| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Chen, W Yang, X Li, X Li, H Yang, Z Xu, S Y. α-Synuclein-induced internalization of NMDA receptors in hippocampal neurons is associated with reduced inward current and Ca(2+) influx upon NMDA stimulation. Neuroscience. vol 300. 2016-03-29. PMID:26003734. |
abnormal α-synuclein (α-syn) expression and aggregation have been implicated in the pathogenesis of parkinson's disease (pd), dementia with lewy bodies (dlb), and alzheimer's disease (ad). |
2016-03-29 |
2023-08-13 |
mouse |
| Jung Han Yoon, Min Kim, So Young Moon, Seok Woo Yong, Ji Man Hon. Olfactory function and neuropsychological profile to differentiate dementia with Lewy bodies from Alzheimer's disease in patients with mild cognitive impairment: A 5-year follow-up study. Journal of the neurological sciences. vol 355. issue 1-2. 2016-03-28. PMID:26076880. |
mild cognitive impairment (mci) is a well-known precursor of alzheimer's disease (ad) but often also precedes dementia with lewy bodies (dlb). |
2016-03-28 |
2023-08-13 |
Not clear |
| Eizo Iseki, Wami Marui, Namiko Nihashi, Kenji Kosak. Psychiatric symptoms typical of patients with dementia with Lewy bodies - similarity to those of levodopa-induced psychosis. Acta neuropsychiatrica. vol 14. issue 5. 2016-03-18. PMID:26984463. |
we examined psychiatric symptoms in eight cases with dementia with lewy bodies (dlb), which included visual hallucination of persons or small animals, visual illusion, metamorphosia, leibhaftige bewusstheit, personal or topographical misidentification, capgras' syndrome and reduplicative paramnesia as well as depressive state and delusion of persecution. |
2016-03-18 |
2023-08-13 |
Not clear |
| Elijah Mak, Li Su, Guy B Williams, Rosie Watson, Michael J Firbank, Andrew M Blamire, John T O'Brie. Progressive cortical thinning and subcortical atrophy in dementia with Lewy bodies and Alzheimer's disease. Neurobiology of aging. vol 36. issue 4. 2016-03-17. PMID:25649023. |
patterns of progressive cortical thinning in dementia with lewy bodies (dlb) remain poorly understood. |
2016-03-17 |
2023-08-13 |
human |
| Zuzana Nedelska, Christopher G Schwarz, Bradley F Boeve, Val J Lowe, Robert I Reid, Scott A Przybelski, Timothy G Lesnick, Jeffrey L Gunter, Matthew L Senjem, Tanis J Ferman, Glenn E Smith, Yonas E Geda, David S Knopman, Ronald C Petersen, Clifford R Jack, Kejal Kantarc. White matter integrity in dementia with Lewy bodies: a voxel-based analysis of diffusion tensor imaging. Neurobiology of aging. vol 36. issue 6. 2016-03-17. PMID:25863527. |
many patients with dementia with lewy bodies (dlb) have overlapping alzheimer's disease (ad)-related pathology, which may contribute to white matter (wm) diffusivity alterations on diffusion tensor imaging (dti). |
2016-03-17 |
2023-08-13 |
human |
| David R Howlett, David Whitfield, Mary Johnson, Johannes Attems, John T O'Brien, Dag Aarsland, Mitchell K P Lai, Jasinda H Lee, Christopher Chen, Clive Ballard, Tibor Hortobágyi, Paul T Franci. Regional Multiple Pathology Scores Are Associated with Cognitive Decline in Lewy Body Dementias. Brain pathology (Zurich, Switzerland). vol 25. issue 4. 2016-03-15. PMID:25103200. |
dementia with lewy bodies (dlb) and parkinson's disease dementia (pdd) are characterized by the presence of α-synuclein-containing lewy bodies and lewy neurites. |
2016-03-15 |
2023-08-13 |
Not clear |
| Frederic Blanc, Sean J Colloby, Nathalie Philippi, Xavier de Pétigny, Barbara Jung, Catherine Demuynck, Clélie Phillipps, Pierre Anthony, Alan Thomas, Fabrice Bing, Julien Lamy, Catherine Martin-Hunyadi, John T O'Brien, Benjamin Cretin, Ian McKeith, Jean-Paul Armspach, John-Paul Taylo. Cortical Thickness in Dementia with Lewy Bodies and Alzheimer's Disease: A Comparison of Prodromal and Dementia Stages. PloS one. vol 10. issue 6. 2016-03-15. PMID:26061655. |
