| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Annachiara Cagnin, Cinzia Bussè, Nela Jelcic, Francesca Gnoato, Micaela Mitolo, Paolo Caffarr. High specificity of MMSE pentagon scoring for diagnosis of prodromal dementia with Lewy bodies. Parkinsonism & related disorders. vol 21. issue 3. 2015-11-17. PMID:25547859. |
patients with dementia with lewy bodies (dlb) may display a different cognitive pattern from alzheimer's disease (ad) with more severe impairment performing visuospatial/visuoconstructive tasks. |
2015-11-17 |
2023-08-13 |
Not clear |
| Yixuan Wang, Zheming Yu, Huimin Ren, Jian Wang, Jianjun Wu, Yan Chen, Zhengtong Din. The synergistic effect between β-amyloid(1-42) and α-synuclein on the synapses dysfunction in hippocampal neurons. Journal of chemical neuroanatomy. vol 63. 2015-11-12. PMID:25445382. |
this study was to explore the molecular mechanisms underpinning the synergetic effect between β-amyloid (aβ) and α-synuclein (α-syn) on synapses dysfunction during the development of neurodegenerative disorders including parkinson's disease (pd), dementia with lewy bodies (dlb) and alzheimer disease (ad). |
2015-11-12 |
2023-08-13 |
Not clear |
| Kunikazu Tanji, Saori Odagiri, Atsushi Maruyama, Fumiaki Mori, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayash. Alteration of autophagosomal proteins in the brain of multiple system atrophy. Neurobiology of disease. vol 49. 2015-11-10. PMID:22959883. |
recent studies have shown that impairment of the autophagy-lysosome system is associated with formation of cytoplasmic inclusions observed in various neurodegenerative disorders including parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2015-11-10 |
2023-08-12 |
Not clear |
| David R Whitfield, Julie Vallortigara, Amani Alghamdi, David Howlett, Tibor Hortobágyi, Mary Johnson, Johannes Attems, Stephen Newhouse, Clive Ballard, Alan J Thomas, John T O'Brien, Dag Aarsland, Paul T Franci. Assessment of ZnT3 and PSD95 protein levels in Lewy body dementias and Alzheimer's disease: association with cognitive impairment. Neurobiology of aging. vol 35. issue 12. 2015-11-09. PMID:25104558. |
we investigated the levels of znt3 and postsynaptic density protein 95 (psd95), a marker of the postsynaptic terminal, in people with parkinson's disease dementia (pdd, n = 31), dementia with lewy bodies (dlb, n = 44), alzheimer's disease (ad, n = 16), and controls (n = 24), using semiquantitative western blotting and immunohistochemistry in 3 cortical regions. |
2015-11-09 |
2023-08-13 |
mouse |
| Yoshinari Kawai, Rina Miura, Masashi Tsujimoto, Takashi Sakurai, Akiko Yamaoka, Akinori Takeda, Yutaka Arahata, Yukihiko Washimi, Teruhiko Kachi, Kenji Tob. Neuropsychological differentiation between Alzheimer's disease and dementia with Lewy bodies in a memory clinic. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. vol 13. issue 3. 2015-11-09. PMID:25913764. |
the aim of this study was to identify a useful neuropsychological instrument for making a differential clinical diagnosis between alzheimer's disease (ad) and dementia with lewy bodies (dlb). |
2015-11-09 |
2023-08-13 |
Not clear |
| Hiromichi Tsukada, Hiroshi Fujii, Kazuyuki Aihara, Ichiro Tsud. Computational model of visual hallucination in dementia with Lewy bodies. Neural networks : the official journal of the International Neural Network Society. vol 62. 2015-11-02. PMID:25282547. |
patients with dementia with lewy bodies (dlb) frequently experience visual hallucination (vh), which has been aptly described as people seeing things that are not there. |
2015-11-02 |
2023-08-13 |
Not clear |
| Hennie Lee, Geert J F Brekelmans, Gerwin Rok. The EEG as a diagnostic tool in distinguishing between dementia with Lewy bodies and Alzheimer's disease. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 126. issue 9. 2015-10-30. PMID:25534493. |
current diagnostic criteria for dementia with lewy bodies (dlb) regard electroencephalogram (eeg) abnormalities as a supportive feature. |
2015-10-30 |
2023-08-13 |
Not clear |
