| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emanuele Camerucci, Aidan F Mullan, Pierpaolo Turcano, Cole D Stang, James Bower, Eduardo E Benarroch, Bradley F Boeve, Rodolfo Savic. A Population-Based Approach to the Argument on Brain-First and Body-First Pathogenesis of Lewy Body Disease. Annals of neurology. 2024-06-11. PMID:38860478. |
to explore the clinical progression of the brain-/body-first categories within lewy body disease (lbd): parkinson's disease (pd), dementia with lewy bodies (dlb), and pd dementia. |
2024-06-11 |
2024-06-14 |
Not clear |
| Tianyu Zheng, David Kotol, Rebecca Sjöberg, Nicholas Mitsios, Mathias Uhlén, Wen Zhong, Fredrik Edfors, Jan Mulde. Characterization of reduced astrocyte creatine kinase levels in Alzheimer's disease. Glia. 2024-06-10. PMID:38856187. |
in our study, cerebral cortex samples from individuals with ad, dementia with lewy bodies (dlb), and age-matched controls were analyzed using antibody-based methods to quantify ckb levels and assess alterations associated with disease processes. |
2024-06-10 |
2024-06-14 |
human |
| Gaku Honda, Shigeki Nagamachi, Mai Takahashi, Yukie Higuma, Tomonobu Tani, Kosuke Hida, Kengo Yoshimitsu, Koji Ogomori, Yoshio Tsubo. The usefulness of combined analysis using CIScore and VSRAD parameters for differentiating between dementia with Lewy body and Alzheimer's disease. Japanese journal of radiology. 2024-06-10. PMID:38856880. |
the cingulate island score (ciscore) is useful index for differentiating between dementia with lewy body (dlb) and alzheimer's disease (ad) using regional cerebral blood flow (rcbf) spect. |
2024-06-10 |
2024-06-14 |
Not clear |
| Bang-Hoon Cho, Hyunsoo Kim, Seong-Min Choi, Soo Hyun Cho, Byeong C Ki. Differences in cognitive trajectories of dementia: Comparison Alzheimer's disease dementia and Dementia with Lewy bodies in Korean patient cohort. Dementia and geriatric cognitive disorders. 2024-06-09. PMID:38852582. |
we aimed to investigate the cognitive trajectories of alzheimer's disease dementia (add) and dementia with lewy bodies (dlb) according to the initial structural change measured by comprehensive visual rating scales (cvrs). |
2024-06-09 |
2024-06-14 |
human |
| Jianing Chi, Jiaman Hu, Ningxia Wu, Hua Cai, Cailong Lin, Yingying Lai, Jianyu Huang, Weihua Li, Peng Su, Min Li, Lin X. Causal effects for neurodegenerative diseases on the risk of myocardial infarction: a two-sample Mendelian randomization study. Aging. vol 16. 2024-06-08. PMID:38850523. |
this study aimed to investigate the potential causal associations of genetically predicted alzheimer's disease (ad), dementia with lewy bodies (dlb), parkinson's disease (pd), and multiple sclerosis (ms) with mi using two-sample mendelian randomization (tsmr). |
2024-06-08 |
2024-06-11 |
Not clear |
| Zhihui Tang, Shigeki Hirano, Yume Koizumi, Michiko Izumi, Yoshihisa Kitayama, Kosuke Yamagishi, Mitsuyoshi Tamura, Ai Ishikawa, Kouichi Kashiwado, Takashi Iimori, Hiroki Mukai, Hajime Yokota, Takuro Horikoshi, Takashi Uno, Satoshi Kuwabar. Diagnostic Sensitivity and Symptomatic Relevance of Dopamine Transporter Imaging and Myocardial Sympathetic Scintigraphy in Patients with Dementia with Lewy Bodies. Journal of Alzheimer's disease : JAD. 2024-06-07. PMID:38848178. |
dementia with lewy bodies (dlb) presents with various symptoms, posing challenges for early diagnosis challenging. |
2024-06-07 |
2024-06-10 |
Not clear |
| Hironobu Endo, Maiko Ono, Yuhei Takado, Kiwamu Matsuoka, Manami Takahashi, Kenji Tagai, Yuko Kataoka, Kosei Hirata, Keisuke Takahata, Chie Seki, Naomi Kokubo, Masayuki Fujinaga, Wakana Mori, Yuji Nagai, Koki Mimura, Katsushi Kumata, Tatsuya Kikuchi, Aki Shimozawa, Sushil K Mishra, Yoshiki Yamaguchi, Hiroshi Shimizu, Akiyoshi Kakita, Hiroyuki Takuwa, Hitoshi Shinotoh, Hitoshi Shimada, Yasuyuki Kimura, Masanori Ichise, Tetsuya Suhara, Takafumi Minamimoto, Naruhiko Sahara, Kazunori Kawamura, Ming-Rong Zhang, Masato Hasegawa, Makoto Higuch. Imaging α-synuclein pathologies in animal models and patients with Parkinson's and related diseases. Neuron. 2024-06-06. PMID:38843838. |