to assess and compare cortical thickness (cth) of patients with prodromal dementia with lewy bodies (pro-dlb), prodromal alzheimer's disease (pro-ad), dlb dementia (dlb-d), ad dementia (ad-d) and normal ageing. |
2016-03-15 |
2023-08-13 |
Not clear |
| Rebecca Gillen, Michael J Firbank, Jim Lloyd, John T O'Brie. CT-based attenuation and scatter correction compared with uniform attenuation correction in brain perfusion SPECT imaging for dementia. Physics in medicine and biology. vol 60. issue 17. 2016-03-15. PMID:26296141. |
however, roi analysis found similar statistically significant differences between control and dementia groups and between ad and dlb groups regardless of the correction map used.we did not identify an improvement in diagnostic accuracy in images which were corrected using ct-based attenuation and scatter correction, compared with those corrected using a uniform correction map. |
2016-03-15 |
2023-08-13 |
human |
| Magda Dąbrowska, Michał Schinwelski, Emilia J Sitek, Anna Muraszko-Klaudel, Bogna Brockhuis, Zygmunt Jamrozik, Jarosław Sławe. The role of neuroimaging in the diagnosis of the atypical parkinsonian syndromes in clinical practice. Neurologia i neurochirurgia polska. vol 49. issue 6. 2016-03-07. PMID:26652877. |
atypical parkinsonian disorders (apd) are a heterogenous group of neurodegenerative diseases such as: progressive supranuclear palsy (psp), multiple system atrophy (msa), cortico-basal degeneration (cbd) and dementia with lewy bodies (dlb). |
2016-03-07 |
2023-08-13 |
Not clear |
| Nishant N Vaikath, Nour K Majbour, Katerina E Paleologou, Mustafa T Ardah, Esther van Dam, Wilma D J van de Berg, Shelley L Forrest, Laura Parkkinen, Wei-Ping Gai, Nobutaka Hattori, Masashi Takanashi, Seung-Jae Lee, David M A Mann, Yuzuru Imai, Glenda M Halliday, Jia-Yi Li, Omar M A El-Agna. Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology. Neurobiology of disease. vol 79. 2016-03-02. PMID:25937088. |
α-synuclein (α-syn), a small protein that has the intrinsic propensity to aggregate, is implicated in several neurodegenerative diseases including parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa), which are collectively known as synucleinopathies. |
2016-03-02 |
2023-08-13 |
Not clear |
| M L Fantini, L Ferini-Stramb. Idiopathic rapid eye movement sleep behaviour disorder. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 28 Suppl 1. 2016-02-23. PMID:17235428. |
the latter may be isolated (idiopathic rbd), or associated with other neurological diseases (symptomatic rbd), especially with a group of neurodegenerative disease called alpha-synucleinopathies, which includes parkinson's disease, dementia with lewy bodies (dlb) and multiple system atrophy. |
2016-02-23 |
2023-08-12 |
Not clear |
| Luis R Peraza, Marcus Kaiser, Michael Firbank, Sara Graziadio, Laura Bonanni, Marco Onofrj, Sean J Colloby, Andrew Blamire, John O'Brien, John-Paul Taylo. fMRI resting state networks and their association with cognitive fluctuations in dementia with Lewy bodies. NeuroImage. Clinical. vol 4. 2016-02-22. PMID:24818081. |
cognitive fluctuations are a core symptom in dementia with lewy bodies (dlb) and may relate to pathological alterations in distributed brain networks. |
2016-02-22 |
2023-08-13 |
Not clear |
| Kenji Kosaka, Yuta Manab. The first autopsied case of diffuse Lewy body disease (DLBD): re-examination by recent immunostaining methods: The 50th Anniversary of Japanese Society of Neuropathology. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 30. issue 5. 2016-02-17. PMID:20500449. |
based on these studies the term "dementia with lewy bodies (dlb)" was proposed in 1996. |
2016-02-17 |
2023-08-12 |
Not clear |
| Kenji Kosaka, Yuta Manab. The first autopsied case of diffuse Lewy body disease (DLBD): re-examination by recent immunostaining methods: The 50th Anniversary of Japanese Society of Neuropathology. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 30. issue 5. 2016-02-17. PMID:20500449. |
