis, implicating integrative-stress responses in depression. |
2022-03-18 |
2023-08-13 |
mouse |
| Junni Yan, Fuping Zhang, Le Niu, Xiaonan Wang, Xinxin Lu, Chaoyue Ma, Chencheng Zhang, Jinggui Song, Zhaohui Zhan. High-frequency repetitive transcranial magnetic stimulation mitigates depression-like behaviors in CUMS-induced rats via FGF2/FGFR1/p-ERK signaling pathway. Brain research bulletin. 2022-03-05. PMID:35247488. |
substantial evidence has accumulated indicating that neurotrophin dysfunction and neuronal apoptosis play a role in the development of depression. |
2022-03-05 |
2023-08-13 |
rat |
| Junni Yan, Fuping Zhang, Le Niu, Xiaonan Wang, Xinxin Lu, Chaoyue Ma, Chencheng Zhang, Jinggui Song, Zhaohui Zhan. High-frequency repetitive transcranial magnetic stimulation mitigates depression-like behaviors in CUMS-induced rats via FGF2/FGFR1/p-ERK signaling pathway. Brain research bulletin. 2022-03-05. PMID:35247488. |
these results suggest that rtms treatment can improve depression-like behavior, attenuate neural apoptosis, and reverse reduction of astrocytes in a rat model of depression. |
2022-03-05 |
2023-08-13 |
rat |
| Rongchun Wang, Qingyu Ren, Daili Gao, Yam Nath Paudel, Xia Li, Lizhen Wang, Pengyu Zhang, Baokun Wang, Xueliang Shang, Meng Ji. Ameliorative effect of Gastrodia elata Blume extracts on depression in zebrafish and cellular models through modulating reticulon 4 receptors and apoptosis. Journal of ethnopharmacology. 2022-01-29. PMID:35092824. |
ameliorative effect of gastrodia elata blume extracts on depression in zebrafish and cellular models through modulating reticulon 4 receptors and apoptosis. |
2022-01-29 |
2023-08-13 |
zebrafish |
| Yosuke Kanno, Kaho Tsuchida, Chihiro Maruyama, Kyoko Hori, Hanako Teramura, Shiho Asahi, Osamu Matsuo, Kei-Ichi Ozak. Alpha2-antiplasmin deficiency affects depression and anxiety-like behavior and apoptosis induced by stress in mice. Journal of basic and clinical physiology and pharmacology. 2021-12-16. PMID:34913624. |
alpha2-antiplasmin deficiency affects depression and anxiety-like behavior and apoptosis induced by stress in mice. |
2021-12-16 |
2023-08-13 |
mouse |
| Peng Su, Feng Mao, Jian Zhang, Hui Zhang, MingBo Wang, YanZhao Xu, ZiQiang Tia. Circular RNA UBR1 promotes the proliferation, migration, and invasion but represses apoptosis of lung cancer cells via modulating microRNA-545-5p/SSFA2 axis. Bioengineered. vol 12. issue 2. 2021-12-08. PMID:34787049. |
after transfection with circ-ubr1 low expression vector, upregulation of ssfa2 apparently reversed the depression of reduced circ-ubr1 on cell proliferation, migration, and invasion, and the promotion of cell apoptosis. |
2021-12-08 |
2023-08-13 |
mouse |
| Zhifu Cui, Xiaoxu Shen, Xianxian Zhang, Fugui Li, Felix Kwame Amevor, Qing Zhu, Yan Wang, Diyan Li, Gang Shu, Yaofu Tian, Xiaoling Zha. A functional polymorphism of inhibin alpha subunit at miR-181b-1-3p-binding site regulates proliferation and apoptosis of chicken ovarian granular cells. Cell and tissue research. vol 384. issue 2. 2021-11-24. PMID:33439349. |
additionally, depression of inha increased apoptosis and reduced gc proliferation via a caspase-3-dependent mitochondrial pathway. |
2021-11-24 |
2023-08-13 |
chicken |
