| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David J Burn, Elise N Rowan, Thais Minett, Jonathon Sanders, Pat Myint, Jonathon Richardson, Alan Thomas, Jane Newby, Jenny Reid, John T O'Brien, Ian G McKeit. Extrapyramidal features in Parkinson's disease with and without dementia and dementia with Lewy bodies: A cross-sectional comparative study. Movement disorders : official journal of the Movement Disorder Society. vol 18. issue 8. 2004-01-28. PMID:12889077. |
the dementia associated with pd (pdd) closely resembles dementia with lewy bodies (dlb). |
2004-01-28 |
2023-08-12 |
Not clear |
| Takeshi Iwatsub. Aggregation of alpha-synuclein in the pathogenesis of Parkinson's disease. Journal of neurology. vol 250 Suppl 3. 2004-01-28. PMID:14579119. |
lewy bodies (lbs) are hallmark lesions in the brains of patients with parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2004-01-28 |
2023-08-12 |
Not clear |
| Christopher M Morris, Kirsty K O'Brien, Alison M Gibson, John A Hardy, Andrew B Singleto. Polymorphism in the human DJ-1 gene is not associated with sporadic dementia with Lewy bodies or Parkinson's disease. Neuroscience letters. vol 352. issue 2. 2004-01-23. PMID:14625045. |
its role in the development of late onset pd and other lewy body associated disorders such as dementia with lewy bodies (dlb) is however unknown. |
2004-01-23 |
2023-08-12 |
human |
| R A Armstron. Quantifying the pathology of neurodegenerative disorders: quantitative measurements, sampling strategies and data analysis. Histopathology. vol 42. issue 6. 2004-01-22. PMID:12786887. |
these methods are illustrated with reference to particular problems in the pathological diagnosis of ad and dementia with lewy bodies (dlb). |
2004-01-22 |
2023-08-12 |
Not clear |
| Makoto Hashimoto, Edward Rockenstein, Leslie Crews, Eliezer Maslia. Role of protein aggregation in mitochondrial dysfunction and neurodegeneration in Alzheimer's and Parkinson's diseases. Neuromolecular medicine. vol 4. issue 1-2. 2004-01-21. PMID:14528050. |
these include alzheimer's disease (ad), parkinson's disease (pd), and dementia with lewy bodies (dlb). |
2004-01-21 |
2023-08-12 |
Not clear |
| Ian McKeith, Jacobo Mintzer, Dag Aarsland, David Burn, Helen Chiu, Jiska Cohen-Mansfield, Dennis Dickson, Bruno Dubois, John E Duda, Howard Feldman, Serge Gauthier, Glenda Halliday, Brian Lawlor, Carol Lippa, Oscar L Lopez, João Carlos Machado, John O'Brien, Jeremy Playfer, Wayne Rei. Dementia with Lewy bodies. The Lancet. Neurology. vol 3. issue 1. 2004-01-21. PMID:14693108. |
dementia with lewy bodies (dlb) is the second commonest cause of neurodegenerative dementia in older people. |
2004-01-21 |
2023-08-12 |
Not clear |
| Ian McKeith, Jacobo Mintzer, Dag Aarsland, David Burn, Helen Chiu, Jiska Cohen-Mansfield, Dennis Dickson, Bruno Dubois, John E Duda, Howard Feldman, Serge Gauthier, Glenda Halliday, Brian Lawlor, Carol Lippa, Oscar L Lopez, João Carlos Machado, John O'Brien, Jeremy Playfer, Wayne Rei. Dementia with Lewy bodies. The Lancet. Neurology. vol 3. issue 1. 2004-01-21. PMID:14693108. |
dlb has many of the clinical and pathological characteristics of the dementia that occurs during the course of parkinson's disease. |
2004-01-21 |
2023-08-12 |
Not clear |
| Ronit Sharon, Ifat Bar-Joseph, Gudrun E Mirick, Charles N Serhan, Dennis J Selko. Altered fatty acid composition of dopaminergic neurons expressing alpha-synuclein and human brains with alpha-synucleinopathies. The Journal of biological chemistry. vol 278. issue 50. 2004-01-15. PMID:14507911. |
alpha-synuclein (alphas) is an abundant neuronal protein that accumulates in insoluble inclusions in parkinson's disease (pd) and the related disorder, dementia with lewy bodies (dlb). |
2004-01-15 |
2023-08-12 |
mouse |
| J Klucken, P J McLean, E Gomez-Tortosa, M Ingelsson, Bradley T Hyma. Neuritic alterations and neural system dysfunction in Alzheimer's disease and dementia with Lewy bodies. Neurochemical research. vol 28. issue 11. 2004-01-14. PMID:14584822. |
alzheimer's disease (ad) and dementia with lewy bodies (dlb) are neurodegenerative disorders that share progressive dementia as the common major clinical symptom. |
2004-01-14 |
2023-08-12 |
Not clear |
| Makoto Hashimoto, Eliezer Maslia. Cycles of aberrant synaptic sprouting and neurodegeneration in Alzheimer's and dementia with Lewy bodies. Neurochemical research. vol 28. issue 11. 2004-01-14. PMID:14584828. |
alzheimer's disease (ad) and dementia with lewy bodies (dlb) are the most common neurodegenerative disorders affecting the elderly. |
2004-01-14 |
2023-08-12 |
Not clear |
| Hubert H Fernandez, Chuang-Kuo Wu, Brian R Ot. Pharmacotherapy of dementia with Lewy bodies. Expert opinion on pharmacotherapy. vol 4. issue 11. 2004-01-14. PMID:14596656. |
