| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Luiza Jadwiga Chwiszczuk, Monica Haraldseid Breitve, Bjørn-Eivind Bordewick Kirsebom, Per Selnes, John Chr Fløvig, Anne-Brita Knapskog, Ragnhild E Skogseth, Jessica Hubbers, Elin Holst-Larsen, Arvid Rongv. The ANeED study - ambroxol in new and early dementia with Lewy bodies (DLB): protocol for a phase IIa multicentre, randomised, double-blinded and placebo-controlled trial. Frontiers in aging neuroscience. vol 15. 2023-06-12. PMID:37304077. |
currently, there are no disease-modifying pharmacological treatment options for dementia with lewy bodies (dlb). |
2023-06-12 |
2023-08-14 |
Not clear |
| Kurt A Jellinge. Morphological characteristics differentiate dementia with Lewy bodies from Parkinson disease with and without dementia. Journal of neural transmission (Vienna, Austria : 1996). 2023-06-12. PMID:37306790. |
dementia with lewy bodies (dlb) and parkinson disease (pd) with and without dementia are entities of a spectrum of lewy body diseases. |
2023-06-12 |
2023-08-14 |
Not clear |
| Kurt A Jellinge. Morphological characteristics differentiate dementia with Lewy bodies from Parkinson disease with and without dementia. Journal of neural transmission (Vienna, Austria : 1996). 2023-06-12. PMID:37306790. |
190 of them had clinical dementia; 110 met the neuropathological criteria of pdd and 80 of dlb. |
2023-06-12 |
2023-08-14 |
Not clear |
| Young-Gun Lee, Seun Jeon, Kyoungwon Baik, Sung Woo Kang, Byoung Seok Y. Substantia nigral dopamine transporter uptake in dementia with Lewy bodies. NPJ Parkinson's disease. vol 9. issue 1. 2023-06-11. PMID:37296236. |
nigrostriatal dopaminergic degeneration is a pathological hallmark of dementia with lewy bodies (dlb). |
2023-06-11 |
2023-08-14 |
Not clear |
| Linjuan Feng, Hsuan Lo, Zhaoxiang Hong, Jiahao Zheng, Yuhong Yan, Zucheng Ye, Xiaochun Chen, Xiaodong Pa. Microglial LRRK2-mediated NFATc1 attenuates α-synuclein immunotoxicity in association with CX3CR1-induced migration and the lysosome-initiated degradation. Glia. 2023-06-10. PMID:37300531. |
synucleinopathies refer to a range of neurodegenerative diseases caused by abnormal α-synuclein (α-syn) deposition, including parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa). |
2023-06-10 |
2023-08-14 |
mouse |
| János Bencze, Woosung Seo, Abdul Hye, Dag Aarsland, Tibor Hortobágy. Dementia with Lewy bodies - a clinicopathological update. Free neuropathology. vol 1. 2023-06-07. PMID:37283665. |
although alzheimer's disease (ad), as the most frequent neurodegenerative dementia, has been extensively analysed, less is known about dementia with lewy bodies (dlb). |
2023-06-07 |
2023-08-14 |
Not clear |
| Sharad Kumar Suthar, Sang-Yoon Le. Truncation or proteolysis of α-synuclein in Parkinsonism. Ageing research reviews. 2023-06-07. PMID:37286088. |
posttranslational modifications of α-synuclein, such as truncation or abnormal proteolysis, are implicated in parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa). |
2023-06-07 |
2023-08-14 |
Not clear |
| Seiji Yuuki, Mamoru Hashimoto, Asuka Koyama, Masateru Matsushita, Tomohisa Ishikawa, Ryuji Fukuhara, Kazuki Honda, Yusuke Miyagawa, Manabu Ikeda, Minoru Takebayash. Comparison of caregiver burden between dementia with Lewy bodies and Alzheimer's disease. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. 2023-06-04. PMID:37271219. |
caring for patients with dementia with lewy bodies (dlb) would be more stressful for their caregivers than those with alzheimer's disease (ad). |
2023-06-04 |
2023-08-14 |
Not clear |
