Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
K Ohara, S Takauchi, M Kokai, Y Morimura, T Nakajima, Y Morit. Familial dementia with Lewy bodies (DLB). Clinical neuropathology. vol 18. issue 5. 1999-11-19. PMID:10505432. |
although these patients with familial dlb displayed clinical variability, all three siblings showed progressive dementia of early onset and progressive language disorder with paraphasia and difficulty in finding words. |
1999-11-19 |
2023-08-12 |
Not clear |
G K Wenning, C Scherfler, R Granata, S Bösch, M Verny, K R Chaudhuri, K Jellinger, W Poewe, I Litva. Time course of symptomatic orthostatic hypotension and urinary incontinence in patients with postmortem confirmed parkinsonian syndromes: a clinicopathological study. Journal of neurology, neurosurgery, and psychiatry. vol 67. issue 5. 1999-11-19. PMID:10519868. |
although both orthostatic hypotension and urinary incontinence have been reported in a number of parkinsonian syndromes, such as parkinson's disease (pd), multiple system atrophy (msa), dementia with lewy bodies (dlb), corticobasal degeneration (cbd), and progressive supranuclear palsy (psp), differences in the evolution of these features have not been studied systematically in pathologically confirmed cases. |
1999-11-19 |
2023-08-12 |
Not clear |
K L Newell, B T Hyman, J H Growdon, E T Hedley-Whyt. Application of the National Institute on Aging (NIA)-Reagan Institute criteria for the neuropathological diagnosis of Alzheimer disease. Journal of neuropathology and experimental neurology. vol 58. issue 11. 1999-11-17. PMID:10560657. |
we applied this method to 84 brains from subjects with clinical and neuropathological diagnoses of ad (n = 33), non-ad dementing illnesses (n = 34), including dementia with lewy bodies (dlb) and progressive supranuclear palsy (psp), and no neurological disease (n = 17). |
1999-11-17 |
2023-08-12 |
human |
I G McKeith, E K Perry, R H Perr. Report of the second dementia with Lewy body international workshop: diagnosis and treatment. Consortium on Dementia with Lewy Bodies. Neurology. vol 53. issue 5. 1999-11-15. PMID:10496243. |
the second international workshop of the consortium on dementia with lewy bodies (dlb) met to review developments since publication of consensus guidelines for the clinical and pathologic diagnosis of dlb in 1996. |
1999-11-15 |
2023-08-12 |
Not clear |
T Imamura, K Ishii, N Hirono, M Hashimoto, S Tanimukai, H Kazuai, T Hanihara, M Sasaki, E Mor. Visual hallucinations and regional cerebral metabolism in dementia with Lewy bodies (DLB). Neuroreport. vol 10. issue 9. 1999-11-10. PMID:10501530. |
visual hallucinations and regional cerebral metabolism in dementia with lewy bodies (dlb). |
1999-11-10 |
2023-08-12 |
Not clear |
T Imamura, K Ishii, N Hirono, M Hashimoto, S Tanimukai, H Kazuai, T Hanihara, M Sasaki, E Mor. Visual hallucinations and regional cerebral metabolism in dementia with Lewy bodies (DLB). Neuroreport. vol 10. issue 9. 1999-11-10. PMID:10501530. |
to investigate the neurobiological bases of visual hallucinations in dementia with lewy bodies (dlb), regional cerebral glucose metabolism was compared among three patient groups; dlb with visual hallucinations, dlb without visual hallucinations and alzheimer's disease (ad) without visual hallucinations. |
1999-11-10 |
2023-08-12 |
Not clear |
J G Culvenor, C A McLean, S Cutt, B C Campbell, F Maher, P Jäkälä, T Hartmann, K Beyreuther, C L Masters, Q X L. Non-Abeta component of Alzheimer's disease amyloid (NAC) revisited. NAC and alpha-synuclein are not associated with Abeta amyloid. The American journal of pathology. vol 155. issue 4. 1999-11-04. PMID:10514400. |
alpha-synuclein (alphasn), also termed the precursor of the non-abeta component of alzheimer's disease (ad) amyloid (nacp), is a major component of lewy bodies and lewy neurites pathognomonic of parkinson's disease (pd) and dementia with lewy bodies (dlb). |
1999-11-04 |
2023-08-12 |
human |
D S Horoupian, P H Wasserstei. Alzheimer's disease pathology in motor cortex in dementia with Lewy bodies clinically mimicking corticobasal degeneration. Acta neuropathologica. vol 98. issue 3. 1999-10-20. PMID:10483792. |
we report here a 70-year-old woman whose initial clinical presentation suggested corticobasal degeneration, but autopsy revealed dementia with lewy bodies (dlb) with severe alzheimer's disease (ad)-type pathology accentuated in the motor cortex, in conjunction with a high burden of both cortical and brain stem lb. |
1999-10-20 |
2023-08-12 |
Not clear |
J Court, D Spurden, S Lloyd, I McKeith, C Ballard, N Cairns, R Kerwin, R Perry, E Perr. Neuronal nicotinic receptors in dementia with Lewy bodies and schizophrenia: alpha-bungarotoxin and nicotine binding in the thalamus. Journal of neurochemistry. vol 73. issue 4. 1999-10-14. PMID:10501205. |
in another disease associated with psychosis, dementia with lewy bodies (dlb), in which visual hallucinations predominate, reductions in nicotine binding have been identified in various cortical and subcortical regions. |
1999-10-14 |
2023-08-12 |
Not clear |
