| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jianjia Fan, James Donkin, Cheryl Wellingto. Greasing the wheels of Abeta clearance in Alzheimer's disease: the role of lipids and apolipoprotein E. BioFactors (Oxford, England). vol 35. issue 3. 2009-08-25. PMID:19472365. |
these studies provide new insights into the mechanisms by which apoe affects abeta metabolism, and offer opportunities to develop novel therapeutic approaches to reduce the leading cause of dementia in the elderly. |
2009-08-25 |
2023-08-12 |
mouse |
| Caroline H Williams-Gray, An Goris, Misuzu Saiki, Thomas Foltynie, D Alastair S Compston, Stephen J Sawcer, Roger A Barke. Apolipoprotein E genotype as a risk factor for susceptibility to and dementia in Parkinson's disease. Journal of neurology. vol 256. issue 3. 2009-08-10. PMID:19308307. |
further to the well-established association between apolipoprotein e (apoe) and alzheimer's disease, this gene has also been implicated in both susceptibility to, and dementia in, parkinson's disease (pd). |
2009-08-10 |
2023-08-12 |
Not clear |
| Roger M Lane, Yunsheng H. Emerging hypotheses regarding the influences of butyrylcholinesterase-K variant, APOE epsilon 4, and hyperhomocysteinemia in neurodegenerative dementias. Medical hypotheses. vol 73. issue 2. 2009-08-05. PMID:19359103. |
emerging hypotheses regarding the influences of butyrylcholinesterase-k variant, apoe epsilon 4, and hyperhomocysteinemia in neurodegenerative dementias. |
2009-08-05 |
2023-08-12 |
Not clear |
| James A Mortimer, David A Snowdon, William R Markesber. The effect of APOE-epsilon4 on dementia is mediated by Alzheimer neuropathology. Alzheimer disease and associated disorders. vol 23. issue 2. 2009-07-23. PMID:19484916. |
the present study was undertaken to determine the roles of alzheimer disease (ad) and vascular pathology in mediating the effect of apolipoprotein e (apoe)-epsilon4 alleles on dementia. |
2009-07-23 |
2023-08-12 |
Not clear |
| b' Marianna Trebunov\\xc3\\xa1, Eva Slab\\xc3\\xa1, Viera Habalov\\xc3\\xa1, Zuzana Gdovinov\\xc3\\xa. The role of the -427T/C apolipoprotein E promoter polymorphism in the pathogenesis of Alzheimer\'s disease, vascular dementia and mixed dementia. Journal of neural transmission (Vienna, Austria : 1996). vol 116. issue 3. 2009-07-01. PMID:19142571.' |
we investigated newly reported -427t/c promoter polymorphism in association with sporadic alzheimer's disease (ad), vascular (vd) and mixed dementia (md) along with apoe genotype and gender. |
2009-07-01 |
2023-08-12 |
human |
| V P Prasher, S G Sajith, S D Rees, A Patel, S Tewari, N Schupf, W B Zigma. Significant effect of APOE epsilon 4 genotype on the risk of dementia in Alzheimer's disease and mortality in persons with Down syndrome. International journal of geriatric psychiatry. vol 23. issue 11. 2009-05-21. PMID:18464295. |
significant effect of apoe epsilon 4 genotype on the risk of dementia in alzheimer's disease and mortality in persons with down syndrome. |
2009-05-21 |
2023-08-12 |
Not clear |
| L A Pemberton, E Stone, P Price, F van Bockxmeer, B J Bre. The relationship between ApoE, TNFA, IL1a, IL1b and IL12b genes and HIV-1-associated dementia. HIV medicine. vol 9. issue 8. 2009-05-14. PMID:18631256. |
the relationship between apoe, tnfa, il1a, il1b and il12b genes and hiv-1-associated dementia. |
2009-05-14 |
2023-08-12 |
Not clear |
