| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K A Jellinge. Morphological substrates of mental dysfunction in Lewy body disease: an update. Journal of neural transmission. Supplementum. vol 59. 2000-12-22. PMID:10961431. |
in dementia with lewy bodies (dlb), the second most frequent cause of dementia in the elderly, cortical lewy bodies (lb) may or may not be associated with amyloid plaques and neuritic ad lesions. |
2000-12-22 |
2023-08-12 |
Not clear |
| S Haïk, J P Brandel, V Sazdovitch, N Delasnerie-Lauprêtre, K Peoc'h, J L Laplanche, N Privat, C Duyckaerts, J L Kemeny, N Kopp, A Laquerrière, M Mohr, J P Deslys, D Dormont, J J Hau. Dementia with Lewy bodies in a neuropathologic series of suspected Creutzfeldt-Jakob disease. Neurology. vol 55. issue 9. 2000-12-22. PMID:11087793. |
discriminating creutzfeldt-jakob disease (cjd) from dementia with lewy bodies (dlb) may be clinically difficult to achieve. |
2000-12-22 |
2023-08-12 |
human |
| R Barber, A Gholkar, P Scheltens, C Ballard, I G McKeith, J T O'Brie. MRI volumetric correlates of white matter lesions in dementia with Lewy bodies and Alzheimer's disease. International journal of geriatric psychiatry. vol 15. issue 10. 2000-11-22. PMID:11044873. |
t(1)-weighted, t(2)-weighted, and proton density mri scans were acquired in subjects with alzheimer's disease (ad, n=25) and dementia with lewy bodies (dlb, n=27). |
2000-11-22 |
2023-08-12 |
human |
| W Samuel, M Caligiuri, D Galasko, J Lacro, M Marini, F S McClure, K Warren, D V Jest. Better cognitive and psychopathologic response to donepezil in patients prospectively diagnosed as dementia with Lewy bodies: a preliminary study. International journal of geriatric psychiatry. vol 15. issue 9. 2000-11-01. PMID:10984725. |
in the present preliminary study, 16 dementia patients were prospectively categorized as having dlb versus ad. |
2000-11-01 |
2023-08-12 |
human |
| E Rockwell, J Choure, D Galasko, J Olichney, D V Jest. Psychopathology at initial diagnosis in dementia with Lewy bodies versus Alzheimer disease: comparison of matched groups with autopsy-confirmed diagnoses. International journal of geriatric psychiatry. vol 15. issue 9. 2000-11-01. PMID:10984728. |
dementia with lewy bodies (dlb) is believed to be the second most common form of dementia, after alzheimer disease (ad). |
2000-11-01 |
2023-08-12 |
Not clear |
| E Rockwell, J Choure, D Galasko, J Olichney, D V Jest. Psychopathology at initial diagnosis in dementia with Lewy bodies versus Alzheimer disease: comparison of matched groups with autopsy-confirmed diagnoses. International journal of geriatric psychiatry. vol 15. issue 9. 2000-11-01. PMID:10984728. |
psychiatric symptoms were more common at time of initial diagnosis of dementia in dlb than in ad patients. |
2000-11-01 |
2023-08-12 |
Not clear |
| E Rockwell, J Choure, D Galasko, J Olichney, D V Jest. Psychopathology at initial diagnosis in dementia with Lewy bodies versus Alzheimer disease: comparison of matched groups with autopsy-confirmed diagnoses. International journal of geriatric psychiatry. vol 15. issue 9. 2000-11-01. PMID:10984728. |
psychopathology should be considered an integral part of dlb, and should be taken into account in the initial diagnosis of the type of dementia. |
2000-11-01 |
2023-08-12 |
Not clear |
| E Iseki, W Marui, H Sawada, K Uéda, K Kosak. Accumulation of human alpha-synuclein in different cytoskeletons in Lewy bodies in brains of dementia with Lewy bodies. Neuroscience letters. vol 290. issue 1. 2000-10-06. PMID:10925170. |
we investigated the origin of alpha-synuclein-immunoreactive components in lewy bodies (lb) in brains of dementia with lewy bodies (dlb) using immunohistochemistry and immunoelectron microscopy with anti-alpha-synuclein antibodies and anti-cytoskeleton antibodies. |
2000-10-06 |
2023-08-12 |
human |
| B C Campbell, Q X Li, J G Culvenor, P Jäkälä, R Cappai, K Beyreuther, C L Masters, C A McLea. Accumulation of insoluble alpha-synuclein in dementia with Lewy bodies. Neurobiology of disease. vol 7. issue 3. 2000-09-12. PMID:10860784. |
we have used western blotting to examine the expression levels and solubility of alpha sn in brain homogenates from dementia with lewy bodies (dlb), parkinson's disease (pd), alzheimer's disease (ad), and normal controls using samples from the parahippocampus/transentorhinal cortex. |
2000-09-12 |
2023-08-12 |
Not clear |
| C Schwab, A J DeMaggio, N Ghoshal, L I Binder, J Kuret, P L McGee. Casein kinase 1 delta is associated with pathological accumulation of tau in several neurodegenerative diseases. Neurobiology of aging. vol 21. issue 4. 2000-09-07. PMID:10924763. |
the distribution of casein kinase 1 delta (cki delta) was studied by immunohistochemistry and correlated with other pathological hallmarks in alzheimer's disease (ad), down syndrome (ds), progressive supranuclear palsy (psp), parkinsonism dementia complex of guam (pdc), pick's disease (pid), pallido-ponto-nigral degeneration (ppnd), parkinson's disease (pd), dementia with lewy bodies (dlb), amyotrophic lateral sclerosis (als), and elderly controls. |
