Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Yoshihiko Horimoto, Mitsuhiro Matsumoto, Hideka Nakazawa, Hiroyuki Yuasa, Manabu Morishita, Hiroyasu Akatsu, Hiroyuki Ikari, Takayuki Yamamoto, Kenji Kosak. Cognitive conditions of pathologically confirmed dementia with Lewy bodies and Parkinson's disease with dementia. Journal of the neurological sciences. vol 216. issue 1. 2004-02-26. PMID:14607310. |
compared with 10 age-matched cases of definite alzheimer's disease, both 19 dlb cases and 6 pdd cases had significantly better scores in the final test of mini-mental state examination (mmse) and revised version of hasegawa's dementia scale (hdsr) within 12 months before death, although no significant differences between dlb and pdd were indicated. |
2004-02-26 |
2023-08-12 |
Not clear |
Maria J Martí, Eduardo Tolosa, Jaume Campdelacre. Clinical overview of the synucleinopathies. Movement disorders : official journal of the Movement Disorder Society. vol 18 Suppl 6. 2004-02-24. PMID:14502652. |
these disorders include parkinson's disease (pd), dementia with lewy bodies (dlb), pure autonomic failure (paf), and multiple system atrophy (msa). |
2004-02-24 |
2023-08-12 |
Not clear |
David J Burn, Ian G McKeit. Current treatment of dementia with Lewy bodies and dementia associated with Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 18 Suppl 6. 2004-02-24. PMID:14502659. |
clinical and pathological features closely link pdd and dementia with lewy bodies (dlb), suggesting they represent part of the same disease spectrum. |
2004-02-24 |
2023-08-12 |
Not clear |
Rabiya S Tum. When spacing out brings clarity. Mental lapses serve as diagnostic clue for type of dementia. Science of aging knowledge environment : SAGE KE. vol 2004. issue 4. 2004-02-23. PMID:14749519. |
some clinicians think that periodic mental lapses might help diagnose dementia with lewy bodies (dlb), a scourge that kills brain cells (see dlb case study), although not all experts agree. |
2004-02-23 |
2023-08-12 |
Not clear |
S López-Pousa, J Garre-Olmo, A Turon-Estrada, E Gelada-Batle, M Lozano-Gallego, M Hernández-Ferrándiz, V Morante-Muñoz, J Peralta-Rodríguez, M M Cruz-Rein. [Clinical incidence of dementia with Lewy bodies]. Revista de neurologia. vol 36. issue 8. 2004-02-17. PMID:12717647. |
dementia with lewy bodies (dlb) has only relatively recently been acknowledged as an independent neurodegenerative entity. |
2004-02-17 |
2023-08-12 |
Not clear |
S L Pimlott, M Piggott, J Owens, E Greally, J A Court, E Jaros, R H Perry, E K Perry, D Wype. Nicotinic acetylcholine receptor distribution in Alzheimer's disease, dementia with Lewy bodies, Parkinson's disease, and vascular dementia: in vitro binding study using 5-[(125)i]-a-85380. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 1. 2004-02-17. PMID:12955099. |
in dementia with lewy bodies (dlb) reduced striatal 5-[(125)i]-a-85380 binding density, comparable to that in pd, may be a marker of early degeneration in nigrostriatal inputs, while in alzheimer's disease (ad) reduced striatal 5-[(125)i]-a-85380 binding could be related to reduced cortical inputs. |
2004-02-17 |
2023-08-12 |
human |
S L Pimlott, M Piggott, J Owens, E Greally, J A Court, E Jaros, R H Perry, E K Perry, D Wype. Nicotinic acetylcholine receptor distribution in Alzheimer's disease, dementia with Lewy bodies, Parkinson's disease, and vascular dementia: in vitro binding study using 5-[(125)i]-a-85380. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 1. 2004-02-17. PMID:12955099. |
the reductions of nachrs seen in ad, dlb, and pd were not apparent in vascular dementia (vad). |
2004-02-17 |
2023-08-12 |
human |
Karl Herhol. PET studies in dementia. Annals of nuclear medicine. vol 17. issue 2. 2004-02-10. PMID:12790355. |
cortical acetylcholine esterase activity (ache) activity is significantly lower in patients with ad or with dementia with lewy bodies (dlb) than in age-matched normal controls. |
2004-02-10 |
2023-08-12 |
Not clear |
Thaís S C Minett, Alan Thomas, Lucy M Wilkinson, Sarah L Daniel, Jonathan Sanders, Jonathan Richardson, Elizabeth Littlewood, Pat Myint, Jane Newby, Ian G McKeit. What happens when donepezil is suddenly withdrawn? An open label trial in dementia with Lewy bodies and Parkinson's disease with dementia. International journal of geriatric psychiatry. vol 18. issue 11. 2004-02-10. PMID:14618549. |
this open label study was designed to assess the effects of donepezil treatment, its withdrawal and subsequent recommencement on cognitive functioning, behaviour and parkinsonian symptoms in patients with probable dementia with lewy bodies (dlb) and with parkinson's disease who subsequently developed dementia (pdd). |
2004-02-10 |
2023-08-12 |
Not clear |
Christopher Fran. Dementia with Lewy bodies. Review of diagnosis and pharmacologic management. Canadian family physician Medecin de famille canadien. vol 49. 2004-02-04. PMID:14594099. |