deposition of α-synuclein fibrils is implicated in parkinson's disease (pd) and dementia with lewy bodies (dlb), while in vivo detection of α-synuclein pathologies in these illnesses has been challenging. |
2024-06-06 |
2024-06-10 |
mouse |
| Ryota Kobayashi, Kuniyuki Iwata-Endo, Hiroshige Fujishir. Clinical presentations and diagnostic application of proposed biomarkers in psychiatric-onset prodromal dementia with Lewy bodies. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. 2024-06-05. PMID:38837629. |
research criteria for the diagnosis of prodromal dementia with lewy bodies (dlb) include three clinical subtypes: mild cognitive impairment with lewy bodies (mci-lb), delirium-onset prodromal dlb, and psychiatric-onset prodromal dlb. |
2024-06-05 |
2024-06-08 |
Not clear |
| Katharina Bolsewig, Annemartijn A J M van Unnik, Elena R Blujdea, Maria C Gonzalez, Nicholas J Ashton, Dag Aarsland, Henrik Zetterberg, Alessandro Padovani, Laura Bonanni, Brit Mollenhauer, Sebastian Schade, Rik Vandenberghe, Koen Poesen, Milica G Kramberger, Claire Paquet, Olivier Bousiges, Benjamin Cretin, Eline A J Willemse, Charlotte E Teunissen, Afina W Lemstr. Association of Plasma Amyloid, P-Tau, GFAP, and NfL With CSF, Clinical, and Cognitive Features in Patients With Dementia With Lewy Bodies. Neurology. vol 102. issue 12. 2024-06-03. PMID:38830138. |
plasma β-amyloid-1-42/1-40 (aβ42/40), phosphorylated-tau (p-tau), glial fibrillary acidic protein (gfap), and neurofilament light (nfl) have been widely examined in alzheimer disease (ad), but little is known about their reflection of copathologies, clinical importance, and predictive value in dementia with lewy bodies (dlb). |
2024-06-03 |
2024-06-06 |
Not clear |
| Melissa Scholefield, Stephanie J Church, Jingshu Xu, Stefano Patassini, Garth J S Coope. Localized Pantothenic Acid (Vitamin B5) Reductions Present Throughout the Dementia with Lewy Bodies Brain. Journal of Parkinson's disease. 2024-05-31. PMID:38820022. |
however, no studies have yet been performed to see whether such deficiencies occur across the dementia with lewy bodies (dlb) brain, or what the pattern of such dysregulation may be. |
2024-05-31 |
2024-06-02 |
Not clear |
| Rong Ye, Anna E Goodheart, Joseph J Locascio, Erin Peterec, Michael Properzi, Emma G Thibault, Erin Chuba, Keith A Johnson, Michael J Brickhouse, Alexandra Touroutoglou, John H Growdon, Bradford C Dickerson, Stephen N Gompert. Differential Vulnerability of Hippocampal Subfields to Amyloid and Tau Deposition in the Lewy Body Diseases. Neurology. vol 102. issue 12. 2024-05-30. PMID:38815233. |
alzheimer disease (ad) copathologies of β-amyloid and tau are common in the lewy body diseases (lbd), dementia with lewy bodies (dlb) and parkinson disease (pd), and target distinct hippocampal subfields compared with lewy pathology, including subiculum and ca1. |
2024-05-30 |
2024-07-16 |
Not clear |
| Vasilis-Spyridon Tseriotis, Theodoros Mavridis, Kyriaki Eleftheriadou, Georgios Konstantis, David-Dimitris Chlorogiannis, Pavlos Pavlidis, Chryssa Pourzitaki, Marianthi Arnaoutoglou, Konitsiotis Spyrido. Loss of the "swallow tail sign" on susceptibility-weighted imaging in the diagnosis of dementia with Lewy bodies: a systematic review and meta-analysis. Journal of neurology. 2024-05-27. PMID:38801432. |
dnh loss could also be of diagnostic value in dementia with lewy bodies (dlb), an a-synuclein-related pathology. |
2024-05-27 |
2024-05-31 |
Not clear |
| Vasilis-Spyridon Tseriotis, Theodoros Mavridis, Kyriaki Eleftheriadou, Georgios Konstantis, David-Dimitris Chlorogiannis, Pavlos Pavlidis, Chryssa Pourzitaki, Marianthi Arnaoutoglou, Konitsiotis Spyrido. Loss of the "swallow tail sign" on susceptibility-weighted imaging in the diagnosis of dementia with Lewy bodies: a systematic review and meta-analysis. Journal of neurology. 2024-05-27. PMID:38801432. |
we aim to quantitatively synthesize evidence, investigating the role of mri, a first-line imaging modality, in early dlb detection and differentiation from other dementias. |
