| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| El Jeong, Yong Woo Shin, Jung-Ick Byun, Jun-Sang Sunwoo, Monica Roascio, Pietro Mattioli, Laura Giorgetti, Francesco Famà, Gabriele Arnulfo, Dario Arnaldi, Han-Joon Kim, Ki-Young Jun. EEG-based Machine Learning Models for the Prediction of Phenoconversion Time and Subtype in iRBD. Sleep. 2024-02-08. PMID:38330231. |
idiopathic/isolated rapid eye movement sleep behavior disorder (irbd) is a prodromal stage of α-synucleinopathies and eventually phenoconverts to overt neurodegenerative diseases including parkinson's disease (pd), dementia with lewy bodies (dlb) and multiple system atrophy (msa). |
2024-02-08 |
2024-02-11 |
Not clear |
| Ahmed A Elbatrawy, Taiwo A Ademoye, Heba Alnakhala, Arati Tripathi, Ashique Zami, Raluca Ostafe, Ulf Dettmer, Jessica S Forti. Discovery of small molecule benzothiazole and indole derivatives tackling tau 2N4R and α-synuclein fibrils. Bioorganic & medicinal chemistry. vol 100. 2024-02-08. PMID:38330847. |
on the other hand, misfolding of α-synuclein (α-syn) is the characteristic feature in pd and dementia with lewy bodies (dlb). |
2024-02-08 |
2024-02-11 |
Not clear |
| Anantharaman Shantaraman, Eric B Dammer, Obiadada Ugochukwu, Duc M Duong, Luming Yin, E Kathleen Carter, Marla Gearing, Alice Chen-Plotkin, Edward B Lee, John Q Trojanowski, David A Bennett, James J Lah, Allan I Levey, Nicholas T Seyfried, Lenora Higginbotha. Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease. bioRxiv : the preprint server for biology. 2024-02-08. PMID:38328211. |
lewy body dementia (lbd), a class of disorders comprising parkinson's disease dementia (pdd) and dementia with lewy bodies (dlb), features substantial clinical and pathological overlap with alzheimer's disease (ad). |
2024-02-08 |
2024-02-10 |
Not clear |
| Myung Jong Kim, Soojin Kim, Thomas Reinheckel, Dimitri Krain. Inhibition of cysteine protease cathepsin Lincreases the level and activity of lysosomal glucocerebrosidase. JCI insight. vol 9. issue 3. 2024-02-08. PMID:38329128. |
loss-of-function variants in the gba1 gene are also the most common genetic risk factor for parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2024-02-08 |
2024-02-10 |
mouse |
| Patricia Diaz-Galvan, Scott A Przybelski, Alicia Algeciras-Schimnich, Dan J Figdore, Timothy G Lesnick, Christopher G Schwarz, Matthew L Senjem, Jeffrey L Gunter, Clifford R Jack, Paul H Min, Manoj K Jain, Toji Miyagawa, Leah K Forsberg, Julie A Fields, Rodolfo Savica, Jonathan Graff-Radford, Vijay K Ramanan, David T Jones, Hugo Botha, Erik K St Louis, David S Knopman, Neill R Graff-Radford, Tanis J Ferman, Ronald C Petersen, Val J Lowe, Bradley F Boeve, Kejal Kantarc. Plasma biomarkers of Alzheimer's disease in the continuum of dementia with Lewy bodies. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-02-08. PMID:38329197. |
patients with dementia with lewy bodies (dlb) may have alzheimers disease (ad) pathology that can be detected by plasma biomarkers. |
2024-02-08 |
2024-02-10 |
Not clear |
| Ana Carreras Mascaro, Martyna M Grochowska, Valerie Boumeester, Natasja F J Dits, Ece Naz Bilgiҫ, Guido J Breedveld, Leonie Vergouw, Frank Jan de Jong, Martin E van Royen, Vincenzo Bonifati, Wim Mandemaker. LRP10 and α-synuclein transmission in Lewy body diseases. Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-02-05. PMID:38315424. |
autosomal dominant variants in lrp10 have been identified in patients with lewy body diseases (lbds), including parkinson's disease (pd), parkinson's disease-dementia (pdd), and dementia with lewy bodies (dlb). |
