| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Babak Tous. Diagnosis and Management of Cognitive and Behavioral Changes in Dementia With Lewy Bodies. Current treatment options in neurology. vol 19. issue 11. 2020-10-01. PMID:28990131. |
reduced uptake on metaiodobenzylguanidine myocardial scintigraphy correlates with reduced postganglionic sympathetic cardiac innervation in lewy body diseases, which can increase specificity for discriminating probable dlb from probable ad in milder cases of dementia. |
2020-10-01 |
2023-08-13 |
Not clear |
| Elisabet Londo. Practical Treatment of Lewy Body Disease in the Clinic: Patient and Physician Perspectives. Neurology and therapy. vol 7. issue 1. 2020-10-01. PMID:29260408. |
this article describes the practical considerations in the clinical medical treatment in dementia with lewy body (dlb) patients. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jana Janssens, Yannick Vermeiren, Erik Fransen, Tony Aerts, Debby Van Dam, Sebastiaan Engelborghs, Peter P De Dey. Cerebrospinal fluid and serum MHPG improve Alzheimer's disease versus dementia with Lewy bodies differential diagnosis. Alzheimer's & dementia (Amsterdam, Netherlands). vol 10. 2020-10-01. PMID:29552632. |
particularly, regarding the ad versus dementia with lewy bodies (dlb) comparison, monoamines or their metabolites might have added discriminative value as there is a more severe neuropathological burden in the locus coeruleus of dlb patients, the principal site of noradrenaline synthesis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Monica H Breitve, Luiza J Chwiszczuk, Kolbjørn Brønnick, Minna J Hynninen, Bjørn H Auestad, Dag Aarsland, Arvid Rongv. A Longitudinal Study of Neurocognition in Dementia with Lewy Bodies Compared to Alzheimer's Disease. Frontiers in neurology. vol 9. 2020-10-01. PMID:29559950. |
there are relatively few longitudinal studies on the differences in cognitive decline between alzheimer's disease (ad) and dementia with lewy bodies (dlb), and the majority of existing studies have suboptimal designs. |
2020-10-01 |
2023-08-13 |
Not clear |
| Paula Garcia-Esparcia, Daniela Diaz-Lucena, Marina Ainciburu, Benjamin Torrejón-Escribano, Margarita Carmona, Franc Llorens, Isidro Ferre. Glutamate Transporter GLT1 Expression in Alzheimer Disease and Dementia With Lewy Bodies. Frontiers in aging neuroscience. vol 10. 2020-10-01. PMID:29755340. |
glutamate transporter solute carrier family 1, member 2 (glt1/eaat2), a major modulator of glutamate homeostasis in astrocytes, is assessed in post-mortem human brain samples of frontal cortex area 8 in advanced stages of alzheimer disease (ad) and terminal stages of dementia with lewy bodies (dlb) in order to gain understanding of astrogliopathy in diseases manifested by dementia. |
2020-10-01 |
2023-08-13 |
human |
| Troy T Rohn, Jacob M Mac. Apolipoprotein E Fragmentation within Lewy Bodies of the Human Parkinson's Disease Brain. International journal of neurodegenerative disorders. vol 1. issue 1. 2020-10-01. PMID:30272057. |
conversely, little staining was observed in the substantia nigra from pick's disease or in the frontal cortex of dementia with lewy bodies (dlb) cases, suggesting a specificity for napoecfp17 immunoreactivity in pd. |
2020-10-01 |
2023-08-13 |
human |
| Laura Brennan, Alexander Pantelyat, John E Duda, James F Morley, Daniel Weintraub, Jayne R Wilkinson, Paul J Mober. Memantine and Cognition in Parkinson's Disease Dementia/Dementia With Lewy Bodies: A Meta-Analysis. Movement disorders clinical practice. vol 3. issue 2. 2020-10-01. PMID:30363483. |
the aim of this work was to utilize meta-analysis in examining the effects of memantine on neuropsychological functioning in patients with parkinson's disease dementia (pdd) and dementia with lewy bodies (dlb). |
2020-10-01 |
2023-08-13 |
Not clear |
