Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Inês Caldeira Brás, Antonio Dominguez-Meijide, Ellen Gerhardt, David Koss, Diana F Lázaro, Patrícia I Santos, Eftychia Vasili, Mary Xylaki, Tiago Fleming Outeir. Synucleinopathies: Where we are and where we need to go. Journal of neurochemistry. vol 153. issue 4. 2020-10-28. PMID:31957016. |
this group of disorders includes parkinson's disease, dementia with lewy bodies (dlb), multiple systems atrophy, and pure autonomic failure (paf). |
2020-10-28 |
2023-08-13 |
human |
Tomomichi Iizuka, Makoto Fukasawa, Masashi Kameyam. Deep-learning-based imaging-classification identified cingulate island sign in dementia with Lewy bodies. Scientific reports. vol 9. issue 1. 2020-10-27. PMID:31222138. |
the differentiation of dementia with lewy bodies (dlb) from alzheimer's disease (ad) using brain perfusion single photon emission tomography is important but is challenging because these conditions exhibit typical features. |
2020-10-27 |
2023-08-13 |
Not clear |
Antonio Heras-Garvin, Nadia Stefanov. From Synaptic Protein to Prion: The Long and Controversial Journey of α-Synuclein. Frontiers in synaptic neuroscience. vol 12. 2020-10-22. PMID:33071772. |
moreover, α-syn became a protein of interest for neurologists and neuroscientists when mutations in its gene were found associated with parkinson's disease (pd) and even more when α-syn protein deposits were observed in the brain of pd, dementia with lewy bodies (dlb), and multiple system atrophy (msa) patients. |
2020-10-22 |
2023-08-13 |
Not clear |
Yuka Oishi, Toru Imamura, Tatsuo Shimomura, Kyoko Suzuk. Vegetable Freshness Perception in Dementia with Lewy Bodies and Alzheimer's Disease. Dementia and geriatric cognitive disorders extra. vol 10. issue 2. 2020-10-22. PMID:33082771. |
although various visual function deficits have been reported in patients with alzheimer's disease (ad) and dementia with lewy bodies (dlb), vegetable freshness perception has not been thoroughly examined. |
2020-10-22 |
2023-08-13 |
Not clear |
Manuel Schweighauser, Yang Shi, Airi Tarutani, Fuyuki Kametani, Alexey G Murzin, Bernardino Ghetti, Tomoyasu Matsubara, Taisuke Tomita, Takashi Ando, Kazuko Hasegawa, Shigeo Murayama, Mari Yoshida, Masato Hasegawa, Sjors H W Scheres, Michel Goeder. Structures of α-synuclein filaments from multiple system atrophy. Nature. vol 585. issue 7825. 2020-10-21. PMID:32461689. |
synucleinopathies, which include multiple system atrophy (msa), parkinson's disease, parkinson's disease with dementia and dementia with lewy bodies (dlb), are human neurodegenerative diseases |
2020-10-21 |
2023-08-13 |
human |
Zhe Kang Law, Carein Todd, Ramtin Mehraram, Julia Schumacher, Mark R Baker, Fiona E N LeBeau, Alison Yarnall, Marco Onofrj, Laura Bonanni, Alan Thomas, John-Paul Taylo. The Role of EEG in the Diagnosis, Prognosis and Clinical Correlations of Dementia with Lewy Bodies-A Systematic Review. Diagnostics (Basel, Switzerland). vol 10. issue 9. 2020-10-20. PMID:32825520. |
despite improvements in diagnostic criteria for dementia with lewy bodies (dlb), the ability to discriminate dlb from alzheimer's disease (ad) and other dementias remains suboptimal. |
2020-10-20 |
2023-08-13 |
Not clear |
Zhe Kang Law, Carein Todd, Ramtin Mehraram, Julia Schumacher, Mark R Baker, Fiona E N LeBeau, Alison Yarnall, Marco Onofrj, Laura Bonanni, Alan Thomas, John-Paul Taylo. The Role of EEG in the Diagnosis, Prognosis and Clinical Correlations of Dementia with Lewy Bodies-A Systematic Review. Diagnostics (Basel, Switzerland). vol 10. issue 9. 2020-10-20. PMID:32825520. |