2024-05-27 |
2024-05-31 |
Not clear |
| Nolwazi Z Gcwensa, Dreson L Russell, Khaliah Y Long, Charlotte F Brzozowski, Xinran Liu, Karen L Gamble, Rita M Cowell, Laura A Volpicelli-Dale. Cortico-amygdala synaptic structural abnormalities produced by templated aggregation of α-synuclein. bioRxiv : the preprint server for biology. 2024-05-27. PMID:38798467. |
parkinson's disease (pd) and dementia with lewy bodies (dlb) are characterized by neuronal α-synuclein (α-syn) inclusions termed lewy pathology, which are abundant in the amygdala. |
2024-05-27 |
2024-05-31 |
mouse |
| Eiji Matsusue, Chie Inoue, Manabu Shimoda, Tomoya Nakamura, Shota Matsumoto, Kensuke Matsumoto, Tomohiko Tanino, Kazuhiko Nakamura, Shinya Fuji. Utility of combining multiple parameters of Acta radiologica (Stockholm, Sweden : 1987). 2024-05-24. PMID:38785068. |
utility of combining multiple parameters of brain magnetic resonance imaging voxel-based morphometry (vbm) and perfusion single-photon emission computed tomography (spect) are useful for differentiating dementia with lewy bodies (dlb) from alzheimer's disease (ad). |
2024-05-24 |
2024-05-27 |
Not clear |
| Jianping Zhu, Marcus E Graziotto, Veronica Cottam, Tom Hawtrey, Liam D Adair, Benjamin G Trist, Nguyen T H Pham, Jourdin R C Rouaen, Carolyn Ohno, Marcus Heisler, Orazio Vittorio, Kay L Double, Elizabeth J Ne. Near-Infrared Ratiometric Fluorescent Probe for Detecting Endogenous Cu ACS sensors. 2024-05-24. PMID:38787339. |
for example, changes in the level and distribution of copper are reported in neuroblastoma, alzheimer's disease, and lewy body disorders, such as parkinson disease and dementia with lewy bodies (dlb). |
2024-05-24 |
2024-05-27 |
human |
| Andrew J White, Karis A Clark, Kellianne D Alexander, Nagendran Ramalingam, Tracy L Young-Pearse, Ulf Dettmer, Dennis J Selkoe, Gary P H H. A stem cell-based assay platform demonstrates alpha-synuclein dependent synaptic dysfunction in patient-derived cortical neurons. NPJ Parkinson's disease. vol 10. issue 1. 2024-05-23. PMID:38773105. |
alpha-synuclein (αs)-rich lewy bodies and neurites in the cerebral cortex correlate with the presence of dementia in parkinson disease (pd) and dementia with lewy bodies (dlb), but whether αs influences synaptic vesicle dynamics in human cortical neurons is unknown. |
2024-05-23 |
2024-05-27 |
human |
| Andrew J White, Karis A Clark, Kellianne D Alexander, Nagendran Ramalingam, Tracy L Young-Pearse, Ulf Dettmer, Dennis J Selkoe, Gary P H H. A stem cell-based assay platform demonstrates alpha-synuclein dependent synaptic dysfunction in patient-derived cortical neurons. NPJ Parkinson's disease. vol 10. issue 1. 2024-05-23. PMID:38773105. |
thus, using a robust, easily adopted assay platform, we show for the first time αs-induced synaptic dysfunction in human cortical neurons, a key cellular substrate for pd dementia and dlb. |
2024-05-23 |
2024-05-27 |
human |
| George T Kannarkat, Rebecca Zack, R Tyler Skrinak, James F Morley, Roseanne Davila-Rivera, Sanaz Arezoumandan, Katherine Dorfmann, Kelvin Luk, David A Wolk, Daniel Weintraub, Thomas F Tropea, Edward B Lee, Sharon X Xie, Ganesh Chandrasekaran, Virginia M-Y Lee, David Irwin, Rizwan S Akhtar, Alice S Chen-Plotki. α-Synuclein Conformations in Plasma Distinguish Parkinson's Disease from Dementia with Lewy Bodies. bioRxiv : the preprint server for biology. 2024-05-20. PMID:38765963. |
spread and aggregation of misfolded α-synuclein (asyn) within the brain is the pathologic hallmark of lewy body diseases (lbd), including parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2024-05-20 |
2024-05-27 |
Not clear |
| Nandkishore R Belur, Bernabe I Bustos, Steven J Lubbe, Joseph R Mazzull. Nuclear aggregates of NONO/SFPQ and A-to-I-edited RNA in Parkinson's disease and dementia with Lewy bodies. Neuron. 2024-05-18. PMID:38761794. |
parkinson's disease (pd) and dementia with lewy bodies (dlb) are classified as synucleinopathies since α-synuclein (α-syn)-containing inclusions histopathologically define these diseases. |
2024-05-18 |
2024-05-27 |
human |