| Muhammad L Nasaruddin, Xiaobei Pan, Bernadette McGuinness, Peter Passmore, Patrick G Kehoe, Christian Hölscher, Stewart F Graham, Brian D Gree. Evidence That Parietal Lobe Fatty Acids May Be More Profoundly Affected in Moderate Alzheimer's Disease (AD) Pathology Than in Severe AD Pathology. Metabolites. vol 8. issue 4. 2020-10-01. PMID:30373213. |
these fas were accurately quantified in 27 cognitively normal age-matched controls, 16 cases of moderate alzheimer's disease (ad), 30 severe ad, and 14 dementia with lewy bodies (dlb). |
2020-10-01 |
2023-08-13 |
human |
| David J Irwin, Howard I Hurti. The Contribution of Tau, Amyloid-Beta and Alpha-Synuclein Pathology to Dementia in Lewy Body Disorders. Journal of Alzheimer's disease & Parkinsonism. vol 8. issue 4. 2020-10-01. PMID:30473927. |
parkinson's disease (pd) and the closely related dementia with lewy bodies (dlb) are due to the accumulation of pathogenic alpha-synuclein protein in brain cells manifest by heterogeneous motor and non-motor symptoms, including cognitive impairment and dementia. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yoshiki Takamatsu, Masayo Fujita, Gilbert J Ho, Ryoko Wada, Shuei Sugama, Takato Takenouchi, Masaaki Waragai, Eliezer Masliah, Makoto Hashimot. Motor and Nonmotor Symptoms of Parkinson's Disease: Antagonistic Pleiotropy Phenomena Derived from Parkinson's disease. vol 2018. 2020-10-01. PMID:30595837. |
motor and nonmotor symptoms of parkinson's disease: antagonistic pleiotropy phenomena derived from lewy body diseases, such as parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa), are associated with a wide range of nonmotor symptoms (nms), including cognitive impairment, depression and anxiety, sleep disorders, gastrointestinal symptoms, and autonomic failure. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yuishin Izumi, Ryosuke Miyamoto, Koji Fujita, Yuki Yamamoto, Hirotsugu Yamada, Tomoyasu Matsubara, Yuki Unai, Ai Tsukamoto, Naoko Takamatsu, Hiroyuki Nodera, Shinya Hayashi, Masaya Oda, Atsuko Mori, Yoshihiko Nishida, Shunsuke Watanabe, Hirohisa Ogawa, Hisanori Uehara, Shigeo Murayama, Masataka Sata, Ryuji Kaj. Distinct Incidence of Takotsubo Syndrome Between Amyotrophic Lateral Sclerosis and Synucleinopathies: A Cohort Study. Frontiers in neurology. vol 9. 2020-10-01. PMID:30619056. |
here, we retrospectively examined tts cases in a single-center cohort composed of 250 patients with amyotrophic lateral sclerosis (als) and 870 patients with synucleinopathies [582 patients with parkinson's disease (pd), 125 patients with dementia with lewy bodies (dlb), and 163 patients with multiple system atrophy (msa)] and identified 4 (1.6%, including 2 women) cases with als and no cases with synucleinopathies. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yuka Sugawara Kikuchi, Tetsuo Shimiz. Aripiprazole for the treatment of psychotic symptoms in patients with dementia with Lewy bodies: a case series. Neuropsychiatric disease and treatment. vol 15. 2020-10-01. PMID:30863076. |
the core features of dementia with lewy bodies (dlb) are cognitive fluctuations, visual hallucinations, and parkinsonian symptoms. |
2020-10-01 |
2023-08-13 |
Not clear |
| Sid E O'Bryant, Tanis J Ferman, Fan Zhang, James Hall, Otto Pedraza, Zbigniew K Wszolek, Tori Como, David Julovich, Sravan Mattevada, Leigh A Johnson, Melissa Edwards, James Hall, Neill R Graff-Radfor. A proteomic signature for dementia with Lewy bodies. Alzheimer's & dementia (Amsterdam, Netherlands). vol 11. 2020-10-01. PMID:30923734. |
we sought to determine if a proteomic profile approach developed to detect alzheimer's disease would distinguish patients with lewy body disease from normal controls, and if it would distinguish dementia with lewy bodies (dlb) from parkinson's disease (pd). |
2020-10-01 |
2023-08-13 |
Not clear |
| José Javier Mendoza-Velásquez, Juan Francisco Flores-Vázquez, Evalinda Barrón-Velázquez, Ana Luisa Sosa-Ortiz, Ben-Min Woo Illigens, Timo Siepman. Autonomic Dysfunction in α-Synucleinopathies. Frontiers in neurology. vol 10. 2020-10-01. PMID:31031694. |