to review clinical features of dementia with lewy bodies (dlb) and to guide family physicians in pharmacologic management, including medications to avoid. |
2004-02-04 |
2023-08-12 |
Not clear |
A R Merdes, L A Hansen, D V Jeste, D Galasko, C R Hofstetter, G J Ho, L J Thal, J Corey-Bloo. Influence of Alzheimer pathology on clinical diagnostic accuracy in dementia with Lewy bodies. Neurology. vol 60. issue 10. 2004-01-29. PMID:12771246. |
to determine whether ad neurofibrillary pathology influences clinical diagnostic accuracy in dementia with lewy bodies (dlb). |
2004-01-29 |
2023-08-12 |
Not clear |
David J Burn, Elise N Rowan, Thais Minett, Jonathon Sanders, Pat Myint, Jonathon Richardson, Alan Thomas, Jane Newby, Jenny Reid, John T O'Brien, Ian G McKeit. Extrapyramidal features in Parkinson's disease with and without dementia and dementia with Lewy bodies: A cross-sectional comparative study. Movement disorders : official journal of the Movement Disorder Society. vol 18. issue 8. 2004-01-28. PMID:12889077. |
the dementia associated with pd (pdd) closely resembles dementia with lewy bodies (dlb). |
2004-01-28 |
2023-08-12 |
Not clear |
Takeshi Iwatsub. Aggregation of alpha-synuclein in the pathogenesis of Parkinson's disease. Journal of neurology. vol 250 Suppl 3. 2004-01-28. PMID:14579119. |
lewy bodies (lbs) are hallmark lesions in the brains of patients with parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2004-01-28 |
2023-08-12 |
Not clear |
Christopher M Morris, Kirsty K O'Brien, Alison M Gibson, John A Hardy, Andrew B Singleto. Polymorphism in the human DJ-1 gene is not associated with sporadic dementia with Lewy bodies or Parkinson's disease. Neuroscience letters. vol 352. issue 2. 2004-01-23. PMID:14625045. |
its role in the development of late onset pd and other lewy body associated disorders such as dementia with lewy bodies (dlb) is however unknown. |
2004-01-23 |
2023-08-12 |
human |
R A Armstron. Quantifying the pathology of neurodegenerative disorders: quantitative measurements, sampling strategies and data analysis. Histopathology. vol 42. issue 6. 2004-01-22. PMID:12786887. |
these methods are illustrated with reference to particular problems in the pathological diagnosis of ad and dementia with lewy bodies (dlb). |
2004-01-22 |
2023-08-12 |
Not clear |
Makoto Hashimoto, Edward Rockenstein, Leslie Crews, Eliezer Maslia. Role of protein aggregation in mitochondrial dysfunction and neurodegeneration in Alzheimer's and Parkinson's diseases. Neuromolecular medicine. vol 4. issue 1-2. 2004-01-21. PMID:14528050. |
these include alzheimer's disease (ad), parkinson's disease (pd), and dementia with lewy bodies (dlb). |
2004-01-21 |
2023-08-12 |
Not clear |
Ian McKeith, Jacobo Mintzer, Dag Aarsland, David Burn, Helen Chiu, Jiska Cohen-Mansfield, Dennis Dickson, Bruno Dubois, John E Duda, Howard Feldman, Serge Gauthier, Glenda Halliday, Brian Lawlor, Carol Lippa, Oscar L Lopez, João Carlos Machado, John O'Brien, Jeremy Playfer, Wayne Rei. Dementia with Lewy bodies. The Lancet. Neurology. vol 3. issue 1. 2004-01-21. PMID:14693108. |
dementia with lewy bodies (dlb) is the second commonest cause of neurodegenerative dementia in older people. |
2004-01-21 |
2023-08-12 |
Not clear |
Ian McKeith, Jacobo Mintzer, Dag Aarsland, David Burn, Helen Chiu, Jiska Cohen-Mansfield, Dennis Dickson, Bruno Dubois, John E Duda, Howard Feldman, Serge Gauthier, Glenda Halliday, Brian Lawlor, Carol Lippa, Oscar L Lopez, João Carlos Machado, John O'Brien, Jeremy Playfer, Wayne Rei. Dementia with Lewy bodies. The Lancet. Neurology. vol 3. issue 1. 2004-01-21. PMID:14693108. |
dlb has many of the clinical and pathological characteristics of the dementia that occurs during the course of parkinson's disease. |
2004-01-21 |
2023-08-12 |
Not clear |
Ronit Sharon, Ifat Bar-Joseph, Gudrun E Mirick, Charles N Serhan, Dennis J Selko. Altered fatty acid composition of dopaminergic neurons expressing alpha-synuclein and human brains with alpha-synucleinopathies. The Journal of biological chemistry. vol 278. issue 50. 2004-01-15. PMID:14507911. |
alpha-synuclein (alphas) is an abundant neuronal protein that accumulates in insoluble inclusions in parkinson's disease (pd) and the related disorder, dementia with lewy bodies (dlb). |
2004-01-15 |
2023-08-12 |
mouse |
J Klucken, P J McLean, E Gomez-Tortosa, M Ingelsson, Bradley T Hyma. Neuritic alterations and neural system dysfunction in Alzheimer's disease and dementia with Lewy bodies. Neurochemical research. vol 28. issue 11. 2004-01-14. PMID:14584822. |
alzheimer's disease (ad) and dementia with lewy bodies (dlb) are neurodegenerative disorders that share progressive dementia as the common major clinical symptom. |
2004-01-14 |
2023-08-12 |
Not clear |