we included 43 studies comparing eeg in dlb with other diagnoses, 42 of them included a comparison of dlb with ad, 10 studies compared dlb with parkinson's disease dementia, and 6 studies compared dlb with other dementias. |
2020-10-20 |
2023-08-13 |
Not clear |
Bruno Di Marco Vieira, Rowan A W Radford, Junna Hayashi, Emma D Eaton, Ben Greenaway, Mark Jambas, Eugen B Petcu, Roger S Chung, Dean L Pountne. Extracellular Alpha-Synuclein Promotes a Neuroinhibitory Secretory Phenotype in Astrocytes. Life (Basel, Switzerland). vol 10. issue 9. 2020-10-20. PMID:32911644. |
multiple system atrophy (msa) and dementia with lewy bodies (dlb) are α-synucleinopathies that exhibit widespread astrogliosis as a component of the neuroinflammatory response. |
2020-10-20 |
2023-08-13 |
human |
Elizabeth A Coon, Jay N Mandrekar, Sarah E Berini, Eduardo E Benarroch, Paola Sandroni, Phillip A Low, Wolfgang Singe. Predicting phenoconversion in pure autonomic failure. Neurology. vol 95. issue 7. 2020-10-16. PMID:32546656. |
to determine predicting factors and frequency of phenoconversion from pure autonomic failure (paf) into a synucleinopathy with motor or cognitive involvement of multiple system atrophy (msa), parkinson disease (pd), or dementia with lewy bodies (dlb). |
2020-10-16 |
2023-08-13 |
Not clear |
b' Estrella Morenas-Rodr\\xc3\\xadguez, Daniel Alcolea, Marc Su\\xc3\\xa1rez-Calvet, Laia Mu\\xc3\\xb1oz-Llahuna, Eduard Vilaplana, Isabel Sala, Andrea Subirana, Marta Querol-Vilaseca, Mar\\xc3\\xada Carmona-Iragui, Ignacio Ill\\xc3\\xa1n-Gala, Roser Ribosa-Nogu\\xc3\\xa9, Rafael Blesa, Christian Haass, Juan Fortea, Alberto Lle\\xc3\\xb. Different pattern of CSF glial markers between dementia with Lewy bodies and Alzheimer\'s disease. Scientific reports. vol 9. issue 1. 2020-10-15. PMID:31127154.' |
the role of innate immunity in dementia with lewy bodies (dlb) has been little studied. |
2020-10-15 |
2023-08-13 |
human |
b' Estrella Morenas-Rodr\\xc3\\xadguez, Daniel Alcolea, Marc Su\\xc3\\xa1rez-Calvet, Laia Mu\\xc3\\xb1oz-Llahuna, Eduard Vilaplana, Isabel Sala, Andrea Subirana, Marta Querol-Vilaseca, Mar\\xc3\\xada Carmona-Iragui, Ignacio Ill\\xc3\\xa1n-Gala, Roser Ribosa-Nogu\\xc3\\xa9, Rafael Blesa, Christian Haass, Juan Fortea, Alberto Lle\\xc3\\xb. Different pattern of CSF glial markers between dementia with Lewy bodies and Alzheimer\'s disease. Scientific reports. vol 9. issue 1. 2020-10-15. PMID:31127154.' |
we included patients with dlb (n = 37), prodromal dlb (proddlb, n = 23), ad dementia (n = 50), prodromal ad (prodad, n = 53), and cognitively normal subjects (cn, n = 44). |
2020-10-15 |
2023-08-13 |
human |
Jessica Joanne van der Zande, Alida A Gouw, Inger van Steenoven, Marleen van de Beek, Philip Scheltens, Cornelis Jan Stam, Afina Willemina Lemstr. Diagnostic and prognostic value of EEG in prodromal dementia with Lewy bodies. Neurology. vol 95. issue 6. 2020-10-14. PMID:32636325. |
early biomarkers for dementia with lewy bodies (dlb) are lacking. |
2020-10-14 |
2023-08-13 |
Not clear |
Arvid Rongve, Aree Witoelar, Agustín Ruiz, Lavinia Athanasiu, Carla Abdelnour, Jordi Clarimon, Stefanie Heilmann-Heimbach, Isabel Hernández, Sonia Moreno-Grau, Itziar de Rojas, Estrella Morenas-Rodríguez, Tormod Fladby, Sigrid B Sando, Geir Bråthen, Frédéric Blanc, Olivier Bousiges, Afina W Lemstra, Inger van Steenoven, Elisabet Londos, Ina S Almdahl, Lene Pålhaugen, Jon A Eriksen, Srdjan Djurovic, Eystein Stordal, Ingvild Saltvedt, Ingun D Ulstein, Francesco Bettella, Rahul S Desikan, Ane-Victoria Idland, Mathias Toft, Lasse Pihlstrøm, Jon Snaedal, Lluís Tárraga, Mercè Boada, Alberto Lleó, Hreinn Stefánsson, Kári Stefánsson, Alfredo Ramírez, Dag Aarsland, Ole A Andreasse. GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study. Scientific reports. vol 9. issue 1. 2020-10-13. PMID:31065058. |
