| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Erica Costantini, Claudia Carrarini, Dario Calisi, Matteo De Rosa, Marianna Simone, Adolfo Di Crosta, Rocco Palumbo, Alessia Cipollone, Lisa Aielli, Maria De Laurentis, Lucilla Colarusso, Andrea Pilotto, Alessandro Padovani, Fani Konstantinidou, Valentina Gatta, Liborio Stuppia, Francesco Cipollone, Marta Di Nicola, Marcella Reale, Laura Bonann. Search in the Periphery for Potential Inflammatory Biomarkers of Dementia with Lewy Bodies and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2024-05-17. PMID:38759010. |
neuroinflammation, with altered peripheral proinflammatory cytokine production, plays a major role in the pathogenesis of neurodegenerative diseases, such as alzheimer's disease (ad), while the role of inflammation in dementia with lewy bodies (dlb) is less known and the results of different studies are often in disagreement. |
2024-05-17 |
2024-05-27 |
Not clear |
| Manon Querry, Anne Botzung, Benjamin Cretin, Catherine Demuynck, Candice Muller, Alix Ravier, Benoît Schorr, Mary Mondino, Léa Sanna, Paulo Loureiro de Sousa, Nathalie Philippi, Frédéric Blan. Neuroanatomical substrates of depression in dementia with Lewy bodies and Alzheimer's disease. GeroScience. 2024-05-15. PMID:38750385. |
dementia with lewy bodies (dlb) and alzheimer's disease (ad) are often associated with depressive symptoms from the prodromal stage. |
2024-05-15 |
2024-05-27 |
human |
| Cheri M Jrol. Dementia with Lewy bodies: Primary care PAs can make this difficult diagnosis. JAAPA : official journal of the American Academy of Physician Assistants. 2024-05-15. PMID:38747894. |
lewy body dementia is an umbrella term for dementia with lewy bodies (dlb) and parkinson disease dementia. |
2024-05-15 |
2024-05-27 |
Not clear |
| Kathryn A Wyman-Chick, Parichita Chaudhury, Ece Bayram, Carla Abdelnour, Elie Matar, Shannon Y Chiu, Daniel Ferreira, Calum A Hamilton, Paul C Donaghy, Federico Rodriguez-Porcel, Jon B Toledo, Annegret Habich, Matthew J Barrett, Bhavana Patel, Alberto Jaramillo-Jimenez, Gregory D Scott, Joseph P M Kan. Differentiating Prodromal Dementia with Lewy Bodies from Prodromal Alzheimer's Disease: A Pragmatic Review for Clinicians. Neurology and therapy. 2024-05-10. PMID:38720013. |
the core clinical features of dementia with lewy bodies (dlb)-parkinsonism, complex visual hallucinations, cognitive fluctuations, and rem sleep behaviour disorder are common prodromal symptoms. |
2024-05-10 |
2024-05-27 |
Not clear |
| Chiara Silvestri, Valentina Almici, Ilenia Libri, Irene Mattioli, Maura Cosseddu, Rosanna Turrone, Jasmine Rivolta, Chiara Grassini, Salvatore Caratozzolo, Antonella Alberici, Alessandra Marengoni, Andrea Pilotto, Barbara Borroni, Alessandro Padovani, Alberto Benuss. Sex Differences in the Severity and Progression of Neuropsychiatric Symptoms Across Different Dementia Types. Neurology. Clinical practice. vol 14. issue 3. 2024-05-10. PMID:38720954. |
dementia presents not only differing neuropsychiatric symptoms (nps) across alzheimer disease (ad), frontotemporal dementia (ftd), dementia with lewy bodies (dlb) but also subjective cognitive decline (scd). |
2024-05-10 |
2024-05-27 |
Not clear |
| Masatomo Kobayashi, Yasunori Yamada, Kaoru Shinkawa, Miyuki Nemoto, Miho Ota, Kiyotaka Nemoto, Tetsuaki Ara. Vocal expression of emotions discriminates dementia with Lewy bodies from Alzheimer's disease. Alzheimer's & dementia (Amsterdam, Netherlands). vol 16. issue 2. 2024-05-10. PMID:38721025. |
dementia with lewy bodies (dlb) and alzheimer's disease (ad), the two most common neurodegenerative dementias, both exhibit altered emotional processing. |
2024-05-10 |
2024-05-27 |
human |