2024-02-05 |
2024-02-09 |
Not clear |
| Luca Sofia, Federico Massa, Matteo Pardini, Dario Arnaldi, Matteo Bauckneht, Silvia Morbell. Alzheimer's disease (AD) co-pathology in dementia with Lewy bodies (DLB): implications in the disease modification era. European journal of nuclear medicine and molecular imaging. 2024-01-29. PMID:38285205. |
alzheimer's disease (ad) co-pathology in dementia with lewy bodies (dlb): implications in the disease modification era. |
2024-01-29 |
2024-01-31 |
Not clear |
| Juan Huang, Xingxing Yuan, Lin Chen, Binbin Hu, Hui Wang, Ye Wang, Wei Huan. Pathological α-synuclein detected by real-time quaking-induced conversion in synucleinopathies. Experimental gerontology. 2024-01-27. PMID:38280659. |
the α-syn rt-quic assay has demonstrated good sensitivity and specificity in detecting pathological α-syn, particularly in parkinson's disease (pd) and dementia with lewy bodies (dlb) cases, with an accuracy rate of up to 80 %. |
2024-01-27 |
2024-01-30 |
Not clear |
| Melissa J Armstrong, Lisa L Barne. Under-Diagnosis of Dementia with Lewy Bodies in Individuals Racialized as Black: Hypotheses Regarding Potential Contributors. Journal of Alzheimer's disease : JAD. 2024-01-26. PMID:38277299. |
dementia with lewy bodies (dlb) is one of the most common degenerative dementias after alzheimer's disease (ad) dementia. |
2024-01-26 |
2024-01-29 |
Not clear |
| Émile Cogné, Ronald B Postuma, Marie-Joëlle Chasles, Jessie De Roy, Jacques Montplaisir, Amélie Pelletier, Isabelle Rouleau, Jean-François Gagno. Montreal Cognitive Assessment and the Clock Drawing Test to Identify MCI and Predict Dementia in Isolated REM Sleep Behavior Disorder. Neurology. vol 102. issue 4. 2024-01-25. PMID:38271662. |
patients with isolated/idiopathic rem sleep behavior disorder (irbd) are at high risk for developing mild cognitive impairment (mci) and dementia with lewy bodies (dlb). |
2024-01-25 |
2024-01-28 |
Not clear |
| Antonio Longobardi, Marcella Catania, Andrea Geviti, Erika Salvi, Elena Rita Vecchi, Sonia Bellini, Claudia Saraceno, Roland Nicsanu, Rosanna Squitti, Giuliano Binetti, Giuseppe Di Fede, Roberta Ghidon. Autophagy Markers Are Altered in Alzheimer's Disease, Dementia with Lewy Bodies and Frontotemporal Dementia. International journal of molecular sciences. vol 25. issue 2. 2024-01-23. PMID:38256197. |
the accumulation of protein aggregates defines distinct, yet overlapping pathologies such as alzheimer's disease (ad), dementia with lewy bodies (dlb), and frontotemporal dementia (ftd). |
2024-01-23 |
2024-01-25 |
human |
| Motoko Watanabe, Wataru Araki, Chihiro Takao, Chizuko Maeda, Risa Tominaga, Yasuyuki Kimura, Gayatri Nayanar, Trang Thi Huyen Tu, Takashi Asada, Akira Toyofuk. A case with burning mouth syndrome followed by dementia with Lewy bodies: a case report. Frontiers in psychiatry. vol 14. 2024-01-23. PMID:38260804. |
dementia with lewy bodies (dlb) is a common type of dementia and generally presents visual hallucination and parkinsonism as motor dysfunction besides cognitive decline. |
2024-01-23 |
2024-01-25 |
Not clear |
| Motoko Watanabe, Wataru Araki, Chihiro Takao, Chizuko Maeda, Risa Tominaga, Yasuyuki Kimura, Gayatri Nayanar, Trang Thi Huyen Tu, Takashi Asada, Akira Toyofuk. A case with burning mouth syndrome followed by dementia with Lewy bodies: a case report. Frontiers in psychiatry. vol 14. 2024-01-23. PMID:38260804. |
her cognitive impairment and disorientation were also reported by her husband on the day 572, she was then immediately referred to a neurologist specialized dementia and diagnosed with dlb on the day 583. |