the syndrome of dementia with lewy bodies (dlb) is characterised by the clinical triad of fluctuating cognitive impairment, recurrent visual hallucinations and spontaneous motor features of parkinsonism. |
2004-01-14 |
2023-08-12 |
Not clear |
| Hubert H Fernandez, Chuang-Kuo Wu, Brian R Ot. Pharmacotherapy of dementia with Lewy bodies. Expert opinion on pharmacotherapy. vol 4. issue 11. 2004-01-14. PMID:14596656. |
dementia that precedes or accompanies the onset of spontaneous (i.e., not neuroleptic-induced) parkinsonism is termed dlb. |
2004-01-14 |
2023-08-12 |
Not clear |
| D A Cousins, E J Burton, D Burn, A Gholkar, I G McKeith, J T O'Brie. Atrophy of the putamen in dementia with Lewy bodies but not Alzheimer's disease: an MRI study. Neurology. vol 61. issue 9. 2004-01-14. PMID:14610119. |
to compare the volume of the putamen on mri in subjects with alzheimer's disease (ad) and dementia with lewy bodies (dlb) and age-matched normal control subjects, along with the relationship between putamen volume and severity of both extrapyramidal signs and cognitive impairment. |
2004-01-14 |
2023-08-12 |
human |
| Jian-Hui Zhu, Fengli Guo, John Shelburne, Simon Watkins, Charleen T Ch. Localization of phosphorylated ERK/MAP kinases to mitochondria and autophagosomes in Lewy body diseases. Brain pathology (Zurich, Switzerland). vol 13. issue 4. 2004-01-12. PMID:14655753. |
in addition, substantia nigra neurons from patients with incidental lewy body disease, parkinson disease (pd), and diffuse lewy body dementia (dlb) display abnormal phospho-erk accumulations in the form of discrete cytoplasmic granules. |
2004-01-12 |
2023-08-12 |
Not clear |
| Kurt A Jellinge. Alpha-synuclein pathology in Parkinson's and Alzheimer's disease brain: incidence and topographic distribution--a pilot study. Acta neuropathologica. vol 106. issue 3. 2004-01-09. PMID:12845452. |
to study the incidence and topographic distribution of alpha-synuclein-positive inclusions in parkinson's disease (pd), dementia with lb (dlb), and alzheimer's disease (ad), 206 brains of elderly patients, including 53 patients with clinical pd, 110 autopsy-proven ad cases, 22 with dementia with lb (dlb), 1 case with essential tremor, and 20 age-matched controls were investigated using alpha-synuclein immunohistochemistry. |
2004-01-09 |
2023-08-12 |
Not clear |
| K Mitra, P K Gangopadhaya, S K Da. Parkinsonism plus syndrome--a review. Neurology India. vol 51. issue 2. 2004-01-07. PMID:14570999. |
progressive supranuclear palsy (psp), multiple system atrophy (msa) and dementia with lewy body disease (dlb) are commoner disorders. |
2004-01-07 |
2023-08-12 |
Not clear |
| M J Firbank, S J Colloby, D J Burn, I G McKeith, J T O'Brie. Regional cerebral blood flow in Parkinson's disease with and without dementia. NeuroImage. vol 20. issue 2. 2003-12-19. PMID:14568499. |
tc99 hmpao spect and t1 weighted 3d mri scans were acquired in cognitively intact subjects with parkinson's disease (pd) (n = 31), and in pd subjects with dementia (pdd) (n = 34), healthy controls (n = 37), those with alzheimer's disease (ad) (n = 32), and those with dementia with lewy bodies (dlb) (n = 15). |
2003-12-19 |
2023-08-12 |
human |
| Yoshinobu Wakisaka, Akiko Furuta, Yumihiro Tanizaki, Yutaka Kiyohara, Mitsuo Iida, Toru Iwak. Age-associated prevalence and risk factors of Lewy body pathology in a general population: the Hisayama study. Acta neuropathologica. vol 106. issue 4. 2003-12-17. PMID:12904992. |
in dementia with lewy bodies (dlb), the lewy bodies (lbs) are an essential substrate. |
2003-12-17 |
2023-08-12 |
human |
| Yoshinobu Wakisaka, Akiko Furuta, Yumihiro Tanizaki, Yutaka Kiyohara, Mitsuo Iida, Toru Iwak. Age-associated prevalence and risk factors of Lewy body pathology in a general population: the Hisayama study. Acta neuropathologica. vol 106. issue 4. 2003-12-17. PMID:12904992. |
in addition, the pathology of alzheimer-type dementia (atd) is frequently associated with dlb. |
2003-12-17 |
2023-08-12 |
human |
| Irene Hegeman Richard, Anne Wallace Justus, Nigel H Greig, Frederick Marshall, Roger Kurla. Worsening of motor function and mood in a patient with Parkinson's disease after pharmacologic challenge with oral rivastigmine. Clinical neuropharmacology. vol 25. issue 6. 2003-12-16. PMID:12469000. |
clinicians are faced with the dilemma as to whether or not to treat patients with pd with the acetylcholinesterase inhibitors that are currently approved for use in alzheimer's disease (ad) and that have shown promise in clinical trials of dementia with lewy bodies (dlb). |
2003-12-16 |
2023-08-12 |
Not clear |