the α-synucleinopathies are a group of neurodegenerative diseases characterized by abnormal accumulation of insoluble α-synuclein in neurons and glial cells, comprising parkinson's disease (pd), dementia with lewy bodies (dlb) and multiple system atrophy (msa). |
2020-10-01 |
2023-08-13 |
Not clear |
| Danyan Chen, Jiehui Jiang, Jiaying Lu, Ping Wu, Huiwei Zhang, Chuantao Zuo, Kuangyu Sh. Brain Network and Abnormal Hemispheric Asymmetry Analyses to Explore the Marginal Differences in Glucose Metabolic Distributions Among Alzheimer's Disease, Parkinson's Disease Dementia, and Lewy Body Dementia. Frontiers in neurology. vol 10. 2020-10-01. PMID:31031697. |
facilitating accurate diagnosis and ensuring appropriate treatment of dementia subtypes, including alzheimer's disease (ad), parkinson's disease dementia (pdd), and lewy body dementia (dlb), is clinically important. |
2020-10-01 |
2023-08-13 |
human |
| Marleen van de Beek, Inger van Steenoven, Inez H G B Ramakers, Pauline Aalten, Huiberdina L Koek, Marcel G M Olde Rikkert, Judith Manniën, Janne M Papma, Frank Jan de Jong, Afina W Lemstra, Wiesje M van der Flie. Trajectories and Determinants of Quality of Life in Dementia with Lewy Bodies and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 70. issue 2. 2020-10-01. PMID:31177218. |
research investigating longitudinal qol in dementia with lewy bodies (dlb) is currently lacking. |
2020-10-01 |
2023-08-13 |
Not clear |
| Ying-Jui Ho, Mei-Shiuan Shen, Chun-Hwei Tai, Hsin-Hua Li, Jian-Horng Chen, Wen-Chieh Liao, Pai-Yi Chiu, I-Yen Lee, Chih-Li Lin, Ching-Sui Hun. Use of Ceftriaxone in Treating Cognitive and Neuronal Deficits Associated With Dementia With Lewy Bodies. Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31178684. |
dementia with lewy bodies (dlb) is caused by accumulation of lewy bodies, destruction of mitochondria, and excess of glutamate in synapses, which eventually leads to excitotoxicity, neurodegeneration, and cognitive impairments. |
2020-10-01 |
2023-08-13 |
human |
| Iracema Leroi, Sabina Vatter, Lesley-Anne Carter, Sarah J Smith, Vasiliki Orgeta, Ellen Poliakoff, Monty A Silverdale, Jason Raw, David J Ahearn, Christine Taylor, Joanne Rodda, Tarek Abdel-Ghany, Sheree A McCormic. Parkinson's-adapted cognitive stimulation therapy: a pilot randomized controlled clinical trial. Therapeutic advances in neurological disorders. vol 12. 2020-10-01. PMID:31320931. |
cognitive stimulation therapy (cst) is widely used with people with dementia, but there is no evidence of its efficacy in mild cognitive impairment or dementia in parkinson's disease (pd-mci; pdd) or dementia with lewy bodies (dlb). |
2020-10-01 |
2023-08-13 |
Not clear |
| Kensuke Ikenaka, Mari Suzuki, Hideki Mochizuki, Yoshitaka Naga. Lipids as Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31333408. |
lipids as aggregation of α-synuclein (αsyn) plays a central role in the pathogenesis of parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2020-10-01 |
2023-08-13 |
Not clear |
| Hiroshi Matsuda, Kota Yokoyama, Noriko Sato, Kengo Ito, Kiyotaka Nemoto, Hiroshi Oba, Haruo Hanyu, Hidekazu Kanetaka, Sunao Mizumura, Shin Kitamura, Hitoshi Shinotoh, Hitoshi Shimada, Tetsuya Suhara, Hitoshi Terada, Tomoya Nakatsuka, Shinobu Kawakatsu, Hiroshi Hayashi, Takashi Asada, Tetsutaro Ono, Tomoaki Goto, Keiko Shigemor. Differentiation Between Dementia With Lewy Bodies And Alzheimer's Disease Using Voxel-Based Morphometry Of Structural MRI: A Multicenter Study. Neuropsychiatric disease and treatment. vol 15. 2020-10-01. PMID:31571887. |
the differential diagnosis of dementia with lewy bodies (dlb) and alzheimer's disease (ad) is particularly important because dlb patients respond better to cholinesterase inhibitors but sometimes exhibit sensitivity to neuroleptics, which may cause worsening of clinical status. |
2020-10-01 |
2023-08-13 |
Not clear |