dementia with lewy bodies (dlb) is a common neurodegenerative disorder with poor prognosis and mainly unknown pathophysiology. |
2020-10-13 |
2023-08-13 |
Not clear |
Myrto Stylianou, Boubker Zaaimi, Alan Thomas, John-Paul Taylor, Fiona E N LeBea. Early Disruption of Cortical Sleep-Related Oscillations in a Mouse Model of Dementia With Lewy Bodies (DLB) Expressing Human Mutant (A30P) Alpha-Synuclein. Frontiers in neuroscience. vol 14. 2020-10-13. PMID:33041770. |
early disruption of cortical sleep-related oscillations in a mouse model of dementia with lewy bodies (dlb) expressing human mutant (a30p) alpha-synuclein. |
2020-10-13 |
2023-08-13 |
mouse |
Myrto Stylianou, Boubker Zaaimi, Alan Thomas, John-Paul Taylor, Fiona E N LeBea. Early Disruption of Cortical Sleep-Related Oscillations in a Mouse Model of Dementia With Lewy Bodies (DLB) Expressing Human Mutant (A30P) Alpha-Synuclein. Frontiers in neuroscience. vol 14. 2020-10-13. PMID:33041770. |
changes in sleep behavior and sleep-related cortical activity have been reported in conditions associated with abnormal alpha-synuclein (α-syn) expression, in particular parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2020-10-13 |
2023-08-13 |
mouse |
Miguel Lemos, Nadia Stefanov. Histone Deacetylase 6 and the Disease Mechanisms of α-Synucleinopathies. Frontiers in synaptic neuroscience. vol 12. 2020-10-13. PMID:33041780. |
the abnormal accumulation of α-synuclein (α-syn) is a prominent pathological feature in a group of diseases called α-synucleinopathies, such as parkinson's disease, dementia with lewy bodies (dlb), and multiple system atrophy (msa). |
2020-10-13 |
2023-08-13 |
Not clear |
Morgan J Schaeffer, Brandy L Callaha. Investigating the Association Between Verbal Forgetting and Pathological Markers of Alzheimer's and Lewy Body Diseases. Journal of Alzheimer's disease : JAD. vol 70. issue 3. 2020-10-09. PMID:31282412. |
the percentage of verbal forgetting (vf%) measure of the rey auditory verbal learning test (ravlt) has been proposed to differentiate patients diagnosed clinically with alzheimer's disease (ad) and dementia with lewy bodies (dlb). |
2020-10-09 |
2023-08-13 |
Not clear |
Maria Fouka, Panagiota Mavroeidi, Grigoria Tsaka, Maria Xilour. In Search of Effective Treatments Targeting α-Synuclein Toxicity in Synucleinopathies: Pros and Cons. Frontiers in cell and developmental biology. vol 8. 2020-10-06. PMID:33015057. |
parkinson's disease (pd), multiple system atrophy (msa) and dementia with lewy bodies (dlb) represent pathologically similar, progressive neurodegenerative disorders characterized by the pathological aggregation of the neuronal protein α-synuclein. |
2020-10-06 |
2023-08-13 |
Not clear |
Stella Karantzoulis, James E Galvi. UPDATE ON DEMENTIA WITH LEWY BODIES. Current translational geriatrics and experimental gerontology reports. vol 2. issue 3. 2020-10-01. PMID:25379359. |
dementia with lewy bodies (dlb) is the second most common form of dementia after alzheimer disease (ad). |
2020-10-01 |
2023-08-13 |
Not clear |
Alexandre N Rcom-H'cheo-Gauthier, Samantha L Osborne, Adrian C B Meedeniya, Dean L Pountne. Calcium: Alpha-Synuclein Interactions in Alpha-Synucleinopathies. Frontiers in neuroscience. vol 10. 2020-10-01. PMID:28066161. |
aggregation of the pre-synaptic protein, α-synuclein (α-syn), is the key etiological factor in parkinson's disease (pd) and other alpha-synucleinopathies, such as multiple system atrophy (msa) and dementia with lewy bodies (dlb). |
2020-10-01 |
2023-08-13 |
mouse |