| Janna van Wetering, Hanne Geut, John J Bol, Yvon Galis, Evelien Timmermans, Jos W R Twisk, Dagmar H Hepp, Martino L Morella, Lasse Pihlstrom, Afina W Lemstra, Annemieke J M Rozemuller, Laura E Jonkman, Wilma D J van de Ber. Neuroinflammation is associated with Alzheimer's disease co-pathology in dementia with Lewy bodies. Acta neuropathologica communications. vol 12. issue 1. 2024-05-08. PMID:38715119. |
neuroinflammation and alzheimer's disease (ad) co-pathology may contribute to disease progression and severity in dementia with lewy bodies (dlb). |
2024-05-08 |
2024-05-27 |
Not clear |
| Deirdre M O'Shea, Alexander Arkhipenko, Douglas Galasko, Jennifer G Goldman, Zulfiqar Haider Sheikh, George Petrides, Jon B Toledo, James E Galvi. Practical use of DAT SPECT imaging in diagnosing dementia with Lewy bodies: a US perspective of current guidelines and future directions. Frontiers in neurology. vol 15. 2024-05-08. PMID:38711561. |
diagnosing dementia with lewy bodies (dlb) remains a challenge in clinical practice. |
2024-05-08 |
2024-05-27 |
Not clear |
| N D Prins, W de Haan, A Gardner, K Blackburn, H-M Chu, J E Galvin, J J Ala. Phase 2A Learnings Incorporated into RewinD-LB, a Phase 2B Clinical Trial of Neflamapimod in Dementia with Lewy Bodies. The journal of prevention of Alzheimer's disease. vol 11. issue 3. 2024-05-06. PMID:38706271. |
in an exploratory 91-participant phase 2a clinical trial (ascend-lb, nct04001517) in dementia with lewy bodies (dlb), neflamapimod showed improvement over placebo on multiple clinical endpoints. |
2024-05-06 |
2024-05-08 |
Not clear |
| Apurva Bezalwar, Pradeep S Patil, Ishaan Gautam, Namita Sah. A Bird's-Eye Perspective: An Unusual Case of Very Late-Onset Schizophrenia-Like Psychosis With Visual Hallucinations Included in Its Manifestations Versus the Dementia Prodrome. Cureus. vol 16. issue 4. 2024-05-06. PMID:38707040. |
future research ought to emphasize identifying a particular biomarker that would be highly predictive for accurately diagnosing vloslp and giving it an identity to separate it from various overlapping clinical conditions such as dementia with lewy bodies (dlb) and other types of dementia with psychosis so that the patient can be given specific treatment. |
2024-05-06 |
2024-05-08 |
Not clear |
| Timothy S Chisholm, Ronald Melki, Christopher A Hunte. Ligand Profiling as a Diagnostic Tool to Differentiate Patient-Derived α-Synuclein Polymorphs. ACS chemical neuroscience. 2024-05-01. PMID:38690599. |
eight fibrillar polymorphs of α-synuclein (αsyn) were investigated: five generated de novo using recombinant αsyn and three generated using protein misfolding cyclic amplification (pmca) of recombinant αsyn seeded with brain homogenates from deceased patients diagnosed with parkinson's disease (pd), multiple system atrophy (msa), and dementia with lewy bodies (dlb). |
2024-05-01 |
2024-05-03 |
Not clear |
| Coralie Cressot, Agathe Vrillon, Matthieu Lilamand, Hélène Francisque, Aurélie Méauzoone, Claire Hourregue, Julien Dumurgier, Emeline Marlinge, Claire Paquet, Emmanuel Cogna. Psychosis in Neurodegenerative Dementias: A Systematic Comparative Review. Journal of Alzheimer's disease : JAD. 2024-04-26. PMID:38669539. |
psychosis, characterized by delusions and/or hallucinations, is frequently observed during the progression of alzheimer's disease (ad) and other neurodegenerative dementias (nd) (i.e., dementia with lewy bodies (dlb), and frontotemporal dementia (ftd)) and cause diagnostic and management difficulties. |
2024-04-26 |
2024-04-29 |
Not clear |
| Sungwoo Kang, Seun Jeon, Young-Gun Lee, Byoung Seok Y. Alteration of medial temporal lobe metabolism related to Alzheimer's disease and dementia with lewy bodies. Alzheimer's research & therapy. vol 16. issue 1. 2024-04-23. PMID:38654300. |
association of medial temporal lobe (mtl) metabolism with alzheimer's disease (ad) and dementia with lewy bodies (dlb) has not been evaluated considering their mixed disease (md). |