| Jose Bras, Rita Guerreiro, Lee Darwent, Laura Parkkinen, Olaf Ansorge, Valentina Escott-Price, Dena G Hernandez, Michael A Nalls, Lorraine N Clark, Lawrence S Honig, Karen Marder, Wiesje M Van Der Flier, Afina Lemstra, Philip Scheltens, Ekaterina Rogaeva, Peter St George-Hyslop, Elisabet Londos, Henrik Zetterberg, Sara Ortega-Cubero, Pau Pastor, Tanis J Ferman, Neill R Graff-Radford, Owen A Ross, Imelda Barber, Anne Braae, Kristelle Brown, Kevin Morgan, Walter Maetzler, Daniela Berg, Claire Troakes, Safa Al-Sarraj, Tammaryn Lashley, Yaroslau Compta, Tamas Revesz, Andrew Lees, Nigel Cairns, Glenda M Halliday, David Mann, Stuart Pickering-Brown, Dennis W Dickson, Andrew Singleton, John Hard. Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies. Human molecular genetics. vol 23. issue 23. 2015-10-29. PMID:24973356. |
clinical and neuropathological similarities between dementia with lewy bodies (dlb), parkinson's and alzheimer's diseases (pd and ad, respectively) suggest that these disorders may share etiology. |
2015-10-29 |
2023-08-13 |
Not clear |
| Stewart F Graham, Muhammad Bin Nasarauddin, Manus Carey, Bernadette McGuinness, Christian Holscher, Patrick G Kehoe, Seth Love, Anthony P Passmore, Christopher T Elliott, Andrew Meharg, Brian D Gree. Quantitative measurement of [Na+] and [K+] in postmortem human brain tissue indicates disturbances in subjects with Alzheimer's disease and dementia with Lewy bodies. Journal of Alzheimer's disease : JAD. vol 44. issue 3. 2015-10-26. PMID:25362038. |
we analyzed parietal cortex (brodmann area 7) from 28 cognitively normal age-matched controls, 15 cases of moderate ad, 30 severe ad, and 15 dementia with lewy bodies (dlb). |
2015-10-26 |
2023-08-13 |
human |
| S Pablo Sardi, Seng H Cheng, Lamya S Shihabuddi. Gaucher-related synucleinopathies: the examination of sporadic neurodegeneration from a rare (disease) angle. Progress in neurobiology. vol 125. 2015-10-26. PMID:25573151. |
heterozygous mutations in the lysosomal glucocerebrosidase gene (gba1) have recently been recognized as the highest genetic risk factor for the development of α-synuclein aggregation disorders ("synucleinopathies"), including parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2015-10-26 |
2023-08-13 |
Not clear |
| Pasquale Anthony Della Rosa, Chiara Cerami, Francesca Gallivanone, Annapaola Prestia, Anna Caroli, Isabella Castiglioni, Maria Carla Gilardi, Giovanni Frisoni, Karl Friston, John Ashburner, Daniela Peran. A standardized [18F]-FDG-PET template for spatial normalization in statistical parametric mapping of dementia. Neuroinformatics. vol 12. issue 4. 2015-10-22. PMID:24952892. |
we investigated the statistical sensitivity and registration accuracy of normalization procedures based on the standard and new template-at the single-subject and group level-independently for subjects with mild cognitive impairment (mci), probable alzheimer's disease (ad), frontotemporal lobar degeneration (ftld) and dementia with lewy bodies (dlb). |
2015-10-22 |
2023-08-13 |
human |
| Kay Seidel, Josefine Mahlke, Sonny Siswanto, Reijko Krüger, Helmut Heinsen, Georg Auburger, Mohamed Bouzrou, Lea T Grinberg, Helmut Wicht, Horst-Werner Korf, Wilfred den Dunnen, Udo Rü. The brainstem pathologies of Parkinson's disease and dementia with Lewy bodies. Brain pathology (Zurich, Switzerland). vol 25. issue 2. 2015-10-22. PMID:24995389. |
parkinson's disease (pd) and dementia with lewy bodies (dlb) are among the human synucleinopathies, which show alpha-synuclein immunoreactive neuronal and/or glial aggregations and progressive neuronal loss in selected brain regions (eg, substantia nigra, ventral tegmental area, pedunculopontine nucleus). |
2015-10-22 |
2023-08-13 |
human |
| J Sun, N J Cairns, J S Perlmutter, R H Mach, J X. Regulation of dopamine D₃ receptor in the striatal regions and substantia nigra in diffuse Lewy body disease. Neuroscience. vol 248. 2015-10-20. PMID:23732230. |
