Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Marleen van de Beek, Inger van Steenoven, Inez H G B Ramakers, Pauline Aalten, Huiberdina L Koek, Marcel G M Olde Rikkert, Judith Manniën, Janne M Papma, Frank Jan de Jong, Afina W Lemstra, Wiesje M van der Flie. Trajectories and Determinants of Quality of Life in Dementia with Lewy Bodies and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 70. issue 2. 2020-10-01. PMID:31177218. |
research investigating longitudinal qol in dementia with lewy bodies (dlb) is currently lacking. |
2020-10-01 |
2023-08-13 |
Not clear |
Ying-Jui Ho, Mei-Shiuan Shen, Chun-Hwei Tai, Hsin-Hua Li, Jian-Horng Chen, Wen-Chieh Liao, Pai-Yi Chiu, I-Yen Lee, Chih-Li Lin, Ching-Sui Hun. Use of Ceftriaxone in Treating Cognitive and Neuronal Deficits Associated With Dementia With Lewy Bodies. Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31178684. |
dementia with lewy bodies (dlb) is caused by accumulation of lewy bodies, destruction of mitochondria, and excess of glutamate in synapses, which eventually leads to excitotoxicity, neurodegeneration, and cognitive impairments. |
2020-10-01 |
2023-08-13 |
human |
Iracema Leroi, Sabina Vatter, Lesley-Anne Carter, Sarah J Smith, Vasiliki Orgeta, Ellen Poliakoff, Monty A Silverdale, Jason Raw, David J Ahearn, Christine Taylor, Joanne Rodda, Tarek Abdel-Ghany, Sheree A McCormic. Parkinson's-adapted cognitive stimulation therapy: a pilot randomized controlled clinical trial. Therapeutic advances in neurological disorders. vol 12. 2020-10-01. PMID:31320931. |
cognitive stimulation therapy (cst) is widely used with people with dementia, but there is no evidence of its efficacy in mild cognitive impairment or dementia in parkinson's disease (pd-mci; pdd) or dementia with lewy bodies (dlb). |
2020-10-01 |
2023-08-13 |
Not clear |
Kensuke Ikenaka, Mari Suzuki, Hideki Mochizuki, Yoshitaka Naga. Lipids as Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31333408. |
lipids as aggregation of α-synuclein (αsyn) plays a central role in the pathogenesis of parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2020-10-01 |
2023-08-13 |
Not clear |
Hiroshi Matsuda, Kota Yokoyama, Noriko Sato, Kengo Ito, Kiyotaka Nemoto, Hiroshi Oba, Haruo Hanyu, Hidekazu Kanetaka, Sunao Mizumura, Shin Kitamura, Hitoshi Shinotoh, Hitoshi Shimada, Tetsuya Suhara, Hitoshi Terada, Tomoya Nakatsuka, Shinobu Kawakatsu, Hiroshi Hayashi, Takashi Asada, Tetsutaro Ono, Tomoaki Goto, Keiko Shigemor. Differentiation Between Dementia With Lewy Bodies And Alzheimer's Disease Using Voxel-Based Morphometry Of Structural MRI: A Multicenter Study. Neuropsychiatric disease and treatment. vol 15. 2020-10-01. PMID:31571887. |
the differential diagnosis of dementia with lewy bodies (dlb) and alzheimer's disease (ad) is particularly important because dlb patients respond better to cholinesterase inhibitors but sometimes exhibit sensitivity to neuroleptics, which may cause worsening of clinical status. |
2020-10-01 |
2023-08-13 |
Not clear |
Kurt Segers, Florence Benoit, Jean-Marie Meyts, Murielle Surqui. Anxiety symptoms are quantitatively and qualitatively different in dementia with Lewy bodies than in Alzheimer's disease in the years preceding clinical diagnosis. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. vol 20. issue 3. 2020-10-01. PMID:31782249. |
dementia with lewy bodies (dlb) is a common but underdiagnosed type of cognitive impairment and dementia. |