2000-09-07 |
2023-08-12 |
Not clear |
| R Barber, C Ballard, I G McKeith, A Gholkar, J T O'Brie. MRI volumetric study of dementia with Lewy bodies: a comparison with AD and vascular dementia. Neurology. vol 54. issue 6. 2000-08-18. PMID:10746602. |
to compare global and regional atrophy on mri in subjects with dementia with lewy bodies (dlb), ad, vascular dementia (vad), and normal aging. |
2000-08-18 |
2023-08-12 |
human |
| J E Duda, V M Lee, J Q Trojanowsk. Neuropathology of synuclein aggregates. Journal of neuroscience research. vol 61. issue 2. 2000-08-18. PMID:10878583. |
shortly thereafter, alpha-syn was shown to be a major component of lewy bodies (lbs) and lewy neurites in sporadic pd, dementia with lbs (dlb) and the lb variant of ad. |
2000-08-18 |
2023-08-12 |
Not clear |
| R A Armstrong, N J Cairns, P L Lanto. Beta-amyloid deposition in the temporal lobe of patients with dementia with Lewy bodies: comparison with non-demented cases and Alzheimer's disease. Dementia and geriatric cognitive disorders. vol 11. issue 4. 2000-08-16. PMID:10867443. |
beta-amyloid (abeta) deposition in regions of the temporal lobe in patients with dementia with lewy bodies (dlb) was compared with elderly, non-demented (nd) cases and with alzheimer's disease (ad). |
2000-08-16 |
2023-08-12 |
Not clear |
| C Ballard, J O'Brien, A Swann, D Neill, P Lantos, C Holmes, D Burn, P Ince, R Perry, I McKeit. One year follow-up of parkinsonism in dementia with Lewy bodies. Dementia and geriatric cognitive disorders. vol 11. issue 4. 2000-08-16. PMID:10867448. |
the progression of parkinsonism over 1 year was evaluated in a prospective cohort of patients (n = 338), suffering from dementia with lewy bodies (dlb), alzheimer's disease (ad) or vascular dementia (vad). |
2000-08-16 |
2023-08-12 |
Not clear |
| C Ballard, J O'Brien, A Swann, D Neill, P Lantos, C Holmes, D Burn, P Ince, R Perry, I McKeit. One year follow-up of parkinsonism in dementia with Lewy bodies. Dementia and geriatric cognitive disorders. vol 11. issue 4. 2000-08-16. PMID:10867448. |
parkinsonism was frequent at all severities in dlb patients, but usually only present in other dementias when mmse <10. |
2000-08-16 |
2023-08-12 |
Not clear |
| S Collins, A Boyd, A Fletcher, M Gonzales, C A McLean, K Byron, C L Master. Creutzfeldt-Jakob disease: diagnostic utility of 14-3-3 protein immunodetection in cerebrospinal fluid. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 7. issue 3. 2000-08-15. PMID:10833616. |
a negative outcome was 92.5% specific with false positive results seen in five patients with diagnoses which included inflammatory cns disorders, cerebral ischaemia and dementia with lewy bodies (dlb). |
2000-08-15 |
2023-08-12 |
Not clear |
| P F Chinnery, G A Taylor, N Howell, R M Andrews, C M Morris, R W Taylor, I G McKeith, R H Perry, J A Edwardson, D M Turnbul. Mitochondrial DNA haplogroups and susceptibility to AD and dementia with Lewy bodies. Neurology. vol 55. issue 2. 2000-08-15. PMID:10908912. |
the authors analyzed the relationship between nuclear genetic risk factors (apolipoprotein e genotype) and mitochondrial dna (mtdna) sequence variants in pathologically proved cases of ad (n = 185), dementia with lewy bodies (dlb; n = 84), and control subjects (n = 179). |
2000-08-15 |
2023-08-12 |
human |
| T F Chung, J D Sipe, A McKee, R E Fine, B M Schreiber, J S Liang, R J Johnso. Serum amyloid A in Alzheimer's disease brain is predominantly localized to myelin sheaths and axonal membrane. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 7. issue 2. 2000-08-08. PMID:10842712. |
immunohistochemical localization of the injury specific apolipoprotein, acute phase serum amyloid a (a-aposaa), was compared in brains of patients with neuropathologically confirmed alzheimer's disease (ad), multiple sclerosis (ms), parkinson's disease (pd); pick's disease (pick's), dementia with lewy bodies (dlb), coronary artery disease (cad), and schizophrenia. |
2000-08-08 |
2023-08-12 |
Not clear |
| I R Mackenzi. Activated microglia in dementia with Lewy bodies. Neurology. vol 55. issue 1. 2000-08-07. PMID:10891923. |
to investigate the role of cerebral inflammation in dementia with lewy bodies (dlb), activated microglial cells were quantified in postmortem brain tissue. |
2000-08-07 |
2023-08-12 |
human |
| K Lowery, P Mynt, J Aisbett, T Dixon, J O'Brien, C Ballar. Depression in the carers of dementia sufferers: a comparison of the carers of patients suffering from dementia with Lewy bodies and the carers of patients with Alzheimer's disease. Journal of affective disorders. vol 59. issue 1. 2000-08-02. PMID:10814772. |
depression has not previously been studied in the carers of patients suffering from dementia with lewy bodies (dlb). |
2000-08-02 |
2023-08-12 |
Not clear |