since 1980, we have insisted that dlb, parkinson disease (pd), and pd with dementia (pdd) should be understood within the spectrum of lewy body disease. |
2016-02-17 |
2023-08-12 |
Not clear |
| Mitsuhiro Yoshita, Heii Arai, Hiroyuki Arai, Tetsuaki Arai, Takashi Asada, Hiroshige Fujishiro, Haruo Hanyu, Osamu Iizuka, Eizo Iseki, Kenichi Kashihara, Kenji Kosaka, Hirotaka Maruno, Katsuyoshi Mizukami, Yoshikuni Mizuno, Etsuro Mori, Kenichi Nakajima, Hiroyuki Nakamura, Seigo Nakano, Kenji Nakashima, Yoshiyuki Nishio, Satoshi Orimo, Miharu Samuraki, Akira Takahashi, Junichi Taki, Takahiko Tokuda, Katsuya Urakami, Kumiko Utsumi, Kenji Wada, Yukihiko Washimi, Junichi Yamasaki, Shouhei Yamashina, Masahito Yamad. Diagnostic accuracy of 123I-meta-iodobenzylguanidine myocardial scintigraphy in dementia with Lewy bodies: a multicenter study. PloS one. vol 10. issue 3. 2016-02-16. PMID:25793585. |
dementia with lewy bodies (dlb) needs to be distinguished from alzheimer's disease (ad) because of important differences in patient management and outcome. |
2016-02-16 |
2023-08-13 |
Not clear |
| Monica Federoff, Lucia V Schottlaender, Henry Houlden, Andrew Singleto. Multiple system atrophy: the application of genetics in understanding etiology. Clinical autonomic research : official journal of the Clinical Autonomic Research Society. vol 25. issue 1. 2016-02-11. PMID:25687905. |
as a member of the alpha-synucleinopathy family, which is defined by its well-demarcated alpha-synuclein-immunoreactive inclusions and aggregation, msa's clinical presentation exhibits several overlapping features with other members including parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2016-02-11 |
2023-08-13 |
Not clear |
| Kelly M Landy, David P Salmon, Douglas Galasko, J Vincent Filoteo, Elena K Festa, William C Heindel, Lawrence A Hansen, Joanne M Hamilto. Motion discrimination in dementia with Lewy bodies and Alzheimer disease. Neurology. vol 85. issue 16. 2016-02-11. PMID:26400581. |
visual processing abilities of patients with dementia with lewy bodies (dlb) or alzheimer disease (ad) dementia were assessed psychophysically using a simple horizontal motion discrimination task that engages the dorsal visual processing stream. |
2016-02-11 |
2023-08-13 |
Not clear |
| Katsuji Kobayashi, Hiroyuki Nakano, Noriko Akiyama, Takashi Maeda, Sanae Yamamor. Pure psychiatric presentation of the Lewy body disease is depression--an analysis of 60 cases verified with myocardial meta-iodobenzylguanidine study. International journal of geriatric psychiatry. vol 30. issue 6. 2016-02-09. PMID:25335897. |
parkinson's disease (pd), parkinson's disease with dementia (pdd) and dementia with lewy bodies (dlb) were collectively termed lewy body disease (lbd). |
2016-02-09 |
2023-08-13 |
human |
| Kazumi Ota, Norio Murayama, Koji Kasanuki, Daizo Kondo, Hiroshige Fujishiro, Heii Arai, Kiyoshi Sato, Eizo Isek. Visuoperceptual assessments for differentiating dementia with Lewy bodies and Alzheimer's disease: illusory contours and other neuropsychological examinations. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists. vol 30. issue 3. 2016-02-02. PMID:25908613. |
we examined the utility of illusory contours (ics) for the differentiation of dementia with lewy bodies (dlb) from alzheimer's disease (ad). |
2016-02-02 |
2023-08-13 |
human |
| Tatsuru Kitamura, Shinnichi Tochimoto, Maki Kitamura, Shuhei Madachi, Shoryoku Hin. Outcomes of Inpatient Treatment for Behavioral and Psychological Symptoms of Dementia in Alzheimer's Disease Versus Dementia With Lewy Bodies. The primary care companion for CNS disorders. vol 17. issue 5. 2016-02-02. PMID:26835172. |
most community-based studies have shown a more malignant clinical course for patients with dementia with lewy bodies (dlb) than alzheimer's disease (ad). |
2016-02-02 |
2023-08-13 |
Not clear |