2020-10-01 |
2023-08-13 |
Not clear |
Maja Trošt, Matej Perovnik, Zvezdan Pirtoše. Correlations of Neuropsychological and Metabolic Brain Changes in Parkinson's Disease and Other α-Synucleinopathies. Frontiers in neurology. vol 10. 2020-10-01. PMID:31798525. |
in dementia with lewy bodies (dlb) the cognitive impairment develops early or even precedes parkinsonism and it is more pronounced in visuospatial skills and memory. |
2020-10-01 |
2023-08-13 |
Not clear |
Wen-Ying Ma, Qun Yao, Guan-Jie Hu, Chao-Yong Xiao, Jing-Ping Shi, Jiu Che. Dysfunctional Dynamics of Intra- and Inter-network Connectivity in Dementia With Lewy Bodies. Frontiers in neurology. vol 10. 2020-10-01. PMID:31849824. |
dementia with lewy bodies (dlb) is characterized by the transient fluctuating cognition and recurrent visual hallucinations, which may be caused by disorders of the intrinsic brain network dynamics. |
2020-10-01 |
2023-08-13 |
Not clear |
Sho Ochiai, Hiroko Sugawara, Yusuke Kajio, Hibiki Tanaka, Tomohisa Ishikawa, Ryuji Fukuhara, Tadashi Jono, Mamoru Hashimot. Delusional parasitosis in dementia with Lewy bodies: a case report. Annals of general psychiatry. vol 18. 2020-10-01. PMID:31892935. |
dementia with lewy bodies (dlb) is characterized by fluctuating cognitive impairments, recurrent visual hallucinations, the motor symptoms of parkinsonism and rem sleep behavior disorder. |
2020-10-01 |
2023-08-13 |
Not clear |
R A. Armstrong, P L. Lantos, N J. Cairn. The spatial patterns of pathological brain lesions in 12 patients with corticobasal degeneration. Pathophysiology : the official journal of the International Society for Pathophysiology. vol 8. issue 1. 2020-09-30. PMID:11476973. |
hence, bn and tau+ lesions in cbd exhibit similar spatial patterns as lesions in alzheimer's disease (ad), dementia with lewy bodies (dlb) and pick's disease (pd). |
2020-09-30 |
2023-08-12 |
Not clear |
Siroos Mirzaei, Peter Knoll, Horst Koehn, Thomas Brueck. Assessment of diffuse Lewy body disease by 2-[18F]fluoro-2-deoxy-D-glucose positron emission tomography (FDG PET). BMC nuclear medicine. vol 3. issue 1. 2020-09-30. PMID:12625839. |
conclusion: the pattern of diffuse glucose hypometabolism in the entire cortex including the occipital region seems to be a typical feature of dlb that is distinctive from dementia of alzheimer's disease. |
2020-09-30 |
2023-08-12 |
human |
James E Galvi. IMPROVING THE CLINICAL DETECTION OF LEWY BODY DEMENTIA WITH THE LEWY BODY COMPOSITE RISK SCORE. Alzheimer's & dementia (Amsterdam, Netherlands). vol 1. issue 3. 2020-09-30. PMID:26405688. |
dementia with lewy bodies (dlb) is a challenge to diagnose, particularly outside of expert centers with long delays in diagnosis leading to significant burden to patients and caregivers. |
2020-09-30 |
2023-08-13 |
Not clear |
Yasuhiro Nagahama, Tomoko Okina, Norio Suzuk. Neuropsychological Differences Related to Age in Dementia with Lewy Bodies. Dementia and geriatric cognitive disorders extra. vol 7. issue 2. 2020-09-30. PMID:28690632. |
to examine the influence of age on neuropsychological performances in dementia with lewy bodies (dlb) and alzheimer disease (ad) patients. |
2020-09-30 |
2023-08-13 |
Not clear |
Chris Smart, Hamish McAllister-Williams, David Andrew Cousin. Acetylcholinesterase inhibitors in treatment-resistant psychotic depression. Therapeutic advances in psychopharmacology. vol 8. issue 1. 2020-09-30. PMID:29344344. |