2024-04-23 |
2024-04-26 |
Not clear |
| Per Borghammer, Niels Okkels, Daniel Weintrau. Parkinson's Disease and Dementia with Lewy Bodies: One and the Same. Journal of Parkinson's disease. 2024-04-19. PMID:38640172. |
the question whether parkinson's disease dementia (pdd) and dementia with lewy bodies (dlb) are expressions of the same underlying disease has been vigorously debated for decades. |
2024-04-19 |
2024-04-22 |
Not clear |
| Alice Tisserand, Frédéric Blanc, Mary Mondino, Candice Muller, Hélène Durand, Catherine Demuynck, Paulo Loureiro de Sousa, Alix Ravier, Léa Sanna, Anne Botzung, Nathalie Philipp. Who am I with my Lewy bodies? The insula as a core region of the self-concept networks. Alzheimer's research & therapy. vol 16. issue 1. 2024-04-19. PMID:38641653. |
dementia with lewy bodies (dlb) is characterized by insular atrophy, which occurs at the early stage of the disease. |
2024-04-19 |
2024-04-22 |
Not clear |
| Melissa J Armstrong, Yunfeng Dai, Kaitlin Sovich, Brian LaBarre, Henry L Paulson, Susan M Maixner, Julie A Fields, Angela M Lunde, Leah K Forsberg, Bradley F Boeve, Carol A Manning, James E Galvin, Angela S Taylor, Zhigang L. Caregiver Experiences and Burden in Moderate-Advanced Dementia With Lewy Bodies. Neurology. Clinical practice. vol 14. issue 3. 2024-04-15. PMID:38617555. |
dementia with lewy bodies (dlb) is a common degenerative dementia, but research on caregiver experiences in late stages is lacking. |
2024-04-15 |
2024-04-17 |
Not clear |
| Michiyo Iba, Somin Kwon, Changyoun Kim, Marcell Szabo, Liam Horan-Portelance, Maria Lopez-Ocasio, Pradeep Dagur, Cassia Overk, Robert A Rissman, Eliezer Maslia. Immunotherapy with an antibody against CD1d modulates neuroinflammation in an α-synuclein transgenic model of Lewy body like disease. Journal of neuroinflammation. vol 21. issue 1. 2024-04-15. PMID:38622654. |
the neuroinflammatory process in synucleinopathies of the aging population such as parkinson's disease (pd) and dementia with lewy bodies (dlb) involves microglial activation as well as infiltration of the cns by t cells and natural killer t cells (nkts). |
2024-04-15 |
2024-04-18 |
mouse |
| Annegret Habich, Javier Oltra, Christopher G Schwarz, Scott A Przybelski, Ketil Oppedal, Anna Inguanzo, Frédéric Blanc, Afina W Lemstra, Jakub Hort, Eric Westman, Barbara Segura, Carme Junque, Val J Lowe, Bradley F Boeve, Dag Aarsland, Thomas Dierks, Kejal Kantarci, Daniel Ferreir. Grey matter networks in women and men with dementia with Lewy bodies. NPJ Parkinson's disease. vol 10. issue 1. 2024-04-13. PMID:38615089. |
sex differences permeate many aspects of dementia with lewy bodies (dlb), yet sex differences in patterns of neurodegeneration in dlb remain largely unexplored. |
2024-04-13 |
2024-04-16 |
Not clear |
| Alberto J Rico, Almudena Corcho, Julia Chocarro, Goiaz Ariznabarreta, Elvira Roda, Adriana Honrubia, Patricia Arnaiz, José L Lancieg. Development and characterization of a non-human primate model of disseminated synucleinopathy. Frontiers in neuroanatomy. vol 18. 2024-04-11. PMID:38601798. |
the presence of a widespread cortical synucleinopathy is the main neuropathological hallmark underlying clinical entities such as parkinson's disease with dementia (pdd) and dementia with lewy bodies (dlb). |
2024-04-11 |
2024-04-13 |
Not clear |
| Taku Hatano, Ayami Okuzumi, Gen Matsumoto, Tsunemi Taiji, Nobutaka Hattor. α-Synuclein: A Promising Biomarker for Parkinson's Disease and Related Disorders. Journal of movement disorders. 2024-04-08. PMID:38589016. |
rapid eye movement sleep behavior disorder (rbd) patients often progress to pd, dementia with lewy bodies (dlb), or msa, collectively known as α-synucleinopathies. |
2024-04-08 |
2024-04-11 |
Not clear |