| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chuanqi Sun, Kang Zhou, Peter DePaola, WooShik Shin, Trae Hillyer, MichaelR Sawaya, Ruowei Zhu, Chao Peng, Z Hong Zhou, Lin Jian. Cryo-EM structure of amyloid fibril formed by α-synuclein hereditary A53E mutation reveals a distinct protofilament interface. The Journal of biological chemistry. 2023-03-05. PMID:36871760. |
synucleinopathies like parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple systems atrophy (msa), have the same pathologic feature of misfolded α-synuclein protein (α-syn) accumulation in the brain. |
2023-03-05 |
2023-08-14 |
Not clear |
| Ahmet Turan Isik, Fatma Sena Dost, Idil Yavuz, Mehmet Selman Ontan, Esra Ates Bulut, Derya Kay. Orthostatic hypotension in dementia with Lewy bodies: a meta-analysis of prospective studies. Clinical autonomic research : official journal of the Clinical Autonomic Research Society. 2023-03-02. PMID:36862320. |
orthostatic hypotension (oh), one of the supportive clinical features in the diagnosis of dementia with lewy bodies (dlb), is a significant problem in advanced age because of its severe negative consequences. |
2023-03-02 |
2023-08-14 |
Not clear |
| Ohnmar Hsam, Zacharias Koh. Serotonin in Synucleinopathies. Behavioural brain research. 2023-03-02. PMID:36863462. |
dysfunction of the serotonergic system represents an important feature in synucleinopathies like parkinson disease (pd), dementia with lewy bodies (dlb) and multiple system atrophy (msa). |
2023-03-02 |
2023-08-14 |
Not clear |
| Niels Hansen, Caroline Bouter, Sebastian Johannes Müller, Christoph van Riesen, Eya Khadhraoui, Marielle Ernst, Christian Heiner Riedel, Jens Wiltfang, Claudia Lang. New Insights into Potential Biomarkers in Patients with Mild Cognitive Impairment Occurring in the Prodromal Stage of Dementia with Lewy Bodies. Brain sciences. vol 13. issue 2. 2023-02-25. PMID:36831785. |
prodromal dementia with lewy bodies (dlb) can emerge with the onset of mild cognitive impairment (mci). |
2023-02-25 |
2023-08-14 |
Not clear |
| Cecilia Boccalini, Nicolas Nicastro, Debora Elisa Peretti, Silvia Paola Caminiti, Daniela Perani, Valentina Garibott. Sex differences in dementia with Lewy bodies: an imaging study of neurotransmission pathways. European journal of nuclear medicine and molecular imaging. 2023-02-24. PMID:36826477. |
dementia with lewy bodies (dlb) is characterized by a wide clinical and biological heterogeneity, with sex differences reported in both clinical and pathologically confirmed dlb cohorts. |
2023-02-24 |
2023-08-14 |
Not clear |
| Monica Hepker, Griffin Clabaugh, Huajun Jin, Anumantha G Kanthasam. New protocol for kinetic assay seeding ability recovery "KASAR" from formalin-fixed paraffin-embedded tissues. Frontiers in molecular biosciences. vol 10. 2023-02-16. PMID:36793788. |
initially, samples from seven human brain samples, including four samples from patients diagnosed with dementia with lewy bodies (dlb) and three samples from healthy controls without dlb, were compared to fresh frozen samples under three different, but clinically common sample storage conditions: formalin-fixed, ffpe, and ffpe slices cut 5 µm thick. |
2023-02-16 |
2023-08-14 |
human |
| Gang Chen, Shuai Liu, Hao Wu, Jinghuan Gan, Xiaodan Wang, Yong J. Analysis of clinical characteristics of mirror and TV signs in Alzheimer's disease and dementia with Lewy bodies. The Journal of international medical research. vol 51. issue 2. 2023-02-16. PMID:36794570. |
this study explored the clinical features of dementia with lewy bodies (dlb) and alzheimer's disease (ad) and analyzed the differences in neurologic syndromes, including mirror and tv signs, between different groups. |
2023-02-16 |