visual hallucinations may arise from a dysregulation of brain cholinergic systems and acetylcholinesterase inhibitors (acheis) can treat such hallucinations in dementia with lewy bodies (dlb). |
2020-09-30 |
2023-08-13 |
Not clear |
Georgina M Aldridge, Allison Birnschein, Natalie L Denburg, Nandakumar S Narayana. Parkinson's Disease Dementia and Dementia with Lewy Bodies Have Similar Neuropsychological Profiles. Frontiers in neurology. vol 9. 2020-09-30. PMID:29593630. |
parkinson's disease dementia (pdd) and dementia with lewy bodies (dlb) are common causes of dementia worldwide. |
2020-09-30 |
2023-08-13 |
Not clear |
Laia Perez-Roca, Cristina Adame-Castillo, Jaume Campdelacreu, Lourdes Ispierto, Dolores Vilas, Ramon Rene, Ramiro Alvarez, Jordi Gascon-Bayarri, Maria A Serrano-Munoz, Aurelio Ariza, Katrin Beye. Glucocerebrosidase mRNA is Diminished in Brain of Lewy Body Diseases and Changes with Disease Progression in Blood. Aging and disease. vol 9. issue 2. 2020-09-30. PMID:29896411. |
parkinson disease (pd) and dementia with lewy bodies (dlb) are lewy body diseases characterized by abnormal alpha-synuclein deposits and overlapping pathological features in the brain. |
2020-09-30 |
2023-08-13 |
Not clear |
Manish Verma, Zachary Wills, Charleen T Ch. Excitatory Dendritic Mitochondrial Calcium Toxicity: Implications for Parkinson's and Other Neurodegenerative Diseases. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:30116173. |
while this response may augment mitochondrial respiration, limiting classic excitotoxic injury in the short term, recent studies employing live calcium imaging and molecular manipulation of calcium transporter activities suggest that mitochondrial calcium overload plays a key role in parkinson's disease (pd), alzheimer's disease (ad), amyotrophic lateral sclerosis (als), and related dementias [pd with dementia (pdd), dementia with lewy bodies (dlb), and frontotemporal dementia (ftd)]. |
2020-09-30 |
2023-08-13 |
Not clear |
Ulf Dettme. Rationally Designed Variants of α-Synuclein Illuminate Its Frontiers in neuroscience. vol 12. 2020-09-30. PMID:30319334. |
yet to interfere with disease pathogenesis, we must dissect how small changes in αs homeostasis may give rise to parkinson's disease (pd), dementia with lewy bodies (dlb) and other human synucleinopathies. |
2020-09-30 |
2023-08-13 |
human |
Paula Harman, Christine Law, Shahina Pardhan, ZhiHao Henry Lin, Mark Johnson, Silke Walter, Klaus Fassbender, Richard Aspinall, Iris Q Grunwal. Technical note: can resting state functional MRI assist in routine clinical diagnosis? BJR case reports. vol 4. issue 4. 2020-09-30. PMID:30931142. |
despite some differences in clinical presentation, it is often difficult to differentiate between dementia with lewy bodies (dlb), clinical alzheimer's dementia (ad) and parkinson's disease dementia. |
2020-09-30 |
2023-08-13 |
human |
Malakooti N, Fowler C, Volitakis I, McLean Ca, Kim Rc, Bush Ai, Rembach A, Pritchard Ma, Finkelstein DI, Adlard P. The Down Syndrome-Associated Protein, Regulator of Calcineurin-1, is Altered in Alzheimer's Disease and Dementia with Lewy Bodies. Journal of Alzheimer's disease & Parkinsonism. vol 9. issue 2. 2020-09-30. PMID:31263630. |
we also examined rcan1 and itsn1-s and -l in post-mortem brain tissue in a separate cohort of patients with ad or other types of dementia including dementia with lewy bodies (dlb) and non-alzheimer's disease dementia. |
2020-09-30 |
2023-08-13 |
Not clear |