| Hasan Karadağ, Görkem Saygılı, Rabia Yüksel, Miraç Barış Usta, Canan Topçuoğlu, Gamze Erzi. Serum TNF- Related Weak Inducer of Apoptosis (TWEAK), TNF- Related Apoptosis-Inducing Ligand (TRAIL) Levels in Patients with Bipolar Depression, Major Depression and a Healthy Control Group. Psychiatria Danubina. vol 33. issue 3. 2021-11-22. PMID:34795172. |
the aim of this study was to investigate the serum tnf-related weak inducer of apoptosis (tweak) and tnf-related apoptosis-inducing ligand (trail) levels in patients with bipolar depression (bd), mdd and a healthy control (hc) group to determine any differences between mdd and bd in terms of inflammation biomarkers. |
2021-11-22 |
2023-08-13 |
Not clear |
| Hasan Karadağ, Görkem Saygılı, Rabia Yüksel, Miraç Barış Usta, Canan Topçuoğlu, Gamze Erzi. Serum TNF- Related Weak Inducer of Apoptosis (TWEAK), TNF- Related Apoptosis-Inducing Ligand (TRAIL) Levels in Patients with Bipolar Depression, Major Depression and a Healthy Control Group. Psychiatria Danubina. vol 33. issue 3. 2021-11-22. PMID:34795172. |
serum tnf- related weak inducer of apoptosis (tweak), tnf- related apoptosis-inducing ligand (trail) levels in patients with bipolar depression, major depression and a healthy control group. |
2021-11-22 |
2023-08-13 |
Not clear |
| Wing-Shan Yu, So-Hyun Kwon, Stephen Kugbere Agadagba, Leanne-Lai-Hang Chan, Kah-Hui Wong, Lee-Wei Li. Neuroprotective Effects and Therapeutic Potential of Transcorneal Electrical Stimulation for Depression. Cells. vol 10. issue 9. 2021-11-19. PMID:34572141. |
the beneficial effects of tes in depression were further supported by its shared mechanisms with fda-approved antidepressant treatments, including its neuroprotective properties against apoptosis and inflammation, and its ability to enhance the neurotrophic expression. |
2021-11-19 |
2023-08-13 |
Not clear |
| Bangkun Yang, Lesheng Wang, Ying Nie, Wei Wei, Wenping Xion. proBDNF expression induces apoptosis and inhibits synaptic regeneration by regulating the RhoA-JNK pathway in an in vitro post-stroke depression model. Translational psychiatry. vol 11. issue 1. 2021-11-17. PMID:34759285. |
probdnf expression induces apoptosis and inhibits synaptic regeneration by regulating the rhoa-jnk pathway in an in vitro post-stroke depression model. |
2021-11-17 |
2023-08-13 |
Not clear |
| Tiantian Han, Yingchun Zhou, Danhua L. Relationship between hepatocellular carcinoma and depression via online database analysis. Bioengineered. vol 12. issue 1. 2021-11-10. PMID:33960267. |
based on our findings, we hypothesize that the mechanism of the interaction between hcc and depression may be related to cell death or apoptosis. |
2021-11-10 |
2023-08-13 |
Not clear |
| Fang Jiang, Jun Lou, Xi-Ming Zheng, Xi-Yong Yan. LncRNA MIAT regulates autophagy and apoptosis of macrophage infected by Mycobacterium tuberculosis through the miR-665/ULK1 signaling axis. Molecular immunology. vol 139. 2021-11-05. PMID:34454184. |
mechanistically, the functional role of miat depletion in macrophage apoptosis and autophagy were tremendously abrogated by the depression of mir-665 and enrichment of ulk1. |
2021-11-05 |
2023-08-13 |
human |
| Chien-Ming Chu, Li-Chung Chiu, Chung-Chieh Yu, Li-Pang Chuang, Kuo-Chin Kao, Li-Fu Li, Huang-Pin W. Increased Death of Peripheral Blood Mononuclear Cells after TLR4 Inhibition in Sepsis Is Not via TNF/TNF Receptor-Mediated Apoptotic Pathway. Mediators of inflammation. vol 2021. 2021-11-05. PMID:34733114. |
apoptosis is one of the causes of immune depression in sepsis. |
2021-11-05 |
2023-08-13 |