2023-08-14 |
Not clear |
| Stefano L Sensi, Mirella Russo, Pietro Tirabosch. Biomarkers of diagnosis, prognosis, pathogenesis, response to therapy: Convergence or divergence? Lessons from Alzheimer's disease and synucleinopathies. Handbook of clinical neurology. vol 192. 2023-02-16. PMID:36796942. |
the soluble to insoluble conversion also affects other normal brain proteins, such as tdp-43 and tau, accumulating in their insoluble states in both ad and dementia with lewy bodies (dlb). |
2023-02-16 |
2023-08-14 |
Not clear |
| Carolyn W Zhu, Yian Gu, Anton J Kociolek, Kayri K Fernandez, Stephanie Cosentino, Yaakov Ster. Costs During the Last Five Years of Life for Patients with Clinical and Pathological Confirmed Diagnosis of Lewy Body Dementia and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2023-02-13. PMID:36776064. |
little is known regarding healthcare expenditures for patients with dementia with lewy bodies (dlb) during the end of life. |
2023-02-13 |
2023-08-14 |
Not clear |
| Annegret Habich, Javier Oltra, Christopher G Schwarz, Scott A Przybelski, Ketil Oppedal, Anna Inguanzo, Frédéric Blanc, Afina W Lemstra, Jakub Hort, Eric Westman, Val J Lowe, Bradley F Boeve, Thomas Dierks, Dag Aarsland, Kejal Kantarci, Daniel Ferreir. Sex differences in grey matter networks in dementia with Lewy bodies. Research square. 2023-02-13. PMID:36778448. |
objectives sex differences permeate many aspects of dementia with lewy bodies (dlb), including epidemiology, pathogenesis, disease progression, and symptom manifestation. |
2023-02-13 |
2023-08-14 |
Not clear |
| Zuzanna Granek, Julia Barczuk, Natalia Siwecka, Wioletta Rozpędek-Kamińska, Ewa Kucharska, Ireneusz Majstere. International journal of molecular sciences. vol 24. issue 3. 2023-02-11. PMID:36768367. |
the most prevalent α-synucleinopathies are parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa). |
2023-02-11 |
2023-08-14 |
Not clear |
| Javier Oltra, Annegret Habich, Christopher G Schwarz, Zuzana Nedelska, Scott A Przybelski, Anna Inguanzo, Patricia Diaz-Galvan, Val J Lowe, Ketil Oppedal, Frederic Blanc, Afina W Lemstra, Jakub Hort, Alessandro Padovani, Irena Rektorova, Laura Bonanni, Federico Massa, Milica G Kramberger, John-Paul Taylor, Jon Snædal, Zuzana Walker, Angelo Antonini, Barbara Segura, Carme Junque, Eric Westman, Bradley F Boeve, Dag Aarsland, Kejal Kantarci, Daniel Ferreir. Sex differences in brain atrophy in dementia with Lewy bodies. Research square. 2023-02-07. PMID:36747755. |
however, little is known about the contribution of sex differences to the neurodegeneration in dementia with lewy bodies (dlb). |
2023-02-07 |
2023-08-14 |
Not clear |
| Aloke K Dutta, Christopher Armstrong, Dan Luo, Banibrata Das, Brian Spencer, Robert A Rissma. ACS chemical neuroscience. 2023-02-07. PMID:36749600. |
these clinically distinct disorders are known as pure autonomic failure, parkinson's disease (pd), parkinson's disease dementia (pdd), dementia with lewy bodies (dlb), and multiple system atrophy (msa). |
2023-02-07 |
2023-08-14 |
Not clear |
| Silvia Paola Caminiti, Andrea Pilotto, Enrico Premi, Alice Galli, Elisabetta Ferrari, Stefano Gipponi, Elisabetta Cottini, Barbara Paghera, Daniela Perani, Alessandro Padovan. Dopaminergic connectivity reconfiguration in the dementia with Lewy bodies continuum. Parkinsonism & related disorders. vol 108. 2023-02-01. PMID:36724569. |
the impairment of nigrostriatal dopaminergic network is a core feature of dementia with lewy bodies (dlb). |
2023-02-01 |
2023-08-14 |
Not clear |