| Mario Ezquerra, Jaume Campdelacreu, Carles Gaig, Yaroslau Compta, Esteban Muñoz, Maria Jose Martí, Francesc Valldeoriola, Eduardo Tolos. Lack of association of APOE and tau polymorphisms with dementia in Parkinson's disease. Neuroscience letters. vol 448. issue 1. 2009-04-16. PMID:18930114. |
lack of association of apoe and tau polymorphisms with dementia in parkinson's disease. |
2009-04-16 |
2023-08-12 |
Not clear |
| Mario Ezquerra, Jaume Campdelacreu, Carles Gaig, Yaroslau Compta, Esteban Muñoz, Maria Jose Martí, Francesc Valldeoriola, Eduardo Tolos. Lack of association of APOE and tau polymorphisms with dementia in Parkinson's disease. Neuroscience letters. vol 448. issue 1. 2009-04-16. PMID:18930114. |
the reports of a possible association between the apoe 4 allele and dementia in pd are controversial, and some studies suggest that the tau h1/h1 genotype may increase the risk of dementia in pd. |
2009-04-16 |
2023-08-12 |
Not clear |
| Mario Ezquerra, Jaume Campdelacreu, Carles Gaig, Yaroslau Compta, Esteban Muñoz, Maria Jose Martí, Francesc Valldeoriola, Eduardo Tolos. Lack of association of APOE and tau polymorphisms with dementia in Parkinson's disease. Neuroscience letters. vol 448. issue 1. 2009-04-16. PMID:18930114. |
here we analysed these apoe and tau polymorphisms in 86 clinically diagnosed pd patients with dementia (pdd), in 138 clinically diagnosed non-demented pd (pdnd) patients, and in 91 healthy controls. |
2009-04-16 |
2023-08-12 |
Not clear |
| Mario Ezquerra, Jaume Campdelacreu, Carles Gaig, Yaroslau Compta, Esteban Muñoz, Maria Jose Martí, Francesc Valldeoriola, Eduardo Tolos. Lack of association of APOE and tau polymorphisms with dementia in Parkinson's disease. Neuroscience letters. vol 448. issue 1. 2009-04-16. PMID:18930114. |
the effects of tau and apoe polymorphisms on the age at dementia onset were studied using kaplan-meier survival analysis but no significant association were found. |
2009-04-16 |
2023-08-12 |
Not clear |
| Mario Ezquerra, Jaume Campdelacreu, Carles Gaig, Yaroslau Compta, Esteban Muñoz, Maria Jose Martí, Francesc Valldeoriola, Eduardo Tolos. Lack of association of APOE and tau polymorphisms with dementia in Parkinson's disease. Neuroscience letters. vol 448. issue 1. 2009-04-16. PMID:18930114. |
the lack of association between the apoe 4 allele and pdd suggests that the pathological process involved in the development of dementia in pd is different from the one that occurs in ad. |
2009-04-16 |
2023-08-12 |
Not clear |
| Kristel Sleegers, Karolien Bettens, Nathalie Brouwers, Sebastiaan Engelborghs, Helen van Miegroet, Peter P De Deyn, Christine Van Broeckhove. Common variation in GRB-associated Binding Protein 2 (GAB2) and increased risk for Alzheimer dementia. Human mutation. vol 30. issue 2. 2009-04-10. PMID:18853460. |
grb-associated binding protein 2 (gab2) was recently reported to be a modifier of late-onset alzheimer dementia (ad) risk in carriers of the apoe epsilon4 allele in a genome-wide association analysis. |
2009-04-10 |
2023-08-12 |
Not clear |
| Nunzio Pomara, Kenneth D Belzer, Raul Silva, Thomas B Cooper, John J Sidti. The apolipoprotein E epsilon4 allele and memory performance in HIV-1 seropositive subjects: differences at baseline but not after acute oral lorazepam challenge. Psychopharmacology. vol 201. issue 1. 2009-04-07. PMID:18668226. |