in this study, a novel d₃-preferring radioligand [(3)h]wc-10 and a d₂-preferring radioligand [(3)h]raclopride were used and the absolute densities of the dopamine d₃ and d₂ receptors were determined in the striatal regions and substantia nigra (sn) from postmortem brains from five cases of dlbd, which included dementia with lewy bodies (dlb, n=4) and parkinson disease dementia (pdd, n=1). |
2015-10-20 |
2023-08-12 |
Not clear |
| Nayuta Namioka, Haruo Hanyu, Hirokuni Hatanaka, Raita Fukasawa, Hirofumi Sakurai, Toshihiko Iwamot. Comprehensive geriatric assessment in elderly patients with dementia. Geriatrics & gerontology international. vol 15. issue 1. 2015-10-15. PMID:25164434. |
we compared the results obtained by the cga of patients with alzheimer's disease (ad), vascular dementia (vad) and dementia with lewy bodies (dlb), and determined the relationship between functional deficits and clinical characteristics in each type of dementia. |
2015-10-15 |
2023-08-13 |
Not clear |
| Takahiro Ikura, Hiroshige Fujishiro, Yukitoshi Takahashi, Makoto Yoneda, Tomoyuki Saito, Yuhei Chiba, Ayuko Kamada, Omi Katsuse, Yoshio Hirayas. [A Patient with Probable Dementia with Lewy Bodies and Positive Autoantibodies against the Anti-NH2-terminal of α-Enolase]. Brain and nerve = Shinkei kenkyu no shinpo. vol 67. issue 7. 2015-10-09. PMID:26160824. |
dementia with lewy bodies (dlb) is clinically characterized by progressive dementia that is frequently accompanied by neurological and psychiatric manifestations. |
2015-10-09 |
2023-08-13 |
Not clear |
| Raffaele Manni, Michele Terzagh. Sleep-disordered breathing in dementia with Lewy bodies. Current neurology and neuroscience reports. vol 15. issue 3. 2015-09-29. PMID:25663033. |
dementia with lewy bodies (dlb) is the second most common form of dementia, and it is very frequently associated with changes in sleep patterns. |
2015-09-29 |
2023-08-13 |
Not clear |
| Teresa Bachhuber, Natalie Katzmarski, Joanna F McCarter, Desiree Loreth, Sabina Tahirovic, Frits Kamp, Claudia Abou-Ajram, Brigitte Nuscher, Alberto Serrano-Pozo, Alexandra Müller, Marco Prinz, Harald Steiner, Bradley T Hyman, Christian Haass, Melanie Meyer-Luehman. Inhibition of amyloid-β plaque formation by α-synuclein. Nature medicine. vol 21. issue 7. 2015-09-28. PMID:26099047. |
an overlap of pathologies is found in most individuals with dementia with lewy bodies (dlb) and in more than 50% of ad cases. |
2015-09-28 |
2023-08-13 |
mouse |
| Zuzana Walker, Emilio Moreno, Alan Thomas, Fraser Inglis, Naji Tabet, Michael Rainer, Gilberto Pizzolato, Alessandro Padovan. Clinical usefulness of dopamine transporter SPECT imaging with 123I-FP-CIT in patients with possible dementia with Lewy bodies: randomised study. The British journal of psychiatry : the journal of mental science. vol 206. issue 2. 2015-09-25. PMID:25431431. |
dementia with lewy bodies (dlb) is underrecognised in clinical settings. |
2015-09-25 |
2023-08-13 |
Not clear |
| Davide Chiasserini, Silvia Paciotti, Paolo Eusebi, Emanuele Persichetti, Anna Tasegian, Marzena Kurzawa-Akanbi, Patrick F Chinnery, Christopher M Morris, Paolo Calabresi, Lucilla Parnetti, Tommaso Beccar. Selective loss of glucocerebrosidase activity in sporadic Parkinson's disease and dementia with Lewy bodies. Molecular neurodegeneration. vol 10. 2015-09-25. PMID:25881142. |
recently, gcase activity has been shown to be decreased in substantia nigra and in cerebrospinal fluid of patients diagnosed with pd or dementia with lewy bodies (dlb). |
2015-09-25 |
2023-08-13 |
human |
| Yuhei Chiba, Hiroshige Fujishiro, Kazumi Ota, Koji Kasanuki, Heii Arai, Yoshio Hirayasu, Kiyoshi Sato, Eizo Isek. Clinical profiles of dementia with Lewy bodies with and without Alzheimer's disease-like hypometabolism. International journal of geriatric psychiatry. vol 30. issue 3. 2015-09-24. PMID:24839913. |
it is well known that alzheimer's disease (ad)-type pathology is commonly present in dementia with lewy bodies (dlb) brains and that the degree of ad-type pathology has an influence on the clinical characteristics of dlb. |
2015-09-24 |
2023-08-13 |
Not clear |