| Fabricio Ferreira de Oliveira, Marjorie Câmara Miraldo, Eduardo Ferreira de Castro-Neto, Sandro Soares de Almeida, Sandro Luiz de Andrade Matas, Paulo Henrique Ferreira Bertolucci, Maria da Graça Naffah-Mazzacoratt. Differential associations of clinical features with cerebrospinal fluid biomarkers in dementia with Lewy bodies and Alzheimer's disease. Aging clinical and experimental research. 2023-06-01. PMID:37264166. |
to explore associations of cerebrospinal fluid biomarkers of neurodegeneration and amyloidosis with caregiver burden, cognition and functionality in dementia with lewy bodies (dlb) paired with late-onset alzheimer's disease (ad) and healthy older people. |
2023-06-01 |
2023-08-14 |
Not clear |
| Camilla Christina Pedersen, Anastasia Ushakova, Ragnhild Eide Skogseth, Guido Alves, Ole-Bjørn Tysnes, Dag Aarsland, Johannes Lange, Jodi Maple-Grøde. Inflammatory Biomarkers in Newly Diagnosed Patients With Parkinson Disease and Related Neurodegenerative Disorders. Neurology(R) neuroimmunology & neuroinflammation. vol 10. issue 4. 2023-05-31. PMID:37258413. |
neuroinflammation also plays a role in related neurodegenerative diseases, such as dementia with lewy bodies (dlb) and alzheimer disease (ad). |
2023-05-31 |
2023-08-14 |
Not clear |
| Vinod Metta, Guy Chung-Faye, Hani Ts Benamer, Rukmini Mrudula, Vinay Goyal, Cristian Falup-Pecurariu, Neha Muralidharan, Desh Deepak, Mohammed Abdulraheem, Rupam Borgohain, Kallol Ray Chaudhur. Hiccups, Hypersalivation, Hallucinations in Parkinson's Disease: New Insights, Mechanisms, Pathophysiology, and Management. Journal of personalized medicine. vol 13. issue 5. 2023-05-27. PMID:37240881. |
hallucinations, especially visual hallucinations, are commonly reported, with a prevalence of 32-63% in pd, and a 55-78% prevalence is noted in patients with dementia with lewy bodies (dlb), followed by tactile hallucinations, which are indicated by a sensation of crawling bugs or imaginary creatures across the skin surface. |
2023-05-27 |
2023-08-14 |
Not clear |
| Tatyana Dmitrievna Fedorova, Karoline Knudsen, Jacob Horsager, Allan K Hansen, Niels Okkels, Hanne Gottrup, Kim Vang, Per Borghamme. Dopaminergic Dysfunction Is More Symmetric in Dementia with Lewy Bodies Compared to Parkinson's Disease. Journal of Parkinson's disease. 2023-05-22. PMID:37212074. |
we have hypothesized that most patients with dementia with lewy bodies (dlb) belong to the body-first subtype, whereas patients with parkinson's disease (pd) more often belong to the brain-first subtype. |
2023-05-22 |
2023-08-14 |
Not clear |
| Manon Querry, Frédéric Blanc, Olivier Bousiges, Nathalie Philippi, Benjamin Cretin, Catherine Demuynck, Candice Muller, Anne Botzun. Memory Outcome in Prodromal and Mild Dementia with Lewy Bodies and Alzheimer's Disease: A Longitudinal Study. Journal of Alzheimer's disease : JAD. 2023-05-22. PMID:37212104. |
dementia with lewy bodies (dlb) and alzheimer's disease (ad) are likely to induce memory impairments from the prodromal stage but, to our knowledge, no longitudinal study of these patients' memory profile has been conducted to date. |
2023-05-22 |
2023-08-14 |
Not clear |
| Jung Hwan Shin, Heejung Kim, Yu Kyeong Kim, Eun Jin Yoon, Hyunwoo Nam, Beomseok Jeon, Jee-Young Le. Longitudinal evolution of cortical thickness signature reflecting Lewy body dementia in isolated REM sleep behavior disorder: a prospective cohort study. Translational neurodegeneration. vol 12. issue 1. 2023-05-22. PMID:37217951. |
the isolated rapid-eye-movement sleep behavior disorder (irbd) is a prodromal condition of lewy body disease including parkinson's disease and dementia with lewy bodies (dlb). |
2023-05-22 |
2023-08-14 |
Not clear |