the apoe epsilon4 allele, an established genetic risk factor for late-onset alzheimer's disease, has been linked to an increased risk for dementia especially in older individuals with hiv-1 infection. |
2009-04-07 |
2023-08-12 |
human |
| Kathryn Sawyer, Natalie Sachs-Ericsson, Kristopher J Preacher, Dan G Blaze. Racial differences in the influence of the APOE epsilon 4 allele on cognitive decline in a sample of community-dwelling older adults. Gerontology. vol 55. issue 1. 2009-04-02. PMID:18525196. |
most, but not all, past studies have suggested that the apoe genotype is a risk factor for dementia in whites but not african americans. |
2009-04-02 |
2023-08-12 |
Not clear |
| Miia Kivipelto, Suvi Rovio, Tiia Ngandu, Ingemar Kåreholt, Marjo Eskelinen, Bengt Winblad, Vladimir Hachinski, Angel Cedazo-Minguez, Hilkka Soininen, Jaakko Tuomilehto, Aulikki Nissine. Apolipoprotein E epsilon4 magnifies lifestyle risks for dementia: a population-based study. Journal of cellular and molecular medicine. vol 12. issue 6B. 2009-03-25. PMID:18318693. |
the aim of this study was to investigate the effects and putative interactions between the apoe epsilon4 allele and lifestyle related risk factors for dementia and ad. |
2009-03-25 |
2023-08-12 |
human |
| Miia Kivipelto, Suvi Rovio, Tiia Ngandu, Ingemar Kåreholt, Marjo Eskelinen, Bengt Winblad, Vladimir Hachinski, Angel Cedazo-Minguez, Hilkka Soininen, Jaakko Tuomilehto, Aulikki Nissine. Apolipoprotein E epsilon4 magnifies lifestyle risks for dementia: a population-based study. Journal of cellular and molecular medicine. vol 12. issue 6B. 2009-03-25. PMID:18318693. |
physical inactivity, dietary fat intake, alcohol drinking and smoking at midlife are associated with the risk of dementia and ad, especially among the apoe epsilon4 carriers. |
2009-03-25 |
2023-08-12 |
human |
| Miia Kivipelto, Suvi Rovio, Tiia Ngandu, Ingemar Kåreholt, Marjo Eskelinen, Bengt Winblad, Vladimir Hachinski, Angel Cedazo-Minguez, Hilkka Soininen, Jaakko Tuomilehto, Aulikki Nissine. Apolipoprotein E epsilon4 magnifies lifestyle risks for dementia: a population-based study. Journal of cellular and molecular medicine. vol 12. issue 6B. 2009-03-25. PMID:18318693. |
the apoe epsilon4 carriers may be more vulnerable to environmental factors, and thus, lifestyle interventions may greatly modify dementia risk particularly among the genetically susceptible individuals. |
2009-03-25 |
2023-08-12 |
human |
| Deborah M Little, Valerie C Crooks, Diana B Petitti, Vicki Chiu, Gerard D Schellenberg, Jeff M Slezak, Steven J Jacobse. Mortality, dementia, and apolipoprotein E genotype in elderly white women in the United States. Journal of the American Geriatrics Society. vol 57. issue 2. 2009-03-02. PMID:19207139. |
to assess the risk of death in relation to apolipoprotein e (apoe) genotype and to evaluate how apoe genotype interacts with dementia and with other major medical conditions to affect survival. |
2009-03-02 |
2023-08-12 |
Not clear |
| P Pandey, S Pradhan, B Mitta. LRP-associated protein gene (LRPAP1) and susceptibility to degenerative dementia. Genes, brain, and behavior. vol 7. issue 8. 2009-02-27. PMID:18721259. |
the aim of this study was to investigate variations in two lipid metabolizing genes, low-density lipoprotein receptor-related protein-associated protein gene (lrpap) and apolipoprotein e (apoe), in vascular and degenerative dementias. |
2009-02-27 |
2023-08-12 |
Not clear |