2024-01-23 |
2024-01-25 |
Not clear |
| Tiffany Jong, Alexandra Gehrlein, Ellen Sidransky, Ravi Jagasia, Yu Che. Characterization of Novel Human β-glucocerebrosidase Antibodies for Parkinson's Disease Research. Journal of Parkinson's disease. 2024-01-22. PMID:38251062. |
mutations in gba1, which encodes the lysosome enzyme β-glucocerebrosidase (also referred to as acid β-glucosidase or gcase), are the most common genetic risk factor for parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2024-01-22 |
2024-01-24 |
human |
| Adeel A Memon, Ethan B George, Talha Nazir, Yatharth Sunkara, Corina Catiul, Amy W Amar. Heart rate variability during sleep in synucleinopathies: a review. Frontiers in neurology. vol 14. 2024-01-19. PMID:38239321. |
these consist of parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa). |
2024-01-19 |
2024-01-21 |
Not clear |
| Xiaobei Pan, Paul C Donaghy, Gemma Roberts, Leonidas Chouliaras, John T O'Brien, Alan J Thomas, Amanda J Heslegrave, Henrik Zetterberg, Bernadette McGuinness, Anthony P Passmore, Brian D Green, Joseph P M Kan. Plasma metabolites distinguish dementia with Lewy bodies from Alzheimer's disease: a cross-sectional metabolomic analysis. Frontiers in aging neuroscience. vol 15. 2024-01-19. PMID:38239488. |
this study aimed to profile the plasma metabolome of patients with dementia with lewy bodies (dlb) and alzheimer's disease (ad), two neurodegenerative disorders for which our understanding of the pathophysiology is incomplete. |
2024-01-19 |
2024-01-21 |
Not clear |
| Denise Cerne, Mattia Losa, Pietro Mattioli, Anastasia Lechiara, Giacomo Rebella, Luca Roccatagliata, Dario Arnaldi, Angelo Schenone, Silvia Morbelli, Luana Benedetti, Federico Mass. Incident anti-LGI1 autoimmune encephalitis during dementia with Lewy bodies: when Occam razor is a double-edged sword. Journal of neuroimmunology. vol 387. 2024-01-18. PMID:38237526. |
in dementia with lewy bodies (dlb), rapid cognitive decline and seizures seldom complicate the typical clinical course. |
2024-01-18 |
2024-01-21 |
Not clear |
| Ryota Kobayashi, Daichi Morioka, Shinobu Kawakatsu, Kazutaka Sakamoto, Akihito Suzuk. Application of Suggestive Biomarkers in Dementia With Lewy Bodies With Masking of Typical Clinical Symptoms by Alzheimer Disease-type Pathology. Alzheimer disease and associated disorders. 2024-01-16. PMID:38227857. |
dementia with lewy bodies (dlb) is strongly associated with alzheimer disease (ad)-type pathology and tends to mask the core clinical features of dlb. |
2024-01-16 |
2024-01-19 |
Not clear |
| Ryota Kobayashi, Daichi Morioka, Shinobu Kawakatsu, Kazutaka Sakamoto, Akihito Suzuk. Application of Suggestive Biomarkers in Dementia With Lewy Bodies With Masking of Typical Clinical Symptoms by Alzheimer Disease-type Pathology. Alzheimer disease and associated disorders. 2024-01-16. PMID:38227857. |
however, the application of biomarkers suggestive of dlb to all patients with dementia is not realistic. |
2024-01-16 |
2024-01-19 |
Not clear |
| Tiphaine Monvoisin-Joly, Emmanuelle Furcieri, Elena Chabran, Mary Mondino, Paulo Loureiro de Sousa, Anne Botzung, Blanc Frédéri. Neural basis of writing in prodromal to mild dementia with lewy bodies. International journal of geriatric psychiatry. vol 39. issue 1. 2024-01-16. PMID:38229210. |
we have previously demonstrated difficulties in written production in dementia with lewy bodies (dlb) patients. |
2024-01-16 |
2024-01-19 |
Not clear |