| Giulia Remoli, Leonardo Tariciotti, Luigi Gianmaria Remore, Paolo Palmisciano, Francesco Sciancalepore, Marco Canevelli, Eleonora Lacorte, Fulvio Da Re, Giuseppe Bruno, Carlo Ferrarese, Ildebrando Appollonio, Marco Locatelli, Nicola Vanacor. An updated overview of recent and ongoing deep brain stimulation (DBS) trials in patients with dementia: a systematic review. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2023-05-19. PMID:37204563. |
several technologies have been developed to slow cognitive decline: deep brain stimulation (dbs) of network targets in alzheimer's disease (ad) and dementia with lewy bodies (dlb) have been recently investigated. |
2023-05-19 |
2023-08-14 |
Not clear |
| Patricia Diaz-Galvan, Scott A Przybelski, Timothy G Lesnick, Christopher G Schwarz, Matthew L Senjem, Jeffrey L Gunter, Clifford R Jack, Hoon-Ki Paul Min, Manoj Jain, Toji Miyagawa, Leah K Forsberg, Julie A Fields, Rodolfo Savica, Jonathan Graff-Radford, David T Jones, Hugo Botha, Erik K St Louis, David S Knopman, Vijay K Ramanan, Owen Ross, Neill Graff-Radford, Gregory S Day, Dennis W Dickson, Tanis J Ferman, Ronald C Petersen, Val J Lowe, Brad F Boeve, Kejal Kantarc. β-Amyloid Load on PET Along the Continuum of Dementia With Lewy Bodies. Neurology. 2023-05-18. PMID:37202168. |
amyloid-β plaques can co-occur with lewy-related pathology in patients with dementia with lewy bodies (dlb), but amyloid-β load at prodromal stages of dlb still needs to be elucidated. |
2023-05-18 |
2023-08-14 |
Not clear |
| Feyza Mutlay, Derya Kaya, Esra Ates Bulut, Burcu Akpınar Söylemez, Mehmet Selman Öntan, Ahmet Turan Isı. Validation of the Turkish version of the Lewy body composite risk score. Applied neuropsychology. Adult. 2023-05-15. PMID:37183974. |
we aimed to assess the validity and reliability of the turkish version of the lbcrs in patients with dementia with lewy bodies (dlb) and investigate the discriminative power of the test in turkish patients with alzheimer's disease (ad) and dlb, and control group. |
2023-05-15 |
2023-08-14 |
Not clear |
| Youngsoon Yang, Eva Bagyinszky, Seong Soo A A. Presenilin-1 (PSEN1) Mutations: Clinical Phenotypes beyond Alzheimer's Disease. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37176125. |
in addition to the classical early onset alzheimer's disease (eoad) phenotypes, psen1 mutations were discovered in several atypical ad or non-ad phenotypes, such as frontotemporal dementia (ftd), parkinson's disease (pd), dementia with lewy bodies (dlb) or spastic paraparesis (sp). |
2023-05-14 |
2023-08-14 |
Not clear |
| Cheryl E G Leyns, Alice Prigent, Brenna Beezhold, Lihang Yao, Nathan G Hatcher, Peining Tao, John Kang, EunRan Suh, Vivianna M Van Deerlin, John Q Trojanowski, Virginia M Y Lee, Matthew E Kennedy, Matthew J Fell, Michael X Henderso. Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinson's disease. NPJ Parkinson's disease. vol 9. issue 1. 2023-05-11. PMID:37169750. |
parkinson's disease (pd) and dementia with lewy bodies (dlb) are progressive neurodegenerative diseases characterized by the accumulation of misfolded α-synuclein in the form of lewy pathology. |
2023-05-11 |
2023-08-14 |
Not clear |
| Michiyo Iba, Changyoun Kim, Somin Kwon, Marcell Szabo, Liam Horan-Portelance, Cody J Peer, William D Figg, Xylena Reed, Jinhui Ding, Seung-Jae Lee, Robert A Rissman, Mark R Cookson, Cassia Overk, Wolf Wrasidlo, Eliezer Maslia. Inhibition of p38α MAPK restores neuronal p38γ MAPK and ameliorates synaptic degeneration in a mouse model of DLB/PD. Science translational medicine. vol 15. issue 695. 2023-05-10. PMID:37163617. |
alterations in the p38 mitogen-activated protein kinases (mapks) play an important role in the pathogenesis of dementia with lewy bodies (dlb) and parkinson's disease (pd). |
2023-05-10 |
2023-08-14 |
mouse |