| Suzhen Lin, André D G Leitão, Savannah Fang, Yingli Gu, Sophia Barber, Rhiannon Gilliard-Telefoni, Alfredo Castro, Kijung Sung, Ruinan Shen, Jazmin B Florio, Michael L Mante, Jianqing Ding, Brian Spencer, Eliezer Masliah, Robert A Rissman, Chengbiao W. Overexpression of alpha synuclein disrupts APP and Endolysosomal axonal trafficking in a mouse model of synucleinopathy. Neurobiology of disease. 2023-01-26. PMID:36702318. |
mutations or triplication of the alpha synuclein (asyn) gene contribute to synucleinopathies including parkinson's disease (pd), dementia with lewy bodies (dlb) and multiple system atrophy (msa). |
2023-01-26 |
2023-08-14 |
mouse |
| Sana Ando, Masashi Sakurai, Shusaku Shibutani, Nobuyuki Kimura, Nobuhiro Shimozawa, Yasuhiro Yasutomi, Ryotaro Yabe, Takashi Ohama, Koichi Sat. Age-related alterations in protein phosphatase 2A methylation levels in brains of cynomolgus monkeys: a pilot study. Journal of biochemistry. 2023-01-26. PMID:36702627. |
the abnormal activity of pp2a, a dominant member of type 2a serine/threonine protein phosphatase, has been implicated in the development of alzheimer's disease (ad) and dementia with lewy bodies (dlb). |
2023-01-26 |
2023-08-14 |
monkey |
| Shannon Y Chiu, Kathryn A Wyman-Chick, Tanis J Ferman, Ece Bayram, Samantha K Holden, Parichita Choudhury, Melissa J Armstron. Sex differences in dementia with Lewy bodies: Focused review of available evidence and future directions. Parkinsonism & related disorders. 2023-01-22. PMID:36682958. |
in this review, we summarize the current knowledge on sex differences in dementia with lewy bodies (dlb) relating to epidemiology, clinical features, neuropathology, biomarkers, disease progression, and caregiving. |
2023-01-22 |
2023-08-14 |
Not clear |
| Anna Inguanzo, Konstantinos Poulakis, Rosaleena Mohanty, Christopher G Schwarz, Scott A Przybelski, Patricia Diaz-Galvan, Val J Lowe, Bradley F Boeve, Afina W Lemstra, Marleen van de Beek, Wiesje van der Flier, Frederik Barkhof, Frederic Blanc, Paulo Loureiro de Sousa, Nathalie Philippi, Benjamin Cretin, Catherine Demuynck, Zuzana Nedelska, Jakub Hort, Barbara Segura, Carme Junque, Ketil Oppedal, Dag Aarsland, Eric Westman, Kejal Kantarci, Daniel Ferreir. MRI data-driven clustering reveals different subtypes of Dementia with Lewy bodies. NPJ Parkinson's disease. vol 9. issue 1. 2023-01-20. PMID:36670121. |
dementia with lewy bodies (dlb) is a neurodegenerative disorder with a wide heterogeneity of symptoms, which suggests the existence of different subtypes. |
2023-01-20 |
2023-08-14 |
Not clear |
| Irene Frigerio, Max A Laansma, Chen-Pei Lin, Emma J M Hermans, Maud M A Bouwman, John G J M Bol, Yvon Galis-de Graaf, Dagmar H Hepp, Annemieke J M Rozemuller, Frederik Barkhof, Wilma D J van de Berg, Laura E Jonkma. Neurofilament light chain is increased in the parahippocampal cortex and associates with pathological hallmarks in Parkinson's disease dementia. Translational neurodegeneration. vol 12. issue 1. 2023-01-19. PMID:36658627. |
in this study, we aimed to investigate the distribution of neurofilaments in the cerebral cortex of parkinson's disease (pd), pd with dementia (pdd) and dementia with lewy bodies (dlb) donors, and its association with pathology load and mri measures of atrophy and diffusivity. |
2023-01-19 |
2023-08-14 |
Not clear |
| E Costantini, C Carrarini, P Borrelli, M De Rosa, D Calisi, S Consoli, D D'Ardes, F Cipollone, M Di Nicola, M Onofrj, M Reale, L Bonann. Different peripheral expression patterns of the nicotinic acetylcholine receptor in dementia with Lewy bodies and Alzheimer's disease. Immunity & ageing : I & A. vol 20. issue 1. 2023-01-16. PMID:36647139. |
indeed, the deregulated function of the nachr was previously correlated with cognitive decline and neuropsychiatric symptoms in alzheimer's disease (ad) and dementia with lewy bodies (dlb). |
2023-01-16 |
2023-08-14 |
Not clear |