Not clear |
| Jing-Mei Zhong, Shao-Yuan Wu, Jie Bai, Qiang Guo, Jian Tao, Hui Chen, Nai-Wei Zhao, Zhong Zhao, Hao F. Antidepressant effect of geranylgeranylacetone in a chronic mild stress model of depression and its possible mechanism. Experimental and therapeutic medicine. vol 4. issue 4. 2021-10-21. PMID:23170116. |
the activity of gga in the relief of depression may be mediated via the induction of hsp70 expression to suppress mao-a expression and the apoptosis cascade. |
2021-10-21 |
2023-08-12 |
rat |
| Brian E Leonar. The concept of depression as a dysfunction of the immune system. Current immunology reviews. vol 6. issue 3. 2021-10-20. PMID:21170282. |
in addition to the resulting decrease in the synthesis of brain serotonin, this leads to the formation of neurotoxins such as the glutamate agonist quinolinic acid and contributes to the increase in apoptosis of astrocytes, oligodendroglia and neurons.the importance of the inflammation hypothesis of depression lies in raising the possibility that psychotropic drugs that have a central anti-inflammatory action might provide a new generation of antidepressants. |
2021-10-20 |
2023-08-12 |
Not clear |
| Jian Liu, Lin Liu, Yuan-Shan Han, Jian Yi, Chun Guo, Hong-Qing Zhao, Jia Ling, Yu-Hong Wan. The molecular mechanism underlying mitophagy-mediated hippocampal neuron apoptosis in diabetes-related depression. Journal of cellular and molecular medicine. vol 25. issue 15. 2021-10-15. PMID:34213839. |
we hypothesized that diabetes-related depression might be associated with the mitophagy-mediated hippocampal neuron apoptosis, triggered by aberrant glu-glutamate receptor2 (glur2)-parkin pathway. |
2021-10-15 |
2023-08-13 |
rat |
| Jian Liu, Lin Liu, Yuan-Shan Han, Jian Yi, Chun Guo, Hong-Qing Zhao, Jia Ling, Yu-Hong Wan. The molecular mechanism underlying mitophagy-mediated hippocampal neuron apoptosis in diabetes-related depression. Journal of cellular and molecular medicine. vol 25. issue 15. 2021-10-15. PMID:34213839. |
the molecular mechanism underlying mitophagy-mediated hippocampal neuron apoptosis in diabetes-related depression. |
2021-10-15 |
2023-08-13 |
rat |
| Cleisson Schossler Garcia, Pabliane Rodrigues Garcia, Carlos Natã da Silva Espíndola, Gustavo D'Avila Nunes, Natália Silva Jardim, Sabrina Grendene Müller, Cristiani Folharini Bortolatto, César Augusto Brünin. Effect of m-Trifluoromethyl-diphenyl diselenide on the Pain-Depression Dyad Induced by Reserpine: Insights on Oxidative Stress, Apoptotic, and Glucocorticoid Receptor Modulation. Molecular neurobiology. vol 58. issue 10. 2021-10-08. PMID:34245440. |
evidence has demonstrated that neuronal oxidative stress, apoptosis, and also glucocorticoid receptor dysregulation facilitate the occurrence and development of both chronic pain and depression. |
2021-10-08 |
2023-08-13 |
Not clear |
| Gabriela César Falcão Vieira, Bruna Rachel de Oliveira Rodrigues, Carlos Eduardo Ximenes da Cunha, Gabriella Bento de Morais, Luiz Henrique Ribeiro de Moraes Ferreira, Marina Viegas Moura Rezende Ribeir. Depression and dry eye: a narrative review. Revista da Associacao Medica Brasileira (1992). vol 67. issue 3. 2021-09-03. PMID:34468615. |
also, the treatment of depression with selective inhibitors of serotonin receptors causes inflammatory cytokine secretion with subsequent inflammation and apoptosis of cells on the ocular surface. |
2021-09-03 |
2023-08-13 |
human |