T Imamura, N Hirono, M Hashimoto, T Shimomura, S Tanimukai, H Kazui, T Hanihara, E Mor. Clinical diagnosis of dementia with Lewy bodies in a Japanese dementia registry. Dementia and geriatric cognitive disorders. vol 10. issue 3. 1999-10-07. PMID:10325448. |
we found 15 patients with dementia with lewy bodies (dlb) and 232 patients with alzheimer's disease (ad) among 327 consecutive patients with mild to moderate dementia in a japanese dementia registry, using the clinical criteria of the consortium on dlb international workshop. |
1999-10-07 |
2023-08-12 |
Not clear |
T Imamura, N Hirono, M Hashimoto, T Shimomura, S Tanimukai, H Kazui, T Hanihara, E Mor. Clinical diagnosis of dementia with Lewy bodies in a Japanese dementia registry. Dementia and geriatric cognitive disorders. vol 10. issue 3. 1999-10-07. PMID:10325448. |
patients with dlb have a unique dementia syndrome even in the stage of mild to moderate cognitive impairments. |
1999-10-07 |
2023-08-12 |
Not clear |
R A Armstrong, N J Cairns, P L Lanto. Laminar distribution of pick bodies, pick cells and Alzheimer disease pathology in the frontal and temporal cortex in Pick's disease. Neuropathology and applied neurobiology. vol 25. issue 4. 1999-10-07. PMID:10476043. |
lesions in alzheimer's disease (ad) and dementia with lewy bodies (dlb) have distinct laminar distributions in the cortex. |
1999-10-07 |
2023-08-12 |
Not clear |
C F Lippa, K Ozawa, D M Mann, K Ishii, T W Smith, S Arawaka, H Mor. Deposition of beta-amyloid subtypes 40 and 42 differentiates dementia with Lewy bodies from Alzheimer disease. Archives of neurology. vol 56. issue 9. 1999-09-23. PMID:10488812. |
in dementia with lewy bodies (dlb), an increase in the amount of cortical abeta occurs without severe cortical neuronal losses. |
1999-09-23 |
2023-08-12 |
Not clear |
Y Kudo, Y Horikawa, T Noda, I Eguchi, Y Watanabe, K Wakabayash. [The clinical features of patients with probable dementia with Lewy bodies--report of 4 cases]. Rinsho shinkeigaku = Clinical neurology. vol 39. issue 4. 1999-09-22. PMID:10391967. |
proposed criteria for the clinical diagnosis of dementia with lewy bodies (dlb). |
1999-09-22 |
2023-08-12 |
Not clear |
Y Kudo, Y Horikawa, T Noda, I Eguchi, Y Watanabe, K Wakabayash. [The clinical features of patients with probable dementia with Lewy bodies--report of 4 cases]. Rinsho shinkeigaku = Clinical neurology. vol 39. issue 4. 1999-09-22. PMID:10391967. |
to evaluate the neurological and psychiatric features, responses to medications, magnetic resonance imaging (mri), and single-photon emission computed tomography (spect) in patients with dlb, we compared the above dlb patients with age- and gender-matched parkinson's disease patients showing no signs of dementia. |
1999-09-22 |
2023-08-12 |
Not clear |
K Ishii, S Yamaji, H Kitagaki, T Imamura, N Hirono, E Mor. Regional cerebral blood flow difference between dementia with Lewy bodies and AD. Neurology. vol 53. issue 2. 1999-09-21. PMID:10430439. |
the authors studied 14 patients with dementia with lewy bodies (dlb), 14 patients with ad, and 14 healthy control subjects with n-isopropyl-p-[123i]iodoamphetamine spect. |
1999-09-21 |
2023-08-12 |
human |
A B Singleton, A M Gibson, I G McKeith, C A Ballard, R H Perry, P G Ince, J A Edwardson, C M Morri. Alpha2-macroglobulin polymorphisms in Alzheimer's disease and dementia with Lewy bodies. Neuroreport. vol 10. issue 7. 1999-09-16. PMID:10380971. |
dementia with lewy bodies (dlb) is the second most common cause of dementia in the elderly after alzheimer's disease (ad). |
1999-09-16 |
2023-08-12 |
Not clear |
C F Lippa, T W Smith, E Perr. Dementia with Lewy bodies: choline acetyltransferase parallels nucleus basalis pathology. Journal of neural transmission (Vienna, Austria : 1996). vol 106. issue 5-6. 1999-09-14. PMID:10443555. |
the biological substrate underlying the reduced cortical choline acetyltransferase (chat) in dementia with lewy bodies (dlb) is incompletely understood. |
1999-09-14 |
2023-08-12 |
Not clear |
C F Lippa, T W Smith, E Perr. Dementia with Lewy bodies: choline acetyltransferase parallels nucleus basalis pathology. Journal of neural transmission (Vienna, Austria : 1996). vol 106. issue 5-6. 1999-09-14. PMID:10443555. |
mean chat levels in the cortex were lower in dementia patients than controls (t = 17.500, p = 0.001), and dlb cases had slightly lower chat levels than ad cases, but this difference was not significant (t = -0.332, p = 0.746). |
1999-09-14 |
2023-08-12 |
Not clear |
M A Piggott, E F Marshall, N Thomas, S Lloyd, J A Court, E Jaros, D Burn, M Johnson, R H Perry, I G McKeith, C Ballard, E K Perr. Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: rostrocaudal distribution. Brain : a journal of neurology. vol 122 ( Pt 8). 1999-09-07. PMID:10430831. |
dementia with lewy bodies (dlb) is a neuropsychiatric disease associated with extrapyramidal features which differ from those of parkinson's disease, including reduced effectiveness of l-dopa and severe sensitivity reactions to neuroleptic drugs. |
1999-09-07 |
2023-08-12 |
Not clear |